M E Gurney, H Pu, A Y Chiu, M C Dal Canto, C Y Polchow, D D Alexander, J Caliendo, A Hentati, Y W Kwon, H X Deng. Science 1994
Times Cited: 3223
Times Cited: 3223
Times Cited
Times Co-cited
Similarity
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis.
D R Rosen, T Siddique, D Patterson, D A Figlewicz, P Sapp, A Hentati, D Donaldson, J Goto, J P O'Regan, H X Deng. Nature 1993
D R Rosen, T Siddique, D Patterson, D A Figlewicz, P Sapp, A Hentati, D Donaldson, J Goto, J P O'Regan, H X Deng. Nature 1993
36
ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions.
L I Bruijn, M W Becher, M K Lee, K L Anderson, N A Jenkins, N G Copeland, S S Sisodia, J D Rothstein, D R Borchelt, D L Price,[...]. Neuron 1997
L I Bruijn, M W Becher, M K Lee, K L Anderson, N A Jenkins, N G Copeland, S S Sisodia, J D Rothstein, D R Borchelt, D L Price,[...]. Neuron 1997
17
Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS.
Mariely DeJesus-Hernandez, Ian R Mackenzie, Bradley F Boeve, Adam L Boxer, Matt Baker, Nicola J Rutherford, Alexandra M Nicholson, NiCole A Finch, Heather Flynn, Jennifer Adamson,[...]. Neuron 2011
Mariely DeJesus-Hernandez, Ian R Mackenzie, Bradley F Boeve, Adam L Boxer, Matt Baker, Nicola J Rutherford, Alexandra M Nicholson, NiCole A Finch, Heather Flynn, Jennifer Adamson,[...]. Neuron 2011
16
16
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
Manuela Neumann, Deepak M Sampathu, Linda K Kwong, Adam C Truax, Matthew C Micsenyi, Thomas T Chou, Jennifer Bruce, Theresa Schuck, Murray Grossman, Christopher M Clark,[...]. Science 2006
Manuela Neumann, Deepak M Sampathu, Linda K Kwong, Adam C Truax, Matthew C Micsenyi, Thomas T Chou, Jennifer Bruce, Theresa Schuck, Murray Grossman, Christopher M Clark,[...]. Science 2006
13
Onset and progression in inherited ALS determined by motor neurons and microglia.
Séverine Boillée, Koji Yamanaka, Christian S Lobsiger, Neal G Copeland, Nancy A Jenkins, George Kassiotis, George Kollias, Don W Cleveland. Science 2006
Séverine Boillée, Koji Yamanaka, Christian S Lobsiger, Neal G Copeland, Nancy A Jenkins, George Kassiotis, George Kollias, Don W Cleveland. Science 2006
13
State of play in amyotrophic lateral sclerosis genetics.
Alan E Renton, Adriano Chiò, Bryan J Traynor. Nat Neurosci 2014
Alan E Renton, Adriano Chiò, Bryan J Traynor. Nat Neurosci 2014
12
Amyotrophic lateral sclerosis.
Orla Hardiman, Ammar Al-Chalabi, Adriano Chio, Emma M Corr, Giancarlo Logroscino, Wim Robberecht, Pamela J Shaw, Zachary Simmons, Leonard H van den Berg. Nat Rev Dis Primers 2017
Orla Hardiman, Ammar Al-Chalabi, Adriano Chio, Emma M Corr, Giancarlo Logroscino, Wim Robberecht, Pamela J Shaw, Zachary Simmons, Leonard H van den Berg. Nat Rev Dis Primers 2017
12
Amyotrophic lateral sclerosis is a distal axonopathy: evidence in mice and man.
Lindsey R Fischer, Deborah G Culver, Philip Tennant, Albert A Davis, Minsheng Wang, Amilcar Castellano-Sanchez, Jaffar Khan, Meraida A Polak, Jonathan D Glass. Exp Neurol 2004
Lindsey R Fischer, Deborah G Culver, Philip Tennant, Albert A Davis, Minsheng Wang, Amilcar Castellano-Sanchez, Jaffar Khan, Meraida A Polak, Jonathan D Glass. Exp Neurol 2004
11
ALS: a disease of motor neurons and their nonneuronal neighbors.
Séverine Boillée, Christine Vande Velde, Don W Cleveland. Neuron 2006
Séverine Boillée, Christine Vande Velde, Don W Cleveland. Neuron 2006
10
Time course of preferential motor unit loss in the SOD1 G93A mouse model of amyotrophic lateral sclerosis.
J Hegedus, C T Putman, T Gordon. Neurobiol Dis 2007
J Hegedus, C T Putman, T Gordon. Neurobiol Dis 2007
10
Amyotrophic lateral sclerosis.
Matthew C Kiernan, Steve Vucic, Benjamin C Cheah, Martin R Turner, Andrew Eisen, Orla Hardiman, James R Burrell, Margaret C Zoing. Lancet 2011
Matthew C Kiernan, Steve Vucic, Benjamin C Cheah, Martin R Turner, Andrew Eisen, Orla Hardiman, James R Burrell, Margaret C Zoing. Lancet 2011
10
Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6.
Caroline Vance, Boris Rogelj, Tibor Hortobágyi, Kurt J De Vos, Agnes Lumi Nishimura, Jemeen Sreedharan, Xun Hu, Bradley Smith, Deborah Ruddy, Paul Wright,[...]. Science 2009
Caroline Vance, Boris Rogelj, Tibor Hortobágyi, Kurt J De Vos, Agnes Lumi Nishimura, Jemeen Sreedharan, Xun Hu, Bradley Smith, Deborah Ruddy, Paul Wright,[...]. Science 2009
9
An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria.
P C Wong, C A Pardo, D R Borchelt, M K Lee, N G Copeland, N A Jenkins, S S Sisodia, D W Cleveland, D L Price. Neuron 1995
P C Wong, C A Pardo, D R Borchelt, M K Lee, N G Copeland, N A Jenkins, S S Sisodia, D W Cleveland, D L Price. Neuron 1995
9
Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury.
A G Reaume, J L Elliott, E K Hoffman, N W Kowall, R J Ferrante, D F Siwek, H M Wilcox, D G Flood, M F Beal, R H Brown,[...]. Nat Genet 1996
A G Reaume, J L Elliott, E K Hoffman, N W Kowall, R J Ferrante, D F Siwek, H M Wilcox, D G Flood, M F Beal, R H Brown,[...]. Nat Genet 1996
9
A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD.
Alan E Renton, Elisa Majounie, Adrian Waite, Javier Simón-Sánchez, Sara Rollinson, J Raphael Gibbs, Jennifer C Schymick, Hannu Laaksovirta, John C van Swieten, Liisa Myllykangas,[...]. Neuron 2011
Alan E Renton, Elisa Majounie, Adrian Waite, Javier Simón-Sánchez, Sara Rollinson, J Raphael Gibbs, Jennifer C Schymick, Hannu Laaksovirta, John C van Swieten, Liisa Myllykangas,[...]. Neuron 2011
9
Selective vulnerability and pruning of phasic motoneuron axons in motoneuron disease alleviated by CNTF.
San Pun, Alexandre Ferrão Santos, Smita Saxena, Lan Xu, Pico Caroni. Nat Neurosci 2006
San Pun, Alexandre Ferrão Santos, Smita Saxena, Lan Xu, Pico Caroni. Nat Neurosci 2006
9
Age-dependent penetrance of disease in a transgenic mouse model of familial amyotrophic lateral sclerosis.
A Y Chiu, P Zhai, M C Dal Canto, T M Peters, Y W Kwon, S M Prattis, M E Gurney. Mol Cell Neurosci 1995
A Y Chiu, P Zhai, M C Dal Canto, T M Peters, Y W Kwon, S M Prattis, M E Gurney. Mol Cell Neurosci 1995
9
Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase.
H X Deng, A Hentati, J A Tainer, Z Iqbal, A Cayabyab, W Y Hung, E D Getzoff, P Hu, B Herzfeldt, R P Roos. Science 1993
H X Deng, A Hentati, J A Tainer, Z Iqbal, A Cayabyab, W Y Hung, E D Getzoff, P Hu, B Herzfeldt, R P Roos. Science 1993
9
Phase 1-2 Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS.
Timothy Miller, Merit Cudkowicz, Pamela J Shaw, Peter M Andersen, Nazem Atassi, Robert C Bucelli, Angela Genge, Jonathan Glass, Shafeeq Ladha, Albert L Ludolph,[...]. N Engl J Med 2020
Timothy Miller, Merit Cudkowicz, Pamela J Shaw, Peter M Andersen, Nazem Atassi, Robert C Bucelli, Angela Genge, Jonathan Glass, Shafeeq Ladha, Albert L Ludolph,[...]. N Engl J Med 2020
9
Rodent Models of Amyotrophic Lateral Sclerosis.
Thomas Philips, Jeffrey D Rothstein. Curr Protoc Pharmacol 2015
Thomas Philips, Jeffrey D Rothstein. Curr Protoc Pharmacol 2015
8
Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis.
T J Kwiatkowski, D A Bosco, A L Leclerc, E Tamrazian, C R Vanderburg, C Russ, A Davis, J Gilchrist, E J Kasarskis, T Munsat,[...]. Science 2009
T J Kwiatkowski, D A Bosco, A L Leclerc, E Tamrazian, C R Vanderburg, C Russ, A Davis, J Gilchrist, E J Kasarskis, T Munsat,[...]. Science 2009
8
Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS.
Daryl A Bosco, Gerardo Morfini, N Murat Karabacak, Yuyu Song, Francois Gros-Louis, Piera Pasinelli, Holly Goolsby, Benjamin A Fontaine, Nathan Lemay, Diane McKenna-Yasek,[...]. Nat Neurosci 2010
Daryl A Bosco, Gerardo Morfini, N Murat Karabacak, Yuyu Song, Francois Gros-Louis, Piera Pasinelli, Holly Goolsby, Benjamin A Fontaine, Nathan Lemay, Diane McKenna-Yasek,[...]. Nat Neurosci 2010
8
Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis.
Koji Yamanaka, Seung Joo Chun, Severine Boillee, Noriko Fujimori-Tonou, Hirofumi Yamashita, David H Gutmann, Ryosuke Takahashi, Hidemi Misawa, Don W Cleveland. Nat Neurosci 2008
Koji Yamanaka, Seung Joo Chun, Severine Boillee, Noriko Fujimori-Tonou, Hirofumi Yamashita, David H Gutmann, Ryosuke Takahashi, Hidemi Misawa, Don W Cleveland. Nat Neurosci 2008
8
TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration.
Iga Wegorzewska, Shaughn Bell, Nigel J Cairns, Timothy M Miller, Robert H Baloh. Proc Natl Acad Sci U S A 2009
Iga Wegorzewska, Shaughn Bell, Nigel J Cairns, Timothy M Miller, Robert H Baloh. Proc Natl Acad Sci U S A 2009
8
Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice.
A M Clement, M D Nguyen, E A Roberts, M L Garcia, S Boillée, M Rule, A P McMahon, W Doucette, D Siwek, R J Ferrante,[...]. Science 2003
A M Clement, M D Nguyen, E A Roberts, M L Garcia, S Boillée, M Rule, A P McMahon, W Doucette, D Siwek, R J Ferrante,[...]. Science 2003
7
Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis.
M E Ripps, G W Huntley, P R Hof, J H Morrison, J W Gordon. Proc Natl Acad Sci U S A 1995
M E Ripps, G W Huntley, P R Hof, J H Morrison, J W Gordon. Proc Natl Acad Sci U S A 1995
7
Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis.
David R Beers, Jenny S Henkel, Qin Xiao, Weihua Zhao, Jinghong Wang, Albert A Yen, Laszlo Siklos, Scott R McKercher, Stanley H Appel. Proc Natl Acad Sci U S A 2006
David R Beers, Jenny S Henkel, Qin Xiao, Weihua Zhao, Jinghong Wang, Albert A Yen, Laszlo Siklos, Scott R McKercher, Stanley H Appel. Proc Natl Acad Sci U S A 2006
7
A comprehensive review of amyotrophic lateral sclerosis.
Sara Zarei, Karen Carr, Luz Reiley, Kelvin Diaz, Orleiquis Guerra, Pablo Fernandez Altamirano, Wilfredo Pagani, Daud Lodin, Gloria Orozco, Angel Chinea. Surg Neurol Int 2015
Sara Zarei, Karen Carr, Luz Reiley, Kelvin Diaz, Orleiquis Guerra, Pablo Fernandez Altamirano, Wilfredo Pagani, Daud Lodin, Gloria Orozco, Angel Chinea. Surg Neurol Int 2015
7
ALS Clinical Trials Review: 20 Years of Failure. Are We Any Closer to Registering a New Treatment?
Dmitry Petrov, Colin Mansfield, Alain Moussy, Olivier Hermine. Front Aging Neurosci 2017
Dmitry Petrov, Colin Mansfield, Alain Moussy, Olivier Hermine. Front Aging Neurosci 2017
7
Mutant SOD1 mediated pathogenesis of Amyotrophic Lateral Sclerosis.
Simran J Kaur, Stephanie R McKeown, Shazia Rashid. Gene 2016
Simran J Kaur, Stephanie R McKeown, Shazia Rashid. Gene 2016
7
Riluzole and edaravone: A tale of two amyotrophic lateral sclerosis drugs.
Manoj Kumar Jaiswal. Med Res Rev 2019
Manoj Kumar Jaiswal. Med Res Rev 2019
7
Axonal degeneration, distal collateral branching and neuromuscular junction architecture alterations occur prior to symptom onset in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis.
Jayden A Clark, Katherine A Southam, Catherine A Blizzard, Anna E King, Tracey C Dickson. J Chem Neuroanat 2016
Jayden A Clark, Katherine A Southam, Catherine A Blizzard, Anna E King, Tracey C Dickson. J Chem Neuroanat 2016
14
Neuroinflammation in amyotrophic lateral sclerosis: role of glial activation in motor neuron disease.
Thomas Philips, Wim Robberecht. Lancet Neurol 2011
Thomas Philips, Wim Robberecht. Lancet Neurol 2011
7
Non-cell autonomous toxicity in neurodegenerative disorders: ALS and beyond.
Hristelina Ilieva, Magdalini Polymenidou, Don W Cleveland. J Cell Biol 2009
Hristelina Ilieva, Magdalini Polymenidou, Don W Cleveland. J Cell Biol 2009
7
TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis.
Jemeen Sreedharan, Ian P Blair, Vineeta B Tripathi, Xun Hu, Caroline Vance, Boris Rogelj, Steven Ackerley, Jennifer C Durnall, Kelly L Williams, Emanuele Buratti,[...]. Science 2008
Jemeen Sreedharan, Ian P Blair, Vineeta B Tripathi, Xun Hu, Caroline Vance, Boris Rogelj, Steven Ackerley, Jennifer C Durnall, Kelly L Williams, Emanuele Buratti,[...]. Science 2008
7
ALS as a distal axonopathy: molecular mechanisms affecting neuromuscular junction stability in the presymptomatic stages of the disease.
Elizabeth B Moloney, Fred de Winter, Joost Verhaagen. Front Neurosci 2014
Elizabeth B Moloney, Fred de Winter, Joost Verhaagen. Front Neurosci 2014
7
Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons.
Makiko Nagai, Diane B Re, Tetsuya Nagata, Alcmène Chalazonitis, Thomas M Jessell, Hynek Wichterle, Serge Przedborski. Nat Neurosci 2007
Makiko Nagai, Diane B Re, Tetsuya Nagata, Alcmène Chalazonitis, Thomas M Jessell, Hynek Wichterle, Serge Przedborski. Nat Neurosci 2007
7
Molecular pathways of motor neuron injury in amyotrophic lateral sclerosis.
Laura Ferraiuolo, Janine Kirby, Andrew J Grierson, Michael Sendtner, Pamela J Shaw. Nat Rev Neurol 2011
Laura Ferraiuolo, Janine Kirby, Andrew J Grierson, Michael Sendtner, Pamela J Shaw. Nat Rev Neurol 2011
6
Intercellular propagated misfolding of wild-type Cu/Zn superoxide dismutase occurs via exosome-dependent and -independent mechanisms.
Leslie I Grad, Justin J Yerbury, Bradley J Turner, William C Guest, Edward Pokrishevsky, Megan A O'Neill, Anat Yanai, Judith M Silverman, Rafaa Zeineddine, Lisa Corcoran,[...]. Proc Natl Acad Sci U S A 2014
Leslie I Grad, Justin J Yerbury, Bradley J Turner, William C Guest, Edward Pokrishevsky, Megan A O'Neill, Anat Yanai, Judith M Silverman, Rafaa Zeineddine, Lisa Corcoran,[...]. Proc Natl Acad Sci U S A 2014
6
Copper-zinc superoxide dismutase and amyotrophic lateral sclerosis.
Joan Selverstone Valentine, Peter A Doucette, Soshanna Zittin Potter. Annu Rev Biochem 2005
Joan Selverstone Valentine, Peter A Doucette, Soshanna Zittin Potter. Annu Rev Biochem 2005
6
Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions.
P H Tu, P Raju, K A Robinson, M E Gurney, J Q Trojanowski, V M Lee. Proc Natl Acad Sci U S A 1996
P H Tu, P Raju, K A Robinson, M E Gurney, J Q Trojanowski, V M Lee. Proc Natl Acad Sci U S A 1996
6
Current hypotheses for the underlying biology of amyotrophic lateral sclerosis.
Jeffrey D Rothstein. Ann Neurol 2009
Jeffrey D Rothstein. Ann Neurol 2009
6
Preferential motor unit loss in the SOD1 G93A transgenic mouse model of amyotrophic lateral sclerosis.
J Hegedus, C T Putman, N Tyreman, T Gordon. J Physiol 2008
J Hegedus, C T Putman, N Tyreman, T Gordon. J Physiol 2008
6
The "dying-back" phenomenon of motor neurons in ALS.
Michal Dadon-Nachum, Eldad Melamed, Daniel Offen. J Mol Neurosci 2011
Michal Dadon-Nachum, Eldad Melamed, Daniel Offen. J Mol Neurosci 2011
6
Amyotrophic lateral sclerosis.
Michael A van Es, Orla Hardiman, Adriano Chio, Ammar Al-Chalabi, R Jeroen Pasterkamp, Jan H Veldink, Leonard H van den Berg. Lancet 2017
Michael A van Es, Orla Hardiman, Adriano Chio, Ammar Al-Chalabi, R Jeroen Pasterkamp, Jan H Veldink, Leonard H van den Berg. Lancet 2017
6
Modeling sporadic ALS in iPSC-derived motor neurons identifies a potential therapeutic agent.
Koki Fujimori, Mitsuru Ishikawa, Asako Otomo, Naoki Atsuta, Ryoichi Nakamura, Tetsuya Akiyama, Shinji Hadano, Masashi Aoki, Hideyuki Saya, Gen Sobue,[...]. Nat Med 2018
Koki Fujimori, Mitsuru Ishikawa, Asako Otomo, Naoki Atsuta, Ryoichi Nakamura, Tetsuya Akiyama, Shinji Hadano, Masashi Aoki, Hideyuki Saya, Gen Sobue,[...]. Nat Med 2018
6
Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations.
Ian R A Mackenzie, Eileen H Bigio, Paul G Ince, Felix Geser, Manuela Neumann, Nigel J Cairns, Linda K Kwong, Mark S Forman, John Ravits, Heather Stewart,[...]. Ann Neurol 2007
Ian R A Mackenzie, Eileen H Bigio, Paul G Ince, Felix Geser, Manuela Neumann, Nigel J Cairns, Linda K Kwong, Mark S Forman, John Ravits, Heather Stewart,[...]. Ann Neurol 2007
6
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.