A citation-based method for searching scientific literature

B Kremer, P Goldberg, S E Andrew, J Theilmann, H Telenius, J Zeisler, F Squitieri, B Lin, A Bassett, E Almqvist. N Engl J Med 1994
Times Cited: 416







List of co-cited articles
884 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity



Huntington's disease: from molecular pathogenesis to clinical treatment.
Christopher A Ross, Sarah J Tabrizi. Lancet Neurol 2011
868
14

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain.
M DiFiglia, E Sapp, K O Chase, S W Davies, G P Bates, J P Vonsattel, N Aronin. Science 1997
13

Venezuelan kindreds reveal that genetic and environmental factors modulate Huntington's disease age of onset.
Nancy S Wexler, Judith Lorimer, Julie Porter, Fidela Gomez, Carol Moskowitz, Edith Shackell, Karen Marder, Graciela Penchaszadeh, Simone A Roberts, Javier Gayán,[...]. Proc Natl Acad Sci U S A 2004
471
13

Phenotypic characterization of individuals with 30-40 CAG repeats in the Huntington disease (HD) gene reveals HD cases with 36 repeats and apparently normal elderly individuals with 36-39 repeats.
D C Rubinsztein, J Leggo, R Coles, E Almqvist, V Biancalana, J J Cassiman, K Chotai, M Connarty, D Crauford, A Curtis,[...]. Am J Hum Genet 1996
339
13

Huntington disease: natural history, biomarkers and prospects for therapeutics.
Christopher A Ross, Elizabeth H Aylward, Edward J Wild, Douglas R Langbehn, Jeffrey D Long, John H Warner, Rachael I Scahill, Blair R Leavitt, Julie C Stout, Jane S Paulsen,[...]. Nat Rev Neurol 2014
501
13

Huntington disease.
J P Vonsattel, M DiFiglia. J Neuropathol Exp Neurol 1998
12

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice.
L Mangiarini, K Sathasivam, M Seller, B Cozens, A Harper, C Hetherington, M Lawton, Y Trottier, H Lehrach, S W Davies,[...]. Cell 1996
12

The incidence and prevalence of Huntington's disease: a systematic review and meta-analysis.
Tamara Pringsheim, Katie Wiltshire, Lundy Day, Jonathan Dykeman, Thomas Steeves, Nathalie Jette. Mov Disord 2012
260
12

Huntington's disease.
Francis O Walker. Lancet 2007
11

The relationship between trinucleotide (CAG) repeat length and clinical features of Huntington's disease.
S E Andrew, Y P Goldberg, B Kremer, H Telenius, J Theilmann, S Adam, E Starr, F Squitieri, B Lin, M A Kalchman. Nat Genet 1993
785
10

HTT haplotypes contribute to differences in Huntington disease prevalence between Europe and East Asia.
Simon C Warby, Henk Visscher, Jennifer A Collins, Crystal N Doty, Catherine Carter, Stefanie L Butland, Anna R Hayden, Ichiro Kanazawa, Colin J Ross, Michael R Hayden. Eur J Hum Genet 2011
98
10

DNA haplotype analysis of Huntington disease reveals clues to the origins and mechanisms of CAG expansion and reasons for geographic variations of prevalence.
F Squitieri, S E Andrew, Y P Goldberg, B Kremer, N Spence, J Zeisler, K Nichol, J Theilmann, J Greenberg, J Goto. Hum Mol Genet 1994
144
10

Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease.
C Zuccato, A Ciammola, D Rigamonti, B R Leavitt, D Goffredo, L Conti, M E MacDonald, R M Friedlander, V Silani, M R Hayden,[...]. Science 2001
910
9

Neuropathological classification of Huntington's disease.
J P Vonsattel, R H Myers, T J Stevens, R J Ferrante, E D Bird, E P Richardson. J Neuropathol Exp Neurol 1985
9


CAG expansion in the Huntington disease gene is associated with a specific and targetable predisposing haplogroup.
Simon C Warby, Alexandre Montpetit, Anna R Hayden, Jeffrey B Carroll, Stefanie L Butland, Henk Visscher, Jennifer A Collins, Alicia Semaka, Thomas J Hudson, Michael R Hayden. Am J Hum Genet 2009
131
9


Prevalence of adult Huntington's disease in the UK based on diagnoses recorded in general practice records.
Stephen J W Evans, Ian Douglas, Michael D Rawlins, Nancy S Wexler, Sarah J Tabrizi, Liam Smeeth. J Neurol Neurosurg Psychiatry 2013
100
8

The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription.
J S Steffan, A Kazantsev, O Spasic-Boskovic, M Greenwald, Y Z Zhu, H Gohler, E E Wanker, G P Bates, D E Housman, L M Thompson. Proc Natl Acad Sci U S A 2000
775
8

Relationship between trinucleotide repeat expansion and phenotypic variation in Huntington's disease.
R G Snell, J C MacMillan, J P Cheadle, I Fenton, L P Lazarou, P Davies, M E MacDonald, J F Gusella, P S Harper, D J Shaw. Nat Genet 1993
583
8

CAG repeat expansion in Huntington disease determines age at onset in a fully dominant fashion.
J-M Lee, E M Ramos, J-H Lee, T Gillis, J S Mysore, M R Hayden, S C Warby, P Morrison, M Nance, C A Ross,[...]. Neurology 2012
184
8

A polymorphic DNA marker genetically linked to Huntington's disease.
J F Gusella, N S Wexler, P M Conneally, S L Naylor, M A Anderson, R E Tanzi, P C Watkins, K Ottina, M R Wallace, A Y Sakaguchi. Nature 1983
8

Huntington disease.
Gillian P Bates, Ray Dorsey, James F Gusella, Michael R Hayden, Chris Kay, Blair R Leavitt, Martha Nance, Christopher A Ross, Rachael I Scahill, Ronald Wetzel,[...]. Nat Rev Dis Primers 2015
522
8

Biological and clinical manifestations of Huntington's disease in the longitudinal TRACK-HD study: cross-sectional analysis of baseline data.
Sarah J Tabrizi, Douglas R Langbehn, Blair R Leavitt, Raymund Ac Roos, Alexandra Durr, David Craufurd, Christopher Kennard, Stephen L Hicks, Nick C Fox, Rachael I Scahill,[...]. Lancet Neurol 2009
620
7

Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease.
Kirupa Sathasivam, Andreas Neueder, Theresa A Gipson, Christian Landles, Agnesska C Benjamin, Marie K Bondulich, Donna L Smith, Richard L M Faull, Raymund A C Roos, David Howland,[...]. Proc Natl Acad Sci U S A 2013
252
7

Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes.
J Nasir, S B Floresco, J R O'Kusky, V M Diewert, J M Richman, J Zeisler, A Borowski, J D Marth, A G Phillips, M R Hayden. Cell 1995
581
7



CAG size-specific risk estimates for intermediate allele repeat instability in Huntington disease.
Alicia Semaka, Chris Kay, Crystal Doty, Jennifer A Collins, Emilia K Bijlsma, Fiona Richards, Y Paul Goldberg, Michael R Hayden. J Med Genet 2013
43
16

Nonallele-specific silencing of mutant and wild-type huntingtin demonstrates therapeutic efficacy in Huntington's disease mice.
Ryan L Boudreau, Jodi L McBride, Inês Martins, Shihao Shen, Yi Xing, Barrie J Carter, Beverly L Davidson. Mol Ther 2009
238
7

Trinucleotide repeat length instability and age of onset in Huntington's disease.
M Duyao, C Ambrose, R Myers, A Novelletto, F Persichetti, M Frontali, S Folstein, C Ross, M Franz, M Abbott. Nat Genet 1993
801
7

Huntington's disease: a clinical review.
Raymund A C Roos. Orphanet J Rare Dis 2010
391
7

Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease.
Elizabeth J Slow, Jeremy van Raamsdonk, Daniel Rogers, Sarah H Coleman, Rona K Graham, Yu Deng, Rosemary Oh, Nagat Bissada, Sazzad M Hossain, Yu-Zhou Yang,[...]. Hum Mol Genet 2003
556
7

Huntington disease in the South African population occurs on diverse and ethnically distinct genetic haplotypes.
Fiona K Baine, Chris Kay, Maria E Ketelaar, Jennifer A Collins, Alicia Semaka, Crystal N Doty, Amanda Krause, L Jacquie Greenberg, Michael R Hayden. Eur J Hum Genet 2013
35
20

A SNP in the HTT promoter alters NF-κB binding and is a bidirectional genetic modifier of Huntington disease.
Kristina Bečanović, Anne Nørremølle, Scott J Neal, Chris Kay, Jennifer A Collins, David Arenillas, Tobias Lilja, Giulia Gaudenzi, Shiana Manoharan, Crystal N Doty,[...]. Nat Neurosci 2015
57
12

Molecular mechanisms and potential therapeutical targets in Huntington's disease.
Chiara Zuccato, Marta Valenza, Elena Cattaneo. Physiol Rev 2010
544
7

The Biology of Huntingtin.
Frédéric Saudou, Sandrine Humbert. Neuron 2016
328
7


Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage.
Ulziibat Shirendeb, Arubala P Reddy, Maria Manczak, Marcus J Calkins, Peizhong Mao, Danilo A Tagle, P Hemachandra Reddy. Hum Mol Genet 2011
242
6

Predictors of phenotypic progression and disease onset in premanifest and early-stage Huntington's disease in the TRACK-HD study: analysis of 36-month observational data.
Sarah J Tabrizi, Rachael I Scahill, Gail Owen, Alexandra Durr, Blair R Leavitt, Raymund A Roos, Beth Borowsky, Bernhard Landwehrmeyer, Chris Frost, Hans Johnson,[...]. Lancet Neurol 2013
470
6

RNA interference improves motor and neuropathological abnormalities in a Huntington's disease mouse model.
Scott Q Harper, Patrick D Staber, Xiaohua He, Steven L Eliason, Inês H Martins, Qinwen Mao, Linda Yang, Robert M Kotin, Henry L Paulson, Beverly L Davidson. Proc Natl Acad Sci U S A 2005
488
6

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease.
Brinda Ravikumar, Coralie Vacher, Zdenek Berger, Janet E Davies, Shouqing Luo, Lourdes G Oroz, Francesco Scaravilli, Douglas F Easton, Rainer Duden, Cahir J O'Kane,[...]. Nat Genet 2004
6

Sustained effects of nonallele-specific Huntingtin silencing.
Valérie Drouet, Valérie Perrin, Raymonde Hassig, Noëlle Dufour, Gwennaelle Auregan, Sandro Alves, Gilles Bonvento, Emmanuel Brouillet, Ruth Luthi-Carter, Philippe Hantraye,[...]. Ann Neurol 2009
161
6

Mutant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro.
Eugenia Trushina, Roy B Dyer, John D Badger, Daren Ure, Lars Eide, David D Tran, Brent T Vrieze, Valerie Legendre-Guillemin, Peter S McPherson, Bhaskar S Mandavilli,[...]. Mol Cell Biol 2004
359
6

Huntington disease without CAG expansion: phenocopies or errors in assignment?
S E Andrew, Y P Goldberg, B Kremer, F Squitieri, J Theilmann, J Zeisler, H Telenius, S Adam, E Almquist, M Anvret. Am J Hum Genet 1994
85
7

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation.
S W Davies, M Turmaine, B A Cozens, M DiFiglia, A H Sharp, C A Ross, E Scherzinger, E E Wanker, L Mangiarini, G P Bates. Cell 1997
6

Huntingtin functions as a scaffold for selective macroautophagy.
Yan-Ning Rui, Zhen Xu, Bindi Patel, Zhihua Chen, Dongsheng Chen, Antonio Tito, Gabriela David, Yamin Sun, Erin F Stimming, Hugo J Bellen,[...]. Nat Cell Biol 2015
220
6

A new model for prediction of the age of onset and penetrance for Huntington's disease based on CAG length.
D R Langbehn, R R Brinkman, D Falush, J S Paulsen, M R Hayden. Clin Genet 2004
511
6



Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.