A citation-based method for searching scientific literature

W S Pear, J C Aster, M L Scott, R P Hasserjian, B Soffer, J Sklar, D Baltimore. J Exp Med 1996
Times Cited: 558







List of co-cited articles
1206 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia.
Andrew P Weng, Adolfo A Ferrando, Woojoong Lee, John P Morris, Lewis B Silverman, Cheryll Sanchez-Irizarry, Stephen C Blacklow, A Thomas Look, Jon C Aster. Science 2004
76

TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms.
L W Ellisen, J Bird, D C West, A L Soreng, T C Reynolds, S D Smith, J Sklar. Cell 1991
32

FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors.
Jennifer O'Neil, Jonathan Grim, Peter Strack, Sudhir Rao, Deanne Tibbitts, Christopher Winter, James Hardwick, Markus Welcker, Jules P Meijerink, Rob Pieters,[...]. J Exp Med 2007
477
26

Deficient T cell fate specification in mice with an induced inactivation of Notch1.
F Radtke, A Wilson, G Stark, M Bauer, J van Meerwijk, H R MacDonald, M Aguet. Immunity 1999
25

Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia.
Teresa Palomero, Maria Luisa Sulis, Maria Cortina, Pedro J Real, Kelly Barnes, Maria Ciofani, Esther Caparros, Jean Buteau, Kristy Brown, Sherrie L Perkins,[...]. Nat Med 2007
643
24

c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma.
Andrew P Weng, John M Millholland, Yumi Yashiro-Ohtani, Marie Laure Arcangeli, Arthur Lau, Carol Wai, Cristina Del Bianco, Carlos G Rodriguez, Hong Sai, John Tobias,[...]. Genes Dev 2006
603
23

Leukemia-associated NOTCH1 alleles are weak tumor initiators but accelerate K-ras-initiated leukemia.
Mark Y Chiang, Lanwei Xu, Olga Shestova, Gavin Histen, Sarah L'heureux, Candice Romany, M Eden Childs, Phyllis A Gimotty, Jon C Aster, Warren S Pear. J Clin Invest 2008
163
23

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia.
Jinghui Zhang, Li Ding, Linda Holmfeldt, Gang Wu, Sue L Heatley, Debbie Payne-Turner, John Easton, Xiang Chen, Jianmin Wang, Michael Rusch,[...]. Nature 2012
22

Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia.
Adolfo A Ferrando, Donna S Neuberg, Jane Staunton, Mignon L Loh, Christine Huard, Susana C Raimondi, Fred G Behm, Ching Hon Pui, James R Downing, D Gary Gilliland,[...]. Cancer Cell 2002
766
21

The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia.
Benjamin J Thompson, Silvia Buonamici, Maria Luisa Sulis, Teresa Palomero, Tomas Vilimas, Giuseppe Basso, Adolfo Ferrando, Iannis Aifantis. J Exp Med 2007
339
20

Integrated transcript and genome analyses reveal NKX2-1 and MEF2C as potential oncogenes in T cell acute lymphoblastic leukemia.
Irene Homminga, Rob Pieters, Anton W Langerak, Johan J de Rooi, Andrew Stubbs, Monique Verstegen, Maartje Vuerhard, Jessica Buijs-Gladdines, Clarissa Kooi, Petra Klous,[...]. Cancer Cell 2011
236
19

NOTCH1-RBPJ complexes drive target gene expression through dynamic interactions with superenhancers.
Hongfang Wang, Chongzhi Zang, Len Taing, Kelly L Arnett, Yinling Joey Wong, Warren S Pear, Stephen C Blacklow, X Shirley Liu, Jon C Aster. Proc Natl Acad Sci U S A 2014
140
19

The molecular basis of T cell acute lymphoblastic leukemia.
Pieter Van Vlierberghe, Adolfo Ferrando. J Clin Invest 2012
294
18

A NOTCH1-driven MYC enhancer promotes T cell development, transformation and acute lymphoblastic leukemia.
Daniel Herranz, Alberto Ambesi-Impiombato, Teresa Palomero, Stephanie A Schnell, Laura Belver, Agnieszka A Wendorff, Luyao Xu, Mireia Castillo-Martin, David Llobet-Navás, Carlos Cordon-Cardo,[...]. Nat Med 2014
217
18

NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth.
Teresa Palomero, Wei Keat Lim, Duncan T Odom, Maria Luisa Sulis, Pedro J Real, Adam Margolin, Kelly C Barnes, Jennifer O'Neil, Donna Neuberg, Andrew P Weng,[...]. Proc Natl Acad Sci U S A 2006
569
18


Notch1 expression in early lymphopoiesis influences B versus T lineage determination.
J C Pui, D Allman, L Xu, S DeRocco, F G Karnell, S Bakkour, J Y Lee, T Kadesch, R R Hardy, J C Aster,[...]. Immunity 1999
735
17

High-level IGF1R expression is required for leukemia-initiating cell activity in T-ALL and is supported by Notch signaling.
Hind Medyouf, Samuel Gusscott, Hongfang Wang, Jen-Chieh Tseng, Carol Wai, Oksana Nemirovsky, Andreas Trumpp, Francoise Pflumio, Joan Carboni, Marco Gottardis,[...]. J Exp Med 2011
116
16

NOTCH is a key regulator of human T-cell acute leukemia initiating cell activity.
Florence Armstrong, Philippe Brunet de la Grange, Bastien Gerby, Marie-Christine Rouyez, Julien Calvo, Michaéla Fontenay, Nicolas Boissel, Hervé Dombret, André Baruchel, Judith Landman-Parker,[...]. Blood 2009
112
16

Notch1 contributes to mouse T-cell leukemia by directly inducing the expression of c-myc.
Vishva Mitra Sharma, Jennifer A Calvo, Kyle M Draheim, Leslie A Cunningham, Nicole Hermance, Levi Beverly, Veena Krishnamoorthy, Manoj Bhasin, Anthony J Capobianco, Michelle A Kelliher. Mol Cell Biol 2006
203
16

Growth suppression of pre-T acute lymphoblastic leukemia cells by inhibition of notch signaling.
Andrew P Weng, Yunsun Nam, Michael S Wolfe, Warren S Pear, James D Griffin, Stephen C Blacklow, Jon C Aster. Mol Cell Biol 2003
303
15

The genomic landscape of pediatric and young adult T-lineage acute lymphoblastic leukemia.
Yu Liu, John Easton, Ying Shao, Jamie Maciaszek, Zhaoming Wang, Mark R Wilkinson, Kelly McCastlain, Michael Edmonson, Stanley B Pounds, Lei Shi,[...]. Nat Genet 2017
332
15

Acute lymphoblastic leukaemia.
Ching-Hon Pui, Leslie L Robison, A Thomas Look. Lancet 2008
931
14

Leukemia-associated mutations within the NOTCH1 heterodimerization domain fall into at least two distinct mechanistic classes.
Michael J Malecki, Cheryll Sanchez-Irizarry, Jennifer L Mitchell, Gavin Histen, Mina L Xu, Jon C Aster, Stephen C Blacklow. Mol Cell Biol 2006
178
14

Notch signaling: cell fate control and signal integration in development.
S Artavanis-Tsakonas, M D Rand, R J Lake. Science 1999
14

Long-range enhancer activity determines Myc sensitivity to Notch inhibitors in T cell leukemia.
Yumi Yashiro-Ohtani, Hongfang Wang, Chongzhi Zang, Kelly L Arnett, Will Bailis, Yugong Ho, Birgit Knoechel, Claudia Lanauze, Lumena Louis, Katherine S Forsyth,[...]. Proc Natl Acad Sci U S A 2014
106
13

CUTLL1, a novel human T-cell lymphoma cell line with t(7;9) rearrangement, aberrant NOTCH1 activation and high sensitivity to gamma-secretase inhibitors.
T Palomero, K C Barnes, P J Real, J L Glade Bender, M L Sulis, V V Murty, A I Colovai, M Balbin, A A Ferrando. Leukemia 2006
108
13

Genome-wide analysis reveals conserved and divergent features of Notch1/RBPJ binding in human and murine T-lymphoblastic leukemia cells.
Hongfang Wang, James Zou, Bo Zhao, Eric Johannsen, Todd Ashworth, Hoifung Wong, Warren S Pear, Jonathan Schug, Stephen C Blacklow, Kelly L Arnett,[...]. Proc Natl Acad Sci U S A 2011
172
13

Exome sequencing identifies mutation in CNOT3 and ribosomal genes RPL5 and RPL10 in T-cell acute lymphoblastic leukemia.
Kim De Keersmaecker, Zeynep Kalender Atak, Ning Li, Carmen Vicente, Stephanie Patchett, Tiziana Girardi, Valentina Gianfelici, Ellen Geerdens, Emmanuelle Clappier, Michaël Porcu,[...]. Nat Genet 2013
260
12

Modeling T-cell acute lymphoblastic leukemia induced by the SCL and LMO1 oncogenes.
Mathieu Tremblay, Cédric S Tremblay, Sabine Herblot, Peter D Aplan, Josée Hébert, Claude Perreault, Trang Hoang. Genes Dev 2010
80
15

CSL-MAML-dependent Notch1 signaling controls T lineage-specific IL-7R{alpha} gene expression in early human thymopoiesis and leukemia.
Sara González-García, Marina García-Peydró, Enrique Martín-Gayo, Esteban Ballestar, Manel Esteller, Rafael Bornstein, José Luis de la Pompa, Adolfo A Ferrando, María L Toribio. J Exp Med 2009
103
12

Gamma-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia.
Pedro J Real, Valeria Tosello, Teresa Palomero, Mireia Castillo, Eva Hernando, Elisa de Stanchina, Maria Luisa Sulis, Kelly Barnes, Catherine Sawai, Irene Homminga,[...]. Nat Med 2009
313
12

High frequency of PTEN, PI3K, and AKT abnormalities in T-cell acute lymphoblastic leukemia.
Alejandro Gutierrez, Takaomi Sanda, Ruta Grebliunaite, Arkaitz Carracedo, Leonardo Salmena, Yebin Ahn, Suzanne Dahlberg, Donna Neuberg, Lisa A Moreau, Stuart S Winter,[...]. Blood 2009
311
12

Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia.
Priscila P Zenatti, Daniel Ribeiro, Wenqing Li, Linda Zuurbier, Milene C Silva, Maddalena Paganin, Julia Tritapoe, Julie A Hixon, André B Silveira, Bruno A Cardoso,[...]. Nat Genet 2011
253
12

The genetics and mechanisms of T cell acute lymphoblastic leukaemia.
Laura Belver, Adolfo Ferrando. Nat Rev Cancer 2016
172
12

HOXA genes are included in genetic and biologic networks defining human acute T-cell leukemia (T-ALL).
Jean Soulier, Emmanuelle Clappier, Jean-Michel Cayuela, Armelle Regnault, Marina García-Peydró, Hervé Dombret, André Baruchel, Maria-Luisa Toribio, François Sigaux. Blood 2005
251
11

Core transcriptional regulatory circuit controlled by the TAL1 complex in human T cell acute lymphoblastic leukemia.
Takaomi Sanda, Lee N Lawton, M Inmaculada Barrasa, Zi Peng Fan, Holger Kohlhammer, Alejandro Gutierrez, Wenxue Ma, Jessica Tatarek, Yebin Ahn, Michelle A Kelliher,[...]. Cancer Cell 2012
173
11

The ubiquitin ligase FBXW7 modulates leukemia-initiating cell activity by regulating MYC stability.
Bryan King, Thomas Trimarchi, Linsey Reavie, Luyao Xu, Jasper Mullenders, Panagiotis Ntziachristos, Beatriz Aranda-Orgilles, Arianne Perez-Garcia, Junwei Shi, Christopher Vakoc,[...]. Cell 2013
197
11

Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia.
Xose S Puente, Magda Pinyol, Víctor Quesada, Laura Conde, Gonzalo R Ordóñez, Neus Villamor, Georgia Escaramis, Pedro Jares, Sílvia Beà, Marcos González-Díaz,[...]. Nature 2011
11

The Notch/Hes1 pathway sustains NF-κB activation through CYLD repression in T cell leukemia.
Lluis Espinosa, Severine Cathelin, Teresa D'Altri, Thomas Trimarchi, Alexander Statnikov, Jordi Guiu, Veronica Rodilla, Julia Inglés-Esteve, Josep Nomdedeu, Beatriz Bellosillo,[...]. Cancer Cell 2010
194
11

Molecular pathogenesis of T-cell leukaemia and lymphoma.
Iannis Aifantis, Elizabeth Raetz, Silvia Buonamici. Nat Rev Immunol 2008
291
11

NOTCH1 promotes T cell leukemia-initiating activity by RUNX-mediated regulation of PKC-θ and reactive oxygen species.
Vincenzo Giambra, Christopher R Jenkins, Hongfang Wang, Sonya H Lam, Olena O Shevchuk, Oksana Nemirovsky, Carol Wai, Sam Gusscott, Mark Y Chiang, Jon C Aster,[...]. Nat Med 2012
59
18

Notch1 inhibition targets the leukemia-initiating cells in a Tal1/Lmo2 mouse model of T-ALL.
Jessica Tatarek, Kathleen Cullion, Todd Ashworth, Rachel Gerstein, Jon C Aster, Michelle A Kelliher. Blood 2011
67
16

CXCR4 Is Required for Leukemia-Initiating Cell Activity in T Cell Acute Lymphoblastic Leukemia.
Diana Passaro, Marta Irigoyen, Claire Catherinet, Stéphanie Gachet, Cindy Da Costa De Jesus, Charlène Lasgi, Christine Tran Quang, Jacques Ghysdael. Cancer Cell 2015
101
11

CXCL12-Producing Vascular Endothelial Niches Control Acute T Cell Leukemia Maintenance.
Lauren A Pitt, Anastasia N Tikhonova, Hai Hu, Thomas Trimarchi, Bryan King, Yixiao Gong, Marta Sanchez-Martin, Aris Tsirigos, Dan R Littman, Adolfo A Ferrando,[...]. Cancer Cell 2015
150
11

Therapeutic antibody targeting of individual Notch receptors.
Yan Wu, Carol Cain-Hom, Lisa Choy, Thijs J Hagenbeek, Gladys P de Leon, Yongmei Chen, David Finkle, Rayna Venook, Xiumin Wu, John Ridgway,[...]. Nature 2010
500
11

Early T-cell precursor leukaemia: a subtype of very high-risk acute lymphoblastic leukaemia.
Elaine Coustan-Smith, Charles G Mullighan, Mihaela Onciu, Frederick G Behm, Susana C Raimondi, Deqing Pei, Cheng Cheng, Xiaoping Su, Jeffrey E Rubnitz, Giuseppe Basso,[...]. Lancet Oncol 2009
518
11

Hes1 is a critical but context-dependent mediator of canonical Notch signaling in lymphocyte development and transformation.
Agnieszka A Wendorff, Ute Koch, F Thomas Wunderlich, Silvia Wirth, Christelle Dubey, Jens C Brüning, H Robson MacDonald, Freddy Radtke. Immunity 2010
92
10

Essential roles for ankyrin repeat and transactivation domains in induction of T-cell leukemia by notch1.
J C Aster, L Xu, F G Karnell, V Patriub, J C Pui, W S Pear. Mol Cell Biol 2000
233
10

Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells.
Johan H van Es, Marielle E van Gijn, Orbicia Riccio, Maaike van den Born, Marc Vooijs, Harry Begthel, Miranda Cozijnsen, Sylvie Robine, Doug J Winton, Freddy Radtke,[...]. Nature 2005
10


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.