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Times Cited: 2256
Times Cited
Times Co-cited
Similarity
39
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M DiFiglia, E Sapp, K O Chase, S W Davies, G P Bates, J P Vonsattel, N Aronin. Science 1997
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Comprehensive behavioral and molecular characterization of a new knock-in mouse model of Huntington's disease: zQ175.
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Full-length human mutant huntingtin with a stable polyglutamine repeat can elicit progressive and selective neuropathogenesis in BACHD mice.
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Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation.
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Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease.
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A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease.
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Molecular mechanisms and potential therapeutical targets in Huntington's disease.
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Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease.
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Systematic behavioral evaluation of Huntington's disease transgenic and knock-in mouse models.
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Integrated genomics and proteomics define huntingtin CAG length-dependent networks in mice.
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Neurological abnormalities in a knock-in mouse model of Huntington's disease.
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Chronology of behavioral symptoms and neuropathological sequela in R6/2 Huntington's disease transgenic mice.
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Characterization of neurophysiological and behavioral changes, MRI brain volumetry and 1H MRS in zQ175 knock-in mouse model of Huntington's disease.
Taneli Heikkinen, Kimmo Lehtimäki, Nina Vartiainen, Jukka Puoliväli, Susan J Hendricks, Jack R Glaser, Amyaouch Bradaia, Kristian Wadel, Chrystelle Touller, Outi Kontkanen,[...]. PLoS One 2012
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The pathogenic exon 1 HTT protein is produced by incomplete splicing in Huntington's disease patients.
Andreas Neueder, Christian Landles, Rhia Ghosh, David Howland, Richard H Myers, Richard L M Faull, Sarah J Tabrizi, Gillian P Bates. Sci Rep 2017
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Time course of early motor and neuropathological anomalies in a knock-in mouse model of Huntington's disease with 140 CAG repeats.
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Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin.
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Somatic expansion of the Huntington's disease CAG repeat in the brain is associated with an earlier age of disease onset.
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Mismatch repair genes Mlh1 and Mlh3 modify CAG instability in Huntington's disease mice: genome-wide and candidate approaches.
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Triplet repeat mutation length gains correlate with cell-type specific vulnerability in Huntington disease brain.
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Dominant phenotypes produced by the HD mutation in STHdh(Q111) striatal cells.
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Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo.
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The use of the R6 transgenic mouse models of Huntington's disease in attempts to develop novel therapeutic strategies.
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Spatiotemporal Proteomic Profiling of Huntington's Disease Inclusions Reveals Widespread Loss of Protein Function.
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The corticostriatal pathway in Huntington's disease.
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Instability of highly expanded CAG repeats in mice transgenic for the Huntington's disease mutation.
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Identification of genetic variants associated with Huntington's disease progression: a genome-wide association study.
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Molecular analysis of juvenile Huntington disease: the major influence on (CAG)n repeat length is the sex of the affected parent.
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The central role of DNA damage and repair in CAG repeat diseases.
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A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration.
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Disrupted striatal neuron inputs and outputs in Huntington's disease.
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The relationship between trinucleotide (CAG) repeat length and clinical features of Huntington's disease.
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6
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.