A citation-based method for searching scientific literature

P J Morin, A B Sparks, V Korinek, N Barker, H Clevers, B Vogelstein, K W Kinzler. Science 1997
Times Cited: 3329







List of co-cited articles
619 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma.
V Korinek, N Barker, P J Morin, D van Wichen, R de Weger, K W Kinzler, B Vogelstein, H Clevers. Science 1997
20


Identification of c-MYC as a target of the APC pathway.
T C He, A B Sparks, C Rago, H Hermeking, L Zawel, L T da Costa, P J Morin, B Vogelstein, K W Kinzler. Science 1998
17

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.
Freddie Bray, Jacques Ferlay, Isabelle Soerjomataram, Rebecca L Siegel, Lindsey A Torre, Ahmedin Jemal. CA Cancer J Clin 2018
17


Identification of stem cells in small intestine and colon by marker gene Lgr5.
Nick Barker, Johan H van Es, Jeroen Kuipers, Pekka Kujala, Maaike van den Born, Miranda Cozijnsen, Andrea Haegebarth, Jeroen Korving, Harry Begthel, Peter J Peters,[...]. Nature 2007
13

Wnt/beta-catenin signaling: components, mechanisms, and diseases.
Bryan T MacDonald, Keiko Tamai, Xi He. Dev Cell 2009
11

A genetic model for colorectal tumorigenesis.
E R Fearon, B Vogelstein. Cell 1990
10

Wnt/β-catenin signaling and disease.
Hans Clevers, Roel Nusse. Cell 2012
10

Lessons from hereditary colorectal cancer.
K W Kinzler, B Vogelstein. Cell 1996
10


AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1.
S Satoh, Y Daigo, Y Furukawa, T Kato, N Miwa, T Nishiwaki, T Kawasoe, H Ishiguro, M Fujita, T Tokino,[...]. Nat Genet 2000
800
9

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling.
Shih-Min A Huang, Yuji M Mishina, Shanming Liu, Atwood Cheung, Frank Stegmeier, Gregory A Michaud, Olga Charlat, Elizabeth Wiellette, Yue Zhang, Stephanie Wiessner,[...]. Nature 2009
9


Stabilization of beta-catenin by genetic defects in melanoma cell lines.
B Rubinfeld, P Robbins, M El-Gamil, I Albert, E Porfiri, P Polakis. Science 1997
8

Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta.
J Behrens, B A Jerchow, M Würtele, J Grimm, C Asbrand, R Wirtz, M Kühl, D Wedlich, W Birchmeier. Science 1998
8

Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating beta-catenin/TCF signalling.
W Liu, X Dong, M Mai, R S Seelan, K Taniguchi, K K Krishnadath, K C Halling, J M Cunningham, L A Boardman, C Qian,[...]. Nat Genet 2000
391
8

Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer.
Hiromu Suzuki, D Neil Watkins, Kam-Wing Jair, Kornel E Schuebel, Sanford D Markowitz, Wei Dong Chen, Theresa P Pretlow, Bin Yang, Yoshimitsu Akiyama, Manon Van Engeland,[...]. Nat Genet 2004
826
7

The consensus molecular subtypes of colorectal cancer.
Justin Guinney, Rodrigo Dienstmann, Xin Wang, Aurélien de Reyniès, Andreas Schlicker, Charlotte Soneson, Laetitia Marisa, Paul Roepman, Gift Nyamundanda, Paolo Angelino,[...]. Nat Med 2015
7

Wnt signalling and its impact on development and cancer.
Alexandra Klaus, Walter Birchmeier. Nat Rev Cancer 2008
6

Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors.
Barbara Lustig, Boris Jerchow, Martin Sachs, Sigrid Weiler, Torsten Pietsch, Uwe Karsten, Marc van de Wetering, Hans Clevers, Peter M Schlag, Walter Birchmeier,[...]. Mol Cell Biol 2002
776
6



Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche.
Toshiro Sato, Robert G Vries, Hugo J Snippert, Marc van de Wetering, Nick Barker, Daniel E Stange, Johan H van Es, Arie Abo, Pekka Kujala, Peter J Peters,[...]. Nature 2009
6

Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer.
Baozhi Chen, Michael E Dodge, Wei Tang, Jianming Lu, Zhiqiang Ma, Chih-Wei Fan, Shuguang Wei, Wayne Hao, Jessica Kilgore, Noelle S Williams,[...]. Nat Chem Biol 2009
988
6


The many faces and functions of β-catenin.
Tomas Valenta, George Hausmann, Konrad Basler. EMBO J 2012
827
6

The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells.
Marc van de Wetering, Elena Sancho, Cornelis Verweij, Wim de Lau, Irma Oving, Adam Hurlstone, Karin van der Horn, Eduard Batlle, Damien Coudreuse, Anna Pavlina Haramis,[...]. Cell 2002
6

Functional interaction of beta-catenin with the transcription factor LEF-1.
J Behrens, J P von Kries, M Kühl, L Bruhn, D Wedlich, R Grosschedl, W Birchmeier. Nature 1996
6

Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly.
B Rubinfeld, I Albert, E Porfiri, C Fiol, S Munemitsu, P Polakis. Science 1996
6

XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos.
M Molenaar, M van de Wetering, M Oosterwegel, J Peterson-Maduro, S Godsave, V Korinek, J Roose, O Destrée, H Clevers. Cell 1996
6


The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway.
M Shtutman, J Zhurinsky, I Simcha, C Albanese, M D'Amico, R Pestell, A Ben-Ze'ev. Proc Natl Acad Sci U S A 1999
5

The Wnt signaling pathway in development and disease.
Catriona Y Logan, Roel Nusse. Annu Rev Cell Dev Biol 2004
5

beta-catenin is a target for the ubiquitin-proteasome pathway.
H Aberle, A Bauer, J Stappert, A Kispert, R Kemler. EMBO J 1997
5

CTNNB1 (beta-catenin) mutation identifies low grade, early stage endometrial cancer patients at increased risk of recurrence.
Katherine C Kurnit, Grace N Kim, Bryan M Fellman, Diana L Urbauer, Gordon B Mills, Wei Zhang, Russell R Broaddus. Mod Pathol 2017
90
5

WNT signalling pathways as therapeutic targets in cancer.
Jamie N Anastas, Randall T Moon. Nat Rev Cancer 2013
5

The ABC of APC.
N S Fearnhead, M P Britton, W F Bodmer. Hum Mol Genet 2001
617
5

Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α.
Curtis A Thorne, Alison J Hanson, Judsen Schneider, Emilios Tahinci, Darren Orton, Christopher S Cselenyi, Kristin K Jernigan, Kelly C Meyers, Brian I Hang, Alex G Waterson,[...]. Nat Chem Biol 2010
315
5

Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway.
Sharon Amit, Ada Hatzubai, Yaara Birman, Jens S Andersen, Etti Ben-Shushan, Matthias Mann, Yinon Ben-Neriah, Irit Alkalay. Genes Dev 2002
528
5

Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974.
Jun Liu, Shifeng Pan, Mindy H Hsieh, Nicholas Ng, Fangxian Sun, Tao Wang, Shailaja Kasibhatla, Alwin G Schuller, Allen G Li, Dai Cheng,[...]. Proc Natl Acad Sci U S A 2013
453
5


Frizzled-7 Is Required for Wnt Signaling in Gastric Tumors with and Without Apc Mutations.
Dustin J Flanagan, Nick Barker, Natasha S Di Costanzo, Elizabeth A Mason, Austin Gurney, Valerie S Meniel, Sarah Koushyar, Chloe R Austin, Matthias Ernst, Helen B Pearson,[...]. Cancer Res 2019
32
15

Wnt pathway inhibition via the targeting of Frizzled receptors results in decreased growth and tumorigenicity of human tumors.
Austin Gurney, Fumiko Axelrod, Christopher J Bond, Jennifer Cain, Cecile Chartier, Lucas Donigan, Marcus Fischer, Aurélie Chaudhari, May Ji, Ann M Kapoun,[...]. Proc Natl Acad Sci U S A 2012
337
5

Wnt signaling in cancer.
Paul Polakis. Cold Spring Harb Perspect Biol 2012
573
5

APC mutations occur early during colorectal tumorigenesis.
S M Powell, N Zilz, Y Beazer-Barclay, T M Bryan, S R Hamilton, S N Thibodeau, B Vogelstein, K W Kinzler. Nature 1992
5

Identification and characterization of the familial adenomatous polyposis coli gene.
J Groden, A Thliveris, W Samowitz, M Carlson, L Gelbert, H Albertsen, G Joslyn, J Stevens, L Spirio, M Robertson. Cell 1991
5

Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4.
V Korinek, N Barker, P Moerer, E van Donselaar, G Huls, P J Peters, H Clevers. Nat Genet 1998
5

A critical role for the Wnt effector Tcf4 in adult intestinal homeostatic self-renewal.
Johan H van Es, Andrea Haegebarth, Pekka Kujala, Shalev Itzkovitz, Bon-Kyoung Koo, Sylvia F Boj, Jeroen Korving, Maaike van den Born, Alexander van Oudenaarden, Sylvie Robine,[...]. Mol Cell Biol 2012
160
5

The β-catenin destruction complex.
Jennifer L Stamos, William I Weis. Cold Spring Harb Perspect Biol 2013
528
5


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.