C Lazennec, T Meinnel. Anal Biochem 1997
Times Cited: 71
Times Cited: 71
Times Cited
Times Co-cited
Similarity
Genetic characterization of polypeptide deformylase, a distinctive enzyme of eubacterial translation.
D Mazel, S Pochet, P Marlière. EMBO J 1994
D Mazel, S Pochet, P Marlière. EMBO J 1994
66
Control of peptide deformylase activity by metal cations.
S Ragusa, S Blanquet, T Meinnel. J Mol Biol 1998
S Ragusa, S Blanquet, T Meinnel. J Mol Biol 1998
57
Actinonin, a naturally occurring antibacterial agent, is a potent deformylase inhibitor.
D Z Chen, D V Patel, C J Hackbarth, W Wang, G Dreyer, D C Young, P S Margolis, C Wu, Z J Ni, J Trias,[...]. Biochemistry 2000
D Z Chen, D V Patel, C J Hackbarth, W Wang, G Dreyer, D C Young, P S Margolis, C Wu, Z J Ni, J Trias,[...]. Biochemistry 2000
56
Isolation and crystallization of functionally competent Escherichia coli peptide deformylase forms containing either iron or nickel in the active site.
D Groche, A Becker, I Schlichting, W Kabsch, S Schultz, A F Wagner. Biochem Biophys Res Commun 1998
D Groche, A Becker, I Schlichting, W Kabsch, S Schultz, A F Wagner. Biochem Biophys Res Commun 1998
47
Antibiotic activity and characterization of BB-3497, a novel peptide deformylase inhibitor.
J M Clements, R P Beckett, A Brown, G Catlin, M Lobell, S Palan, W Thomas, M Whittaker, S Wood, S Salama,[...]. Antimicrob Agents Chemother 2001
J M Clements, R P Beckett, A Brown, G Catlin, M Lobell, S Palan, W Thomas, M Whittaker, S Wood, S Salama,[...]. Antimicrob Agents Chemother 2001
43
Iron center, substrate recognition and mechanism of peptide deformylase.
A Becker, I Schlichting, W Kabsch, D Groche, S Schultz, A F Wagner. Nat Struct Biol 1998
A Becker, I Schlichting, W Kabsch, D Groche, S Schultz, A F Wagner. Nat Struct Biol 1998
42
A new subclass of the zinc metalloproteases superfamily revealed by the solution structure of peptide deformylase.
T Meinnel, S Blanquet, F Dardel. J Mol Biol 1996
T Meinnel, S Blanquet, F Dardel. J Mol Biol 1996
40
Methionine as translation start signal: a review of the enzymes of the pathway in Escherichia coli.
T Meinnel, Y Mechulam, S Blanquet. Biochimie 1993
T Meinnel, Y Mechulam, S Blanquet. Biochimie 1993
40
Characterization of the Thermus thermophilus locus encoding peptide deformylase and methionyl-tRNA(fMet) formyltransferase.
T Meinnel, S Blanquet. J Bacteriol 1994
T Meinnel, S Blanquet. J Bacteriol 1994
40
Peptide deformylase as a target for new generation, broad spectrum antimicrobial agents.
C Giglione, M Pierre, T Meinnel. Mol Microbiol 2000
C Giglione, M Pierre, T Meinnel. Mol Microbiol 2000
40
Crystal structure of the Escherichia coli peptide deformylase.
M K Chan, W Gong, P T Rajagopalan, B Hao, C M Tsai, D Pei. Biochemistry 1997
M K Chan, W Gong, P T Rajagopalan, B Hao, C M Tsai, D Pei. Biochemistry 1997
39
39
Solution structure of nickel-peptide deformylase.
F Dardel, S Ragusa, C Lazennec, S Blanquet, T Meinnel. J Mol Biol 1998
F Dardel, S Ragusa, C Lazennec, S Blanquet, T Meinnel. J Mol Biol 1998
38
Purification, characterization, and inhibition of peptide deformylase from Escherichia coli.
P T Rajagopalan, A Datta, D Pei. Biochemistry 1997
P T Rajagopalan, A Datta, D Pei. Biochemistry 1997
38
Mapping of the active site zinc ligands of peptide deformylase.
T Meinnel, C Lazennec, S Blanquet. J Mol Biol 1995
T Meinnel, C Lazennec, S Blanquet. J Mol Biol 1995
39
Characterization of cobalt(II)-substituted peptide deformylase: function of the metal ion and the catalytic residue Glu-133.
P T Rajagopalan, S Grimme, D Pei. Biochemistry 2000
P T Rajagopalan, S Grimme, D Pei. Biochemistry 2000
36
Identification of eukaryotic peptide deformylases reveals universality of N-terminal protein processing mechanisms.
C Giglione, A Serero, M Pierre, B Boisson, T Meinnel. EMBO J 2000
C Giglione, A Serero, M Pierre, B Boisson, T Meinnel. EMBO J 2000
36
The crystal structures of four peptide deformylases bound to the antibiotic actinonin reveal two distinct types: a platform for the structure-based design of antibacterial agents.
Jean-Pierre Guilloteau, Magali Mathieu, Carmela Giglione, Véronique Blanc, Alain Dupuy, Miline Chevrier, Patricia Gil, Alain Famechon, Thierry Meinnel, Vincent Mikol. J Mol Biol 2002
Jean-Pierre Guilloteau, Magali Mathieu, Carmela Giglione, Véronique Blanc, Alain Dupuy, Miline Chevrier, Patricia Gil, Alain Famechon, Thierry Meinnel, Vincent Mikol. J Mol Biol 2002
36
Structure-function relationships within the peptide deformylase family. Evidence for a conserved architecture of the active site involving three conserved motifs and a metal ion.
T Meinnel, C Lazennec, S Villoing, S Blanquet. J Mol Biol 1997
T Meinnel, C Lazennec, S Villoing, S Blanquet. J Mol Biol 1997
35
Structure of peptide deformylase and identification of the substrate binding site.
A Becker, I Schlichting, W Kabsch, S Schultz, A F Wagner. J Biol Chem 1998
A Becker, I Schlichting, W Kabsch, S Schultz, A F Wagner. J Biol Chem 1998
33
Structural basis for the design of antibiotics targeting peptide deformylase.
B Hao, W Gong, P T Rajagopalan, Y Zhou, D Pei, M K Chan. Biochemistry 1999
B Hao, W Gong, P T Rajagopalan, Y Zhou, D Pei, M K Chan. Biochemistry 1999
31
Peptide deformylase in Staphylococcus aureus: resistance to inhibition is mediated by mutations in the formyltransferase gene.
P S Margolis, C J Hackbarth, D C Young, W Wang, D Chen, Z Yuan, R White, J Trias. Antimicrob Agents Chemother 2000
P S Margolis, C J Hackbarth, D C Young, W Wang, D Chen, Z Yuan, R White, J Trias. Antimicrob Agents Chemother 2000
30
Enzymatic properties of Escherichia coli peptide deformylase.
T Meinnel, S Blanquet. J Bacteriol 1995
T Meinnel, S Blanquet. J Bacteriol 1995
28
Design and synthesis of substrate analogue inhibitors of peptide deformylase.
T Meinnel, L Patiny, S Ragusa, S Blanquet. Biochemistry 1999
T Meinnel, L Patiny, S Ragusa, S Blanquet. Biochemistry 1999
31
Hydroxamic acid derivatives as potent peptide deformylase inhibitors and antibacterial agents.
C Apfel, D W Banner, D Bur, M Dietz, T Hirata, C Hubschwerlen, H Locher, M G Page, W Pirson, G Rossé,[...]. J Med Chem 2000
C Apfel, D W Banner, D Bur, M Dietz, T Hirata, C Hubschwerlen, H Locher, M G Page, W Pirson, G Rossé,[...]. J Med Chem 2000
28
Characterization of a human peptide deformylase: implications for antibacterial drug design.
Kiet T Nguyen, Xubo Hu, Craig Colton, Ratna Chakrabarti, Michael X Zhu, Dehua Pei. Biochemistry 2003
Kiet T Nguyen, Xubo Hu, Craig Colton, Ratna Chakrabarti, Michael X Zhu, Dehua Pei. Biochemistry 2003
26
50
Substrate recognition and selectivity of peptide deformylase. Similarities and differences with metzincins and thermolysin.
S Ragusa, P Mouchet, C Lazennec, V Dive, T Meinnel. J Mol Biol 1999
S Ragusa, P Mouchet, C Lazennec, V Dive, T Meinnel. J Mol Biol 1999
32
Synthesis and antibacterial activity of peptide deformylase inhibitors.
K M Huntington, T Yi, Y Wei, D Pei. Biochemistry 2000
K M Huntington, T Yi, Y Wei, D Pei. Biochemistry 2000
27
23
An unusual peptide deformylase features in the human mitochondrial N-terminal methionine excision pathway.
Alexandre Serero, Carmela Giglione, Alessandro Sardini, Juan Martinez-Sanz, Thierry Meinnel. J Biol Chem 2003
Alexandre Serero, Carmela Giglione, Alessandro Sardini, Juan Martinez-Sanz, Thierry Meinnel. J Biol Chem 2003
23
Evidence that peptide deformylase and methionyl-tRNA(fMet) formyltransferase are encoded within the same operon in Escherichia coli.
T Meinnel, S Blanquet. J Bacteriol 1993
T Meinnel, S Blanquet. J Bacteriol 1993
25
Peptide deformylase of eukaryotic protists: a target for new antiparasitic agents?
T Meinnel. Parasitol Today 2000
T Meinnel. Parasitol Today 2000
27
The C-terminal domain of peptide deformylase is disordered and dispensable for activity.
T Meinnel, C Lazennec, F Dardel, J M Schmitter, S Blanquet. FEBS Lett 1996
T Meinnel, C Lazennec, F Dardel, J M Schmitter, S Blanquet. FEBS Lett 1996
32
Characterization of an eukaryotic peptide deformylase from Plasmodium falciparum.
V Bracchi-Ricard, K T Nguyen, Y Zhou, P T Rajagopalan, D Chakrabarti, D Pei. Arch Biochem Biophys 2001
V Bracchi-Ricard, K T Nguyen, Y Zhou, P T Rajagopalan, D Chakrabarti, D Pei. Arch Biochem Biophys 2001
26
A new human peptide deformylase inhibitable by actinonin.
Mona D Lee, Christophe Antczak, Yueming Li, Francis M Sirotnak, William G Bornmann, David A Scheinberg. Biochem Biophys Res Commun 2003
Mona D Lee, Christophe Antczak, Yueming Li, Francis M Sirotnak, William G Bornmann, David A Scheinberg. Biochem Biophys Res Commun 2003
27
Determination of substrate specificity for peptide deformylase through the screening of a combinatorial peptide library.
Y J Hu, Y Wei, Y Zhou, P T Rajagopalan, D Pei. Biochemistry 1999
Y J Hu, Y Wei, Y Zhou, P T Rajagopalan, D Pei. Biochemistry 1999
19
A survey of polypeptide deformylase function throughout the eubacterial lineage.
D Mazel, E Coïc, S Blanchard, W Saurin, P Marlière. J Mol Biol 1997
D Mazel, E Coïc, S Blanchard, W Saurin, P Marlière. J Mol Biol 1997
22
Processing of the N termini of nascent polypeptide chains requires deformylation prior to methionine removal.
J Solbiati, A Chapman-Smith, J L Miller, C G Miller, J E Cronan. J Mol Biol 1999
J Solbiati, A Chapman-Smith, J L Miller, C G Miller, J E Cronan. J Mol Biol 1999
15
N-formylmethionyl-sRNA as the initiator of protein synthesis.
J M Adams, M R Capecchi. Proc Natl Acad Sci U S A 1966
J M Adams, M R Capecchi. Proc Natl Acad Sci U S A 1966
15
Crystallography & NMR system: A new software suite for macromolecular structure determination.
A T Brünger, P D Adams, G M Clore, W L DeLano, P Gros, R W Grosse-Kunstleve, J S Jiang, J Kuszewski, M Nilges, N S Pannu,[...]. Acta Crystallogr D Biol Crystallogr 1998
A T Brünger, P D Adams, G M Clore, W L DeLano, P Gros, R W Grosse-Kunstleve, J S Jiang, J Kuszewski, M Nilges, N S Pannu,[...]. Acta Crystallogr D Biol Crystallogr 1998
15
Methionine aminopeptidase gene of Escherichia coli is essential for cell growth.
S Y Chang, E C McGary, S Chang. J Bacteriol 1989
S Y Chang, E C McGary, S Chang. J Bacteriol 1989
14
Peptide aldehyde inhibitors of bacterial peptide deformylases.
D J Durand, B Gordon Green, J F O'Connell, S K Grant. Arch Biochem Biophys 1999
D J Durand, B Gordon Green, J F O'Connell, S K Grant. Arch Biochem Biophys 1999
33
Crystals of peptide deformylase from Plasmodium falciparum reveal critical characteristics of the active site for drug design.
Abhinav Kumar, Kiet T Nguyen, Sumant Srivathsan, Brad Ornstein, Stewart Turley, Irwin Hirsh, Dehua Pei, Wim G J Hol. Structure 2002
Abhinav Kumar, Kiet T Nguyen, Sumant Srivathsan, Brad Ornstein, Stewart Turley, Irwin Hirsh, Dehua Pei, Wim G J Hol. Structure 2002
25
Distinctive features of the two classes of eukaryotic peptide deformylases.
A Serero, C Giglione, T Meinnel. J Mol Biol 2001
A Serero, C Giglione, T Meinnel. J Mol Biol 2001
15
Resistance of Streptococcus pneumoniae to deformylase inhibitors is due to mutations in defB.
P Margolis, C Hackbarth, S Lopez, M Maniar, W Wang, Z Yuan, R White, J Trias. Antimicrob Agents Chemother 2001
P Margolis, C Hackbarth, S Lopez, M Maniar, W Wang, Z Yuan, R White, J Trias. Antimicrob Agents Chemother 2001
17
Protein chain initiation and deformylation in B. subtilis homogenates.
M Takeda, R E Webster. Proc Natl Acad Sci U S A 1968
M Takeda, R E Webster. Proc Natl Acad Sci U S A 1968
12
Actinonin: an antibiotic substance produced by an actinomycete.
J J GORDON, B K KELLY, G A MILLER. Nature 1962
J J GORDON, B K KELLY, G A MILLER. Nature 1962
13
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.