D Perregaux, C A Gabel. J Biol Chem 1994
Times Cited: 510
Times Cited: 510
Times Cited
Times Co-cited
Similarity
K⁺ efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter.
Raúl Muñoz-Planillo, Peter Kuffa, Giovanny Martínez-Colón, Brenna L Smith, Thekkelnaycke M Rajendiran, Gabriel Núñez. Immunity 2013
Raúl Muñoz-Planillo, Peter Kuffa, Giovanny Martínez-Colón, Brenna L Smith, Thekkelnaycke M Rajendiran, Gabriel Núñez. Immunity 2013
54
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
Jianjin Shi, Yue Zhao, Kun Wang, Xuyan Shi, Yue Wang, Huanwei Huang, Yinghua Zhuang, Tao Cai, Fengchao Wang, Feng Shao. Nature 2015
Jianjin Shi, Yue Zhao, Kun Wang, Xuyan Shi, Yue Wang, Huanwei Huang, Yinghua Zhuang, Tao Cai, Fengchao Wang, Feng Shao. Nature 2015
39
Cryopyrin activates the inflammasome in response to toxins and ATP.
Sanjeev Mariathasan, David S Weiss, Kim Newton, Jacqueline McBride, Karen O'Rourke, Meron Roose-Girma, Wyne P Lee, Yvette Weinrauch, Denise M Monack, Vishva M Dixit. Nature 2006
Sanjeev Mariathasan, David S Weiss, Kim Newton, Jacqueline McBride, Karen O'Rourke, Meron Roose-Girma, Wyne P Lee, Yvette Weinrauch, Denise M Monack, Vishva M Dixit. Nature 2006
37
Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration.
V Pétrilli, S Papin, C Dostert, A Mayor, F Martinon, J Tschopp. Cell Death Differ 2007
V Pétrilli, S Papin, C Dostert, A Mayor, F Martinon, J Tschopp. Cell Death Differ 2007
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The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta.
Fabio Martinon, Kimberly Burns, Jürg Tschopp. Mol Cell 2002
Fabio Martinon, Kimberly Burns, Jürg Tschopp. Mol Cell 2002
31
A role for mitochondria in NLRP3 inflammasome activation.
Rongbin Zhou, Amir S Yazdi, Philippe Menu, Jürg Tschopp. Nature 2011
Rongbin Zhou, Amir S Yazdi, Philippe Menu, Jürg Tschopp. Nature 2011
28
Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression.
Franz G Bauernfeind, Gabor Horvath, Andrea Stutz, Emad S Alnemri, Kelly MacDonald, David Speert, Teresa Fernandes-Alnemri, Jianghong Wu, Brian G Monks, Katherine A Fitzgerald,[...]. J Immunol 2009
Franz G Bauernfeind, Gabor Horvath, Andrea Stutz, Emad S Alnemri, Kelly MacDonald, David Speert, Teresa Fernandes-Alnemri, Jianghong Wu, Brian G Monks, Katherine A Fitzgerald,[...]. J Immunol 2009
27
Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling.
Nobuhiko Kayagaki, Irma B Stowe, Bettina L Lee, Karen O'Rourke, Keith Anderson, Søren Warming, Trinna Cuellar, Benjamin Haley, Merone Roose-Girma, Qui T Phung,[...]. Nature 2015
Nobuhiko Kayagaki, Irma B Stowe, Bettina L Lee, Karen O'Rourke, Keith Anderson, Søren Warming, Trinna Cuellar, Benjamin Haley, Merone Roose-Girma, Qui T Phung,[...]. Nature 2015
26
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization.
Veit Hornung, Franz Bauernfeind, Annett Halle, Eivind O Samstad, Hajime Kono, Kenneth L Rock, Katherine A Fitzgerald, Eicke Latz. Nat Immunol 2008
Veit Hornung, Franz Bauernfeind, Annett Halle, Eivind O Samstad, Hajime Kono, Kenneth L Rock, Katherine A Fitzgerald, Eicke Latz. Nat Immunol 2008
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Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion.
Wan-ting He, Haoqiang Wan, Lichen Hu, Pengda Chen, Xin Wang, Zhe Huang, Zhang-Hua Yang, Chuan-Qi Zhong, Jiahuai Han. Cell Res 2015
Wan-ting He, Haoqiang Wan, Lichen Hu, Pengda Chen, Xin Wang, Zhe Huang, Zhang-Hua Yang, Chuan-Qi Zhong, Jiahuai Han. Cell Res 2015
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Gout-associated uric acid crystals activate the NALP3 inflammasome.
Fabio Martinon, Virginie Pétrilli, Annick Mayor, Aubry Tardivel, Jürg Tschopp. Nature 2006
Fabio Martinon, Virginie Pétrilli, Annick Mayor, Aubry Tardivel, Jürg Tschopp. Nature 2006
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Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores.
Xing Liu, Zhibin Zhang, Jianbin Ruan, Youdong Pan, Venkat Giri Magupalli, Hao Wu, Judy Lieberman. Nature 2016
Xing Liu, Zhibin Zhang, Jianbin Ruan, Youdong Pan, Venkat Giri Magupalli, Hao Wu, Judy Lieberman. Nature 2016
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A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.
Rebecca C Coll, Avril A B Robertson, Jae Jin Chae, Sarah C Higgins, Raúl Muñoz-Planillo, Marco C Inserra, Irina Vetter, Lara S Dungan, Brian G Monks, Andrea Stutz,[...]. Nat Med 2015
Rebecca C Coll, Avril A B Robertson, Jae Jin Chae, Sarah C Higgins, Raúl Muñoz-Planillo, Marco C Inserra, Irina Vetter, Lara S Dungan, Brian G Monks, Andrea Stutz,[...]. Nat Med 2015
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Non-canonical inflammasome activation targets caspase-11.
Nobuhiko Kayagaki, Søren Warming, Mohamed Lamkanfi, Lieselotte Vande Walle, Salina Louie, Jennifer Dong, Kim Newton, Yan Qu, Jinfeng Liu, Sherry Heldens,[...]. Nature 2011
Nobuhiko Kayagaki, Søren Warming, Mohamed Lamkanfi, Lieselotte Vande Walle, Salina Louie, Jennifer Dong, Kim Newton, Yan Qu, Jinfeng Liu, Sherry Heldens,[...]. Nature 2011
21
Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis.
Kenichi Shimada, Timothy R Crother, Justin Karlin, Jargalsaikhan Dagvadorj, Norika Chiba, Shuang Chen, V Krishnan Ramanujan, Andrea J Wolf, Laurent Vergnes, David M Ojcius,[...]. Immunity 2012
Kenichi Shimada, Timothy R Crother, Justin Karlin, Jargalsaikhan Dagvadorj, Norika Chiba, Shuang Chen, V Krishnan Ramanujan, Andrea J Wolf, Laurent Vergnes, David M Ojcius,[...]. Immunity 2012
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The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP.
Geun-Shik Lee, Naeha Subramanian, Andrew I Kim, Ivona Aksentijevich, Raphaela Goldbach-Mansky, David B Sacks, Ronald N Germain, Daniel L Kastner, Jae Jin Chae. Nature 2012
Geun-Shik Lee, Naeha Subramanian, Andrew I Kim, Ivona Aksentijevich, Raphaela Goldbach-Mansky, David B Sacks, Ronald N Germain, Daniel L Kastner, Jae Jin Chae. Nature 2012
20
Critical role for calcium mobilization in activation of the NLRP3 inflammasome.
Tomohiko Murakami, Johan Ockinger, Jiujiu Yu, Vanessa Byles, Aisleen McColl, Aldebaran M Hofer, Tiffany Horng. Proc Natl Acad Sci U S A 2012
Tomohiko Murakami, Johan Ockinger, Jiujiu Yu, Vanessa Byles, Aisleen McColl, Aldebaran M Hofer, Tiffany Horng. Proc Natl Acad Sci U S A 2012
20
K+ efflux agonists induce NLRP3 inflammasome activation independently of Ca2+ signaling.
Michael A Katsnelson, L Graham Rucker, Hana M Russo, George R Dubyak. J Immunol 2015
Michael A Katsnelson, L Graham Rucker, Hana M Russo, George R Dubyak. J Immunol 2015
19
Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes.
Alvin Lu, Venkat Giri Magupalli, Jianbin Ruan, Qian Yin, Maninjay K Atianand, Matthijn R Vos, Gunnar F Schröder, Katherine A Fitzgerald, Hao Wu, Edward H Egelman. Cell 2014
Alvin Lu, Venkat Giri Magupalli, Jianbin Ruan, Qian Yin, Maninjay K Atianand, Matthijn R Vos, Gunnar F Schröder, Katherine A Fitzgerald, Hao Wu, Edward H Egelman. Cell 2014
19
K+ Efflux-Independent NLRP3 Inflammasome Activation by Small Molecules Targeting Mitochondria.
Christina J Groß, Ritu Mishra, Katharina S Schneider, Guillaume Médard, Jennifer Wettmarshausen, Daniela C Dittlein, Hexin Shi, Oliver Gorka, Paul-Albert Koenig, Stephan Fromm,[...]. Immunity 2016
Christina J Groß, Ritu Mishra, Katharina S Schneider, Guillaume Médard, Jennifer Wettmarshausen, Daniela C Dittlein, Hexin Shi, Oliver Gorka, Paul-Albert Koenig, Stephan Fromm,[...]. Immunity 2016
19
NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux.
Yuan He, Melody Y Zeng, Dahai Yang, Benny Motro, Gabriel Núñez. Nature 2016
Yuan He, Melody Y Zeng, Dahai Yang, Benny Motro, Gabriel Núñez. Nature 2016
19
NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component.
Hexin Shi, Ying Wang, Xiaohong Li, Xiaoming Zhan, Miao Tang, Maggy Fina, Lijing Su, David Pratt, Chun Hui Bu, Sara Hildebrand,[...]. Nat Immunol 2016
Hexin Shi, Ying Wang, Xiaohong Li, Xiaoming Zhan, Miao Tang, Maggy Fina, Lijing Su, David Pratt, Chun Hui Bu, Sara Hildebrand,[...]. Nat Immunol 2016
18
The NALP3 inflammasome is involved in the innate immune response to amyloid-beta.
Annett Halle, Veit Hornung, Gabor C Petzold, Cameron R Stewart, Brian G Monks, Thomas Reinheckel, Katherine A Fitzgerald, Eicke Latz, Kathryn J Moore, Douglas T Golenbock. Nat Immunol 2008
Annett Halle, Veit Hornung, Gabor C Petzold, Cameron R Stewart, Brian G Monks, Thomas Reinheckel, Katherine A Fitzgerald, Eicke Latz, Kathryn J Moore, Douglas T Golenbock. Nat Immunol 2008
18
Mitochondrial cardiolipin is required for Nlrp3 inflammasome activation.
Shankar S Iyer, Qiong He, John R Janczy, Eric I Elliott, Zhenyu Zhong, Alicia K Olivier, Jeffrey J Sadler, Vickie Knepper-Adrian, Renzhi Han, Liang Qiao,[...]. Immunity 2013
Shankar S Iyer, Qiong He, John R Janczy, Eric I Elliott, Zhenyu Zhong, Alicia K Olivier, Jeffrey J Sadler, Vickie Knepper-Adrian, Renzhi Han, Liang Qiao,[...]. Immunity 2013
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Inflammatory caspases are innate immune receptors for intracellular LPS.
Jianjin Shi, Yue Zhao, Yupeng Wang, Wenqing Gao, Jingjin Ding, Peng Li, Liyan Hu, Feng Shao. Nature 2014
Jianjin Shi, Yue Zhao, Yupeng Wang, Wenqing Gao, Jingjin Ding, Peng Li, Liyan Hu, Feng Shao. Nature 2014
18
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals.
Peter Duewell, Hajime Kono, Katey J Rayner, Cherilyn M Sirois, Gregory Vladimer, Franz G Bauernfeind, George S Abela, Luigi Franchi, Gabriel Nuñez, Max Schnurr,[...]. Nature 2010
Peter Duewell, Hajime Kono, Katey J Rayner, Cherilyn M Sirois, Gregory Vladimer, Franz G Bauernfeind, George S Abela, Luigi Franchi, Gabriel Nuñez, Max Schnurr,[...]. Nature 2010
17
Human Monocytes Engage an Alternative Inflammasome Pathway.
Moritz M Gaidt, Thomas S Ebert, Dhruv Chauhan, Tobias Schmidt, Jonathan L Schmid-Burgk, Francesca Rapino, Avril A B Robertson, Matthew A Cooper, Thomas Graf, Veit Hornung. Immunity 2016
Moritz M Gaidt, Thomas S Ebert, Dhruv Chauhan, Tobias Schmidt, Jonathan L Schmid-Burgk, Francesca Rapino, Avril A B Robertson, Matthew A Cooper, Thomas Graf, Veit Hornung. Immunity 2016
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Noncanonical inflammasome activation by intracellular LPS independent of TLR4.
Nobuhiko Kayagaki, Michael T Wong, Irma B Stowe, Sree Ranjani Ramani, Lino C Gonzalez, Sachiko Akashi-Takamura, Kensuke Miyake, Juan Zhang, Wyne P Lee, Artur Muszyński,[...]. Science 2013
Nobuhiko Kayagaki, Michael T Wong, Irma B Stowe, Sree Ranjani Ramani, Lino C Gonzalez, Sachiko Akashi-Takamura, Kensuke Miyake, Juan Zhang, Wyne P Lee, Artur Muszyński,[...]. Science 2013
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The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7).
A Surprenant, F Rassendren, E Kawashima, R A North, G Buell. Science 1996
A Surprenant, F Rassendren, E Kawashima, R A North, G Buell. Science 1996
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Pore-forming activity and structural autoinhibition of the gasdermin family.
Jingjin Ding, Kun Wang, Wang Liu, Yang She, Qi Sun, Jianjin Shi, Hanzi Sun, Da-Cheng Wang, Feng Shao. Nature 2016
Jingjin Ding, Kun Wang, Wang Liu, Yang She, Qi Sun, Jianjin Shi, Hanzi Sun, Da-Cheng Wang, Feng Shao. Nature 2016
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Inflammasomes: mechanism of assembly, regulation and signalling.
Petr Broz, Vishva M Dixit. Nat Rev Immunol 2016
Petr Broz, Vishva M Dixit. Nat Rev Immunol 2016
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CLICs-dependent chloride efflux is an essential and proximal upstream event for NLRP3 inflammasome activation.
Tiantian Tang, Xueting Lang, Congfei Xu, Xiaqiong Wang, Tao Gong, Yanqing Yang, Jun Cui, Li Bai, Jun Wang, Wei Jiang,[...]. Nat Commun 2017
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The Pore-Forming Protein Gasdermin D Regulates Interleukin-1 Secretion from Living Macrophages.
Charles L Evavold, Jianbin Ruan, Yunhao Tan, Shiyu Xia, Hao Wu, Jonathan C Kagan. Immunity 2018
Charles L Evavold, Jianbin Ruan, Yunhao Tan, Shiyu Xia, Hao Wu, Jonathan C Kagan. Immunity 2018
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Non-transcriptional priming and deubiquitination regulate NLRP3 inflammasome activation.
Christine Juliana, Teresa Fernandes-Alnemri, Seokwon Kang, Andrew Farias, Fengsong Qin, Emad S Alnemri. J Biol Chem 2012
Christine Juliana, Teresa Fernandes-Alnemri, Seokwon Kang, Andrew Farias, Fengsong Qin, Emad S Alnemri. J Biol Chem 2012
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Thioredoxin-interacting protein links oxidative stress to inflammasome activation.
Rongbin Zhou, Aubry Tardivel, Bernard Thorens, Inpyo Choi, Jürg Tschopp. Nat Immunol 2010
Rongbin Zhou, Aubry Tardivel, Bernard Thorens, Inpyo Choi, Jürg Tschopp. Nat Immunol 2010
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Deubiquitination of NLRP3 by BRCC3 critically regulates inflammasome activity.
Bénédicte F Py, Mi-Sung Kim, Helin Vakifahmetoglu-Norberg, Junying Yuan. Mol Cell 2013
Bénédicte F Py, Mi-Sung Kim, Helin Vakifahmetoglu-Norberg, Junying Yuan. Mol Cell 2013
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Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica.
Catherine Dostert, Virginie Pétrilli, Robin Van Bruggen, Chad Steele, Brooke T Mossman, Jürg Tschopp. Science 2008
Catherine Dostert, Virginie Pétrilli, Robin Van Bruggen, Chad Steele, Brooke T Mossman, Jürg Tschopp. Science 2008
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14
Inflammasomes: mechanism of action, role in disease, and therapeutics.
Haitao Guo, Justin B Callaway, Jenny P-Y Ting. Nat Med 2015
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Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome.
Kiichi Nakahira, Jeffrey Adam Haspel, Vijay A K Rathinam, Seon-Jin Lee, Tamas Dolinay, Hilaire C Lam, Joshua A Englert, Marlene Rabinovitch, Manuela Cernadas, Hong Pyo Kim,[...]. Nat Immunol 2011
Kiichi Nakahira, Jeffrey Adam Haspel, Vijay A K Rathinam, Seon-Jin Lee, Tamas Dolinay, Hilaire C Lam, Joshua A Englert, Marlene Rabinovitch, Manuela Cernadas, Hong Pyo Kim,[...]. Nat Immunol 2011
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The adaptor MAVS promotes NLRP3 mitochondrial localization and inflammasome activation.
Naeha Subramanian, Kannan Natarajan, Menna R Clatworthy, Ze Wang, Ronald N Germain. Cell 2013
Naeha Subramanian, Kannan Natarajan, Menna R Clatworthy, Ze Wang, Ronald N Germain. Cell 2013
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Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATP-gated P2X7 receptor.
Pablo Pelegrin, Annmarie Surprenant. EMBO J 2006
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Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf.
Sanjeev Mariathasan, Kim Newton, Denise M Monack, Domagoj Vucic, Dorothy M French, Wyne P Lee, Meron Roose-Girma, Sharon Erickson, Vishva M Dixit. Nature 2004
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Mechanism and Regulation of NLRP3 Inflammasome Activation.
Yuan He, Hideki Hara, Gabriel Núñez. Trends Biochem Sci 2016
Yuan He, Hideki Hara, Gabriel Núñez. Trends Biochem Sci 2016
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Activation and regulation of the inflammasomes.
Eicke Latz, T Sam Xiao, Andrea Stutz. Nat Rev Immunol 2013
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GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranes.
Robin A Aglietti, Alberto Estevez, Aaron Gupta, Monica Gonzalez Ramirez, Peter S Liu, Nobuhiko Kayagaki, Claudio Ciferri, Vishva M Dixit, Erin C Dueber. Proc Natl Acad Sci U S A 2016
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Prion-like polymerization underlies signal transduction in antiviral immune defense and inflammasome activation.
Xin Cai, Jueqi Chen, Hui Xu, Siqi Liu, Qiu-Xing Jiang, Randal Halfmann, Zhijian J Chen. Cell 2014
Xin Cai, Jueqi Chen, Hui Xu, Siqi Liu, Qiu-Xing Jiang, Randal Halfmann, Zhijian J Chen. Cell 2014
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Caspase-11 Requires the Pannexin-1 Channel and the Purinergic P2X7 Pore to Mediate Pyroptosis and Endotoxic Shock.
Dahai Yang, Yuan He, Raul Muñoz-Planillo, Qin Liu, Gabriel Núñez. Immunity 2015
Dahai Yang, Yuan He, Raul Muñoz-Planillo, Qin Liu, Gabriel Núñez. Immunity 2015
12
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.