Analysis of the p16 gene (CDKN2) as a candidate for the chromosome 9p melanoma susceptibility locus.
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Times Cited: 523
Times Cited: 523
Times Cited
Times Co-cited
Similarity
Germline p16 mutations in familial melanoma.
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Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma.
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TERT promoter mutations in familial and sporadic melanoma.
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Prevalence of p16 and CDK4 germline mutations in 48 melanoma-prone families in France. The French Familial Melanoma Study Group.
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POT1 loss-of-function variants predispose to familial melanoma.
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Carla Daniela Robles-Espinoza, Mark Harland, Andrew J Ramsay, Lauren G Aoude, Víctor Quesada, Zhihao Ding, Karen A Pooley, Antonia L Pritchard, Jessamy C Tiffen, Mia Petljak,[...]. Nat Genet 2014
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A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma.
Satoru Yokoyama, Susan L Woods, Glen M Boyle, Lauren G Aoude, Stuart MacGregor, Victoria Zismann, Michael Gartside, Anne E Cust, Rizwan Haq, Mark Harland,[...]. Nature 2011
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Features associated with germline CDKN2A mutations: a GenoMEL study of melanoma-prone families from three continents.
Alisa M Goldstein, May Chan, Mark Harland, Nicholas K Hayward, Florence Demenais, D Timothy Bishop, Esther Azizi, Wilma Bergman, Giovanna Bianchi-Scarra, William Bruno,[...]. J Med Genet 2007
Alisa M Goldstein, May Chan, Mark Harland, Nicholas K Hayward, Florence Demenais, D Timothy Bishop, Esther Azizi, Wilma Bergman, Giovanna Bianchi-Scarra, William Bruno,[...]. J Med Genet 2007
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A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma.
Corine Bertolotto, Fabienne Lesueur, Sandy Giuliano, Thomas Strub, Mahaut de Lichy, Karine Bille, Philippe Dessen, Benoit d'Hayer, Hamida Mohamdi, Audrey Remenieras,[...]. Nature 2011
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18
Rare missense variants in POT1 predispose to familial cutaneous malignant melanoma.
Jianxin Shi, Xiaohong R Yang, Bari Ballew, Melissa Rotunno, Donato Calista, Maria Concetta Fargnoli, Paola Ghiorzo, Brigitte Bressac-de Paillerets, Eduardo Nagore, Marie Francoise Avril,[...]. Nat Genet 2014
Jianxin Shi, Xiaohong R Yang, Bari Ballew, Melissa Rotunno, Donato Calista, Maria Concetta Fargnoli, Paola Ghiorzo, Brigitte Bressac-de Paillerets, Eduardo Nagore, Marie Francoise Avril,[...]. Nat Genet 2014
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A landscape of driver mutations in melanoma.
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High frequency of BRAF mutations in nevi.
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Nonsense mutations in the shelterin complex genes ACD and TERF2IP in familial melanoma.
Lauren G Aoude, Antonia L Pritchard, Carla Daniela Robles-Espinoza, Karin Wadt, Mark Harland, Jiyeon Choi, Michael Gartside, Víctor Quesada, Peter Johansson, Jane M Palmer,[...]. J Natl Cancer Inst 2014
Lauren G Aoude, Antonia L Pritchard, Carla Daniela Robles-Espinoza, Karin Wadt, Mark Harland, Jiyeon Choi, Michael Gartside, Víctor Quesada, Peter Johansson, Jane M Palmer,[...]. J Natl Cancer Inst 2014
16
Geographical variation in the penetrance of CDKN2A mutations for melanoma.
D Timothy Bishop, Florence Demenais, Alisa M Goldstein, Wilma Bergman, Julia Newton Bishop, Brigitte Bressac-de Paillerets, Agnès Chompret, Paola Ghiorzo, Nelleke Gruis, Johan Hansson,[...]. J Natl Cancer Inst 2002
D Timothy Bishop, Florence Demenais, Alisa M Goldstein, Wilma Bergman, Julia Newton Bishop, Brigitte Bressac-de Paillerets, Agnès Chompret, Paola Ghiorzo, Nelleke Gruis, Johan Hansson,[...]. J Natl Cancer Inst 2002
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Distinct sets of genetic alterations in melanoma.
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A cell cycle regulator potentially involved in genesis of many tumor types.
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Mutations of the BRAF gene in human cancer.
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Melanoma prone families with CDK4 germline mutation: phenotypic profile and associations with MC1R variants.
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High-risk melanoma susceptibility genes and pancreatic cancer, neural system tumors, and uveal melanoma across GenoMEL.
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Genetics of familial melanoma: 20 years after CDKN2A.
Lauren G Aoude, Karin A W Wadt, Antonia L Pritchard, Nicholas K Hayward. Pigment Cell Melanoma Res 2015
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Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma.
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The Genetic Evolution of Melanoma from Precursor Lesions.
A Hunter Shain, Iwei Yeh, Ivanka Kovalyshyn, Aravindhan Sriharan, Eric Talevich, Alexander Gagnon, Reinhard Dummer, Jeffrey North, Laura Pincus, Beth Ruben,[...]. N Engl J Med 2015
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Germline mutations in BAP1 predispose to melanocytic tumors.
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A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4.
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Highly recurrent TERT promoter mutations in human melanoma.
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Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma.
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Somatic activation of KIT in distinct subtypes of melanoma.
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Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers.
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Selection criteria for genetic assessment of patients with familial melanoma.
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Assignment of a locus for familial melanoma, MLM, to chromosome 9p13-p22.
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Improved survival with vemurafenib in melanoma with BRAF V600E mutation.
Paul B Chapman, Axel Hauschild, Caroline Robert, John B Haanen, Paolo Ascierto, James Larkin, Reinhard Dummer, Claus Garbe, Alessandro Testori, Michele Maio,[...]. N Engl J Med 2011
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Inhibition of mutated, activated BRAF in metastatic melanoma.
Keith T Flaherty, Igor Puzanov, Kevin B Kim, Antoni Ribas, Grant A McArthur, Jeffrey A Sosman, Peter J O'Dwyer, Richard J Lee, Joseph F Grippo, Keith Nolop,[...]. N Engl J Med 2010
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A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1.
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A Nonsynonymous Variant in the GOLM1 Gene in Cutaneous Malignant Melanoma.
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Frequent mutation of BAP1 in metastasizing uveal melanomas.
J William Harbour, Michael D Onken, Elisha D O Roberson, Shenghui Duan, Li Cao, Lori A Worley, M Laurin Council, Katie A Matatall, Cynthia Helms, Anne M Bowcock. Science 2010
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9
Genome-wide association study identifies three new melanoma susceptibility loci.
Jennifer H Barrett, Mark M Iles, Mark Harland, John C Taylor, Joanne F Aitken, Per Arne Andresen, Lars A Akslen, Bruce K Armstrong, Marie-Francoise Avril, Esther Azizi,[...]. Nat Genet 2011
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9
Braf(V600E) cooperates with Pten loss to induce metastatic melanoma.
David Dankort, David P Curley, Robert A Cartlidge, Betsy Nelson, Anthony N Karnezis, William E Damsky, Mingjian J You, Ronald A DePinho, Martin McMahon, Marcus Bosenberg. Nat Genet 2009
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9
Genome-wide meta-analysis identifies five new susceptibility loci for cutaneous malignant melanoma.
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Signatures of mutational processes in human cancer.
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9
Lifetime risk of melanoma in CDKN2A mutation carriers in a population-based sample.
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8
Genome-wide association study identifies a new melanoma susceptibility locus at 1q21.3.
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A large Norwegian family with inherited malignant melanoma, multiple atypical nevi, and CDK4 mutation.
Anders Molven, Magne B Grimstvedt, Solrun J Steine, Mark Harland, Marie-Françoise Avril, Nicholas K Hayward, Lars A Akslen. Genes Chromosomes Cancer 2005
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11
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Genome-wide association study identifies novel loci predisposing to cutaneous melanoma.
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7
Genome-wide association study identifies three loci associated with melanoma risk.
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Increased risk of pancreatic cancer in melanoma-prone kindreds with p16INK4 mutations.
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BRAFE600-associated senescence-like cell cycle arrest of human naevi.
Chrysiis Michaloglou, Liesbeth C W Vredeveld, Maria S Soengas, Christophe Denoyelle, Thomas Kuilman, Chantal M A M van der Horst, Donné M Majoor, Jerry W Shay, Wolter J Mooi, Daniel S Peeper. Nature 2005
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Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi.
Catherine D Van Raamsdonk, Vladimir Bezrookove, Gary Green, Jürgen Bauer, Lona Gaugler, Joan M O'Brien, Elizabeth M Simpson, Gregory S Barsh, Boris C Bastian. Nature 2009
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7
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.