A citation-based method for searching scientific literature

E H Corder, A M Saunders, W J Strittmatter, D E Schmechel, P C Gaskell, G W Small, A D Roses, J L Haines, M A Pericak-Vance. Science 1993
Times Cited: 6541







List of co-cited articles
942 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.
Brian W Kunkle, Benjamin Grenier-Boley, Rebecca Sims, Joshua C Bis, Vincent Damotte, Adam C Naj, Anne Boland, Maria Vronskaya, Sven J van der Lee, Alexandre Amlie-Wolf,[...]. Nat Genet 2019
788
20

Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium.
L A Farrer, L A Cupples, J L Haines, B Hyman, W A Kukull, R Mayeux, R H Myers, M A Pericak-Vance, N Risch, C M van Duijn. JAMA 1997
19

Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease.
E H Corder, A M Saunders, N J Risch, W J Strittmatter, D E Schmechel, P C Gaskell, J B Rimmler, P A Locke, P M Conneally, K E Schmader. Nat Genet 1994
17

Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy.
Chia-Chen Liu, Chia-Chan Liu, Takahisa Kanekiyo, Huaxi Xu, Guojun Bu. Nat Rev Neurol 2013
16

Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease.
A M Saunders, W J Strittmatter, D Schmechel, P H George-Hyslop, M A Pericak-Vance, S H Joo, B L Rosi, J F Gusella, D R Crapper-MacLachlan, M J Alberts. Neurology 1993
15

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease.
W J Strittmatter, A M Saunders, D Schmechel, M Pericak-Vance, J Enghild, G S Salvesen, A D Roses. Proc Natl Acad Sci U S A 1993
13

The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases.
Susanne Krasemann, Charlotte Madore, Ron Cialic, Caroline Baufeld, Narghes Calcagno, Rachid El Fatimy, Lien Beckers, Elaine O'Loughlin, Yang Xu, Zain Fanek,[...]. Immunity 2017
901
12

ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy.
Yang Shi, Kaoru Yamada, Shane Antony Liddelow, Scott T Smith, Lingzhi Zhao, Wenjie Luo, Richard M Tsai, Salvatore Spina, Lea T Grinberg, Julio C Rojas,[...]. Nature 2017
477
12

Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
Iris E Jansen, Jeanne E Savage, Kyoko Watanabe, Julien Bryois, Dylan M Williams, Stacy Steinberg, Julia Sealock, Ida K Karlsson, Sara Hägg, Lavinia Athanasiu,[...]. Nat Genet 2019
657
12

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
J C Lambert, C A Ibrahim-Verbaas, D Harold, A C Naj, R Sims, C Bellenguez, A L DeStafano, J C Bis, G W Beecham, B Grenier-Boley,[...]. Nat Genet 2013
12

A Quarter Century of APOE and Alzheimer's Disease: Progress to Date and the Path Forward.
Michaël E Belloy, Valerio Napolioni, Michael D Greicius. Neuron 2019
154
12

Apolipoprotein E and Alzheimer disease: pathobiology and targeting strategies.
Yu Yamazaki, Na Zhao, Thomas R Caulfield, Chia-Chen Liu, Guojun Bu. Nat Rev Neurol 2019
285
12

Variant of TREM2 associated with the risk of Alzheimer's disease.
Thorlakur Jonsson, Hreinn Stefansson, Stacy Steinberg, Ingileif Jonsdottir, Palmi V Jonsson, Jon Snaedal, Sigurbjorn Bjornsson, Johanna Huttenlocher, Allan I Levey, James J Lah,[...]. N Engl J Med 2013
12

NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease.
Clifford R Jack, David A Bennett, Kaj Blennow, Maria C Carrillo, Billy Dunn, Samantha Budd Haeberlein, David M Holtzman, William Jagust, Frank Jessen, Jason Karlawish,[...]. Alzheimers Dement 2018
11

A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease.
Hadas Keren-Shaul, Amit Spinrad, Assaf Weiner, Orit Matcovitch-Natan, Raz Dvir-Szternfeld, Tyler K Ulland, Eyal David, Kuti Baruch, David Lara-Astaiso, Beata Toth,[...]. Cell 2017
11

The role of apolipoprotein E in Alzheimer's disease.
Jungsu Kim, Jacob M Basak, David M Holtzman. Neuron 2009
929
11

APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer's Disease Phenotypes in Human iPSC-Derived Brain Cell Types.
Yuan-Ta Lin, Jinsoo Seo, Fan Gao, Heather M Feldman, Hsin-Lan Wen, Jay Penney, Hugh P Cam, Elizabeta Gjoneska, Waseem K Raja, Jemmie Cheng,[...]. Neuron 2018
297
10

Resistance to autosomal dominant Alzheimer's disease in an APOE3 Christchurch homozygote: a case report.
Joseph F Arboleda-Velasquez, Francisco Lopera, Michael O'Hare, Santiago Delgado-Tirado, Claudia Marino, Natalia Chmielewska, Kahira L Saez-Torres, Dhanesh Amarnani, Aaron P Schultz, Reisa A Sperling,[...]. Nat Med 2019
151
10

APOE and Alzheimer disease: a major gene with semi-dominant inheritance.
E Genin, D Hannequin, D Wallon, K Sleegers, M Hiltunen, O Combarros, M J Bullido, S Engelborghs, P De Deyn, C Berr,[...]. Mol Psychiatry 2011
352
10

Human apoE isoforms differentially regulate brain amyloid-β peptide clearance.
Joseph M Castellano, Jungsu Kim, Floy R Stewart, Hong Jiang, Ronald B DeMattos, Bruce W Patterson, Anne M Fagan, John C Morris, Kwasi G Mawuenyega, Carlos Cruchaga,[...]. Sci Transl Med 2011
686
10

Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease.
D E Schmechel, A M Saunders, W J Strittmatter, B J Crain, C M Hulette, S H Joo, M A Pericak-Vance, D Goldgaber, A D Roses. Proc Natl Acad Sci U S A 1993
10

National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease.
Bradley T Hyman, Creighton H Phelps, Thomas G Beach, Eileen H Bigio, Nigel J Cairns, Maria C Carrillo, Dennis W Dickson, Charles Duyckaerts, Matthew P Frosch, Eliezer Masliah,[...]. Alzheimers Dement 2012
10

The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease.
Guy M McKhann, David S Knopman, Howard Chertkow, Bradley T Hyman, Clifford R Jack, Claudia H Kawas, William E Klunk, Walter J Koroshetz, Jennifer J Manly, Richard Mayeux,[...]. Alzheimers Dement 2011
10

TREM2 variants in Alzheimer's disease.
Rita Guerreiro, Aleksandra Wojtas, Jose Bras, Minerva Carrasquillo, Ekaterina Rogaeva, Elisa Majounie, Carlos Cruchaga, Celeste Sassi, John S K Kauwe, Steven Younkin,[...]. N Engl J Med 2013
10


Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease.
Reisa A Sperling, Paul S Aisen, Laurel A Beckett, David A Bennett, Suzanne Craft, Anne M Fagan, Takeshi Iwatsubo, Clifford R Jack, Jeffrey Kaye, Thomas J Montine,[...]. Alzheimers Dement 2011
9

Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study.
Eric M Reiman, Joseph F Arboleda-Velasquez, Yakeel T Quiroz, Matthew J Huentelman, Thomas G Beach, Richard J Caselli, Yinghua Chen, Yi Su, Amanda J Myers, John Hardy,[...]. Nat Commun 2020
107
9


APOE4 exacerbates synapse loss and neurodegeneration in Alzheimer's disease patient iPSC-derived cerebral organoids.
Jing Zhao, Yuan Fu, Yu Yamazaki, Yingxue Ren, Mary D Davis, Chia-Chen Liu, Wenyan Lu, Xue Wang, Kai Chen, Yesesri Cherukuri,[...]. Nat Commun 2020
49
16

Profile and regulation of apolipoprotein E (ApoE) expression in the CNS in mice with targeting of green fluorescent protein gene to the ApoE locus.
Qin Xu, Aubrey Bernardo, David Walker, Tiffany Kanegawa, Robert W Mahley, Yadong Huang. J Neurosci 2006
286
8

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease.
Denise Harold, Richard Abraham, Paul Hollingworth, Rebecca Sims, Amy Gerrish, Marian L Hamshere, Jaspreet Singh Pahwa, Valentina Moskvina, Kimberley Dowzell, Amy Williams,[...]. Nat Genet 2009
8


ApoE4 Accelerates Early Seeding of Amyloid Pathology.
Chia-Chen Liu, Na Zhao, Yuan Fu, Na Wang, Cynthia Linares, Chih-Wei Tsai, Guojun Bu. Neuron 2017
141
8


ApoE facilitates the microglial response to amyloid plaque pathology.
Jason D Ulrich, Tyler K Ulland, Thomas E Mahan, Sofie Nyström, K Peter Nilsson, Wilbur M Song, Yingyue Zhou, Mariska Reinartz, Seulah Choi, Hong Jiang,[...]. J Exp Med 2018
106
8


UK biobank: an open access resource for identifying the causes of a wide range of complex diseases of middle and old age.
Cathie Sudlow, John Gallacher, Naomi Allen, Valerie Beral, Paul Burton, John Danesh, Paul Downey, Paul Elliott, Jane Green, Martin Landray,[...]. PLoS Med 2015
8

APOE predicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging.
John C Morris, Catherine M Roe, Chengjie Xiong, Anne M Fagan, Alison M Goate, David M Holtzman, Mark A Mintun. Ann Neurol 2010
602
8


Gain of toxic apolipoprotein E4 effects in human iPSC-derived neurons is ameliorated by a small-molecule structure corrector.
Chengzhong Wang, Ramsey Najm, Qin Xu, Dah-Eun Jeong, David Walker, Maureen E Balestra, Seo Yeon Yoon, Heidi Yuan, Gang Li, Zachary A Miller,[...]. Nat Med 2018
146
7


Association of Apolipoprotein E ε4 With Medial Temporal Tau Independent of Amyloid-β.
Joseph Therriault, Andrea L Benedet, Tharick A Pascoal, Sulantha Mathotaarachchi, Mira Chamoun, Melissa Savard, Emilie Thomas, Min Su Kang, Firoza Lussier, Cecile Tissot,[...]. JAMA Neurol 2020
63
11

Apolipoprotein E: far more than a lipid transport protein.
R W Mahley, S C Rall. Annu Rev Genomics Hum Genet 2000
7

The amyloid hypothesis of Alzheimer's disease at 25 years.
Dennis J Selkoe, John Hardy. EMBO Mol Med 2016
7

Dementia prevention, intervention, and care: 2020 report of the Lancet Commission.
Gill Livingston, Jonathan Huntley, Andrew Sommerlad, David Ames, Clive Ballard, Sube Banerjee, Carol Brayne, Alistair Burns, Jiska Cohen-Mansfield, Claudia Cooper,[...]. Lancet 2020
7

APOE4 leads to blood-brain barrier dysfunction predicting cognitive decline.
Axel Montagne, Daniel A Nation, Abhay P Sagare, Giuseppe Barisano, Melanie D Sweeney, Ararat Chakhoyan, Maricarmen Pachicano, Elizabeth Joe, Amy R Nelson, Lina M D'Orazio,[...]. Nature 2020
296
7

Apolipoprotein E Is a Ligand for Triggering Receptor Expressed on Myeloid Cells 2 (TREM2).
Yuka Atagi, Chia-Chen Liu, Meghan M Painter, Xiao-Fen Chen, Christophe Verbeeck, Honghua Zheng, Xia Li, Rosa Rademakers, Silvia S Kang, Huaxi Xu,[...]. J Biol Chem 2015
244
7

Microglia drive APOE-dependent neurodegeneration in a tauopathy mouse model.
Yang Shi, Melissa Manis, Justin Long, Kairuo Wang, Patrick M Sullivan, Javier Remolina Serrano, Rosa Hoyle, David M Holtzman. J Exp Med 2019
107
7

Sex modifies the APOE-related risk of developing Alzheimer disease.
Andre Altmann, Lu Tian, Victor W Henderson, Michael D Greicius. Ann Neurol 2014
382
7

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.
Rebecca Sims, Sven J van der Lee, Adam C Naj, Céline Bellenguez, Nandini Badarinarayan, Johanna Jakobsdottir, Brian W Kunkle, Anne Boland, Rachel Raybould, Joshua C Bis,[...]. Nat Genet 2017
445
7


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.