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Times Cited: 764
Times Cited: 764
Times Cited
Times Co-cited
Similarity
Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1.
L Li, I D Krantz, Y Deng, A Genin, A B Banta, C C Collins, M Qi, B J Trask, W L Kuo, J Cochran,[...]. Nat Genet 1997
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NOTCH2 mutations cause Alagille syndrome, a heterogeneous disorder of the notch signaling pathway.
Ryan McDaniell, Daniel M Warthen, Pedro A Sanchez-Lara, Athma Pai, Ian D Krantz, David A Piccoli, Nancy B Spinner. Am J Hum Genet 2006
Ryan McDaniell, Daniel M Warthen, Pedro A Sanchez-Lara, Athma Pai, Ian D Krantz, David A Piccoli, Nancy B Spinner. Am J Hum Genet 2006
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Features of Alagille syndrome in 92 patients: frequency and relation to prognosis.
K M Emerick, E B Rand, E Goldmuntz, I D Krantz, N B Spinner, D A Piccoli. Hepatology 1999
K M Emerick, E B Rand, E Goldmuntz, I D Krantz, N B Spinner, D A Piccoli. Hepatology 1999
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NOTCH2 mutations in Alagille syndrome.
Binita Maya Kamath, Robert C Bauer, Kathleen M Loomes, Grace Chao, Jennifer Gerfen, Anne Hutchinson, Winita Hardikar, Gideon Hirschfield, Paloma Jara, Ian D Krantz,[...]. J Med Genet 2012
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Jagged1 in the portal vein mesenchyme regulates intrahepatic bile duct development: insights into Alagille syndrome.
Jennifer J Hofmann, Ann C Zovein, Huilin Koh, Freddy Radtke, Gerry Weinmaster, M Luisa Iruela-Arispe. Development 2010
Jennifer J Hofmann, Ann C Zovein, Huilin Koh, Freddy Radtke, Gerry Weinmaster, M Luisa Iruela-Arispe. Development 2010
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Alagille syndrome: pathogenesis, diagnosis and management.
Peter D Turnpenny, Sian Ellard. Eur J Hum Genet 2012
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Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1.
Y Xue, X Gao, C E Lindsell, C R Norton, B Chang, C Hicks, M Gendron-Maguire, E B Rand, G Weinmaster, T Gridley. Hum Mol Genet 1999
Y Xue, X Gao, C E Lindsell, C R Norton, B Chang, C Hicks, M Gendron-Maguire, E B Rand, G Weinmaster, T Gridley. Hum Mol Genet 1999
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Notch signaling controls liver development by regulating biliary differentiation.
Yiwei Zong, Archana Panikkar, Jie Xu, Aline Antoniou, Peggy Raynaud, Frederic Lemaigre, Ben Z Stanger. Development 2009
Yiwei Zong, Archana Panikkar, Jie Xu, Aline Antoniou, Peggy Raynaud, Frederic Lemaigre, Ben Z Stanger. Development 2009
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Jagged1 heterozygosity in mice results in a congenital cholangiopathy which is reversed by concomitant deletion of one copy of Poglut1 (Rumi).
Shakeel M Thakurdas, Mario F Lopez, Shinako Kakuda, Rodrigo Fernandez-Valdivia, Neda Zarrin-Khameh, Robert S Haltiwanger, Hamed Jafar-Nejad. Hepatology 2016
Shakeel M Thakurdas, Mario F Lopez, Shinako Kakuda, Rodrigo Fernandez-Valdivia, Neda Zarrin-Khameh, Robert S Haltiwanger, Hamed Jafar-Nejad. Hepatology 2016
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Hepatic ductular hypoplasia associated with characteristic facies, vertebral malformations, retarded physical, mental, and sexual development, and cardiac murmur.
D Alagille, M Odièvre, M Gautier, J P Dommergues. J Pediatr 1975
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A mouse model of Alagille syndrome: Notch2 as a genetic modifier of Jag1 haploinsufficiency.
Brent McCright, Julie Lozier, Thomas Gridley. Development 2002
Brent McCright, Julie Lozier, Thomas Gridley. Development 2002
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Mouse Model of Alagille Syndrome and Mechanisms of Jagged1 Missense Mutations.
Emma R Andersson, Indira V Chivukula, Simona Hankeova, Marika Sjöqvist, Yat Long Tsoi, Daniel Ramsköld, Jan Masek, Aiman Elmansuri, Anita Hoogendoorn, Elenae Vazquez,[...]. Gastroenterology 2018
Emma R Andersson, Indira V Chivukula, Simona Hankeova, Marika Sjöqvist, Yat Long Tsoi, Daniel Ramsköld, Jan Masek, Aiman Elmansuri, Anita Hoogendoorn, Elenae Vazquez,[...]. Gastroenterology 2018
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Syndromic paucity of interlobular bile ducts (Alagille syndrome or arteriohepatic dysplasia): review of 80 cases.
D Alagille, A Estrada, M Hadchouel, M Gautier, M Odièvre, J P Dommergues. J Pediatr 1987
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The canonical Notch signaling pathway: unfolding the activation mechanism.
Raphael Kopan, Maria Xenia G Ilagan. Cell 2009
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15
Intrahepatic bile ducts develop according to a new mode of tubulogenesis regulated by the transcription factor SOX9.
Aline Antoniou, Peggy Raynaud, Sabine Cordi, Yiwei Zong, François Tronche, Ben Z Stanger, Patrick Jacquemin, Christophe E Pierreux, Frederic Clotman, Frederic P Lemaigre. Gastroenterology 2009
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14
Vascular anomalies in Alagille syndrome: a significant cause of morbidity and mortality.
Binita M Kamath, Nancy B Spinner, Karan M Emerick, Albert E Chudley, Carol Booth, David A Piccoli, Ian D Krantz. Circulation 2004
Binita M Kamath, Nancy B Spinner, Karan M Emerick, Albert E Chudley, Carol Booth, David A Piccoli, Ian D Krantz. Circulation 2004
14
13
Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia.
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13
De novo formation of the biliary system by TGFβ-mediated hepatocyte transdifferentiation.
Johanna R Schaub, Kari A Huppert, Simone N T Kurial, Bernadette Y Hsu, Ashley E Cast, Bryan Donnelly, Rebekah A Karns, Feng Chen, Milad Rezvani, Hubert Y Luu,[...]. Nature 2018
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13
Alagille syndrome mutation update: Comprehensive overview of JAG1 and NOTCH2 mutation frequencies and insight into missense variant classification.
Melissa A Gilbert, Robert C Bauer, Ramakrishnan Rajagopalan, Christopher M Grochowski, Grace Chao, Deborah McEldrew, James A Nassur, Elizabeth B Rand, Bryan L Krock, Binita M Kamath,[...]. Hum Mutat 2019
Melissa A Gilbert, Robert C Bauer, Ramakrishnan Rajagopalan, Christopher M Grochowski, Grace Chao, Deborah McEldrew, James A Nassur, Elizabeth B Rand, Bryan L Krock, Binita M Kamath,[...]. Hum Mutat 2019
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Intrahepatic bile duct regeneration in mice does not require Hnf6 or Notch signaling through Rbpj.
Teagan J Walter, Charles Vanderpool, Ashley E Cast, Stacey S Huppert. Am J Pathol 2014
Teagan J Walter, Charles Vanderpool, Ashley E Cast, Stacey S Huppert. Am J Pathol 2014
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Notch signaling controls hepatoblast differentiation by altering the expression of liver-enriched transcription factors.
Naoki Tanimizu, Atsushi Miyajima. J Cell Sci 2004
Naoki Tanimizu, Atsushi Miyajima. J Cell Sci 2004
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Liver-specific inactivation of Notch2, but not Notch1, compromises intrahepatic bile duct development in mice.
Fabian Geisler, Florian Nagl, Pawel K Mazur, Marcel Lee, Ursula Zimber-Strobl, Lothar J Strobl, Freddy Radtke, Roland M Schmid, Jens T Siveke. Hepatology 2008
Fabian Geisler, Florian Nagl, Pawel K Mazur, Marcel Lee, Ursula Zimber-Strobl, Lothar J Strobl, Freddy Radtke, Roland M Schmid, Jens T Siveke. Hepatology 2008
11
Bile duct proliferation in Jag1/fringe heterozygous mice identifies candidate modifiers of the Alagille syndrome hepatic phenotype.
Matthew J Ryan, Christina Bales, Anthony Nelson, Dorian M Gonzalez, Lara Underkoffler, Michelle Segalov, Jeanne Wilson-Rawls, Susan E Cole, Jennifer L Moran, Pierre Russo,[...]. Hepatology 2008
Matthew J Ryan, Christina Bales, Anthony Nelson, Dorian M Gonzalez, Lara Underkoffler, Michelle Segalov, Jeanne Wilson-Rawls, Susan E Cole, Jennifer L Moran, Pierre Russo,[...]. Hepatology 2008
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Notch signaling: simplicity in design, versatility in function.
Emma R Andersson, Rickard Sandberg, Urban Lendahl. Development 2011
Emma R Andersson, Rickard Sandberg, Urban Lendahl. Development 2011
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Spectrum and frequency of jagged1 (JAG1) mutations in Alagille syndrome patients and their families.
I D Krantz, R P Colliton, A Genin, E B Rand, L Li, D A Piccoli, N B Spinner. Am J Hum Genet 1998
I D Krantz, R P Colliton, A Genin, E B Rand, L Li, D A Piccoli, N B Spinner. Am J Hum Genet 1998
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Consequences of JAG1 mutations.
B M Kamath, L Bason, D A Piccoli, I D Krantz, N B Spinner. J Med Genet 2003
B M Kamath, L Bason, D A Piccoli, I D Krantz, N B Spinner. J Med Genet 2003
10
The role of notch signaling in the development of intrahepatic bile ducts.
Yuzo Kodama, Makoto Hijikata, Ryoichiro Kageyama, Kunitada Shimotohno, Tsutomu Chiba. Gastroenterology 2004
Yuzo Kodama, Makoto Hijikata, Ryoichiro Kageyama, Kunitada Shimotohno, Tsutomu Chiba. Gastroenterology 2004
10
10
Notch signaling: cell fate control and signal integration in development.
S Artavanis-Tsakonas, M D Rand, R J Lake. Science 1999
S Artavanis-Tsakonas, M D Rand, R J Lake. Science 1999
10
Mutations in NOTCH1 cause aortic valve disease.
Vidu Garg, Alecia N Muth, Joshua F Ransom, Marie K Schluterman, Robert Barnes, Isabelle N King, Paul D Grossfeld, Deepak Srivastava. Nature 2005
Vidu Garg, Alecia N Muth, Joshua F Ransom, Marie K Schluterman, Robert Barnes, Isabelle N King, Paul D Grossfeld, Deepak Srivastava. Nature 2005
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Systematic Review: The Epidemiology, Natural History, and Burden of Alagille Syndrome.
Binita M Kamath, Alastair Baker, Roderick Houwen, Lora Todorova, Nanda Kerkar. J Pediatr Gastroenterol Nutr 2018
Binita M Kamath, Alastair Baker, Roderick Houwen, Lora Todorova, Nanda Kerkar. J Pediatr Gastroenterol Nutr 2018
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The notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis.
Rui Benedito, Cristina Roca, Inga Sörensen, Susanne Adams, Achim Gossler, Marcus Fruttiger, Ralf H Adams. Cell 2009
Rui Benedito, Cristina Roca, Inga Sörensen, Susanne Adams, Achim Gossler, Marcus Fruttiger, Ralf H Adams. Cell 2009
10
Analysis of cardiovascular phenotype and genotype-phenotype correlation in individuals with a JAG1 mutation and/or Alagille syndrome.
Doff B McElhinney, Ian D Krantz, Lynn Bason, David A Piccoli, Karan M Emerick, Nancy B Spinner, Elizabeth Goldmuntz. Circulation 2002
Doff B McElhinney, Ian D Krantz, Lynn Bason, David A Piccoli, Karan M Emerick, Nancy B Spinner, Elizabeth Goldmuntz. Circulation 2002
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Long-term culture of genome-stable bipotent stem cells from adult human liver.
Meritxell Huch, Helmuth Gehart, Ruben van Boxtel, Karien Hamer, Francis Blokzijl, Monique M A Verstegen, Ewa Ellis, Martien van Wenum, Sabine A Fuchs, Joep de Ligt,[...]. Cell 2015
Meritxell Huch, Helmuth Gehart, Ruben van Boxtel, Karien Hamer, Francis Blokzijl, Monique M A Verstegen, Ewa Ellis, Martien van Wenum, Sabine A Fuchs, Joep de Ligt,[...]. Cell 2015
9
Bile duct proliferation in liver-specific Jag1 conditional knockout mice: effects of gene dosage.
Kathleen M Loomes, Pierre Russo, Matthew Ryan, Anthony Nelson, Lara Underkoffler, Curtis Glover, Hong Fu, Thomas Gridley, Klaus H Kaestner, Rebecca J Oakey. Hepatology 2007
Kathleen M Loomes, Pierre Russo, Matthew Ryan, Anthony Nelson, Lara Underkoffler, Curtis Glover, Hong Fu, Thomas Gridley, Klaus H Kaestner, Rebecca J Oakey. Hepatology 2007
14
Notch signaling regulates formation of the three-dimensional architecture of intrahepatic bile ducts in mice.
Erin E Sparks, Kari A Huppert, Melanie A Brown, M Kay Washington, Stacey S Huppert. Hepatology 2010
Erin E Sparks, Kari A Huppert, Melanie A Brown, M Kay Washington, Stacey S Huppert. Hepatology 2010
10
Jagged1 (JAG1) mutations in Alagille syndrome: increasing the mutation detection rate.
D M Warthen, E C Moore, B M Kamath, J J D Morrissette, P A Sanchez-Lara, D A Piccoli, I D Krantz, N B Spinner. Hum Mutat 2006
D M Warthen, E C Moore, B M Kamath, J J D Morrissette, P A Sanchez-Lara, D A Piccoli, I D Krantz, N B Spinner. Hum Mutat 2006
9
Mutations in NOTCH1 cause Adams-Oliver syndrome.
Anna-Barbara Stittrich, Anna Lehman, Dale L Bodian, Justin Ashworth, Zheyuan Zong, Hong Li, Patricia Lam, Alina Khromykh, Ramaswamy K Iyer, Joseph G Vockley,[...]. Am J Hum Genet 2014
Anna-Barbara Stittrich, Anna Lehman, Dale L Bodian, Justin Ashworth, Zheyuan Zong, Hong Li, Patricia Lam, Alina Khromykh, Ramaswamy K Iyer, Joseph G Vockley,[...]. Am J Hum Genet 2014
9
Hippo pathway activity influences liver cell fate.
Dean Yimlamai, Constantina Christodoulou, Giorgio G Galli, Kilangsungla Yanger, Brian Pepe-Mooney, Basanta Gurung, Kriti Shrestha, Patrick Cahan, Ben Z Stanger, Fernando D Camargo. Cell 2014
Dean Yimlamai, Constantina Christodoulou, Giorgio G Galli, Kilangsungla Yanger, Brian Pepe-Mooney, Basanta Gurung, Kriti Shrestha, Patrick Cahan, Ben Z Stanger, Fernando D Camargo. Cell 2014
9
Congenital heart disease caused by mutations in the transcription factor NKX2-5.
J J Schott, D W Benson, C T Basson, W Pease, G M Silberbach, J P Moak, B J Maron, C E Seidman, J G Seidman. Science 1998
J J Schott, D W Benson, C T Basson, W Pease, G M Silberbach, J P Moak, B J Maron, C E Seidman, J G Seidman. Science 1998
8
Cranial neural crest ablation of Jagged1 recapitulates the craniofacial phenotype of Alagille syndrome patients.
Ryan Humphreys, Wei Zheng, Lawrence S Prince, Xianghu Qu, Christopher Brown, Kathleen Loomes, Stacey S Huppert, Scott Baldwin, Steven Goudy. Hum Mol Genet 2012
Ryan Humphreys, Wei Zheng, Lawrence S Prince, Xianghu Qu, Christopher Brown, Kathleen Loomes, Stacey S Huppert, Scott Baldwin, Steven Goudy. Hum Mol Genet 2012
16
Control of Notch-ligand endocytosis by ligand-receptor interaction.
Emil M Hansson, Fredrik Lanner, Debashish Das, Anders Mutvei, Ulrika Marklund, Johan Ericson, Filip Farnebo, Gabriele Stumm, Harald Stenmark, Emma R Andersson,[...]. J Cell Sci 2010
Emil M Hansson, Fredrik Lanner, Debashish Das, Anders Mutvei, Ulrika Marklund, Johan Ericson, Filip Farnebo, Gabriele Stumm, Harald Stenmark, Emma R Andersson,[...]. J Cell Sci 2010
15
Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning.
Farah A Falix, Víola B Weeda, Wilhelmina T Labruyere, Alexis Poncy, Dirk R de Waart, Theodorus B M Hakvoort, Frédéric Lemaigre, Ingrid C Gaemers, Daniël C Aronson, Wouter H Lamers. Dev Biol 2014
Farah A Falix, Víola B Weeda, Wilhelmina T Labruyere, Alexis Poncy, Dirk R de Waart, Theodorus B M Hakvoort, Frédéric Lemaigre, Ingrid C Gaemers, Daniël C Aronson, Wouter H Lamers. Dev Biol 2014
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Canonical Notch2 signaling determines biliary cell fates of embryonic hepatoblasts and adult hepatocytes independent of Hes1.
Petia Jeliazkova, Simone Jörs, Marcel Lee, Ursula Zimber-Strobl, Jorge Ferrer, Roland M Schmid, Jens T Siveke, Fabian Geisler. Hepatology 2013
Petia Jeliazkova, Simone Jörs, Marcel Lee, Ursula Zimber-Strobl, Jorge Ferrer, Roland M Schmid, Jens T Siveke, Fabian Geisler. Hepatology 2013
12
Analysis of liver repair mechanisms in Alagille syndrome and biliary atresia reveals a role for notch signaling.
Luca Fabris, Massimiliano Cadamuro, Maria Guido, Carlo Spirli, Romina Fiorotto, Michele Colledan, Giuliano Torre, Daniele Alberti, Aurelio Sonzogni, Lajos Okolicsanyi,[...]. Am J Pathol 2007
Luca Fabris, Massimiliano Cadamuro, Maria Guido, Carlo Spirli, Romina Fiorotto, Michele Colledan, Giuliano Torre, Daniele Alberti, Aurelio Sonzogni, Lajos Okolicsanyi,[...]. Am J Pathol 2007
9
Intrahepatic bile ducts are developed through formation of homogeneous continuous luminal network and its dynamic rearrangement in mice.
Naoki Tanimizu, Kota Kaneko, Tohru Itoh, Norihisa Ichinohe, Masayuki Ishii, Toru Mizuguchi, Koichi Hirata, Atsushi Miyajima, Toshihiro Mitaka. Hepatology 2016
Naoki Tanimizu, Kota Kaneko, Tohru Itoh, Norihisa Ichinohe, Masayuki Ishii, Toru Mizuguchi, Koichi Hirata, Atsushi Miyajima, Toshihiro Mitaka. Hepatology 2016
24
Transcription factors SOX4 and SOX9 cooperatively control development of bile ducts.
Alexis Poncy, Aline Antoniou, Sabine Cordi, Christophe E Pierreux, Patrick Jacquemin, Frédéric P Lemaigre. Dev Biol 2015
Alexis Poncy, Aline Antoniou, Sabine Cordi, Christophe E Pierreux, Patrick Jacquemin, Frédéric P Lemaigre. Dev Biol 2015
12
Heterozygous Loss-of-Function Mutations in DLL4 Cause Adams-Oliver Syndrome.
Josephina A N Meester, Laura Southgate, Anna-Barbara Stittrich, Hanka Venselaar, Sander J A Beekmans, Nicolette den Hollander, Emilia K Bijlsma, Appolonia Helderman-van den Enden, Joke B G M Verheij, Gustavo Glusman,[...]. Am J Hum Genet 2015
Josephina A N Meester, Laura Southgate, Anna-Barbara Stittrich, Hanka Venselaar, Sander J A Beekmans, Nicolette den Hollander, Emilia K Bijlsma, Appolonia Helderman-van den Enden, Joke B G M Verheij, Gustavo Glusman,[...]. Am J Hum Genet 2015
14
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.