A citation-based method for searching scientific literature

P J Conn, J P Pin. Annu Rev Pharmacol Toxicol 1997
Times Cited: 2471







List of co-cited articles
848 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Metabotropic glutamate receptors: physiology, pharmacology, and disease.
Colleen M Niswender, P Jeffrey Conn. Annu Rev Pharmacol Toxicol 2010
40

Glutamate receptor ion channels: structure, regulation, and function.
Stephen F Traynelis, Lonnie P Wollmuth, Chris J McBain, Frank S Menniti, Katie M Vance, Kevin K Ogden, Kasper B Hansen, Hongjie Yuan, Scott J Myers, Ray Dingledine. Pharmacol Rev 2010
13

The metabotropic glutamate receptors: structure and functions.
J P Pin, R Duvoisin. Neuropharmacology 1995
11


Metabotropic glutamate receptors: from the workbench to the bedside.
F Nicoletti, J Bockaert, G L Collingridge, P J Conn, F Ferraguti, D D Schoepp, J T Wroblewski, J P Pin. Neuropharmacology 2011
414
10

Structural insights into the activation of metabotropic glutamate receptors.
Antoine Koehl, Hongli Hu, Dan Feng, Bingfa Sun, Yan Zhang, Michael J Robertson, Matthew Chu, Tong Sun Kobilka, Toon Laeremans, Jan Steyaert,[...]. Nature 2019
132
10


Development of allosteric modulators of GPCRs for treatment of CNS disorders.
Hilary Highfield Nickols, P Jeffrey Conn. Neurobiol Dis 2014
149
8

Metabotropic glutamate receptors as novel targets for anxiety and stress disorders.
Chad J Swanson, Mark Bures, Michael P Johnson, Anni-Maija Linden, James A Monn, Darryle D Schoepp. Nat Rev Drug Discov 2005
462
8

Metabotropic glutamate receptors.
Francesco Ferraguti, Ryuichi Shigemoto. Cell Tissue Res 2006
355
8


Glutamate uptake.
N C Danbolt. Prog Neurobiol 2001
7

Coupling of mGluR/Homer and PSD-95 complexes by the Shank family of postsynaptic density proteins.
J C Tu, B Xiao, S Naisbitt, J P Yuan, R S Petralia, P Brakeman, A Doan, V K Aakalu, A A Lanahan, M Sheng,[...]. Neuron 1999
810
7


Metabotropic glutamate receptors and neurodegenerative diseases.
Fabiola M Ribeiro, Luciene B Vieira, Rita G W Pires, Roenick P Olmo, Stephen S G Ferguson. Pharmacol Res 2017
106
7

Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor.
N Kunishima, Y Shimada, Y Tsuji, T Sato, M Yamamoto, T Kumasaka, S Nakanishi, H Jingami, K Morikawa. Nature 2000
932
7

Role of Metabotropic Glutamate Receptors in Neurological Disorders.
Rosalia Crupi, Daniela Impellizzeri, Salvatore Cuzzocrea. Front Mol Neurosci 2019
70
10

Immunohistochemical localization of a metabotropic glutamate receptor, mGluR5, in the rat brain.
R Shigemoto, S Nomura, H Ohishi, H Sugihara, S Nakanishi, N Mizuno. Neurosci Lett 1993
452
7

Localization of neuronal and glial glutamate transporters.
J D Rothstein, L Martin, A I Levey, M Dykes-Hoberg, L Jin, D Wu, N Nash, R W Kuncl. Neuron 1994
6

Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain.
Andrew S Doré, Krzysztof Okrasa, Jayesh C Patel, Maria Serrano-Vega, Kirstie Bennett, Robert M Cooke, James C Errey, Ali Jazayeri, Samir Khan, Ben Tehan,[...]. Nature 2014
289
6

Distribution of metabotropic glutamate receptor mGluR5 immunoreactivity in rat brain.
C Romano, M A Sesma, C T McDonald, K O'Malley, A N Van den Pol, J W Olney. J Comp Neurol 1995
562
6

Differential presynaptic localization of metabotropic glutamate receptor subtypes in the rat hippocampus.
R Shigemoto, A Kinoshita, E Wada, S Nomura, H Ohishi, M Takada, P J Flor, A Neki, T Abe, S Nakanishi,[...]. J Neurosci 1997
848
6



Pharmacological agents acting at subtypes of metabotropic glutamate receptors.
D D Schoepp, D E Jane, J A Monn. Neuropharmacology 1999
878
6

Targeting metabotropic glutamate receptors for novel treatments of schizophrenia.
James Maksymetz, Sean P Moran, P Jeffrey Conn. Mol Brain 2017
69
8

Selective actions of novel allosteric modulators reveal functional heteromers of metabotropic glutamate receptors in the CNS.
Shen Yin, Meredith J Noetzel, Kari A Johnson, Rocio Zamorano, Nidhi Jalan-Sakrikar, Karen J Gregory, P Jeffrey Conn, Colleen M Niswender. J Neurosci 2014
80
7


Discovery, characterization, and antiparkinsonian effect of novel positive allosteric modulators of metabotropic glutamate receptor 4.
Colleen M Niswender, Kari A Johnson, C David Weaver, Carrie K Jones, Zixiu Xiang, Qingwei Luo, Alice L Rodriguez, Joy E Marlo, Tomas de Paulis, Analisa D Thompson,[...]. Mol Pharmacol 2008
154
6

Trends in GPCR drug discovery: new agents, targets and indications.
Alexander S Hauser, Misty M Attwood, Mathias Rask-Andersen, Helgi B Schiöth, David E Gloriam. Nat Rev Drug Discov 2017
934
6

Metabotropic glutamate receptor-mediated long-term depression: molecular mechanisms.
Clare M Gladding, Stephen M Fitzjohn, Elek Molnár. Pharmacol Rev 2009
153
6

Efficacy and Safety of Basimglurant as Adjunctive Therapy for Major Depression: A Randomized Clinical Trial.
Jorge A Quiroz, Paul Tamburri, Dennis Deptula, Ludger Banken, Ulrich Beyer, Michael Rabbia, Nikhat Parkar, Paulo Fontoura, Luca Santarelli. JAMA Psychiatry 2016
77
6

The therapeutic potential of metabotropic glutamate receptor modulation for schizophrenia.
Branden J Stansley, P Jeffrey Conn. Curr Opin Pharmacol 2018
31
16

Blocking metabotropic glutamate receptor subtype 7 (mGlu7) via the Venus flytrap domain (VFTD) inhibits amygdala plasticity, stress, and anxiety-related behavior.
Christine E Gee, Daniel Peterlik, Christoph Neuhäuser, Rochdi Bouhelal, Klemens Kaupmann, Grit Laue, Nicole Uschold-Schmidt, Dominik Feuerbach, Kaspar Zimmermann, Silvio Ofner,[...]. J Biol Chem 2014
48
10

Investigating metabotropic glutamate receptor 5 allosteric modulator cooperativity, affinity, and agonism: enriching structure-function studies and structure-activity relationships.
Karen J Gregory, Meredith J Noetzel, Jerri M Rook, Paige N Vinson, Shaun R Stauffer, Alice L Rodriguez, Kyle A Emmitte, Ya Zhou, Aspen C Chun, Andrew S Felts,[...]. Mol Pharmacol 2012
67
7

A selective metabotropic glutamate receptor 7 agonist: activation of receptor signaling via an allosteric site modulates stress parameters in vivo.
Kayo Mitsukawa, Rina Yamamoto, Silvio Ofner, Joachim Nozulak, Oliver Pescott, Snezana Lukic, Natacha Stoehr, Cedric Mombereau, Rainer Kuhn, Kevin H McAllister,[...]. Proc Natl Acad Sci U S A 2005
195
5


A potent and selective metabotropic glutamate receptor 4 positive allosteric modulator improves movement in rodent models of Parkinson's disease.
Emmanuel Le Poul, Christelle Boléa, Francoise Girard, Sonia Poli, Delphine Charvin, Brice Campo, Julien Bortoli, Abdhelak Bessif, Bin Luo, Amy Jo Koser,[...]. J Pharmacol Exp Ther 2012
66
7

Allosteric modulation of group III metabotropic glutamate receptor 4: a potential approach to Parkinson's disease treatment.
Michael J Marino, David L Williams, Julie A O'Brien, Ornella Valenti, Terrence P McDonald, Michelle K Clements, Ruiping Wang, Anthony G DiLella, J Fred Hess, Gene G Kinney,[...]. Proc Natl Acad Sci U S A 2003
192
5



Mechanism of Assembly and Cooperativity of Homomeric and Heteromeric Metabotropic Glutamate Receptors.
Joshua Levitz, Chris Habrian, Shashank Bharill, Zhu Fu, Reza Vafabakhsh, Ehud Y Isacoff. Neuron 2016
89
5

Structures of the extracellular regions of the group II/III metabotropic glutamate receptors.
Takanori Muto, Daisuke Tsuchiya, Kosuke Morikawa, Hisato Jingami. Proc Natl Acad Sci U S A 2007
265
5

The metabotropic glutamate receptor 4-positive allosteric modulator VU0364770 produces efficacy alone and in combination with L-DOPA or an adenosine 2A antagonist in preclinical rodent models of Parkinson's disease.
Carrie K Jones, Michael Bubser, Analisa D Thompson, Jonathan W Dickerson, Nathalie Turle-Lorenzo, Marianne Amalric, Anna L Blobaum, Thomas M Bridges, Ryan D Morrison, Satyawan Jadhav,[...]. J Pharmacol Exp Ther 2012
74
6

Development and Antiparkinsonian Activity of VU0418506, a Selective Positive Allosteric Modulator of Metabotropic Glutamate Receptor 4 Homomers without Activity at mGlu2/4 Heteromers.
Colleen M Niswender, Carrie K Jones, Xin Lin, Michael Bubser, Analisa Thompson Gray, Anna L Blobaum, Darren W Engers, Alice L Rodriguez, Matthew T Loch, J Scott Daniels,[...]. ACS Chem Neurosci 2016
38
13



Evolution, structure, and activation mechanism of family 3/C G-protein-coupled receptors.
Jean-Philippe Pin, Thierry Galvez, Laurent Prézeau. Pharmacol Ther 2003
449
5




Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.