A citation-based method for searching scientific literature

L M Warner, L M Adams, S N Sehgal. Arthritis Rheum 1994
Times Cited: 128







List of co-cited articles
1232 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Rapamycin reduces disease activity and normalizes T cell activation-induced calcium fluxing in patients with systemic lupus erythematosus.
David Fernandez, Eduardo Bonilla, Naureen Mirza, Brian Niland, Andras Perl. Arthritis Rheum 2006
200
69

Activation of mammalian target of rapamycin controls the loss of TCRzeta in lupus T cells through HRES-1/Rab4-regulated lysosomal degradation.
David R Fernandez, Tiffany Telarico, Eduardo Bonilla, Qing Li, Sanjay Banerjee, Frank A Middleton, Paul E Phillips, Mary K Crow, Stefanie Oess, Werner Muller-Esterl,[...]. J Immunol 2009
148
39

The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2.
Greg M Delgoffe, Kristen N Pollizzi, Adam T Waickman, Emily Heikamp, David J Meyers, Maureen R Horton, Bo Xiao, Paul F Worley, Jonathan D Powell. Nat Immunol 2011
707
24

N-acetylcysteine reduces disease activity by blocking mammalian target of rapamycin in T cells from systemic lupus erythematosus patients: a randomized, double-blind, placebo-controlled trial.
Zhi-Wei Lai, Robert Hanczko, Eduardo Bonilla, Tiffany N Caza, Brandon Clair, Adam Bartos, Gabriella Miklossy, John Jimah, Edward Doherty, Hajra Tily,[...]. Arthritis Rheum 2012
198
22

Sirolimus in patients with clinically active systemic lupus erythematosus resistant to, or intolerant of, conventional medications: a single-arm, open-label, phase 1/2 trial.
Zhi-Wei Lai, Ryan Kelly, Thomas Winans, Ivan Marchena, Ashwini Shadakshari, Julie Yu, Maha Dawood, Ricardo Garcia, Hajra Tily, Lisa Francis,[...]. Lancet 2018
149
22

Rapamycin attenuates the severity of established nephritis in lupus-prone NZB/W F1 mice.
Sing Leung Lui, Ryan Tsang, Kwok Wah Chan, Florence Zhang, Sidney Tam, Susan Yung, Tak Mao Chan. Nephrol Dial Transplant 2008
56
35

Mitochondrial hyperpolarization and ATP depletion in patients with systemic lupus erythematosus.
Peter Gergely, Craig Grossman, Brian Niland, Ferenc Puskas, Hom Neupane, Fatme Allam, Katalin Banki, Paul E Phillips, Andras Perl. Arthritis Rheum 2002
201
19

Mechanistic target of rapamycin activation triggers IL-4 production and necrotic death of double-negative T cells in patients with systemic lupus erythematosus.
Zhi-Wei Lai, Rebecca Borsuk, Ashwini Shadakshari, Jianghong Yu, Maha Dawood, Ricardo Garcia, Lisa Francis, Hajra Tily, Adam Bartos, Stephen V Faraone,[...]. J Immunol 2013
75
25

Prevention of murine lupus disease in (NZBxNZW)F1 mice by sirolimus treatment.
A Ramos-Barrón, C Piñera-Haces, C Gómez-Alamillo, I Santiuste-Torcida, J C Ruiz, L Buelta-Carrillo, R Merino, A L M de Francisco, M Arias. Lupus 2007
38
47

Rapamycin prevents the development of nephritis in lupus-prone NZB/W F1 mice.
S L Lui, S Yung, R Tsang, F Zhang, K W Chan, S Tam, T M Chan. Lupus 2008
42
42

Systemic lupus erythematosus.
George C Tsokos. N Engl J Med 2011
18


Deficient CD4+CD25high T regulatory cell function in patients with active systemic lupus erythematosus.
Xavier Valencia, Cheryl Yarboro, Gabor Illei, Peter E Lipsky. J Immunol 2007
429
17


Inhibition of the mTORC pathway in the antiphospholipid syndrome.
Guillaume Canaud, Frank Bienaimé, Fanny Tabarin, Guillaume Bataillon, Danielle Seilhean, Laure-Hélène Noël, Marie-Agnès Dragon-Durey, Renaud Snanoudj, Gérard Friedlander, Lise Halbwachs-Mecarelli,[...]. N Engl J Med 2014
168
16

The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment.
Greg M Delgoffe, Thomas P Kole, Yan Zheng, Paul E Zarek, Krystal L Matthews, Bo Xiao, Paul F Worley, Sara C Kozma, Jonathan D Powell. Immunity 2009
784
14

Normalization of CD4+ T cell metabolism reverses lupus.
Yiming Yin, Seung-Chul Choi, Zhiwei Xu, Daniel J Perry, Howard Seay, Byron P Croker, Eric S Sobel, Todd M Brusko, Laurence Morel. Sci Transl Med 2015
291
14

Mitochondrial Dysfunction in the Liver and Antiphospholipid Antibody Production Precede Disease Onset and Respond to Rapamycin in Lupus-Prone Mice.
Zachary Oaks, Thomas Winans, Tiffany Caza, David Fernandez, Yuxin Liu, Steve K Landas, Katalin Banki, Andras Perl. Arthritis Rheumatol 2016
52
26

Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB.
Dos D Sarbassov, Siraj M Ali, Shomit Sengupta, Joon-Ho Sheen, Peggy P Hsu, Alex F Bagley, Andrew L Markhard, David M Sabatini. Mol Cell 2006
13

mTOR regulates memory CD8 T-cell differentiation.
Koichi Araki, Alexandra P Turner, Virginia Oliva Shaffer, Shivaprakash Gangappa, Susanne A Keller, Martin F Bachmann, Christian P Larsen, Rafi Ahmed. Nature 2009
996
13

Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets.
Ryan D Michalek, Valerie A Gerriets, Sarah R Jacobs, Andrew N Macintyre, Nancie J MacIver, Emily F Mason, Sarah A Sullivan, Amanda G Nichols, Jeffrey C Rathmell. J Immunol 2011
13

HRES-1/Rab4-mediated depletion of Drp1 impairs mitochondrial homeostasis and represents a target for treatment in SLE.
Tiffany N Caza, David R Fernandez, Gergely Talaber, Zachary Oaks, Mark Haas, Michael P Madaio, Zhi-Wei Lai, Gabriella Miklossy, Ram R Singh, Dmitriy M Chudakov,[...]. Ann Rheum Dis 2014
76
17

Mitochondrial hyperpolarization: a checkpoint of T-cell life, death and autoimmunity.
Andras Perl, Peter Gergely, Gyorgy Nagy, Agnes Koncz, Katalin Banki. Trends Immunol 2004
159
12


Expanded double negative T cells in patients with systemic lupus erythematosus produce IL-17 and infiltrate the kidneys.
José C Crispín, Mohamed Oukka, George Bayliss, Robert A Cohen, Christine A Van Beek, Isaac E Stillman, Vasileios C Kyttaris, Yuang-Taung Juang, George C Tsokos. J Immunol 2008
482
12

The PI3K/Akt/mTOR pathway is activated in murine lupus nephritis and downregulated by rapamycin.
Kostas Stylianou, Ioannis Petrakis, Vasiliki Mavroeidi, Stavros Stratakis, Eleftheria Vardaki, Kostas Perakis, Spyros Stratigis, Andreas Passam, Eva Papadogiorgaki, Kostas Giannakakis,[...]. Nephrol Dial Transplant 2011
57
21

Nitric oxide-dependent mitochondrial biogenesis generates Ca2+ signaling profile of lupus T cells.
Gyorgy Nagy, Maureen Barcza, Nick Gonchoroff, Paul E Phillips, Andras Perl. J Immunol 2004
80
13

FKBP12-rapamycin-associated protein associates with mitochondria and senses osmotic stress via mitochondrial dysfunction.
Bimal N Desai, Benjamin R Myers, Stuart L Schreiber. Proc Natl Acad Sci U S A 2002
192
11


HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells.
Lewis Z Shi, Ruoning Wang, Gonghua Huang, Peter Vogel, Geoffrey Neale, Douglas R Green, Hongbo Chi. J Exp Med 2011
982
11

The 1982 revised criteria for the classification of systemic lupus erythematosus.
E M Tan, A S Cohen, J F Fries, A T Masi, D J McShane, N F Rothfield, J G Schaller, N Talal, R J Winchester. Arthritis Rheum 1982
11


Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells.
Manuela Battaglia, Angela Stabilini, Maria-Grazia Roncarolo. Blood 2005
867
9


Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex.
D D Sarbassov, David A Guertin, Siraj M Ali, David M Sabatini. Science 2005
9

Rapamycin promotes expansion of functional CD4+CD25+FOXP3+ regulatory T cells of both healthy subjects and type 1 diabetic patients.
Manuela Battaglia, Angela Stabilini, Barbara Migliavacca, Jutta Horejs-Hoeck, Thomas Kaupper, Maria-Grazia Roncarolo. J Immunol 2006
527
9


The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells.
Sokol Haxhinasto, Diane Mathis, Christophe Benoist. J Exp Med 2008
553
9

PI3Kgamma inhibition blocks glomerulonephritis and extends lifespan in a mouse model of systemic lupus.
Domingo F Barber, Almira Bartolomé, Carmen Hernandez, Juana M Flores, Clara Redondo, Cristina Fernandez-Arias, Montserrat Camps, Thomas Rückle, Matthias K Schwarz, Santiago Rodríguez,[...]. Nat Med 2005
247
9

Enhancing CD8 T-cell memory by modulating fatty acid metabolism.
Erika L Pearce, Matthew C Walsh, Pedro J Cejas, Gretchen M Harms, Hao Shen, Li-San Wang, Russell G Jones, Yongwon Choi. Nature 2009
921
9

The CD28 signaling pathway regulates glucose metabolism.
Kenneth A Frauwirth, James L Riley, Marian H Harris, Richard V Parry, Jeffrey C Rathmell, David R Plas, Rebecca L Elstrom, Carl H June, Craig B Thompson. Immunity 2002
839
9

Activation of a metabolic gene regulatory network downstream of mTOR complex 1.
Katrin Düvel, Jessica L Yecies, Suchithra Menon, Pichai Raman, Alex I Lipovsky, Amanda L Souza, Ellen Triantafellow, Qicheng Ma, Regina Gorski, Stephen Cleaver,[...]. Mol Cell 2010
9

Control of T(H)17/T(reg) balance by hypoxia-inducible factor 1.
Eric V Dang, Joseph Barbi, Huang-Yu Yang, Dilini Jinasena, Hong Yu, Ying Zheng, Zachary Bordman, Juan Fu, Young Kim, Hung-Rong Yen,[...]. Cell 2011
881
9

Comprehensive metabolome analyses reveal N-acetylcysteine-responsive accumulation of kynurenine in systemic lupus erythematosus: implications for activation of the mechanistic target of rapamycin.
Andras Perl, Robert Hanczko, Zhi-Wei Lai, Zachary Oaks, Ryan Kelly, Rebecca Borsuk, John M Asara, Paul E Phillips. Metabolomics 2015
66
13


Systemic lupus erythematosus.
Anisur Rahman, David A Isenberg. N Engl J Med 2008
8

Metabolic control of T cell activation and death in SLE.
David Fernandez, Andras Perl. Autoimmun Rev 2009
70
11

T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR.
Stephan Sauer, Ludovica Bruno, Arnulf Hertweck, David Finlay, Marion Leleu, Mikhail Spivakov, Zachary A Knight, Bradley S Cobb, Doreen Cantrell, Eric O'Connor,[...]. Proc Natl Acad Sci U S A 2008
621
8

Shared signaling networks active in B cells isolated from genetically distinct mouse models of lupus.
Tianfu Wu, Xiangmei Qin, Zoran Kurepa, Kirthi Raman Kumar, Kui Liu, Hasna Kanta, Xin J Zhou, Anne B Satterthwaite, Laurie S Davis, Chandra Mohan. J Clin Invest 2007
62
12

An orally bioavailable spleen tyrosine kinase inhibitor delays disease progression and prolongs survival in murine lupus.
Frances Rena Bahjat, Polly R Pine, Andrea Reitsma, Gail Cassafer, Muhammad Baluom, Sunny Grillo, Betty Chang, Fei Fei Zhao, Donald G Payan, Elliott B Grossbard,[...]. Arthritis Rheum 2008
120
8


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.