A citation-based method for searching scientific literature

L Mangiarini, K Sathasivam, M Seller, B Cozens, A Harper, C Hetherington, M Lawton, Y Trottier, H Lehrach, S W Davies, G P Bates. Cell 1996
Times Cited: 2342







List of co-cited articles
1282 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity



Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease.
Elizabeth J Slow, Jeremy van Raamsdonk, Daniel Rogers, Sarah H Coleman, Rona K Graham, Yu Deng, Rosemary Oh, Nagat Bissada, Sazzad M Hossain, Yu-Zhou Yang,[...]. Hum Mol Genet 2003
585
20

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain.
M DiFiglia, E Sapp, K O Chase, S W Davies, G P Bates, J P Vonsattel, N Aronin. Science 1997
19

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation.
S W Davies, M Turmaine, B A Cozens, M DiFiglia, A H Sharp, C A Ross, E Scherzinger, E E Wanker, L Mangiarini, G P Bates. Cell 1997
19

The Biology of Huntingtin.
Frédéric Saudou, Sandrine Humbert. Neuron 2016
381
18

Comprehensive behavioral and molecular characterization of a new knock-in mouse model of Huntington's disease: zQ175.
Liliana B Menalled, Andrea E Kudwa, Sam Miller, Jon Fitzpatrick, Judy Watson-Johnson, Nicole Keating, Melinda Ruiz, Richard Mushlin, William Alosio, Kristi McConnell,[...]. PLoS One 2012
232
18

Huntington disease.
Gillian P Bates, Ray Dorsey, James F Gusella, Michael R Hayden, Chris Kay, Blair R Leavitt, Martha Nance, Christopher A Ross, Rachael I Scahill, Ronald Wetzel,[...]. Nat Rev Dis Primers 2015
604
17

Full-length human mutant huntingtin with a stable polyglutamine repeat can elicit progressive and selective neuropathogenesis in BACHD mice.
Michelle Gray, Dyna I Shirasaki, Carlos Cepeda, Véronique M André, Brian Wilburn, Xiao-Hong Lu, Jifang Tao, Irene Yamazaki, Shi-Hua Li, Yi E Sun,[...]. J Neurosci 2008
439
17

Neuropathological classification of Huntington's disease.
J P Vonsattel, R H Myers, T J Stevens, R J Ferrante, E D Bird, E P Richardson. J Neuropathol Exp Neurol 1985
16

Time course of early motor and neuropathological anomalies in a knock-in mouse model of Huntington's disease with 140 CAG repeats.
Liliana B Menalled, Jessica D Sison, Ioannis Dragatsis, Scott Zeitlin, Marie-Françoise Chesselet. J Comp Neurol 2003
336
14

Huntington's disease: from molecular pathogenesis to clinical treatment.
Christopher A Ross, Sarah J Tabrizi. Lancet Neurol 2011
925
13

Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease.
Kirupa Sathasivam, Andreas Neueder, Theresa A Gipson, Christian Landles, Agnesska C Benjamin, Marie K Bondulich, Donna L Smith, Richard L M Faull, Raymund A C Roos, David Howland,[...]. Proc Natl Acad Sci U S A 2013
273
12

Characterization of neurophysiological and behavioral changes, MRI brain volumetry and 1H MRS in zQ175 knock-in mouse model of Huntington's disease.
Taneli Heikkinen, Kimmo Lehtimäki, Nina Vartiainen, Jukka Puoliväli, Susan J Hendricks, Jack R Glaser, Amyaouch Bradaia, Kristian Wadel, Chrystelle Touller, Outi Kontkanen,[...]. PLoS One 2012
147
12

Huntington disease.
J P Vonsattel, M DiFiglia. J Neuropathol Exp Neurol 1998
12


Integrated genomics and proteomics define huntingtin CAG length-dependent networks in mice.
Peter Langfelder, Jeffrey P Cantle, Doxa Chatzopoulou, Nan Wang, Fuying Gao, Ismael Al-Ramahi, Xiao-Hong Lu, Eliana Marisa Ramos, Karla El-Zein, Yining Zhao,[...]. Nat Neurosci 2016
189
11

Huntington's disease.
Francis O Walker. Lancet 2007
11

Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin.
G Schilling, M W Becher, A H Sharp, H A Jinnah, K Duan, J A Kotzuk, H H Slunt, T Ratovitski, J K Cooper, N A Jenkins,[...]. Hum Mol Genet 1999
583
11

Targeting Huntingtin Expression in Patients with Huntington's Disease.
Sarah J Tabrizi, Blair R Leavitt, G Bernhard Landwehrmeyer, Edward J Wild, Carsten Saft, Roger A Barker, Nick F Blair, David Craufurd, Josef Priller, Hugh Rickards,[...]. N Engl J Med 2019
288
10

Neurological abnormalities in a knock-in mouse model of Huntington's disease.
C H Lin, S Tallaksen-Greene, W M Chien, J A Cearley, W S Jackson, A B Crouse, S Ren, X J Li, R L Albin, P J Detloff. Hum Mol Genet 2001
442
10


A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration.
J G Hodgson, N Agopyan, C A Gutekunst, B R Leavitt, F LePiane, R Singaraja, D J Smith, N Bissada, K McCutcheon, J Nasir,[...]. Neuron 1999
633
9

Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo.
E Scherzinger, R Lurz, M Turmaine, L Mangiarini, B Hollenbach, R Hasenbank, G P Bates, S W Davies, H Lehrach, E E Wanker. Cell 1997
9

Polyglutamine disruption of the huntingtin exon 1 N terminus triggers a complex aggregation mechanism.
Ashwani K Thakur, Murali Jayaraman, Rakesh Mishra, Monika Thakur, Veronique M Chellgren, In-Ja L Byeon, Dalaver H Anjum, Ravindra Kodali, Trevor P Creamer, James F Conway,[...]. Nat Struct Mol Biol 2009
308
9

The corticostriatal pathway in Huntington's disease.
Carlos Cepeda, Nanping Wu, Véronique M André, Damian M Cummings, Michael S Levine. Prog Neurobiol 2007
232
9

In Situ Architecture and Cellular Interactions of PolyQ Inclusions.
Felix J B Bäuerlein, Itika Saha, Archana Mishra, Maria Kalemanov, Antonio Martínez-Sánchez, Rüdiger Klein, Irina Dudanova, Mark S Hipp, F Ulrich Hartl, Wolfgang Baumeister,[...]. Cell 2017
146
9

Polyglutamine Repeats in Neurodegenerative Diseases.
Andrew P Lieberman, Vikram G Shakkottai, Roger L Albin. Annu Rev Pathol 2019
93
8

Systematic behavioral evaluation of Huntington's disease transgenic and knock-in mouse models.
Liliana Menalled, Bassem F El-Khodor, Monica Patry, Mayte Suárez-Fariñas, Samantha J Orenstein, Benjamin Zahasky, Christina Leahy, Vanessa Wheeler, X William Yang, Marcy MacDonald,[...]. Neurobiol Dis 2009
227
8

The relationship between trinucleotide (CAG) repeat length and clinical features of Huntington's disease.
S E Andrew, Y P Goldberg, B Kremer, H Telenius, J Theilmann, S Adam, E Starr, F Squitieri, B Lin, M A Kalchman. Nat Genet 1993
807
8

Trinucleotide repeat length instability and age of onset in Huntington's disease.
M Duyao, C Ambrose, R Myers, A Novelletto, F Persichetti, M Frontali, S Folstein, C Ross, M Franz, M Abbott. Nat Genet 1993
818
8

Electrophysiological and morphological changes in striatal spiny neurons in R6/2 Huntington's disease transgenic mice.
G J Klapstein, R S Fisher, H Zanjani, C Cepeda, E S Jokel, M F Chesselet, M S Levine. J Neurophysiol 2001
246
7

N-terminal Huntingtin (Htt) phosphorylation is a molecular switch regulating Htt aggregation, helical conformation, internalization, and nuclear targeting.
Sean M DeGuire, Francesco S Ruggeri, Mohamed-Bilal Fares, Anass Chiki, Urszula Cendrowska, Giovanni Dietler, Hilal A Lashuel. J Biol Chem 2018
35
20

Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: implications for Huntington's disease pathology.
E Scherzinger, A Sittler, K Schweiger, V Heiser, R Lurz, R Hasenbank, G P Bates, H Lehrach, E E Wanker. Proc Natl Acad Sci U S A 1999
526
7

Characterization of progressive motor deficits in mice transgenic for the human Huntington's disease mutation.
R J Carter, L A Lione, T Humby, L Mangiarini, A Mahal, G P Bates, S B Dunnett, A J Morton. J Neurosci 1999
696
7

Spatiotemporal Proteomic Profiling of Huntington's Disease Inclusions Reveals Widespread Loss of Protein Function.
Fabian Hosp, Sara Gutiérrez-Ángel, Martin H Schaefer, Jürgen Cox, Felix Meissner, Mark S Hipp, F-Ulrich Hartl, Rüdiger Klein, Irina Dudanova, Matthias Mann. Cell Rep 2017
62
11

Choosing an animal model for the study of Huntington's disease.
Mahmoud A Pouladi, A Jennifer Morton, Michael R Hayden. Nat Rev Neurosci 2013
213
7

Huntingtin Lowering Strategies for Disease Modification in Huntington's Disease.
Sarah J Tabrizi, Rhia Ghosh, Blair R Leavitt. Neuron 2019
81
8

Nuclear and neuropil aggregates in Huntington's disease: relationship to neuropathology.
C A Gutekunst, S H Li, H Yi, J S Mulroy, S Kuemmerle, R Jones, D Rye, R J Ferrante, S M Hersch, X J Li. J Neurosci 1999
620
7

Proteolysis of mutant huntingtin produces an exon 1 fragment that accumulates as an aggregated protein in neuronal nuclei in Huntington disease.
Christian Landles, Kirupa Sathasivam, Andreas Weiss, Ben Woodman, Hilary Moffitt, Steve Finkbeiner, Banghua Sun, Juliette Gafni, Lisa M Ellerby, Yvon Trottier,[...]. J Biol Chem 2010
217
7

RAN Translation in Huntington Disease.
Monica Bañez-Coronel, Fatma Ayhan, Alex D Tarabochia, Tao Zu, Barbara A Perez, Solaleh Khoramian Tusi, Olga Pletnikova, David R Borchelt, Christopher A Ross, Russell L Margolis,[...]. Neuron 2015
190
7

Knock-in mouse models of Huntington's disease.
Liliana B Menalled. NeuroRx 2005
90
7

Huntington's disease: a clinical review.
P McColgan, S J Tabrizi. Eur J Neurol 2018
297
7


Mouse Models of Huntington's Disease.
Pamela P Farshim, Gillian P Bates. Methods Mol Biol 2018
30
23

The incidence and prevalence of Huntington's disease: a systematic review and meta-analysis.
Tamara Pringsheim, Katie Wiltshire, Lundy Day, Jonathan Dykeman, Thomas Steeves, Nathalie Jette. Mov Disord 2012
284
6

Polyglutamine domain flexibility mediates the proximity between flanking sequences in huntingtin.
Nicholas Stephane Caron, Carly Robyn Desmond, Jianrun Xia, Ray Truant. Proc Natl Acad Sci U S A 2013
93
6

IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome.
Leslie Michels Thompson, Charity T Aiken, Linda S Kaltenbach, Namita Agrawal, Katalin Illes, Ali Khoshnan, Marta Martinez-Vincente, Montserrat Arrasate, Jacqueline Gire O'Rourke, Hasan Khashwji,[...]. J Cell Biol 2009
254
6

The emerging role of the first 17 amino acids of huntingtin in Huntington's disease.
James R Arndt, Maxmore Chaibva, Justin Legleiter. Biomol Concepts 2015
39
15

The pathogenic exon 1 HTT protein is produced by incomplete splicing in Huntington's disease patients.
Andreas Neueder, Christian Landles, Rhia Ghosh, David Howland, Richard H Myers, Richard L M Faull, Sarah J Tabrizi, Gillian P Bates. Sci Rep 2017
76
7

Potential function for the Huntingtin protein as a scaffold for selective autophagy.
Joseph Ochaba, Tamás Lukacsovich, George Csikos, Shuqiu Zheng, Julia Margulis, Lisa Salazar, Kai Mao, Alice L Lau, Sylvia Y Yeung, Sandrine Humbert,[...]. Proc Natl Acad Sci U S A 2014
166
6


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.