S Kyo, M Takakura, T Kohama, M Inoue. Cancer Res 1997
Times Cited: 216
Times Cited: 216
Times Cited
Times Co-cited
Similarity
Specific association of human telomerase activity with immortal cells and cancer.
N W Kim, M A Piatyszek, K R Prowse, C B Harley, M D West, P L Ho, G M Coviello, W E Wright, S L Weinrich, J W Shay. Science 1994
N W Kim, M A Piatyszek, K R Prowse, C B Harley, M D West, P L Ho, G M Coviello, W E Wright, S L Weinrich, J W Shay. Science 1994
58
Extension of life-span by introduction of telomerase into normal human cells.
A G Bodnar, M Ouellette, M Frolkis, S E Holt, C P Chiu, G B Morin, C B Harley, J W Shay, S Lichtsteiner, W E Wright. Science 1998
A G Bodnar, M Ouellette, M Frolkis, S E Holt, C P Chiu, G B Morin, C B Harley, J W Shay, S Lichtsteiner, W E Wright. Science 1998
30
Telomerase catalytic subunit homologs from fission yeast and human.
T M Nakamura, G B Morin, K B Chapman, S L Weinrich, W H Andrews, J Lingner, C B Harley, T R Cech. Science 1997
T M Nakamura, G B Morin, K B Chapman, S L Weinrich, W H Andrews, J Lingner, C B Harley, T R Cech. Science 1997
27
Telomeres shorten during ageing of human fibroblasts.
C B Harley, A B Futcher, C W Greider. Nature 1990
C B Harley, A B Futcher, C W Greider. Nature 1990
27
Activation of telomerase in human lymphocytes and hematopoietic progenitor cells.
K Hiyama, Y Hirai, S Kyoizumi, M Akiyama, E Hiyama, M A Piatyszek, J W Shay, S Ishioka, M Yamakido. J Immunol 1995
K Hiyama, Y Hirai, S Kyoizumi, M Akiyama, E Hiyama, M A Piatyszek, J W Shay, S Ishioka, M Yamakido. J Immunol 1995
26
Estrogen activates telomerase.
S Kyo, M Takakura, T Kanaya, W Zhuo, K Fujimoto, Y Nishio, A Orimo, M Inoue. Cancer Res 1999
S Kyo, M Takakura, T Kanaya, W Zhuo, K Fujimoto, Y Nishio, A Orimo, M Inoue. Cancer Res 1999
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The RNA component of human telomerase.
J Feng, W D Funk, S S Wang, S L Weinrich, A A Avilion, C P Chiu, R R Adams, E Chang, R C Allsopp, J Yu. Science 1995
J Feng, W D Funk, S S Wang, S L Weinrich, A A Avilion, C P Chiu, R R Adams, E Chang, R C Allsopp, J Yu. Science 1995
23
Telomerase activity in human germline and embryonic tissues and cells.
W E Wright, M A Piatyszek, W E Rainey, W Byrd, J W Shay. Dev Genet 1996
W E Wright, M A Piatyszek, W E Rainey, W Byrd, J W Shay. Dev Genet 1996
22
Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT.
S L Weinrich, R Pruzan, L Ma, M Ouellette, V M Tesmer, S E Holt, A G Bodnar, S Lichtsteiner, N W Kim, J B Trager,[...]. Nat Genet 1997
S L Weinrich, R Pruzan, L Ma, M Ouellette, V M Tesmer, S E Holt, A G Bodnar, S Lichtsteiner, N W Kim, J B Trager,[...]. Nat Genet 1997
21
hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization.
M Meyerson, C M Counter, E N Eaton, L W Ellisen, P Steiner, S D Caddle, L Ziaugra, R L Beijersbergen, M J Davidoff, Q Liu,[...]. Cell 1997
M Meyerson, C M Counter, E N Eaton, L W Ellisen, P Steiner, S D Caddle, L Ziaugra, R L Beijersbergen, M J Davidoff, Q Liu,[...]. Cell 1997
21
Expression of telomerase activity in human endometrium is localized to epithelial glandular cells and regulated in a menstrual phase-dependent manner correlated with cell proliferation.
M Tanaka, S Kyo, M Takakura, T Kanaya, T Sagawa, K Yamashita, Y Okada, E Hiyama, M Inoue. Am J Pathol 1998
M Tanaka, S Kyo, M Takakura, T Kanaya, T Sagawa, K Yamashita, Y Okada, E Hiyama, M Inoue. Am J Pathol 1998
28
Telomerase activity in the regenerative basal layer of the epidermis inhuman skin and in immortal and carcinoma-derived skin keratinocytes.
C Härle-Bachor, P Boukamp. Proc Natl Acad Sci U S A 1996
C Härle-Bachor, P Boukamp. Proc Natl Acad Sci U S A 1996
21
Induction of hTERT expression and telomerase activity by estrogens in human ovary epithelium cells.
S Misiti, S Nanni, G Fontemaggi, Y S Cong, J Wen, H W Hirte, G Piaggio, A Sacchi, A Pontecorvi, S Bacchetti,[...]. Mol Cell Biol 2000
S Misiti, S Nanni, G Fontemaggi, Y S Cong, J Wen, H W Hirte, G Piaggio, A Sacchi, A Pontecorvi, S Bacchetti,[...]. Mol Cell Biol 2000
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19
Telomerase activity in normal and malignant hematopoietic cells.
D Broccoli, J W Young, T de Lange. Proc Natl Acad Sci U S A 1995
D Broccoli, J W Young, T de Lange. Proc Natl Acad Sci U S A 1995
19
Cloning of human telomerase catalytic subunit (hTERT) gene promoter and identification of proximal core promoter sequences essential for transcriptional activation in immortalized and cancer cells.
M Takakura, S Kyo, T Kanaya, H Hirano, J Takeda, M Yutsudo, M Inoue. Cancer Res 1999
M Takakura, S Kyo, T Kanaya, H Hirano, J Takeda, M Yutsudo, M Inoue. Cancer Res 1999
18
Telomerase activity in normal leukocytes and in hematologic malignancies.
C M Counter, J Gupta, C B Harley, B Leber, S Bacchetti. Blood 1995
C M Counter, J Gupta, C B Harley, B Leber, S Bacchetti. Blood 1995
18
Mammalian telomeres end in a large duplex loop.
J D Griffith, L Comeau, S Rosenfield, R M Stansel, A Bianchi, H Moss, T de Lange. Cell 1999
J D Griffith, L Comeau, S Rosenfield, R M Stansel, A Bianchi, H Moss, T de Lange. Cell 1999
16
Telomerase activity concentrates in the mitotically active segments of human hair follicles.
R D Ramirez, W E Wright, J W Shay, R S Taylor. J Invest Dermatol 1997
R D Ramirez, W E Wright, J W Shay, R S Taylor. J Invest Dermatol 1997
16
Proliferation-associated regulation of telomerase activity in human endometrium and its potential implication in early cancer diagnosis.
T Saito, A Schneider, N Martel, H Mizumoto, M Bulgay-Moerschel, R Kudo, H Nakazawa. Biochem Biophys Res Commun 1997
T Saito, A Schneider, N Martel, H Mizumoto, M Bulgay-Moerschel, R Kudo, H Nakazawa. Biochem Biophys Res Commun 1997
21
A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon.
A M Olovnikov. J Theor Biol 1973
A M Olovnikov. J Theor Biol 1973
15
Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity.
C M Counter, A A Avilion, C E LeFeuvre, N G Stewart, C W Greider, C B Harley, S Bacchetti. EMBO J 1992
C M Counter, A A Avilion, C E LeFeuvre, N G Stewart, C W Greider, C B Harley, S Bacchetti. EMBO J 1992
15
Telomerase activity in normal human epithelial cells.
S Yasumoto, C Kunimura, K Kikuchi, H Tahara, H Ohji, H Yamamoto, T Ide, T Utakoji. Oncogene 1996
S Yasumoto, C Kunimura, K Kikuchi, H Tahara, H Ohji, H Yamamoto, T Ide, T Utakoji. Oncogene 1996
15
Telomerase activity in benign endometrium and endometrial carcinoma.
T P Brien, B V Kallakury, C V Lowry, R A Ambros, P J Muraca, J H Malfetano, J S Ross. Cancer Res 1997
T P Brien, B V Kallakury, C V Lowry, R A Ambros, P J Muraca, J H Malfetano, J S Ross. Cancer Res 1997
21
A prospective, randomized study of endometrial telomerase during the menstrual cycle.
C D Williams, J F Boggess, L R LaMarque, W R Meyer, M J Murray, M A Fritz, B A Lessey. J Clin Endocrinol Metab 2001
C D Williams, J F Boggess, L R LaMarque, W R Meyer, M J Murray, M A Fritz, B A Lessey. J Clin Endocrinol Metab 2001
35
Human telomerase and its regulation.
Yu-Sheng Cong, Woodring E Wright, Jerry W Shay. Microbiol Mol Biol Rev 2002
Yu-Sheng Cong, Woodring E Wright, Jerry W Shay. Microbiol Mol Biol Rev 2002
14
Human telomerase reverse transcriptase as a critical determinant of telomerase activity in normal and malignant endometrial tissues.
S Kyo, T Kanaya, M Takakura, M Tanaka, M Inoue. Int J Cancer 1999
S Kyo, T Kanaya, M Takakura, M Tanaka, M Inoue. Int J Cancer 1999
13
Telomere length predicts replicative capacity of human fibroblasts.
R C Allsopp, H Vaziri, C Patterson, S Goldstein, E V Younglai, A B Futcher, C W Greider, C B Harley. Proc Natl Acad Sci U S A 1992
R C Allsopp, H Vaziri, C Patterson, S Goldstein, E V Younglai, A B Futcher, C W Greider, C B Harley. Proc Natl Acad Sci U S A 1992
13
Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas.
J Nakayama, H Tahara, E Tahara, M Saito, K Ito, H Nakamura, T Nakanishi, E Tahara, T Ide, F Ishikawa. Nat Genet 1998
J Nakayama, H Tahara, E Tahara, M Saito, K Ito, H Nakamura, T Nakanishi, E Tahara, T Ide, F Ishikawa. Nat Genet 1998
12
Isolation of a candidate human telomerase catalytic subunit gene, which reveals complex splicing patterns in different cell types.
A Kilian, D D Bowtell, H E Abud, G R Hime, D J Venter, P K Keese, E L Duncan, R R Reddel, R A Jefferson. Hum Mol Genet 1997
A Kilian, D D Bowtell, H E Abud, G R Hime, D J Venter, P K Keese, E L Duncan, R R Reddel, R A Jefferson. Hum Mol Genet 1997
12
Identification of a specific telomere terminal transferase activity in Tetrahymena extracts.
C W Greider, E H Blackburn. Cell 1985
C W Greider, E H Blackburn. Cell 1985
12
Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.
T Kiyono, S A Foster, J I Koop, J K McDougall, D A Galloway, A J Klingelhutz. Nature 1998
T Kiyono, S A Foster, J I Koop, J K McDougall, D A Galloway, A J Klingelhutz. Nature 1998
12
Telomerase maintains telomere structure in normal human cells.
Kenkichi Masutomi, Evan Y Yu, Shilagardy Khurts, Ittai Ben-Porath, Jennifer L Currier, Geoffrey B Metz, Mary W Brooks, Shuichi Kaneko, Seishi Murakami, James A DeCaprio,[...]. Cell 2003
Kenkichi Masutomi, Evan Y Yu, Shilagardy Khurts, Ittai Ben-Porath, Jennifer L Currier, Geoffrey B Metz, Mary W Brooks, Shuichi Kaneko, Seishi Murakami, James A DeCaprio,[...]. Cell 2003
12
A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis.
C W Greider, E H Blackburn. Nature 1989
C W Greider, E H Blackburn. Nature 1989
11
Direct activation of TERT transcription by c-MYC.
K J Wu, C Grandori, M Amacker, N Simon-Vermot, A Polack, J Lingner, R Dalla-Favera. Nat Genet 1999
K J Wu, C Grandori, M Amacker, N Simon-Vermot, A Polack, J Lingner, R Dalla-Favera. Nat Genet 1999
11
Progesterone regulates human telomerase reverse transcriptase gene expression via activation of mitogen-activated protein kinase signaling pathway.
Z Wang, S Kyo, M Takakura, M Tanaka, N Yatabe, Y Maida, M Fujiwara, J Hayakawa, M Ohmichi, K Koike,[...]. Cancer Res 2000
Z Wang, S Kyo, M Takakura, M Tanaka, N Yatabe, Y Maida, M Fujiwara, J Hayakawa, M Ohmichi, K Koike,[...]. Cancer Res 2000
11
Expression of human telomerase subunits and correlation with telomerase activity in cervical cancer.
M Takakura, S Kyo, T Kanaya, M Tanaka, M Inoue. Cancer Res 1998
M Takakura, S Kyo, T Kanaya, M Tanaka, M Inoue. Cancer Res 1998
11
Telomerase activity in gynecological tumors.
S Kyo, T Kanaya, H Ishikawa, H Ueno, M Inoue. Clin Cancer Res 1996
S Kyo, T Kanaya, H Ishikawa, H Ueno, M Inoue. Clin Cancer Res 1996
12
Shelterin: the protein complex that shapes and safeguards human telomeres.
Titia de Lange. Genes Dev 2005
Titia de Lange. Genes Dev 2005
11
The human telomerase catalytic subunit hTERT: organization of the gene and characterization of the promoter.
Y S Cong, J Wen, S Bacchetti. Hum Mol Genet 1999
Y S Cong, J Wen, S Bacchetti. Hum Mol Genet 1999
10
Sp1 cooperates with c-Myc to activate transcription of the human telomerase reverse transcriptase gene (hTERT).
S Kyo, M Takakura, T Taira, T Kanaya, H Itoh, M Yutsudo, H Ariga, M Inoue. Nucleic Acids Res 2000
S Kyo, M Takakura, T Taira, T Kanaya, H Itoh, M Yutsudo, H Ariga, M Inoue. Nucleic Acids Res 2000
10
A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes.
R K Moyzis, J M Buckingham, L S Cram, M Dani, L L Deaven, M D Jones, J Meyne, R L Ratliff, J R Wu. Proc Natl Acad Sci U S A 1988
R K Moyzis, J M Buckingham, L S Cram, M Dani, L L Deaven, M D Jones, J Meyne, R L Ratliff, J R Wu. Proc Natl Acad Sci U S A 1988
10
Induction of hTERT expression and phosphorylation by estrogen via Akt cascade in human ovarian cancer cell lines.
Akiko Kimura, Masahide Ohmichi, Jun Kawagoe, Satoru Kyo, Seiji Mabuchi, Toshifumi Takahashi, Chika Ohshima, Emi Arimoto-Ishida, Yukihiro Nishio, Masaki Inoue,[...]. Oncogene 2004
Akiko Kimura, Masahide Ohmichi, Jun Kawagoe, Satoru Kyo, Seiji Mabuchi, Toshifumi Takahashi, Chika Ohshima, Emi Arimoto-Ishida, Yukihiro Nishio, Masaki Inoue,[...]. Oncogene 2004
10
Telomerase activity in human development is regulated by human telomerase reverse transcriptase (hTERT) transcription and by alternate splicing of hTERT transcripts.
G A Ulaner, J F Hu, T H Vu, L C Giudice, A R Hoffman. Cancer Res 1998
G A Ulaner, J F Hu, T H Vu, L C Giudice, A R Hoffman. Cancer Res 1998
9
TRF2 protects human telomeres from end-to-end fusions.
B van Steensel, A Smogorzewska, T de Lange. Cell 1998
B van Steensel, A Smogorzewska, T de Lange. Cell 1998
9
Cloning and characterization of the promoter region of human telomerase reverse transcriptase gene.
I Horikawa, P L Cable, C Afshari, J C Barrett. Cancer Res 1999
I Horikawa, P L Cable, C Afshari, J C Barrett. Cancer Res 1999
9
Control of telomere length by the human telomeric protein TRF1.
B van Steensel, T de Lange. Nature 1997
B van Steensel, T de Lange. Nature 1997
9
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.