N Srinivasan, B Bax, T L Blundell, P J Parker. Proteins 1996
Times Cited: 30
Times Cited: 30
Times Cited
Times Co-cited
Similarity
Crystal structure of the cys2 activator-binding domain of protein kinase C delta in complex with phorbol ester.
G Zhang, M G Kazanietz, P M Blumberg, J H Hurley. Cell 1995
G Zhang, M G Kazanietz, P M Blumberg, J H Hurley. Cell 1995
40
Crystal structure of the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase.
D R Knighton, J H Zheng, L F Ten Eyck, V A Ashford, N H Xuong, S S Taylor, J M Sowadski. Science 1991
D R Knighton, J H Zheng, L F Ten Eyck, V A Ashford, N H Xuong, S S Taylor, J M Sowadski. Science 1991
26
Solution structure of a cysteine rich domain of rat protein kinase C.
U Hommel, M Zurini, M Luyten. Nat Struct Biol 1994
U Hommel, M Zurini, M Luyten. Nat Struct Biol 1994
23
Taxonomy and function of C1 protein kinase C homology domains.
J H Hurley, A C Newton, P J Parker, P M Blumberg, Y Nishizuka. Protein Sci 1997
J H Hurley, A C Newton, P J Parker, P M Blumberg, Y Nishizuka. Protein Sci 1997
20
20
Definition of general topological equivalence in protein structures. A procedure involving comparison of properties and relationships through simulated annealing and dynamic programming.
A Sali, T L Blundell. J Mol Biol 1990
A Sali, T L Blundell. J Mol Biol 1990
16
SETOR: hardware-lighted three-dimensional solid model representations of macromolecules.
S V Evans. J Mol Graph 1993
S V Evans. J Mol Graph 1993
16
Non-equivalent roles for the first and second zinc fingers of protein kinase Cdelta. Effect of their mutation on phorbol ester-induced translocation in NIH 3T3 cells.
Z Szallasi, K Bogi, S Gohari, T Biro, P Acs, P M Blumberg. J Biol Chem 1996
Z Szallasi, K Bogi, S Gohari, T Biro, P Acs, P M Blumberg. J Biol Chem 1996
16
The C2 domain calcium-binding motif: structural and functional diversity.
E A Nalefski, J J Falke. Protein Sci 1996
E A Nalefski, J J Falke. Protein Sci 1996
16
Protein kinase C contains a pseudosubstrate prototope in its regulatory domain.
C House, B E Kemp. Science 1987
C House, B E Kemp. Science 1987
16
Bipartite Ca2+-binding motif in C2 domains of synaptotagmin and protein kinase C.
X Shao, B A Davletov, R B Sutton, T C Südhof, J Rizo. Science 1996
X Shao, B A Davletov, R B Sutton, T C Südhof, J Rizo. Science 1996
16
Protein kinase C: structural and spatial regulation by phosphorylation, cofactors, and macromolecular interactions.
A C Newton. Chem Rev 2001
A C Newton. Chem Rev 2001
16
Localization of protein kinases by anchoring proteins: a theme in signal transduction.
D Mochly-Rosen. Science 1995
D Mochly-Rosen. Science 1995
16
Structure of the first C2 domain of synaptotagmin I: a novel Ca2+/phospholipid-binding fold.
R B Sutton, B A Davletov, A M Berghuis, T C Südhof, S R Sprang. Cell 1995
R B Sutton, B A Davletov, A M Berghuis, T C Südhof, S R Sprang. Cell 1995
16
Fragment ranking in modelling of protein structure. Conformationally constrained environmental amino acid substitution tables.
C M Topham, A McLeod, F Eisenmenger, J P Overington, M S Johnson, T L Blundell. J Mol Biol 1993
C M Topham, A McLeod, F Eisenmenger, J P Overington, M S Johnson, T L Blundell. J Mol Biol 1993
13
An evaluation of the performance of an automated procedure for comparative modelling of protein tertiary structure.
N Srinivasan, T L Blundell. Protein Eng 1993
N Srinivasan, T L Blundell. Protein Eng 1993
13
A variable gap penalty function and feature weights for protein 3-D structure comparisons.
Z Y Zhu, A Sali, T L Blundell. Protein Eng 1992
Z Y Zhu, A Sali, T L Blundell. Protein Eng 1992
13
Protein kinases 6. The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification.
S K Hanks, T Hunter. FASEB J 1995
S K Hanks, T Hunter. FASEB J 1995
13
The Protein Data Bank: a computer-based archival file for macromolecular structures.
F C Bernstein, T F Koetzle, G J Williams, E F Meyer, M D Brice, J R Rodgers, O Kennard, T Shimanouchi, M Tasumi. J Mol Biol 1977
F C Bernstein, T F Koetzle, G J Williams, E F Meyer, M D Brice, J R Rodgers, O Kennard, T Shimanouchi, M Tasumi. J Mol Biol 1977
13
Knowledge based modelling of homologous proteins, Part II: Rules for the conformations of substituted sidechains.
M J Sutcliffe, F R Hayes, T L Blundell. Protein Eng 1987
M J Sutcliffe, F R Hayes, T L Blundell. Protein Eng 1987
13
Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons.
A Nicholls, K A Sharp, B Honig. Proteins 1991
A Nicholls, K A Sharp, B Honig. Proteins 1991
13
Protein kinase C and phospholipase C: bilayer interactions and regulation.
J H Hurley, J A Grobler. Curr Opin Struct Biol 1997
J H Hurley, J A Grobler. Curr Opin Struct Biol 1997
13
Identification and characterization of zinc binding sites in protein kinase C.
S R Hubbard, W R Bishop, P Kirschmeier, S J George, S P Cramer, W A Hendrickson. Science 1991
S R Hubbard, W R Bishop, P Kirschmeier, S J George, S P Cramer, W A Hendrickson. Science 1991
13
Requirement for negative charge on "activation loop" of protein kinase C.
J W Orr, A C Newton. J Biol Chem 1994
J W Orr, A C Newton. J Biol Chem 1994
13
Determination of in vivo phosphorylation sites in protein kinase C.
S E Tsutakawa, K F Medzihradszky, A J Flint, A L Burlingame, D E Koshland. J Biol Chem 1995
S E Tsutakawa, K F Medzihradszky, A J Flint, A L Burlingame, D E Koshland. J Biol Chem 1995
13
Phosphorylation at conserved carboxyl-terminal hydrophobic motif regulates the catalytic and regulatory domains of protein kinase C.
A S Edwards, A C Newton. J Biol Chem 1997
A S Edwards, A C Newton. J Biol Chem 1997
13
Activation of protein kinase C by lysophosphatidic acid: dependence on composition of phospholipid vesicles.
J J Sando, O I Chertihin. Biochem J 1996
J J Sando, O I Chertihin. Biochem J 1996
13
Peptides that mimic the pseudosubstrate region of protein kinase C bind to acidic lipids in membranes.
M Mosior, S McLaughlin. Biophys J 1991
M Mosior, S McLaughlin. Biophys J 1991
13
Two-dimensional crystals of protein kinase C.
J M Owens, R H Kretsinger, J J Sando, O I Chertihin. J Struct Biol 1998
J M Owens, R H Kretsinger, J J Sando, O I Chertihin. J Struct Biol 1998
57
Activation mechanisms of conventional protein kinase C isoforms are determined by the ligand affinity and conformational flexibility of their C1 domains.
Bharath Ananthanarayanan, Robert V Stahelin, Michelle A Digman, Wonhwa Cho. J Biol Chem 2003
Bharath Ananthanarayanan, Robert V Stahelin, Michelle A Digman, Wonhwa Cho. J Biol Chem 2003
13
Protein kinase Calpha contains two activator binding sites that bind phorbol esters and diacylglycerols with opposite affinities.
S J Slater, C Ho, M B Kelly, J D Larkin, F J Taddeo, M D Yeager, C D Stubbs. J Biol Chem 1996
S J Slater, C Ho, M B Kelly, J D Larkin, F J Taddeo, M D Yeager, C D Stubbs. J Biol Chem 1996
13
Calcium-independent binding to interfacial phorbol esters causes protein kinase C to associate with membranes in the absence of acidic lipids.
M Mosior, A C Newton. Biochemistry 1996
M Mosior, A C Newton. Biochemistry 1996
13
C2 region-derived peptides inhibit translocation and function of beta protein kinase C in vivo.
D Ron, J Luo, D Mochly-Rosen. J Biol Chem 1995
D Ron, J Luo, D Mochly-Rosen. J Biol Chem 1995
13
Crystal structure of the catalytic subunit of cAMP-dependent protein kinase complexed with MgATP and peptide inhibitor.
J Zheng, D R Knighton, L F ten Eyck, R Karlsson, N Xuong, S S Taylor, J M Sowadski. Biochemistry 1993
J Zheng, D R Knighton, L F ten Eyck, R Karlsson, N Xuong, S S Taylor, J M Sowadski. Biochemistry 1993
10
Tertiary structural constraints on protein evolutionary diversity: templates, key residues and structure prediction.
J Overington, M S Johnson, A Sali, T L Blundell. Proc Biol Sci 1990
J Overington, M S Johnson, A Sali, T L Blundell. Proc Biol Sci 1990
10
Phosphotransferase and substrate binding mechanism of the cAMP-dependent protein kinase catalytic subunit from porcine heart as deduced from the 2.0 A structure of the complex with Mn2+ adenylyl imidodiphosphate and inhibitor peptide PKI(5-24).
D Bossemeyer, R A Engh, V Kinzel, H Ponstingl, R Huber. EMBO J 1993
D Bossemeyer, R A Engh, V Kinzel, H Ponstingl, R Huber. EMBO J 1993
10
Structure of a peptide inhibitor bound to the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase.
D R Knighton, J H Zheng, L F Ten Eyck, N H Xuong, S S Taylor, J M Sowadski. Science 1991
D R Knighton, J H Zheng, L F Ten Eyck, N H Xuong, S S Taylor, J M Sowadski. Science 1991
10
Improved methods for building protein models in electron density maps and the location of errors in these models.
T A Jones, J Y Zou, S W Cowan, M Kjeldgaard. Acta Crystallogr A 1991
T A Jones, J Y Zou, S W Cowan, M Kjeldgaard. Acta Crystallogr A 1991
10
Solution structure of cysteine-rich domain of protein kinase C alpha.
S Ichikawa, H Hatanaka, Y Takeuchi, S Ohno, F Inagaki. J Biochem 1995
S Ichikawa, H Hatanaka, Y Takeuchi, S Ohno, F Inagaki. J Biochem 1995
10
Residues in the second cysteine-rich region of protein kinase C delta relevant to phorbol ester binding as revealed by site-directed mutagenesis.
M G Kazanietz, S Wang, G W Milne, N E Lewin, H L Liu, P M Blumberg. J Biol Chem 1995
M G Kazanietz, S Wang, G W Milne, N E Lewin, H L Liu, P M Blumberg. J Biol Chem 1995
10
NMR structure of a protein kinase C-gamma phorbol-binding domain and study of protein-lipid micelle interactions.
R X Xu, T Pawelczyk, T H Xia, S C Brown. Biochemistry 1997
R X Xu, T Pawelczyk, T H Xia, S C Brown. Biochemistry 1997
10
Protein kinase C is regulated in vivo by three functionally distinct phosphorylations.
L M Keranen, E M Dutil, A C Newton. Curr Biol 1995
L M Keranen, E M Dutil, A C Newton. Curr Biol 1995
10
Threonine-497 is a critical site for permissive activation of protein kinase C alpha.
S Cazaubon, F Bornancin, P J Parker. Biochem J 1994
S Cazaubon, F Bornancin, P J Parker. Biochem J 1994
10
Knowledge-based protein modeling.
M S Johnson, N Srinivasan, R Sowdhamini, T L Blundell. Crit Rev Biochem Mol Biol 1994
M S Johnson, N Srinivasan, R Sowdhamini, T L Blundell. Crit Rev Biochem Mol Biol 1994
10
The protein kinase family: conserved features and deduced phylogeny of the catalytic domains.
S K Hanks, A M Quinn, T Hunter. Science 1988
S K Hanks, A M Quinn, T Hunter. Science 1988
10
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.