A citation-based method for searching scientific literature

C Chiang, Y Litingtung, E Lee, K E Young, J L Corden, H Westphal, P A Beachy. Nature 1996
Times Cited: 2320







List of co-cited articles
1197 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity.
Y Echelard, D J Epstein, B St-Jacques, L Shen, J Mohler, J A McMahon, A P McMahon. Cell 1993
17

Hedgehog signalling in the mouse requires intraflagellar transport proteins.
Danwei Huangfu, Aimin Liu, Andrew S Rakeman, Noel S Murcia, Lee Niswander, Kathryn V Anderson. Nature 2003
957
15


Mutations in the human Sonic Hedgehog gene cause holoprosencephaly.
E Roessler, E Belloni, K Gaudenz, P Jay, P Berta, S W Scherer, L C Tsui, M Muenke. Nat Genet 1996
841
12

Patched1 regulates hedgehog signaling at the primary cilium.
Rajat Rohatgi, Ljiljana Milenkovic, Matthew P Scott. Science 2007
942
12

The graded response to Sonic Hedgehog depends on cilia architecture.
Tamara Caspary, Christine E Larkins, Kathryn V Anderson. Dev Cell 2007
488
11

The teratogenic effects of prenatal ethanol exposure are exacerbated by Sonic Hedgehog or GLI2 haploinsufficiency in the mouse.
Henry W Kietzman, Joshua L Everson, Kathleen K Sulik, Robert J Lipinski. PLoS One 2014
74
13

Altered neural cell fates and medulloblastoma in mouse patched mutants.
L V Goodrich, L Milenković, K M Higgins, M P Scott. Science 1997
10

Vertebrate Smoothened functions at the primary cilium.
Kevin C Corbit, Pia Aanstad, Veena Singla, Andrew R Norman, Didier Y R Stainier, Jeremy F Reiter. Nature 2005
993
10

Cilia and Hedgehog responsiveness in the mouse.
Danwei Huangfu, Kathryn V Anderson. Proc Natl Acad Sci U S A 2005
591
10


The mechanisms of Hedgehog signalling and its roles in development and disease.
James Briscoe, Pascal P Thérond. Nat Rev Mol Cell Biol 2013
945
9

Sonic hedgehog mediates the polarizing activity of the ZPA.
R D Riddle, R L Johnson, E Laufer, C Tabin. Cell 1993
9

The primary cilium: a signalling centre during vertebrate development.
Sarah C Goetz, Kathryn V Anderson. Nat Rev Genet 2010
9

Interpretation of the sonic hedgehog morphogen gradient by a temporal adaptation mechanism.
Eric Dessaud, Lin Lin Yang, Katy Hill, Barny Cox, Fausto Ulloa, Ana Ribeiro, Anita Mynett, Bennett G Novitch, James Briscoe. Nature 2007
363
9

ARL13B regulates Sonic hedgehog signaling from outside primary cilia.
Eduardo D Gigante, Megan R Taylor, Anna A Ivanova, Richard A Kahn, Tamara Caspary. Elife 2020
18
50

Mutations affecting segment number and polarity in Drosophila.
C Nüsslein-Volhard, E Wieschaus. Nature 1980
9

The molecular genetics of holoprosencephaly.
Erich Roessler, Maximilian Muenke. Am J Med Genet C Semin Med Genet 2010
155
8

Hedgehog signaling in the neural crest cells regulates the patterning and growth of facial primordia.
Juhee Jeong, Junhao Mao, Toyoaki Tenzen, Andreas H Kottmann, Andrew P McMahon. Genes Dev 2004
416
8

Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened.
James K Chen, Jussi Taipale, Michael K Cooper, Philip A Beachy. Genes Dev 2002
8


The ciliary G-protein-coupled receptor Gpr161 negatively regulates the Sonic hedgehog pathway via cAMP signaling.
Saikat Mukhopadhyay, Xiaohui Wen, Navneet Ratti, Alexander Loktev, Linda Rangell, Suzie J Scales, Peter K Jackson. Cell 2013
263
8

Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord.
H Roelink, A Augsburger, J Heemskerk, V Korzh, S Norlin, A Ruiz i Altaba, Y Tanabe, M Placzek, T Edlund, T M Jessell. Cell 1994
743
8

Primary Cilia and Mammalian Hedgehog Signaling.
Fiona Bangs, Kathryn V Anderson. Cold Spring Harb Perspect Biol 2017
225
8

The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins.
Eric W Humke, Karolin V Dorn, Ljiljana Milenkovic, Matthew P Scott, Rajat Rohatgi. Genes Dev 2010
303
8

Gli protein activity is controlled by multisite phosphorylation in vertebrate Hedgehog signaling.
Pawel Niewiadomski, Jennifer H Kong, Robert Ahrends, Yan Ma, Eric W Humke, Sohini Khan, Mary N Teruel, Bennett G Novitch, Rajat Rohatgi. Cell Rep 2014
133
7

Dorsal-ventral patterning of the spinal cord requires Gli3 transcriptional repressor activity.
Madelen Persson, Despina Stamataki, Pascal te Welscher, Elisabet Andersson, Jens Böse, Ulrich Rüther, Johan Ericson, James Briscoe. Genes Dev 2002
238
7


Kinetics of hedgehog-dependent full-length Gli3 accumulation in primary cilia and subsequent degradation.
Xiaohui Wen, Cary K Lai, Marie Evangelista, Jo-Anne Hongo, Frederic J de Sauvage, Suzie J Scales. Mol Cell Biol 2010
169
7

Self-organizing optic-cup morphogenesis in three-dimensional culture.
Mototsugu Eiraku, Nozomu Takata, Hiroki Ishibashi, Masako Kawada, Eriko Sakakura, Satoru Okuda, Kiyotoshi Sekiguchi, Taiji Adachi, Yoshiki Sasai. Nature 2011
6

Genotypic and phenotypic analysis of 396 individuals with mutations in Sonic Hedgehog.
Benjamin D Solomon, Kelly A Bear, Adrian Wyllie, Amelia A Keaton, Christele Dubourg, Veronique David, Sandra Mercier, Sylvie Odent, Ute Hehr, Aimee Paulussen,[...]. J Med Genet 2012
51
11



Mouse Dispatched homolog1 is required for long-range, but not juxtacrine, Hh signaling.
Tamara Caspary, María Jesús García-García, Danwei Huangfu, Jonathan T Eggenschwiler, Michael R Wyler, Andrew S Rakeman, Heather L Alcorn, Kathryn V Anderson. Curr Biol 2002
123
6


Fiji: an open-source platform for biological-image analysis.
Johannes Schindelin, Ignacio Arganda-Carreras, Erwin Frise, Verena Kaynig, Mark Longair, Tobias Pietzsch, Stephan Preibisch, Curtis Rueden, Stephan Saalfeld, Benjamin Schmid,[...]. Nat Methods 2012
6

Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function.
Courtney J Haycraft, Boglarka Banizs, Yesim Aydin-Son, Qihong Zhang, Edward J Michaud, Bradley K Yoder. PLoS Genet 2005
638
6

Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway.
Jessica Svärd, Karin Heby-Henricson, Madelen Persson-Lek, Björn Rozell, Matthias Lauth, Asa Bergström, Johan Ericson, Rune Toftgård, Stephan Teglund. Dev Cell 2006
348
6

A gradient of Gli activity mediates graded Sonic Hedgehog signaling in the neural tube.
Despina Stamataki, Fausto Ulloa, Stavroula V Tsoni, Anita Mynett, James Briscoe. Genes Dev 2005
202
6


Activating Smoothened mutations in sporadic basal-cell carcinoma.
J Xie, M Murone, S M Luoh, A Ryan, Q Gu, C Zhang, J M Bonifas, C W Lam, M Hynes, A Goddard,[...]. Nature 1998
982
6



Hedgehog: functions and mechanisms.
Markku Varjosalo, Jussi Taipale. Genes Dev 2008
819
6

Molecular interactions coordinating the development of the forebrain and face.
Ralph S Marcucio, Dwight R Cordero, Diane Hu, Jill A Helms. Dev Biol 2005
162
6

Shh and Gli3 are dispensable for limb skeleton formation but regulate digit number and identity.
Ying Litingtung, Randall D Dahn, Yina Li, John F Fallon, Chin Chiang. Nature 2002
425
6

Mouse Shh is required for prechordal plate maintenance during brain and craniofacial morphogenesis.
Kazushi Aoto, Yayoi Shikata, Hajime Imai, Daisuke Matsumaru, Tomoyuki Tokunaga, Seiji Shioda, Gen Yamada, Jun Motoyama. Dev Biol 2009
60
10

Sonic Hedgehog-induced activation of the Gli1 promoter is mediated by GLI3.
P Dai, H Akimaru, Y Tanaka, T Maekawa, M Nakafuku, S Ishii. J Biol Chem 1999
419
6

Essential function of Gli2 and Gli3 in the formation of lung, trachea and oesophagus.
J Motoyama, J Liu, R Mo, Q Ding, M Post, C C Hui. Nat Genet 1998
403
6

Biochemical mechanisms of vertebrate hedgehog signaling.
Jennifer H Kong, Christian Siebold, Rajat Rohatgi. Development 2019
76
7


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.