A citation-based method for searching scientific literature

C Kenyon, J Chang, E Gensch, A Rudner, R Tabtiang. Nature 1993
Times Cited: 2184







List of co-cited articles
1102 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


The genetics of ageing.
Cynthia J Kenyon. Nature 2010
25

The hallmarks of aging.
Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013
23


Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans.
Coleen T Murphy, Steven A McCarroll, Cornelia I Bargmann, Andrew Fraser, Ravi S Kamath, Julie Ahringer, Hao Li, Cynthia Kenyon. Nature 2003
19

Extending healthy life span--from yeast to humans.
Luigi Fontana, Linda Partridge, Valter D Longo. Science 2010
14

The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans.
S Ogg, S Paradis, S Gottlieb, G I Patterson, L Lee, H A Tissenbaum, G Ruvkun. Nature 1997
14


Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein.
D J Clancy, D Gems, L G Harshman, S Oldham, H Stocker, E Hafen, S J Leevers, L Partridge. Science 2001
974
13

Tissue-specific activities of C. elegans DAF-16 in the regulation of lifespan.
Nataliya Libina, Jennifer R Berman, Cynthia Kenyon. Cell 2003
530
12




IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice.
Martin Holzenberger, Joëlle Dupont, Bertrand Ducos, Patricia Leneuve, Alain Géloën, Patrick C Even, Pascale Cervera, Yves Le Bouc. Nature 2003
11

Regulation of aging and age-related disease by DAF-16 and heat-shock factor.
Ao-Lin Hsu, Coleen T Murphy, Cynthia Kenyon. Science 2003
971
11

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice.
David E Harrison, Randy Strong, Zelton Dave Sharp, James F Nelson, Clinton M Astle, Kevin Flurkey, Nancy L Nadon, J Erby Wilkinson, Krystyna Frenkel, Christy S Carter,[...]. Nature 2009
10

Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans.
Jennifer M A Tullet, Maren Hertweck, Jae Hyung An, Joseph Baker, Ji Yun Hwang, Shu Liu, Riva P Oliveira, Ralf Baumeister, T Keith Blackwell. Cell 2008
550
10

Long live FOXO: unraveling the role of FOXO proteins in aging and longevity.
Rute Martins, Gordon J Lithgow, Wolfgang Link. Aging Cell 2016
295
10

Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body.
Dae Sung Hwangbo, Boris Gershman, Meng-Ping Tu, Michael Palmer, Marc Tatar. Nature 2004
640
9

Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans.
Malene Hansen, Stefan Taubert, Douglas Crawford, Nataliya Libina, Seung-Jae Lee, Cynthia Kenyon. Aging Cell 2007
551
9

SKN-1/Nrf, stress responses, and aging in Caenorhabditis elegans.
T Keith Blackwell, Michael J Steinbaugh, John M Hourihan, Collin Y Ewald, Meltem Isik. Free Radic Biol Med 2015
214
9

A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function.
M Tatar, A Kopelman, D Epstein, M P Tu, C M Yin, R S Garofalo. Science 2001
9


Ageing as a risk factor for disease.
Teresa Niccoli, Linda Partridge. Curr Biol 2012
581
9

The threshold for polyglutamine-expansion protein aggregation and cellular toxicity is dynamic and influenced by aging in Caenorhabditis elegans.
James F Morley, Heather R Brignull, Jill J Weyers, Richard I Morimoto. Proc Natl Acad Sci U S A 2002
507
8


Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders.
Darren J Baker, Tobias Wijshake, Tamar Tchkonia, Nathan K LeBrasseur, Bennett G Childs, Bart van de Sluis, James L Kirkland, Jan M van Deursen. Nature 2011
8

Genetics: influence of TOR kinase on lifespan in C. elegans.
Tibor Vellai, Krisztina Takacs-Vellai, Yue Zhang, Attila L Kovacs, László Orosz, Fritz Müller. Nature 2003
715
8


Insulin/insulin-like growth factor signaling in C. elegans.
Coleen T Murphy, Patrick J Hu. WormBook 2013
207
8

Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases.
Claudio Franceschi, Judith Campisi. J Gerontol A Biol Sci Med Sci 2014
8

PQM-1 complements DAF-16 as a key transcriptional regulator of DAF-2-mediated development and longevity.
Ronald G Tepper, Jasmine Ashraf, Rachel Kaletsky, Gunnar Kleemann, Coleen T Murphy, Harmen J Bussemaker. Cell 2013
141
8

Functionally significant insulin-like growth factor I receptor mutations in centenarians.
Yousin Suh, Gil Atzmon, Mi-Ook Cho, David Hwang, Bingrong Liu, Daniel J Leahy, Nir Barzilai, Pinchas Cohen. Proc Natl Acad Sci U S A 2008
462
8

p38 MAPK regulates expression of immune response genes and contributes to longevity in C. elegans.
Emily R Troemel, Stephanie W Chu, Valerie Reinke, Siu Sylvia Lee, Frederick M Ausubel, Dennis H Kim. PLoS Genet 2006
403
8

Inhibition of mRNA translation extends lifespan in Caenorhabditis elegans.
Kally Z Pan, Julia E Palter, Aric N Rogers, Anders Olsen, Di Chen, Gordon J Lithgow, Pankaj Kapahi. Aging Cell 2007
323
7

Long-lived Drosophila with overexpressed dFOXO in adult fat body.
Maria E Giannakou, Martin Goss, Martin A Jünger, Ernst Hafen, Sally J Leevers, Linda Partridge. Science 2004
394
7

FOXO3A genotype is strongly associated with human longevity.
Bradley J Willcox, Timothy A Donlon, Qimei He, Randi Chen, John S Grove, Katsuhiko Yano, Kamal H Masaki, D Craig Willcox, Beatriz Rodriguez, J David Curb. Proc Natl Acad Sci U S A 2008
585
7

Stochastic and genetic factors influence tissue-specific decline in ageing C. elegans.
Laura A Herndon, Peter J Schmeissner, Justyna M Dudaronek, Paula A Brown, Kristin M Listner, Yuko Sakano, Marie C Paupard, David H Hall, Monica Driscoll. Nature 2002
705
7



Two pleiotropic classes of daf-2 mutation affect larval arrest, adult behavior, reproduction and longevity in Caenorhabditis elegans.
D Gems, A J Sutton, M L Sundermeyer, P S Albert, K V King, M L Edgley, P L Larsen, D L Riddle. Genetics 1998
481
7



Caloric restriction delays disease onset and mortality in rhesus monkeys.
Ricki J Colman, Rozalyn M Anderson, Sterling C Johnson, Erik K Kastman, Kristopher J Kosmatka, T Mark Beasley, David B Allison, Christina Cruzen, Heather A Simmons, Joseph W Kemnitz,[...]. Science 2009
6

The structure of the nervous system of the nematode Caenorhabditis elegans.
J G White, E Southgate, J N Thomson, S Brenner. Philos Trans R Soc Lond B Biol Sci 1986
6

TOR signaling and rapamycin influence longevity by regulating SKN-1/Nrf and DAF-16/FoxO.
Stacey Robida-Stubbs, Kira Glover-Cutter, Dudley W Lamming, Masaki Mizunuma, Sri Devi Narasimhan, Elke Neumann-Haefelin, David M Sabatini, T Keith Blackwell. Cell Metab 2012
338
6

The first long-lived mutants: discovery of the insulin/IGF-1 pathway for ageing.
Cynthia Kenyon. Philos Trans R Soc Lond B Biol Sci 2011
178
6

A conserved p38 MAP kinase pathway in Caenorhabditis elegans innate immunity.
Dennis H Kim, Rhonda Feinbaum, Geneviève Alloing, Fred E Emerson, Danielle A Garsin, Hideki Inoue, Miho Tanaka-Hino, Naoki Hisamoto, Kunihiro Matsumoto, Man-Wah Tan,[...]. Science 2002
530
6


With TOR, less is more: a key role for the conserved nutrient-sensing TOR pathway in aging.
Pankaj Kapahi, Di Chen, Aric N Rogers, Subhash D Katewa, Patrick Wai-Lun Li, Emma L Thomas, Lutz Kockel. Cell Metab 2010
433
6

eIF4E function in somatic cells modulates ageing in Caenorhabditis elegans.
Popi Syntichaki, Kostoula Troulinaki, Nektarios Tavernarakis. Nature 2007
230
6


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.