A citation-based method for searching scientific literature

M Serrano, A W Lin, M E McCurrach, D Beach, S W Lowe. Cell 1997
Times Cited: 3190







List of co-cited articles
998 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor.
Jean-Philippe Coppé, Christopher K Patil, Francis Rodier, Yu Sun, Denise P Muñoz, Joshua Goldstein, Peter S Nelson, Pierre-Yves Desprez, Judith Campisi. PLoS Biol 2008
33

The senescence-associated secretory phenotype: the dark side of tumor suppression.
Jean-Philippe Coppé, Pierre-Yves Desprez, Ana Krtolica, Judith Campisi. Annu Rev Pathol 2010
31

The serial cultivation of human diploid cell strains.
L HAYFLICK, P S MOORHEAD. Exp Cell Res 1961
29

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders.
Darren J Baker, Tobias Wijshake, Tamar Tchkonia, Nathan K LeBrasseur, Bennett G Childs, Bart van de Sluis, James L Kirkland, Jan M van Deursen. Nature 2011
28

Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan.
Darren J Baker, Bennett G Childs, Matej Durik, Melinde E Wijers, Cynthia J Sieben, Jian Zhong, Rachel A Saltness, Karthik B Jeganathan, Grace Casaclang Verzosa, Abdulmohammad Pezeshki,[...]. Nature 2016
28

An essential role for senescent cells in optimal wound healing through secretion of PDGF-AA.
Marco Demaria, Naoko Ohtani, Sameh A Youssef, Francis Rodier, Wendy Toussaint, James R Mitchell, Remi-Martin Laberge, Jan Vijg, Harry Van Steeg, Martijn E T Dollé,[...]. Dev Cell 2014
647
26

Cellular Senescence: Defining a Path Forward.
Vassilis Gorgoulis, Peter D Adams, Andrea Alimonti, Dorothy C Bennett, Oliver Bischof, Cleo Bishop, Judith Campisi, Manuel Collado, Konstantinos Evangelou, Gerardo Ferbeyre,[...]. Cell 2019
278
24

A biomarker that identifies senescent human cells in culture and in aging skin in vivo.
G P Dimri, X Lee, G Basile, M Acosta, G Scott, C Roskelley, E E Medrano, M Linskens, I Rubelj, O Pereira-Smith. Proc Natl Acad Sci U S A 1995
24

Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence.
Masashi Narita, Sabrina Nũnez, Edith Heard, Masako Narita, Athena W Lin, Stephen A Hearn, David L Spector, Gregory J Hannon, Scott W Lowe. Cell 2003
23

Programmed cell senescence during mammalian embryonic development.
Daniel Muñoz-Espín, Marta Cañamero, Antonio Maraver, Gonzalo Gómez-López, Julio Contreras, Silvia Murillo-Cuesta, Alfonso Rodríguez-Baeza, Isabel Varela-Nieto, Jesús Ruberte, Manuel Collado,[...]. Cell 2013
590
23

Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network.
Thomas Kuilman, Chrysiis Michaloglou, Liesbeth C W Vredeveld, Sirith Douma, Remco van Doorn, Christophe J Desmet, Lucien A Aarden, Wolter J Mooi, Daniel S Peeper. Cell 2008
21

A complex secretory program orchestrated by the inflammasome controls paracrine senescence.
Juan Carlos Acosta, Ana Banito, Torsten Wuestefeld, Athena Georgilis, Peggy Janich, Jennifer P Morton, Dimitris Athineos, Tae-Won Kang, Felix Lasitschka, Mindaugas Andrulis,[...]. Nat Cell Biol 2013
755
21

Chemokine signaling via the CXCR2 receptor reinforces senescence.
Juan C Acosta, Ana O'Loghlen, Ana Banito, Maria V Guijarro, Arnaud Augert, Selina Raguz, Marzia Fumagalli, Marco Da Costa, Celia Brown, Nikolay Popov,[...]. Cell 2008
926
20


Senescence is a developmental mechanism that contributes to embryonic growth and patterning.
Mekayla Storer, Alba Mas, Alexandre Robert-Moreno, Matteo Pecoraro, M Carmen Ortells, Valeria Di Giacomo, Reut Yosef, Noam Pilpel, Valery Krizhanovsky, James Sharpe,[...]. Cell 2013
489
20

Hallmarks of Cellular Senescence.
Alejandra Hernandez-Segura, Jamil Nehme, Marco Demaria. Trends Cell Biol 2018
362
19

The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.
Yi Zhu, Tamara Tchkonia, Tamar Pirtskhalava, Adam C Gower, Husheng Ding, Nino Giorgadze, Allyson K Palmer, Yuji Ikeno, Gene B Hubbard, Marc Lenburg,[...]. Aging Cell 2015
649
18

Tumour biology: senescence in premalignant tumours.
Manuel Collado, Jesús Gil, Alejo Efeyan, Carmen Guerra, Alberto J Schuhmacher, Marta Barradas, Alberto Benguría, Angel Zaballos, Juana M Flores, Mariano Barbacid,[...]. Nature 2005
943
17

Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication.
Raffaella Di Micco, Marzia Fumagalli, Angelo Cicalese, Sara Piccinin, Patrizia Gasparini, Chiara Luise, Catherine Schurra, Massimiliano Garre', Paolo Giovanni Nuciforo, Aaron Bensimon,[...]. Nature 2006
17

Cellular senescence: from physiology to pathology.
Daniel Muñoz-Espín, Manuel Serrano. Nat Rev Mol Cell Biol 2014
972
17

Cellular senescence: when bad things happen to good cells.
Judith Campisi, Fabrizio d'Adda di Fagagna. Nat Rev Mol Cell Biol 2007
17

Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice.
Jianhui Chang, Yingying Wang, Lijian Shao, Remi-Martin Laberge, Marco Demaria, Judith Campisi, Krishnamurthy Janakiraman, Norman E Sharpless, Sheng Ding, Wei Feng,[...]. Nat Med 2016
620
17

Cellular Senescence Promotes Adverse Effects of Chemotherapy and Cancer Relapse.
Marco Demaria, Monique N O'Leary, Jianhui Chang, Lijian Shao, Su Liu, Fatouma Alimirah, Kristin Koenig, Catherine Le, Natalia Mitin, Allison M Deal,[...]. Cancer Discov 2017
351
17

BRAFE600-associated senescence-like cell cycle arrest of human naevi.
Chrysiis Michaloglou, Liesbeth C W Vredeveld, Maria S Soengas, Christophe Denoyelle, Thomas Kuilman, Chantal M A M van der Horst, Donné M Majoor, Jerry W Shay, Wolter J Mooi, Daniel S Peeper. Nature 2005
17

The essence of senescence.
Thomas Kuilman, Chrysiis Michaloglou, Wolter J Mooi, Daniel S Peeper. Genes Dev 2010
16

Forging a signature of in vivo senescence.
Norman E Sharpless, Charles J Sherr. Nat Rev Cancer 2015
371
16

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion.
Francis Rodier, Jean-Philippe Coppé, Christopher K Patil, Wieteke A M Hoeijmakers, Denise P Muñoz, Saba R Raza, Adam Freund, Eric Campeau, Albert R Davalos, Judith Campisi. Nat Cell Biol 2009
16

Lamin B1 loss is a senescence-associated biomarker.
Adam Freund, Remi-Martin Laberge, Marco Demaria, Judith Campisi. Mol Biol Cell 2012
353
15

The DNA damage response induces inflammation and senescence by inhibiting autophagy of GATA4.
Chanhee Kang, Qikai Xu, Timothy D Martin, Mamie Z Li, Marco Demaria, Liviu Aron, Tao Lu, Bruce A Yankner, Judith Campisi, Stephen J Elledge. Science 2015
356
15

Aging, cellular senescence, and cancer.
Judith Campisi. Annu Rev Physiol 2013
15

MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation.
Remi-Martin Laberge, Yu Sun, Arturo V Orjalo, Christopher K Patil, Adam Freund, Lili Zhou, Samuel C Curran, Albert R Davalos, Kathleen A Wilson-Edell, Su Liu,[...]. Nat Cell Biol 2015
433
15

Senescence surveillance of pre-malignant hepatocytes limits liver cancer development.
Tae-Won Kang, Tetyana Yevsa, Norman Woller, Lisa Hoenicke, Torsten Wuestefeld, Daniel Dauch, Anja Hohmeyer, Marcus Gereke, Ramona Rudalska, Anna Potapova,[...]. Nature 2011
705
15

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis.
Zhenbang Chen, Lloyd C Trotman, David Shaffer, Hui-Kuan Lin, Zohar A Dotan, Masaru Niki, Jason A Koutcher, Howard I Scher, Thomas Ludwig, William Gerald,[...]. Nature 2005
14

A DNA damage checkpoint response in telomere-initiated senescence.
Fabrizio d'Adda di Fagagna, Philip M Reaper, Lorena Clay-Farrace, Heike Fiegler, Philippa Carr, Thomas Von Zglinicki, Gabriele Saretzki, Nigel P Carter, Stephen P Jackson. Nature 2003
14

Senescence of activated stellate cells limits liver fibrosis.
Valery Krizhanovsky, Monica Yon, Ross A Dickins, Stephen Hearn, Janelle Simon, Cornelius Miething, Herman Yee, Lars Zender, Scott W Lowe. Cell 2008
981
14


Unmasking Transcriptional Heterogeneity in Senescent Cells.
Alejandra Hernandez-Segura, Tristan V de Jong, Simon Melov, Victor Guryev, Judith Campisi, Marco Demaria. Curr Biol 2017
167
14

Identification of a novel senolytic agent, navitoclax, targeting the Bcl-2 family of anti-apoptotic factors.
Yi Zhu, Tamara Tchkonia, Heike Fuhrmann-Stroissnigg, Haiming M Dai, Yuanyuan Y Ling, Michael B Stout, Tamar Pirtskhalava, Nino Giorgadze, Kurt O Johnson, Cory B Giles,[...]. Aging Cell 2016
295
14

Oncogene-induced senescence as an initial barrier in lymphoma development.
Melanie Braig, Soyoung Lee, Christoph Loddenkemper, Cornelia Rudolph, Antoine H F M Peters, Brigitte Schlegelberger, Harald Stein, Bernd Dörken, Thomas Jenuwein, Clemens A Schmitt. Nature 2005
783
13

mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype.
Nicolás Herranz, Suchira Gallage, Massimiliano Mellone, Torsten Wuestefeld, Sabrina Klotz, Christopher J Hanley, Selina Raguz, Juan Carlos Acosta, Andrew J Innes, Ana Banito,[...]. Nat Cell Biol 2015
270
13

Senescence-associated reprogramming promotes cancer stemness.
Maja Milanovic, Dorothy N Y Fan, Dimitri Belenki, J Henry M Däbritz, Zhen Zhao, Yong Yu, Jan R Dörr, Lora Dimitrova, Dido Lenze, Ines A Monteiro Barbosa,[...]. Nature 2018
257
13

NOTCH1 mediates a switch between two distinct secretomes during senescence.
Matthew Hoare, Yoko Ito, Tae-Won Kang, Michael P Weekes, Nicholas J Matheson, Daniel A Patten, Shishir Shetty, Aled J Parry, Suraj Menon, Rafik Salama,[...]. Nat Cell Biol 2016
158
13

The senescence-associated secretory phenotype induces cellular plasticity and tissue regeneration.
Birgit Ritschka, Mekayla Storer, Alba Mas, Florian Heinzmann, Mari Carmen Ortells, Jennifer P Morton, Owen J Sansom, Lars Zender, William M Keyes. Genes Dev 2017
206
13

Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas.
Wen Xue, Lars Zender, Cornelius Miething, Ross A Dickins, Eva Hernando, Valery Krizhanovsky, Carlos Cordon-Cardo, Scott W Lowe. Nature 2007
13

Reversal of human cellular senescence: roles of the p53 and p16 pathways.
Christian M Beauséjour, Ana Krtolica, Francesco Galimi, Masashi Narita, Scott W Lowe, Paul Yaswen, Judith Campisi. EMBO J 2003
752
12

Control of the senescence-associated secretory phenotype by NF-κB promotes senescence and enhances chemosensitivity.
Yuchen Chien, Claudio Scuoppo, Xiaowo Wang, Xueping Fang, Brian Balgley, Jessica E Bolden, Prem Premsrirut, Weijun Luo, Agustin Chicas, Cheng S Lee,[...]. Genes Dev 2011
440
12

Cytoplasmic chromatin triggers inflammation in senescence and cancer.
Zhixun Dou, Kanad Ghosh, Maria Grazia Vizioli, Jiajun Zhu, Payel Sen, Kirk J Wangensteen, Johayra Simithy, Yemin Lan, Yanping Lin, Zhuo Zhou,[...]. Nature 2017
330
12

Senolytics improve physical function and increase lifespan in old age.
Ming Xu, Tamar Pirtskhalava, Joshua N Farr, Bettina M Weigand, Allyson K Palmer, Megan M Weivoda, Christina L Inman, Mikolaj B Ogrodnik, Christine M Hachfeld, Daniel G Fraser,[...]. Nat Med 2018
449
12

Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints.
Jirina Bartkova, Nousin Rezaei, Michalis Liontos, Panagiotis Karakaidos, Dimitris Kletsas, Natalia Issaeva, Leandros-Vassilios F Vassiliou, Evangelos Kolettas, Katerina Niforou, Vassilis C Zoumpourlis,[...]. Nature 2006
12

Mitochondrial Dysfunction Induces Senescence with a Distinct Secretory Phenotype.
Christopher D Wiley, Michael C Velarde, Pacome Lecot, Su Liu, Ethan A Sarnoski, Adam Freund, Kotaro Shirakawa, Hyung W Lim, Sonnet S Davis, Arvind Ramanathan,[...]. Cell Metab 2016
335
12


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.