C A Hodgkinson, K J Moore, A Nakayama, E Steingrímsson, N G Copeland, N A Jenkins, H Arnheiter. Cell 1993
Times Cited: 899
Times Cited: 899
Times Cited
Times Co-cited
Similarity
Melanocytes and the microphthalmia transcription factor network.
Eiríkur Steingrímsson, Neal G Copeland, Nancy A Jenkins. Annu Rev Genet 2004
Eiríkur Steingrímsson, Neal G Copeland, Nancy A Jenkins. Annu Rev Genet 2004
28
microphthalmia, a critical factor in melanocyte development, defines a discrete transcription factor family.
T J Hemesath, E Steingrímsson, G McGill, M J Hansen, J Vaught, C A Hodgkinson, H Arnheiter, N G Copeland, N A Jenkins, D E Fisher. Genes Dev 1994
T J Hemesath, E Steingrímsson, G McGill, M J Hansen, J Vaught, C A Hodgkinson, H Arnheiter, N G Copeland, N A Jenkins, D E Fisher. Genes Dev 1994
25
Molecular basis of mouse microphthalmia (mi) mutations helps explain their developmental and phenotypic consequences.
E Steingrímsson, K J Moore, M L Lamoreux, A R Ferré-D'Amaré, S K Burley, D C Zimring, L C Skow, C A Hodgkinson, H Arnheiter, N G Copeland. Nat Genet 1994
E Steingrímsson, K J Moore, M L Lamoreux, A R Ferré-D'Amaré, S K Burley, D C Zimring, L C Skow, C A Hodgkinson, H Arnheiter, N G Copeland. Nat Genet 1994
22
Biallelic Mutations in MITF Cause Coloboma, Osteopetrosis, Microphthalmia, Macrocephaly, Albinism, and Deafness.
Aman George, Dina J Zand, Robert B Hufnagel, Ruchi Sharma, Yuri V Sergeev, Janet M Legare, Gregory M Rice, Jessica A Scott Schwoerer, Mariana Rius, Laura Tetri,[...]. Am J Hum Genet 2016
Aman George, Dina J Zand, Robert B Hufnagel, Ruchi Sharma, Yuri V Sergeev, Janet M Legare, Gregory M Rice, Jessica A Scott Schwoerer, Mariana Rius, Laura Tetri,[...]. Am J Hum Genet 2016
42
Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma.
Levi A Garraway, Hans R Widlund, Mark A Rubin, Gad Getz, Aaron J Berger, Sridhar Ramaswamy, Rameen Beroukhim, Danny A Milner, Scott R Granter, Jinyan Du,[...]. Nature 2005
Levi A Garraway, Hans R Widlund, Mark A Rubin, Gad Getz, Aaron J Berger, Sridhar Ramaswamy, Rameen Beroukhim, Danny A Milner, Scott R Granter, Jinyan Du,[...]. Nature 2005
18
A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma.
Corine Bertolotto, Fabienne Lesueur, Sandy Giuliano, Thomas Strub, Mahaut de Lichy, Karine Bille, Philippe Dessen, Benoit d'Hayer, Hamida Mohamdi, Audrey Remenieras,[...]. Nature 2011
Corine Bertolotto, Fabienne Lesueur, Sandy Giuliano, Thomas Strub, Mahaut de Lichy, Karine Bille, Philippe Dessen, Benoit d'Hayer, Hamida Mohamdi, Audrey Remenieras,[...]. Nature 2011
18
c-Kit triggers dual phosphorylations, which couple activation and degradation of the essential melanocyte factor Mi.
M Wu, T J Hemesath, C M Takemoto, M A Horstmann, A G Wells, E R Price, D Z Fisher, D E Fisher. Genes Dev 2000
M Wu, T J Hemesath, C M Takemoto, M A Horstmann, A G Wells, E R Price, D Z Fisher, D E Fisher. Genes Dev 2000
15
Restricted leucine zipper dimerization and specificity of DNA recognition of the melanocyte master regulator MITF.
Vivian Pogenberg, Margrét H Ogmundsdóttir, Kristín Bergsteinsdóttir, Alexander Schepsky, Bengt Phung, Viktor Deineko, Morlin Milewski, Eiríkur Steingrímsson, Matthias Wilmanns. Genes Dev 2012
Vivian Pogenberg, Margrét H Ogmundsdóttir, Kristín Bergsteinsdóttir, Alexander Schepsky, Bengt Phung, Viktor Deineko, Morlin Milewski, Eiríkur Steingrímsson, Matthias Wilmanns. Genes Dev 2012
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Waardenburg syndrome type 2 caused by mutations in the human microphthalmia (MITF) gene.
M Tassabehji, V E Newton, A P Read. Nat Genet 1994
M Tassabehji, V E Newton, A P Read. Nat Genet 1994
14
Essential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma.
T Strub, S Giuliano, T Ye, C Bonet, C Keime, D Kobi, S Le Gras, M Cormont, R Ballotti, C Bertolotto,[...]. Oncogene 2011
T Strub, S Giuliano, T Ye, C Bonet, C Keime, D Kobi, S Le Gras, M Cormont, R Ballotti, C Bertolotto,[...]. Oncogene 2011
14
Fifteen-year quest for microphthalmia-associated transcription factor target genes.
Yann Cheli, Mickael Ohanna, Robert Ballotti, Corine Bertolotto. Pigment Cell Melanoma Res 2010
Yann Cheli, Mickael Ohanna, Robert Ballotti, Corine Bertolotto. Pigment Cell Melanoma Res 2010
14
MITF: master regulator of melanocyte development and melanoma oncogene.
Carmit Levy, Mehdi Khaled, David E Fisher. Trends Mol Med 2006
Carmit Levy, Mehdi Khaled, David E Fisher. Trends Mol Med 2006
14
Alternative promoter use in eye development: the complex role and regulation of the transcription factor MITF.
Kapil Bharti, Wenfang Liu, Tamas Csermely, Stefano Bertuzzi, Heinz Arnheiter. Development 2008
Kapil Bharti, Wenfang Liu, Tamas Csermely, Stefano Bertuzzi, Heinz Arnheiter. Development 2008
14
Oncogenic BRAF regulates oxidative metabolism via PGC1α and MITF.
Rizwan Haq, Jonathan Shoag, Pedro Andreu-Perez, Satoru Yokoyama, Hannah Edelman, Glenn C Rowe, Dennie T Frederick, Aeron D Hurley, Abhinav Nellore, Andrew L Kung,[...]. Cancer Cell 2013
Rizwan Haq, Jonathan Shoag, Pedro Andreu-Perez, Satoru Yokoyama, Hannah Edelman, Glenn C Rowe, Dennie T Frederick, Aeron D Hurley, Abhinav Nellore, Andrew L Kung,[...]. Cancer Cell 2013
13
Bcl2 regulation by the melanocyte master regulator Mitf modulates lineage survival and melanoma cell viability.
Gaël G McGill, Martin Horstmann, Hans R Widlund, Jinyan Du, Gabriela Motyckova, Emi K Nishimura, Yi-Ling Lin, Sridhar Ramaswamy, William Avery, Han-Fei Ding,[...]. Cell 2002
Gaël G McGill, Martin Horstmann, Hans R Widlund, Jinyan Du, Gabriela Motyckova, Emi K Nishimura, Yi-Ling Lin, Sridhar Ramaswamy, William Avery, Han-Fei Ding,[...]. Cell 2002
13
MAP kinase links the transcription factor Microphthalmia to c-Kit signalling in melanocytes.
T J Hemesath, E R Price, C Takemoto, T Badalian, D E Fisher. Nature 1998
T J Hemesath, E R Price, C Takemoto, T Badalian, D E Fisher. Nature 1998
12
Mitf cooperates with Rb1 and activates p21Cip1 expression to regulate cell cycle progression.
Suzanne Carreira, Jane Goodall, Isil Aksan, S Anna La Rocca, Marie-Dominique Galibert, Laurence Denat, Lionel Larue, Colin R Goding. Nature 2005
Suzanne Carreira, Jane Goodall, Isil Aksan, S Anna La Rocca, Marie-Dominique Galibert, Laurence Denat, Lionel Larue, Colin R Goding. Nature 2005
12
A regulatory loop involving PAX6, MITF, and WNT signaling controls retinal pigment epithelium development.
Kapil Bharti, Melanie Gasper, Jingxing Ou, Martha Brucato, Katharina Clore-Gronenborn, James Pickel, Heinz Arnheiter. PLoS Genet 2012
Kapil Bharti, Melanie Gasper, Jingxing Ou, Martha Brucato, Katharina Clore-Gronenborn, James Pickel, Heinz Arnheiter. PLoS Genet 2012
13
A helix-loop-helix transcription factor-like gene is located at the mi locus.
M J Hughes, J B Lingrel, J M Krakowsky, K P Anderson. J Biol Chem 1993
M J Hughes, J B Lingrel, J M Krakowsky, K P Anderson. J Biol Chem 1993
11
Transcription factor MITF and remodeller BRG1 define chromatin organisation at regulatory elements in melanoma cells.
Patrick Laurette, Thomas Strub, Dana Koludrovic, Céline Keime, Stéphanie Le Gras, Hannah Seberg, Eric Van Otterloo, Hana Imrichova, Robert Siddaway, Stein Aerts,[...]. Elife 2015
Patrick Laurette, Thomas Strub, Dana Koludrovic, Céline Keime, Stéphanie Le Gras, Hannah Seberg, Eric Van Otterloo, Hana Imrichova, Robert Siddaway, Stein Aerts,[...]. Elife 2015
11
Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism.
Rushika M Perera, Svetlana Stoykova, Brandon N Nicolay, Kenneth N Ross, Julien Fitamant, Myriam Boukhali, Justine Lengrand, Vikram Deshpande, Martin K Selig, Cristina R Ferrone,[...]. Nature 2015
Rushika M Perera, Svetlana Stoykova, Brandon N Nicolay, Kenneth N Ross, Julien Fitamant, Myriam Boukhali, Justine Lengrand, Vikram Deshpande, Martin K Selig, Cristina R Ferrone,[...]. Nature 2015
11
MITF drives endolysosomal biogenesis and potentiates Wnt signaling in melanoma cells.
Diego Ploper, Vincent F Taelman, Lidia Robert, Brian S Perez, Björn Titz, Hsiao-Wang Chen, Thomas G Graeber, Erika von Euw, Antoni Ribas, Edward M De Robertis. Proc Natl Acad Sci U S A 2015
Diego Ploper, Vincent F Taelman, Lidia Robert, Brian S Perez, Björn Titz, Hsiao-Wang Chen, Thomas G Graeber, Erika von Euw, Antoni Ribas, Edward M De Robertis. Proc Natl Acad Sci U S A 2015
11
A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma.
Satoru Yokoyama, Susan L Woods, Glen M Boyle, Lauren G Aoude, Stuart MacGregor, Victoria Zismann, Michael Gartside, Anne E Cust, Rizwan Haq, Mark Harland,[...]. Nature 2011
Satoru Yokoyama, Susan L Woods, Glen M Boyle, Lauren G Aoude, Stuart MacGregor, Victoria Zismann, Michael Gartside, Anne E Cust, Rizwan Haq, Mark Harland,[...]. Nature 2011
11
Mitf regulation of Dia1 controls melanoma proliferation and invasiveness.
Suzanne Carreira, Jane Goodall, Laurence Denat, Mercedes Rodriguez, Paolo Nuciforo, Keith S Hoek, Alessandro Testori, Lionel Larue, Colin R Goding. Genes Dev 2006
Suzanne Carreira, Jane Goodall, Laurence Denat, Mercedes Rodriguez, Paolo Nuciforo, Keith S Hoek, Alessandro Testori, Lionel Larue, Colin R Goding. Genes Dev 2006
11
nacre encodes a zebrafish microphthalmia-related protein that regulates neural-crest-derived pigment cell fate.
J A Lister, C P Robertson, T Lepage, S L Johnson, D W Raible. Development 1999
J A Lister, C P Robertson, T Lepage, S L Johnson, D W Raible. Development 1999
11
A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB.
Carmine Settembre, Roberto Zoncu, Diego L Medina, Francesco Vetrini, Serkan Erdin, SerpilUckac Erdin, Tuong Huynh, Mathieu Ferron, Gerard Karsenty, Michel C Vellard,[...]. EMBO J 2012
Carmine Settembre, Roberto Zoncu, Diego L Medina, Francesco Vetrini, Serkan Erdin, SerpilUckac Erdin, Tuong Huynh, Mathieu Ferron, Gerard Karsenty, Michel C Vellard,[...]. EMBO J 2012
10
The transcription factor TFEB links mTORC1 signaling to transcriptional control of lysosome homeostasis.
Agnes Roczniak-Ferguson, Constance S Petit, Florian Froehlich, Sharon Qian, Jennifer Ky, Brittany Angarola, Tobias C Walther, Shawn M Ferguson. Sci Signal 2012
Agnes Roczniak-Ferguson, Constance S Petit, Florian Froehlich, Sharon Qian, Jennifer Ky, Brittany Angarola, Tobias C Walther, Shawn M Ferguson. Sci Signal 2012
10
Mitf and Tfe3, two members of the Mitf-Tfe family of bHLH-Zip transcription factors, have important but functionally redundant roles in osteoclast development.
Eiríkur Steingrimsson, Lino Tessarollo, Bhavani Pathak, Ling Hou, Heinz Arnheiter, Neal G Copeland, Nancy A Jenkins. Proc Natl Acad Sci U S A 2002
Eiríkur Steingrimsson, Lino Tessarollo, Bhavani Pathak, Ling Hou, Heinz Arnheiter, Neal G Copeland, Nancy A Jenkins. Proc Natl Acad Sci U S A 2002
10
TFEB links autophagy to lysosomal biogenesis.
Carmine Settembre, Chiara Di Malta, Vinicia Assunta Polito, Moises Garcia Arencibia, Francesco Vetrini, Serkan Erdin, Serpil Uckac Erdin, Tuong Huynh, Diego Medina, Pasqualina Colella,[...]. Science 2011
Carmine Settembre, Chiara Di Malta, Vinicia Assunta Polito, Moises Garcia Arencibia, Francesco Vetrini, Serkan Erdin, Serpil Uckac Erdin, Tuong Huynh, Diego Medina, Pasqualina Colella,[...]. Science 2011
10
Cancer stem cells versus phenotype-switching in melanoma.
Keith S Hoek, Colin R Goding. Pigment Cell Melanoma Res 2010
Keith S Hoek, Colin R Goding. Pigment Cell Melanoma Res 2010
10
Signaling and transcriptional regulation in early mammalian eye development: a link between FGF and MITF.
M Nguyen, H Arnheiter. Development 2000
M Nguyen, H Arnheiter. Development 2000
10
The other pigment cell: specification and development of the pigmented epithelium of the vertebrate eye.
Kapil Bharti, Minh-Thanh T Nguyen, Susan Skuntz, Stefano Bertuzzi, Heinz Arnheiter. Pigment Cell Res 2006
Kapil Bharti, Minh-Thanh T Nguyen, Susan Skuntz, Stefano Bertuzzi, Heinz Arnheiter. Pigment Cell Res 2006
10
Microphthalmia transcription factor is a target of the p38 MAPK pathway in response to receptor activator of NF-kappa B ligand signaling.
Kim C Mansky, Uma Sankar, Jiahuai Han, Michael C Ostrowski. J Biol Chem 2002
Kim C Mansky, Uma Sankar, Jiahuai Han, Michael C Ostrowski. J Biol Chem 2002
10
MITF mutations associated with pigment deficiency syndromes and melanoma have different effects on protein function.
Christine Grill, Kristín Bergsteinsdóttir, Margrét H Ogmundsdóttir, Vivian Pogenberg, Alexander Schepsky, Matthias Wilmanns, Veronique Pingault, Eiríkur Steingrímsson. Hum Mol Genet 2013
Christine Grill, Kristín Bergsteinsdóttir, Margrét H Ogmundsdóttir, Vivian Pogenberg, Alexander Schepsky, Matthias Wilmanns, Veronique Pingault, Eiríkur Steingrímsson. Hum Mol Genet 2013
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Review and update of mutations causing Waardenburg syndrome.
Véronique Pingault, Dorothée Ente, Florence Dastot-Le Moal, Michel Goossens, Sandrine Marlin, Nadège Bondurand. Hum Mutat 2010
Véronique Pingault, Dorothée Ente, Florence Dastot-Le Moal, Michel Goossens, Sandrine Marlin, Nadège Bondurand. Hum Mutat 2010
10
PGC1α expression defines a subset of human melanoma tumors with increased mitochondrial capacity and resistance to oxidative stress.
Francisca Vazquez, Ji-Hong Lim, Helen Chim, Kavita Bhalla, Geoff Girnun, Kerry Pierce, Clary B Clish, Scott R Granter, Hans R Widlund, Bruce M Spiegelman,[...]. Cancer Cell 2013
Francisca Vazquez, Ji-Hong Lim, Helen Chim, Kavita Bhalla, Geoff Girnun, Kerry Pierce, Clary B Clish, Scott R Granter, Hans R Widlund, Bruce M Spiegelman,[...]. Cancer Cell 2013
9
A gene for Waardenburg syndrome type 2 maps close to the human homologue of the microphthalmia gene at chromosome 3p12-p14.1.
A E Hughes, V E Newton, X Z Liu, A P Read. Nat Genet 1994
A E Hughes, V E Newton, X Z Liu, A P Read. Nat Genet 1994
9
Genomic analysis of the Microphthalmia locus and identification of the MITF-J/Mitf-J isoform.
Christine L Hershey, David E Fisher. Gene 2005
Christine L Hershey, David E Fisher. Gene 2005
12
Critical role of CDK2 for melanoma growth linked to its melanocyte-specific transcriptional regulation by MITF.
Jinyan Du, Hans R Widlund, Martin A Horstmann, Sridhar Ramaswamy, Ken Ross, Wade E Huber, Emi K Nishimura, Todd R Golub, David E Fisher. Cancer Cell 2004
Jinyan Du, Hans R Widlund, Martin A Horstmann, Sridhar Ramaswamy, Ken Ross, Wade E Huber, Emi K Nishimura, Todd R Golub, David E Fisher. Cancer Cell 2004
9
Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma.
Judith Müller, Oscar Krijgsman, Jennifer Tsoi, Lidia Robert, Willy Hugo, Chunying Song, Xiangju Kong, Patricia A Possik, Paulien D M Cornelissen-Steijger, Marnix H Geukes Foppen,[...]. Nat Commun 2014
Judith Müller, Oscar Krijgsman, Jennifer Tsoi, Lidia Robert, Willy Hugo, Chunying Song, Xiangju Kong, Patricia A Possik, Paulien D M Cornelissen-Steijger, Marnix H Geukes Foppen,[...]. Nat Commun 2014
9
A melanoma cell state distinction influences sensitivity to MAPK pathway inhibitors.
David J Konieczkowski, Cory M Johannessen, Omar Abudayyeh, Jong Wook Kim, Zachary A Cooper, Adriano Piris, Dennie T Frederick, Michal Barzily-Rokni, Ravid Straussman, Rizwan Haq,[...]. Cancer Discov 2014
David J Konieczkowski, Cory M Johannessen, Omar Abudayyeh, Jong Wook Kim, Zachary A Cooper, Adriano Piris, Dennie T Frederick, Michal Barzily-Rokni, Ravid Straussman, Rizwan Haq,[...]. Cancer Discov 2014
9
Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature.
Keith S Hoek, Natalie C Schlegel, Patricia Brafford, Antje Sucker, Selma Ugurel, Rajiv Kumar, Barbara L Weber, Katherine L Nathanson, David J Phillips, Meenhard Herlyn,[...]. Pigment Cell Res 2006
Keith S Hoek, Natalie C Schlegel, Patricia Brafford, Antje Sucker, Selma Ugurel, Rajiv Kumar, Barbara L Weber, Katherine L Nathanson, David J Phillips, Meenhard Herlyn,[...]. Pigment Cell Res 2006
9
Regulation of microphthalmia-associated transcription factor MITF protein levels by association with the ubiquitin-conjugating enzyme hUBC9.
W Xu, L Gong, M M Haddad, O Bischof, J Campisi, E T Yeh, E E Medrano. Exp Cell Res 2000
W Xu, L Gong, M M Haddad, O Bischof, J Campisi, E T Yeh, E E Medrano. Exp Cell Res 2000
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A gene network regulating lysosomal biogenesis and function.
Marco Sardiello, Michela Palmieri, Alberto di Ronza, Diego Luis Medina, Marta Valenza, Vincenzo Alessandro Gennarino, Chiara Di Malta, Francesca Donaudy, Valerio Embrione, Roman S Polishchuk,[...]. Science 2009
Marco Sardiello, Michela Palmieri, Alberto di Ronza, Diego Luis Medina, Marta Valenza, Vincenzo Alessandro Gennarino, Chiara Di Malta, Francesca Donaudy, Valerio Embrione, Roman S Polishchuk,[...]. Science 2009
9
TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop.
Carmine Settembre, Rossella De Cegli, Gelsomina Mansueto, Pradip K Saha, Francesco Vetrini, Orane Visvikis, Tuong Huynh, Annamaria Carissimo, Donna Palmer, Tiemo Jürgen Klisch,[...]. Nat Cell Biol 2013
Carmine Settembre, Rossella De Cegli, Gelsomina Mansueto, Pradip K Saha, Francesco Vetrini, Orane Visvikis, Tuong Huynh, Annamaria Carissimo, Donna Palmer, Tiemo Jürgen Klisch,[...]. Nat Cell Biol 2013
9
Mutations in microphthalmia, the mouse homolog of the human deafness gene MITF, affect neuroepithelial and neural crest-derived melanocytes differently.
A Nakayama, M T Nguyen, C C Chen, K Opdecamp, C A Hodgkinson, H Arnheiter. Mech Dev 1998
A Nakayama, M T Nguyen, C C Chen, K Opdecamp, C A Hodgkinson, H Arnheiter. Mech Dev 1998
9
Direct regulation of nacre, a zebrafish MITF homolog required for pigment cell formation, by the Wnt pathway.
R I Dorsky, D W Raible, R T Moon. Genes Dev 2000
R I Dorsky, D W Raible, R T Moon. Genes Dev 2000
8
Induction of melanocyte-specific microphthalmia-associated transcription factor by Wnt-3a.
K Takeda, K Yasumoto, R Takada, S Takada, K Watanabe, T Udono, H Saito, K Takahashi, S Shibahara. J Biol Chem 2000
K Takeda, K Yasumoto, R Takada, S Takada, K Watanabe, T Udono, H Saito, K Takahashi, S Shibahara. J Biol Chem 2000
8
Mitf is a master regulator of the v-ATPase, forming a control module for cellular homeostasis with v-ATPase and TORC1.
Tianyi Zhang, Qingxiang Zhou, Margret Helga Ogmundsdottir, Katrin Möller, Robert Siddaway, Lionel Larue, Michael Hsing, Sek Won Kong, Colin Ronald Goding, Arnar Palsson,[...]. J Cell Sci 2015
Tianyi Zhang, Qingxiang Zhou, Margret Helga Ogmundsdottir, Katrin Möller, Robert Siddaway, Lionel Larue, Michael Hsing, Sek Won Kong, Colin Ronald Goding, Arnar Palsson,[...]. J Cell Sci 2015
15
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.