I S Trowbridge, M L Thomas. Annu Rev Immunol 1994
Times Cited: 671
Times Cited: 671
Times Cited
Times Co-cited
Similarity
CD45: a critical regulator of signaling thresholds in immune cells.
Michelle L Hermiston, Zheng Xu, Arthur Weiss. Annu Rev Immunol 2003
Michelle L Hermiston, Zheng Xu, Arthur Weiss. Annu Rev Immunol 2003
23
Negative regulation of CD45 by differential homodimerization of the alternatively spliced isoforms.
Zheng Xu, Arthur Weiss. Nat Immunol 2002
Zheng Xu, Arthur Weiss. Nat Immunol 2002
9
The differential regulation of Lck kinase phosphorylation sites by CD45 is critical for T cell receptor signaling responses.
Louise McNeill, Robert J Salmond, Joanne C Cooper, Céline K Carret, Robin L Cassady-Cain, Marta Roche-Molina, Panna Tandon, Nick Holmes, Denis R Alexander. Immunity 2007
Louise McNeill, Robert J Salmond, Joanne C Cooper, Céline K Carret, Robin L Cassady-Cain, Marta Roche-Molina, Panna Tandon, Nick Holmes, Denis R Alexander. Immunity 2007
7
6
A human memory T cell subset with stem cell-like properties.
Luca Gattinoni, Enrico Lugli, Yun Ji, Zoltan Pos, Chrystal M Paulos, Máire F Quigley, Jorge R Almeida, Emma Gostick, Zhiya Yu, Carmine Carpenito,[...]. Nat Med 2011
Luca Gattinoni, Enrico Lugli, Yun Ji, Zoltan Pos, Chrystal M Paulos, Máire F Quigley, Jorge R Almeida, Emma Gostick, Zhiya Yu, Carmine Carpenito,[...]. Nat Med 2011
6
Consequences of regulated pre-mRNA splicing in the immune system.
Kristen W Lynch. Nat Rev Immunol 2004
Kristen W Lynch. Nat Rev Immunol 2004
6
The kinetic-segregation model: TCR triggering and beyond.
Simon J Davis, P Anton van der Merwe. Nat Immunol 2006
Simon J Davis, P Anton van der Merwe. Nat Immunol 2006
5
Mutations in the tyrosine phosphatase CD45 gene in a child with severe combined immunodeficiency disease.
C Kung, J T Pingel, M Heikinheimo, T Klemola, K Varkila, L I Yoo, K Vuopala, M Poyhonen, M Uhari, M Rogers,[...]. Nat Med 2000
C Kung, J T Pingel, M Heikinheimo, T Klemola, K Varkila, L I Yoo, K Vuopala, M Poyhonen, M Uhari, M Rogers,[...]. Nat Med 2000
5
A point mutation in PTPRC is associated with the development of multiple sclerosis.
M Jacobsen, D Schweer, A Ziegler, R Gaber, S Schock, R Schwinzer, K Wonigeit, R B Lindert, O Kantarci, J Schaefer-Klein,[...]. Nat Genet 2000
M Jacobsen, D Schweer, A Ziegler, R Gaber, S Schock, R Schwinzer, K Wonigeit, R B Lindert, O Kantarci, J Schaefer-Klein,[...]. Nat Genet 2000
5
Differential usage of three exons generates at least five different mRNAs encoding human leukocyte common antigens.
M Streuli, L R Hall, Y Saga, S F Schlossman, H Saito. J Exp Med 1987
M Streuli, L R Hall, Y Saga, S F Schlossman, H Saito. J Exp Med 1987
5
CD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturation.
K F Byth, L A Conroy, S Howlett, A J Smith, J May, D R Alexander, N Holmes. J Exp Med 1996
K F Byth, L A Conroy, S Howlett, A J Smith, J May, D R Alexander, N Holmes. J Exp Med 1996
5
A CD45 polymorphism associated with multiple sclerosis disrupts an exonic splicing silencer.
K W Lynch, A Weiss. J Biol Chem 2001
K W Lynch, A Weiss. J Biol Chem 2001
5
Evidence that the leukocyte-common antigen is required for antigen-induced T lymphocyte proliferation.
J T Pingel, M L Thomas. Cell 1989
J T Pingel, M L Thomas. Cell 1989
4
Changes in CD45 isoform expression accompany antigen-induced murine T-cell activation.
M L Birkeland, P Johnson, I S Trowbridge, E Puré. Proc Natl Acad Sci U S A 1989
M L Birkeland, P Johnson, I S Trowbridge, E Puré. Proc Natl Acad Sci U S A 1989
4
Receptor-like tyrosine phosphatases CD45 and CD148 have distinct functions in chemoattractant-mediated neutrophil migration and response to S. aureus.
Jing W Zhu, Kristin Doan, Jason Park, Angela H Chau, Hong Zhang, Clifford A Lowell, Arthur Weiss. Immunity 2011
Jing W Zhu, Kristin Doan, Jason Park, Angela H Chau, Hong Zhang, Clifford A Lowell, Arthur Weiss. Immunity 2011
10
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources.
Da Wei Huang, Brad T Sherman, Richard A Lempicki. Nat Protoc 2009
Da Wei Huang, Brad T Sherman, Richard A Lempicki. Nat Protoc 2009
4
CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling.
J Irie-Sasaki, T Sasaki, W Matsumoto, A Opavsky, M Cheng, G Welstead, E Griffiths, C Krawczyk, C D Richardson, K Aitken,[...]. Nature 2001
J Irie-Sasaki, T Sasaki, W Matsumoto, A Opavsky, M Cheng, G Welstead, E Griffiths, C Krawczyk, C D Richardson, K Aitken,[...]. Nature 2001
4
A C-type lectin collaborates with a CD45 phosphatase homolog to facilitate West Nile virus infection of mosquitoes.
Gong Cheng, Jonathan Cox, Penghua Wang, Manoj N Krishnan, Jianfeng Dai, Feng Qian, John F Anderson, Erol Fikrig. Cell 2010
Gong Cheng, Jonathan Cox, Penghua Wang, Manoj N Krishnan, Jianfeng Dai, Feng Qian, John F Anderson, Erol Fikrig. Cell 2010
4
A deletion in the gene encoding the CD45 antigen in a patient with SCID.
E Z Tchilian, D L Wallace, R S Wells, D R Flower, G Morgan, P C Beverley. J Immunol 2001
E Z Tchilian, D L Wallace, R S Wells, D R Flower, G Morgan, P C Beverley. J Immunol 2001
4
Normal B lymphocyte development but impaired T cell maturation in CD45-exon6 protein tyrosine phosphatase-deficient mice.
K Kishihara, J Penninger, V A Wallace, T M Kündig, K Kawai, A Wakeham, E Timms, K Pfeffer, P S Ohashi, M L Thomas. Cell 1993
K Kishihara, J Penninger, V A Wallace, T M Kündig, K Kawai, A Wakeham, E Timms, K Pfeffer, P S Ohashi, M L Thomas. Cell 1993
4
Control of regulatory T cell development by the transcription factor Foxp3.
Shohei Hori, Takashi Nomura, Shimon Sakaguchi. Science 2003
Shohei Hori, Takashi Nomura, Shimon Sakaguchi. Science 2003
4
Protein tyrosine phosphatases as potential therapeutic targets.
Rong-Jun He, Zhi-Hong Yu, Ruo-Yu Zhang, Zhong-Yin Zhang. Acta Pharmacol Sin 2014
Rong-Jun He, Zhi-Hong Yu, Ruo-Yu Zhang, Zhong-Yin Zhang. Acta Pharmacol Sin 2014
4
Modulation of immune cell signalling by the leukocyte common tyrosine phosphatase, CD45.
A E Saunders, P Johnson. Cell Signal 2010
A E Saunders, P Johnson. Cell Signal 2010
4
An inactivating point mutation in the inhibitory wedge of CD45 causes lymphoproliferation and autoimmunity.
R Majeti, Z Xu, T G Parslow, J L Olson, D I Daikh, N Killeen, A Weiss. Cell 2000
R Majeti, Z Xu, T G Parslow, J L Olson, D I Daikh, N Killeen, A Weiss. Cell 2000
4
Global analysis of alternative splicing during T-cell activation.
Joanna Y Ip, Alan Tong, Qun Pan, Justin D Topp, Benjamin J Blencowe, Kristen W Lynch. RNA 2007
Joanna Y Ip, Alan Tong, Qun Pan, Justin D Topp, Benjamin J Blencowe, Kristen W Lynch. RNA 2007
4
Regulation of CD45 alternative splicing by heterogeneous ribonucleoprotein, hnRNPLL.
Shalini Oberdoerffer, Luis Ferreira Moita, Daniel Neems, Rui P Freitas, Nir Hacohen, Anjana Rao. Science 2008
Shalini Oberdoerffer, Luis Ferreira Moita, Daniel Neems, Rui P Freitas, Nir Hacohen, Anjana Rao. Science 2008
4
Alternative splicing networks regulated by signaling in human T cells.
Nicole M Martinez, Qun Pan, Brian S Cole, Christopher A Yarosh, Grace A Babcock, Florian Heyd, William Zhu, Sandya Ajith, Benjamin J Blencowe, Kristen W Lynch. RNA 2012
Nicole M Martinez, Qun Pan, Brian S Cole, Christopher A Yarosh, Grace A Babcock, Florian Heyd, William Zhu, Sandya Ajith, Benjamin J Blencowe, Kristen W Lynch. RNA 2012
5
Loss of CD45R and gain of UCHL1 reactivity is a feature of primed T cells.
A N Akbar, L Terry, A Timms, P C Beverley, G Janossy. J Immunol 1988
A N Akbar, L Terry, A Timms, P C Beverley, G Janossy. J Immunol 1988
4
Comparison of CD45 extracellular domain sequences from divergent vertebrate species suggests the conservation of three fibronectin type III domains.
M Okumura, R J Matthews, B Robb, G W Litman, P Bork, M L Thomas. J Immunol 1996
M Okumura, R J Matthews, B Robb, G W Litman, P Bork, M L Thomas. J Immunol 1996
8
Two subsets of memory T lymphocytes with distinct homing potentials and effector functions.
F Sallusto, D Lenig, R Förster, M Lipp, A Lanzavecchia. Nature 1999
F Sallusto, D Lenig, R Förster, M Lipp, A Lanzavecchia. Nature 1999
4
The large ectodomains of CD45 and CD148 regulate their segregation from and inhibition of ligated T-cell receptor.
Shaun-Paul Cordoba, Kaushik Choudhuri, Hao Zhang, Marcus Bridge, Alp Bugra Basat, Michael L Dustin, P Anton van der Merwe. Blood 2013
Shaun-Paul Cordoba, Kaushik Choudhuri, Hao Zhang, Marcus Bridge, Alp Bugra Basat, Michael L Dustin, P Anton van der Merwe. Blood 2013
6
Lifespan of human lymphocyte subsets defined by CD45 isoforms.
C A Michie, A McLean, C Alcock, P C Beverley. Nature 1992
C A Michie, A McLean, C Alcock, P C Beverley. Nature 1992
4
T-cell receptor triggering is critically dependent on the dimensions of its peptide-MHC ligand.
Kaushik Choudhuri, David Wiseman, Marion H Brown, Keith Gould, P Anton van der Merwe. Nature 2005
Kaushik Choudhuri, David Wiseman, Marion H Brown, Keith Gould, P Anton van der Merwe. Nature 2005
3
Positive and negative selection of T cells.
Timothy K Starr, Stephen C Jameson, Kristin A Hogquist. Annu Rev Immunol 2003
Timothy K Starr, Stephen C Jameson, Kristin A Hogquist. Annu Rev Immunol 2003
3
T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster.
Rajat Varma, Gabriele Campi, Tadashi Yokosuka, Takashi Saito, Michael L Dustin. Immunity 2006
Rajat Varma, Gabriele Campi, Tadashi Yokosuka, Takashi Saito, Michael L Dustin. Immunity 2006
3
Characterization of recombinant CD45 cytoplasmic domain proteins. Evidence for intramolecular and intermolecular interactions.
J Felberg, P Johnson. J Biol Chem 1998
J Felberg, P Johnson. J Biol Chem 1998
4
Mutational analysis of Lck in CD45-negative T cells: dominant role of tyrosine 394 phosphorylation in kinase activity.
U D'Oro, K Sakaguchi, E Appella, J D Ashwell. Mol Cell Biol 1996
U D'Oro, K Sakaguchi, E Appella, J D Ashwell. Mol Cell Biol 1996
3
Structural basis for the function and regulation of the receptor protein tyrosine phosphatase CD45.
Hyun-Joo Nam, Florence Poy, Haruo Saito, Christin A Frederick. J Exp Med 2005
Hyun-Joo Nam, Florence Poy, Haruo Saito, Christin A Frederick. J Exp Med 2005
3
TU-572, a potent and selective CD45 inhibitor, suppresses IgE-mediated anaphylaxis and murine contact hypersensitivity reactions.
T Hamaguchi, A Takahashi, A Manaka, M Sato, H Osada. Int Arch Allergy Immunol 2001
T Hamaguchi, A Takahashi, A Manaka, M Sato, H Osada. Int Arch Allergy Immunol 2001
21
3
Phenotypic and functional separation of memory and effector human CD8+ T cells.
D Hamann, P A Baars, M H Rep, B Hooibrink, S R Kerkhof-Garde, M R Klein, R A van Lier. J Exp Med 1997
D Hamann, P A Baars, M H Rep, B Hooibrink, S R Kerkhof-Garde, M R Klein, R A van Lier. J Exp Med 1997
3
CD45 regulates Src family member kinase activity associated with macrophage integrin-mediated adhesion.
T Roach, S Slater, M Koval, L White, E D Cahir McFarland, M Okumura, M Thomas, E Brown. Curr Biol 1997
T Roach, S Slater, M Koval, L White, E D Cahir McFarland, M Okumura, M Thomas, E Brown. Curr Biol 1997
3
Enhanced frequency of a PTPRC (CD45) exon A mutation (77C-->G) in systemic sclerosis.
R Schwinzer, T Witte, J Hundrieser, S Ehlers, T Momot, N Hunzelmann, T Krieg, R E Schmidt, K Wonigeit. Genes Immun 2003
R Schwinzer, T Witte, J Hundrieser, S Ehlers, T Momot, N Hunzelmann, T Krieg, R E Schmidt, K Wonigeit. Genes Immun 2003
6
Molecular defects in human severe combined immunodeficiency and approaches to immune reconstitution.
Rebecca H Buckley. Annu Rev Immunol 2004
Rebecca H Buckley. Annu Rev Immunol 2004
3
CD45: new jobs for an old acquaintance.
J M Penninger, J Irie-Sasaki, T Sasaki, A J Oliveira-dos-Santos. Nat Immunol 2001
J M Penninger, J Irie-Sasaki, T Sasaki, A J Oliveira-dos-Santos. Nat Immunol 2001
3
A point mutation in CD45 may be associated with an increased risk of HIV-1 infection.
E Z Tchilian, D L Wallace, R Dawes, N Imami, C Burton, F Gotch, P C Beverley. AIDS 2001
E Z Tchilian, D L Wallace, R Dawes, N Imami, C Burton, F Gotch, P C Beverley. AIDS 2001
6
PTPRC (CD45) is not associated with the development of multiple sclerosis in U.S. patients.
L F Barcellos, S Caillier, L Dragone, M Elder, E Vittinghoff, P Bucher, R R Lincoln, M Pericak-Vance, J L Haines, A Weiss,[...]. Nat Genet 2001
L F Barcellos, S Caillier, L Dragone, M Elder, E Vittinghoff, P Bucher, R R Lincoln, M Pericak-Vance, J L Haines, A Weiss,[...]. Nat Genet 2001
5
Altered CD45 expression in C77G carriers influences immune function and outcome of hepatitis C infection.
R Dawes, B Hennig, W Irving, S Petrova, S Boxall, V Ward, D Wallace, D C Macallan, M Thursz, A Hill,[...]. J Med Genet 2006
R Dawes, B Hennig, W Irving, S Petrova, S Boxall, V Ward, D Wallace, D C Macallan, M Thursz, A Hill,[...]. J Med Genet 2006
15
The catalytic activity of the CD45 membrane-proximal phosphatase domain is required for TCR signaling and regulation.
D M Desai, J Sap, O Silvennoinen, J Schlessinger, A Weiss. EMBO J 1994
D M Desai, J Sap, O Silvennoinen, J Schlessinger, A Weiss. EMBO J 1994
3
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.