A citation-based method for searching scientific literature

M Serrano, G J Hannon, D Beach. Nature 1993
Times Cited: 3323







List of co-cited articles
1049 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


The serial cultivation of human diploid cell strains.
L HAYFLICK, P S MOORHEAD. Exp Cell Res 1961
16

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders.
Darren J Baker, Tobias Wijshake, Tamar Tchkonia, Nathan K LeBrasseur, Bennett G Childs, Bart van de Sluis, James L Kirkland, Jan M van Deursen. Nature 2011
16

A biomarker that identifies senescent human cells in culture and in aging skin in vivo.
G P Dimri, X Lee, G Basile, M Acosta, G Scott, C Roskelley, E E Medrano, M Linskens, I Rubelj, O Pereira-Smith. Proc Natl Acad Sci U S A 1995
16

Cellular Senescence: Defining a Path Forward.
Vassilis Gorgoulis, Peter D Adams, Andrea Alimonti, Dorothy C Bennett, Oliver Bischof, Cleo Bishop, Judith Campisi, Manuel Collado, Konstantinos Evangelou, Gerardo Ferbeyre,[...]. Cell 2019
674
15

Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan.
Darren J Baker, Bennett G Childs, Matej Durik, Melinde E Wijers, Cynthia J Sieben, Jian Zhong, Rachel A Saltness, Karthik B Jeganathan, Grace Casaclang Verzosa, Abdulmohammad Pezeshki,[...]. Nature 2016
15


Forging a signature of in vivo senescence.
Norman E Sharpless, Charles J Sherr. Nat Rev Cancer 2015
504
14

An essential role for senescent cells in optimal wound healing through secretion of PDGF-AA.
Marco Demaria, Naoko Ohtani, Sameh A Youssef, Francis Rodier, Wendy Toussaint, James R Mitchell, Remi-Martin Laberge, Jan Vijg, Harry Van Steeg, Martijn E T Dollé,[...]. Dev Cell 2014
873
14

Senescence is a developmental mechanism that contributes to embryonic growth and patterning.
Mekayla Storer, Alba Mas, Alexandre Robert-Moreno, Matteo Pecoraro, M Carmen Ortells, Valeria Di Giacomo, Reut Yosef, Noam Pilpel, Valery Krizhanovsky, James Sharpe,[...]. Cell 2013
609
14

The senescence-associated secretory phenotype: the dark side of tumor suppression.
Jean-Philippe Coppé, Pierre-Yves Desprez, Ana Krtolica, Judith Campisi. Annu Rev Pathol 2010
14

Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas.
Wen Xue, Lars Zender, Cornelius Miething, Ross A Dickins, Eva Hernando, Valery Krizhanovsky, Carlos Cordon-Cardo, Scott W Lowe. Nature 2007
13

Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor.
Jean-Philippe Coppé, Christopher K Patil, Francis Rodier, Yu Sun, Denise P Muñoz, Joshua Goldstein, Peter S Nelson, Pierre-Yves Desprez, Judith Campisi. PLoS Biol 2008
13

Programmed cell senescence during mammalian embryonic development.
Daniel Muñoz-Espín, Marta Cañamero, Antonio Maraver, Gonzalo Gómez-López, Julio Contreras, Silvia Murillo-Cuesta, Alfonso Rodríguez-Baeza, Isabel Varela-Nieto, Jesús Ruberte, Manuel Collado,[...]. Cell 2013
739
12

Senescence surveillance of pre-malignant hepatocytes limits liver cancer development.
Tae-Won Kang, Tetyana Yevsa, Norman Woller, Lisa Hoenicke, Torsten Wuestefeld, Daniel Dauch, Anja Hohmeyer, Marcus Gereke, Ramona Rudalska, Anna Potapova,[...]. Nature 2011
860
12

Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence.
Masashi Narita, Sabrina Nũnez, Edith Heard, Masako Narita, Athena W Lin, Stephen A Hearn, David L Spector, Gregory J Hannon, Scott W Lowe. Cell 2003
12

Unmasking Transcriptional Heterogeneity in Senescent Cells.
Alejandra Hernandez-Segura, Tristan V de Jong, Simon Melov, Victor Guryev, Judith Campisi, Marco Demaria. Curr Biol 2017
295
11

Senescent intimal foam cells are deleterious at all stages of atherosclerosis.
Bennett G Childs, Darren J Baker, Tobias Wijshake, Cheryl A Conover, Judith Campisi, Jan M van Deursen. Science 2016
523
11

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion.
Francis Rodier, Jean-Philippe Coppé, Christopher K Patil, Wieteke A M Hoeijmakers, Denise P Muñoz, Saba R Raza, Adam Freund, Eric Campeau, Albert R Davalos, Judith Campisi. Nat Cell Biol 2009
11

The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.
Yi Zhu, Tamara Tchkonia, Tamar Pirtskhalava, Adam C Gower, Husheng Ding, Nino Giorgadze, Allyson K Palmer, Yuji Ikeno, Gene B Hubbard, Marc Lenburg,[...]. Aging Cell 2015
929
11

Cellular Senescence Promotes Adverse Effects of Chemotherapy and Cancer Relapse.
Marco Demaria, Monique N O'Leary, Jianhui Chang, Lijian Shao, Su Liu, Fatouma Alimirah, Kristin Koenig, Catherine Le, Natalia Mitin, Allison M Deal,[...]. Cancer Discov 2017
523
10

Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging.
Marjolein P Baar, Renata M C Brandt, Diana A Putavet, Julian D D Klein, Kasper W J Derks, Benjamin R M Bourgeois, Sarah Stryeck, Yvonne Rijksen, Hester van Willigenburg, Danny A Feijtel,[...]. Cell 2017
635
10

Local clearance of senescent cells attenuates the development of post-traumatic osteoarthritis and creates a pro-regenerative environment.
Ok Hee Jeon, Chaekyu Kim, Remi-Martin Laberge, Marco Demaria, Sona Rathod, Alain P Vasserot, Jae Wook Chung, Do Hun Kim, Yan Poon, Nathaniel David,[...]. Nat Med 2017
622
10

Hallmarks of Cellular Senescence.
Alejandra Hernandez-Segura, Jamil Nehme, Marco Demaria. Trends Cell Biol 2018
706
10

Targeting senescent cells in translational medicine.
Marta Paez-Ribes, Estela González-Gualda, Gary J Doherty, Daniel Muñoz-Espín. EMBO Mol Med 2019
99
9

Senescence of activated stellate cells limits liver fibrosis.
Valery Krizhanovsky, Monica Yon, Ross A Dickins, Stephen Hearn, Janelle Simon, Cornelius Miething, Herman Yee, Lars Zender, Scott W Lowe. Cell 2008
9

Targeting cellular senescence prevents age-related bone loss in mice.
Joshua N Farr, Ming Xu, Megan M Weivoda, David G Monroe, Daniel G Fraser, Jennifer L Onken, Brittany A Negley, Jad G Sfeir, Mikolaj B Ogrodnik, Christine M Hachfeld,[...]. Nat Med 2017
441
9

A complex secretory program orchestrated by the inflammasome controls paracrine senescence.
Juan Carlos Acosta, Ana Banito, Torsten Wuestefeld, Athena Georgilis, Peggy Janich, Jennifer P Morton, Dimitris Athineos, Tae-Won Kang, Felix Lasitschka, Mindaugas Andrulis,[...]. Nat Cell Biol 2013
9

Tumor suppressor and aging biomarker p16(INK4a) induces cellular senescence without the associated inflammatory secretory phenotype.
Jean-Philippe Coppé, Francis Rodier, Christopher K Patil, Adam Freund, Pierre-Yves Desprez, Judith Campisi. J Biol Chem 2011
270
9

Senescence-associated reprogramming promotes cancer stemness.
Maja Milanovic, Dorothy N Y Fan, Dimitri Belenki, J Henry M Däbritz, Zhen Zhao, Yong Yu, Jan R Dörr, Lora Dimitrova, Dido Lenze, Ines A Monteiro Barbosa,[...]. Nature 2018
413
9


Ink4a/Arf expression is a biomarker of aging.
Janakiraman Krishnamurthy, Chad Torrice, Matthew R Ramsey, Grigoriy I Kovalev, Khalid Al-Regaiey, Lishan Su, Norman E Sharpless. J Clin Invest 2004
994
9

MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation.
Remi-Martin Laberge, Yu Sun, Arturo V Orjalo, Christopher K Patil, Adam Freund, Lili Zhou, Samuel C Curran, Albert R Davalos, Kathleen A Wilson-Edell, Su Liu,[...]. Nat Cell Biol 2015
564
9

Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice.
Jianhui Chang, Yingying Wang, Lijian Shao, Remi-Martin Laberge, Marco Demaria, Judith Campisi, Krishnamurthy Janakiraman, Norman E Sharpless, Sheng Ding, Wei Feng,[...]. Nat Med 2016
823
9

Senescence in Health and Disease.
Shenghui He, Norman E Sharpless. Cell 2017
613
9


Hallmarks of cancer: the next generation.
Douglas Hanahan, Robert A Weinberg. Cell 2011
9

PD 0332991, a selective cyclin D kinase 4/6 inhibitor, preferentially inhibits proliferation of luminal estrogen receptor-positive human breast cancer cell lines in vitro.
Richard S Finn, Judy Dering, Dylan Conklin, Ondrej Kalous, David J Cohen, Amrita J Desai, Charles Ginther, Mohammad Atefi, Isan Chen, Camilla Fowst,[...]. Breast Cancer Res 2009
890
8

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases.
J W Harper, G R Adami, N Wei, K Keyomarsi, S J Elledge. Cell 1993
8

Senescence-associated beta-galactosidase is lysosomal beta-galactosidase.
Bo Yun Lee, Jung A Han, Jun Sub Im, Amelia Morrone, Kimberly Johung, Edward C Goodwin, Wim J Kleijer, Daniel DiMaio, Eun Seong Hwang. Aging Cell 2006
638
8

Cellular senescence: from physiology to pathology.
Daniel Muñoz-Espín, Manuel Serrano. Nat Rev Mol Cell Biol 2014
8

The essence of senescence.
Thomas Kuilman, Chrysiis Michaloglou, Wolter J Mooi, Daniel S Peeper. Genes Dev 2010
8

Reversal of human cellular senescence: roles of the p53 and p16 pathways.
Christian M Beauséjour, Ana Krtolica, Francesco Galimi, Masashi Narita, Scott W Lowe, Paul Yaswen, Judith Campisi. EMBO J 2003
894
8

NOTCH1 mediates a switch between two distinct secretomes during senescence.
Matthew Hoare, Yoko Ito, Tae-Won Kang, Michael P Weekes, Nicholas J Matheson, Daniel A Patten, Shishir Shetty, Aled J Parry, Suraj Menon, Rafik Salama,[...]. Nat Cell Biol 2016
226
8

Senolytics improve physical function and increase lifespan in old age.
Ming Xu, Tamar Pirtskhalava, Joshua N Farr, Bettina M Weigand, Allyson K Palmer, Megan M Weivoda, Christina L Inman, Mikolaj B Ogrodnik, Christine M Hachfeld, Daniel G Fraser,[...]. Nat Med 2018
750
8

Feedback between p21 and reactive oxygen production is necessary for cell senescence.
João F Passos, Glyn Nelson, Chunfang Wang, Torsten Richter, Cedric Simillion, Carole J Proctor, Satomi Miwa, Sharon Olijslagers, Jennifer Hallinan, Anil Wipat,[...]. Mol Syst Biol 2010
535
8

Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging.
A Krtolica, S Parrinello, S Lockett, P Y Desprez, J Campisi. Proc Natl Acad Sci U S A 2001
8


A cell cycle regulator potentially involved in genesis of many tumor types.
A Kamb, N A Gruis, J Weaver-Feldhaus, Q Liu, K Harshman, S V Tavtigian, E Stockert, R S Day, B E Johnson, M H Skolnick. Science 1994
8

Cellular senescence mediates fibrotic pulmonary disease.
Marissa J Schafer, Thomas A White, Koji Iijima, Andrew J Haak, Giovanni Ligresti, Elizabeth J Atkinson, Ann L Oberg, Jodie Birch, Hanna Salmonowicz, Yi Zhu,[...]. Nat Commun 2017
621
7

CDK4/6 inhibition triggers anti-tumour immunity.
Shom Goel, Molly J DeCristo, April C Watt, Haley BrinJones, Jaclyn Sceneay, Ben B Li, Naveed Khan, Jessalyn M Ubellacker, Shaozhen Xie, Otto Metzger-Filho,[...]. Nature 2017
640
7


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.