D Bonnet, J E Dick. Nat Med 1997
Times Cited: 4680
Times Cited: 4680
Times Cited
Times Co-cited
Similarity
A cell initiating human acute myeloid leukaemia after transplantation into SCID mice.
T Lapidot, C Sirard, J Vormoor, B Murdoch, T Hoang, J Caceres-Cortes, M Minden, B Paterson, M A Caligiuri, J E Dick. Nature 1994
T Lapidot, C Sirard, J Vormoor, B Murdoch, T Hoang, J Caceres-Cortes, M Minden, B Paterson, M A Caligiuri, J E Dick. Nature 1994
42
Prospective identification of tumorigenic breast cancer cells.
Muhammad Al-Hajj, Max S Wicha, Adalberto Benito-Hernandez, Sean J Morrison, Michael F Clarke. Proc Natl Acad Sci U S A 2003
Muhammad Al-Hajj, Max S Wicha, Adalberto Benito-Hernandez, Sean J Morrison, Michael F Clarke. Proc Natl Acad Sci U S A 2003
39
Identification and expansion of human colon-cancer-initiating cells.
Lucia Ricci-Vitiani, Dario G Lombardi, Emanuela Pilozzi, Mauro Biffoni, Matilde Todaro, Cesare Peschle, Ruggero De Maria. Nature 2007
Lucia Ricci-Vitiani, Dario G Lombardi, Emanuela Pilozzi, Mauro Biffoni, Matilde Todaro, Cesare Peschle, Ruggero De Maria. Nature 2007
18
15
The epithelial-mesenchymal transition generates cells with properties of stem cells.
Sendurai A Mani, Wenjun Guo, Mai-Jing Liao, Elinor Ng Eaton, Ayyakkannu Ayyanan, Alicia Y Zhou, Mary Brooks, Ferenc Reinhard, Cheng Cheng Zhang, Michail Shipitsin,[...]. Cell 2008
Sendurai A Mani, Wenjun Guo, Mai-Jing Liao, Elinor Ng Eaton, Ayyakkannu Ayyanan, Alicia Y Zhou, Mary Brooks, Ferenc Reinhard, Cheng Cheng Zhang, Michail Shipitsin,[...]. Cell 2008
15
Identification of human brain tumour initiating cells.
Sheila K Singh, Cynthia Hawkins, Ian D Clarke, Jeremy A Squire, Jane Bayani, Takuichiro Hide, R Mark Henkelman, Michael D Cusimano, Peter B Dirks. Nature 2004
Sheila K Singh, Cynthia Hawkins, Ian D Clarke, Jeremy A Squire, Jane Bayani, Takuichiro Hide, R Mark Henkelman, Michael D Cusimano, Peter B Dirks. Nature 2004
13
Stem cells, cancer, and cancer stem cells.
T Reya, S J Morrison, M F Clarke, I L Weissman. Nature 2001
T Reya, S J Morrison, M F Clarke, I L Weissman. Nature 2001
13
Identification of a cancer stem cell in human brain tumors.
Sheila K Singh, Ian D Clarke, Mizuhiko Terasaki, Victoria E Bonn, Cynthia Hawkins, Jeremy Squire, Peter B Dirks. Cancer Res 2003
Sheila K Singh, Ian D Clarke, Mizuhiko Terasaki, Victoria E Bonn, Cynthia Hawkins, Jeremy Squire, Peter B Dirks. Cancer Res 2003
13
A human colon cancer cell capable of initiating tumour growth in immunodeficient mice.
Catherine A O'Brien, Aaron Pollett, Steven Gallinger, John E Dick. Nature 2007
Catherine A O'Brien, Aaron Pollett, Steven Gallinger, John E Dick. Nature 2007
12
ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome.
Christophe Ginestier, Min Hee Hur, Emmanuelle Charafe-Jauffret, Florence Monville, Julie Dutcher, Marty Brown, Jocelyne Jacquemier, Patrice Viens, Celina G Kleer, Suling Liu,[...]. Cell Stem Cell 2007
Christophe Ginestier, Min Hee Hur, Emmanuelle Charafe-Jauffret, Florence Monville, Julie Dutcher, Marty Brown, Jocelyne Jacquemier, Patrice Viens, Celina G Kleer, Suling Liu,[...]. Cell Stem Cell 2007
12
BCL-2 inhibition targets oxidative phosphorylation and selectively eradicates quiescent human leukemia stem cells.
Eleni D Lagadinou, Alexander Sach, Kevin Callahan, Randall M Rossi, Sarah J Neering, Mohammad Minhajuddin, John M Ashton, Shanshan Pei, Valerie Grose, Kristen M O'Dwyer,[...]. Cell Stem Cell 2013
Eleni D Lagadinou, Alexander Sach, Kevin Callahan, Randall M Rossi, Sarah J Neering, Mohammad Minhajuddin, John M Ashton, Shanshan Pei, Valerie Grose, Kristen M O'Dwyer,[...]. Cell Stem Cell 2013
11
Prospective identification of tumorigenic prostate cancer stem cells.
Anne T Collins, Paul A Berry, Catherine Hyde, Michael J Stower, Norman J Maitland. Cancer Res 2005
Anne T Collins, Paul A Berry, Catherine Hyde, Michael J Stower, Norman J Maitland. Cancer Res 2005
11
Identification of pancreatic cancer stem cells.
Chenwei Li, David G Heidt, Piero Dalerba, Charles F Burant, Lanjing Zhang, Volkan Adsay, Max Wicha, Michael F Clarke, Diane M Simeone. Cancer Res 2007
Chenwei Li, David G Heidt, Piero Dalerba, Charles F Burant, Lanjing Zhang, Volkan Adsay, Max Wicha, Michael F Clarke, Diane M Simeone. Cancer Res 2007
11
Identification and expansion of the tumorigenic lung cancer stem cell population.
A Eramo, F Lotti, G Sette, E Pilozzi, M Biffoni, A Di Virgilio, C Conticello, L Ruco, C Peschle, R De Maria. Cell Death Differ 2008
A Eramo, F Lotti, G Sette, E Pilozzi, M Biffoni, A Di Virgilio, C Conticello, L Ruco, C Peschle, R De Maria. Cell Death Differ 2008
10
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors.
Kazutoshi Takahashi, Shinya Yamanaka. Cell 2006
Kazutoshi Takahashi, Shinya Yamanaka. Cell 2006
9
Efficient tumour formation by single human melanoma cells.
Elsa Quintana, Mark Shackleton, Michael S Sabel, Douglas R Fullen, Timothy M Johnson, Sean J Morrison. Nature 2008
Elsa Quintana, Mark Shackleton, Michael S Sabel, Douglas R Fullen, Timothy M Johnson, Sean J Morrison. Nature 2008
9
Phenotypic characterization of human colorectal cancer stem cells.
Piero Dalerba, Scott J Dylla, In-Kyung Park, Rui Liu, Xinhao Wang, Robert W Cho, Timothy Hoey, Austin Gurney, Emina H Huang, Diane M Simeone,[...]. Proc Natl Acad Sci U S A 2007
Piero Dalerba, Scott J Dylla, In-Kyung Park, Rui Liu, Xinhao Wang, Robert W Cho, Timothy Hoey, Austin Gurney, Emina H Huang, Diane M Simeone,[...]. Proc Natl Acad Sci U S A 2007
9
9
A 17-gene stemness score for rapid determination of risk in acute leukaemia.
Stanley W K Ng, Amanda Mitchell, James A Kennedy, Weihsu C Chen, Jessica McLeod, Narmin Ibrahimova, Andrea Arruda, Andreea Popescu, Vikas Gupta, Aaron D Schimmer,[...]. Nature 2016
Stanley W K Ng, Amanda Mitchell, James A Kennedy, Weihsu C Chen, Jessica McLeod, Narmin Ibrahimova, Andrea Arruda, Andreea Popescu, Vikas Gupta, Aaron D Schimmer,[...]. Nature 2016
9
Stem cell gene expression programs influence clinical outcome in human leukemia.
Kolja Eppert, Katsuto Takenaka, Eric R Lechman, Levi Waldron, Björn Nilsson, Peter van Galen, Klaus H Metzeler, Armando Poeppl, Vicki Ling, Joseph Beyene,[...]. Nat Med 2011
Kolja Eppert, Katsuto Takenaka, Eric R Lechman, Levi Waldron, Björn Nilsson, Peter van Galen, Klaus H Metzeler, Armando Poeppl, Vicki Ling, Joseph Beyene,[...]. Nat Med 2011
8
Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity.
Kristin J Hope, Liqing Jin, John E Dick. Nat Immunol 2004
Kristin J Hope, Liqing Jin, John E Dick. Nat Immunol 2004
8
Biology and relevance of human acute myeloid leukemia stem cells.
Daniel Thomas, Ravindra Majeti. Blood 2017
Daniel Thomas, Ravindra Majeti. Blood 2017
8
The cancer stem cell niche: how essential is the niche in regulating stemness of tumor cells?
Vicki Plaks, Niwen Kong, Zena Werb. Cell Stem Cell 2015
Vicki Plaks, Niwen Kong, Zena Werb. Cell Stem Cell 2015
8
The interleukin-3 receptor alpha chain is a unique marker for human acute myelogenous leukemia stem cells.
C T Jordan, D Upchurch, S J Szilvassy, M L Guzman, D S Howard, A L Pettigrew, T Meyerrose, R Rossi, B Grimes, D A Rizzieri,[...]. Leukemia 2000
C T Jordan, D Upchurch, S J Szilvassy, M L Guzman, D S Howard, A L Pettigrew, T Meyerrose, R Rossi, B Grimes, D A Rizzieri,[...]. Leukemia 2000
8
Therapeutic targeting of acute myeloid leukemia stem cells.
Daniel A Pollyea, Craig T Jordan. Blood 2017
Daniel A Pollyea, Craig T Jordan. Blood 2017
8
Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma.
M E Prince, R Sivanandan, A Kaczorowski, G T Wolf, M J Kaplan, P Dalerba, I L Weissman, M F Clarke, L E Ailles. Proc Natl Acad Sci U S A 2007
M E Prince, R Sivanandan, A Kaczorowski, G T Wolf, M J Kaplan, P Dalerba, I L Weissman, M F Clarke, L E Ailles. Proc Natl Acad Sci U S A 2007
7
Identification of cells initiating human melanomas.
Tobias Schatton, George F Murphy, Natasha Y Frank, Kazuhiro Yamaura, Ana Maria Waaga-Gasser, Martin Gasser, Qian Zhan, Stefan Jordan, Lyn M Duncan, Carsten Weishaupt,[...]. Nature 2008
Tobias Schatton, George F Murphy, Natasha Y Frank, Kazuhiro Yamaura, Ana Maria Waaga-Gasser, Martin Gasser, Qian Zhan, Stefan Jordan, Lyn M Duncan, Carsten Weishaupt,[...]. Nature 2008
7
Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region.
Fumihiko Ishikawa, Shuro Yoshida, Yoriko Saito, Atsushi Hijikata, Hiroshi Kitamura, Satoshi Tanaka, Ryu Nakamura, Toru Tanaka, Hiroko Tomiyama, Noriyuki Saito,[...]. Nat Biotechnol 2007
Fumihiko Ishikawa, Shuro Yoshida, Yoriko Saito, Atsushi Hijikata, Hiroshi Kitamura, Satoshi Tanaka, Ryu Nakamura, Toru Tanaka, Hiroko Tomiyama, Noriyuki Saito,[...]. Nat Biotechnol 2007
7
Identification of therapeutic targets for quiescent, chemotherapy-resistant human leukemia stem cells.
Yoriko Saito, Hiroshi Kitamura, Atsushi Hijikata, Mariko Tomizawa-Murasawa, Satoshi Tanaka, Shinsuke Takagi, Naoyuki Uchida, Nahoko Suzuki, Akiko Sone, Yuho Najima,[...]. Sci Transl Med 2010
Yoriko Saito, Hiroshi Kitamura, Atsushi Hijikata, Mariko Tomizawa-Murasawa, Satoshi Tanaka, Shinsuke Takagi, Naoyuki Uchida, Nahoko Suzuki, Akiko Sone, Yuho Najima,[...]. Sci Transl Med 2010
7
Tracing the origins of relapse in acute myeloid leukaemia to stem cells.
Liran I Shlush, Amanda Mitchell, Lawrence Heisler, Sagi Abelson, Stanley W K Ng, Aaron Trotman-Grant, Jessie J F Medeiros, Abilasha Rao-Bhatia, Ivana Jaciw-Zurakowsky, Rene Marke,[...]. Nature 2017
Liran I Shlush, Amanda Mitchell, Lawrence Heisler, Sagi Abelson, Stanley W K Ng, Aaron Trotman-Grant, Jessie J F Medeiros, Abilasha Rao-Bhatia, Ivana Jaciw-Zurakowsky, Rene Marke,[...]. Nature 2017
7
Coexpression profile of leukemic stem cell markers for combinatorial targeted therapy in AML.
S Haubner, F Perna, T Köhnke, C Schmidt, S Berman, C Augsberger, F M Schnorfeil, C Krupka, F S Lichtenegger, X Liu,[...]. Leukemia 2019
S Haubner, F Perna, T Köhnke, C Schmidt, S Berman, C Augsberger, F M Schnorfeil, C Krupka, F S Lichtenegger, X Liu,[...]. Leukemia 2019
7
CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells.
Ravindra Majeti, Mark P Chao, Ash A Alizadeh, Wendy W Pang, Siddhartha Jaiswal, Kenneth D Gibbs, Nico van Rooijen, Irving L Weissman. Cell 2009
Ravindra Majeti, Mark P Chao, Ash A Alizadeh, Wendy W Pang, Siddhartha Jaiswal, Kenneth D Gibbs, Nico van Rooijen, Irving L Weissman. Cell 2009
7
Functional heterogeneity of genetically defined subclones in acute myeloid leukemia.
Jeffery M Klco, David H Spencer, Christopher A Miller, Malachi Griffith, Tamara L Lamprecht, Michelle O'Laughlin, Catrina Fronick, Vincent Magrini, Ryan T Demeter, Robert S Fulton,[...]. Cancer Cell 2014
Jeffery M Klco, David H Spencer, Christopher A Miller, Malachi Griffith, Tamara L Lamprecht, Michelle O'Laughlin, Catrina Fronick, Vincent Magrini, Ryan T Demeter, Robert S Fulton,[...]. Cancer Cell 2014
6
Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state.
Christine L Chaffer, Ines Brueckmann, Christina Scheel, Alicia J Kaestli, Paul A Wiggins, Leonardo O Rodrigues, Mary Brooks, Ferenc Reinhardt, Ying Su, Kornelia Polyak,[...]. Proc Natl Acad Sci U S A 2011
Christine L Chaffer, Ines Brueckmann, Christina Scheel, Alicia J Kaestli, Paul A Wiggins, Leonardo O Rodrigues, Mary Brooks, Ferenc Reinhardt, Ying Su, Kornelia Polyak,[...]. Proc Natl Acad Sci U S A 2011
6
6
Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer.
Patrick C Hermann, Stephan L Huber, Tanja Herrler, Alexandra Aicher, Joachim W Ellwart, Markus Guba, Christiane J Bruns, Christopher Heeschen. Cell Stem Cell 2007
Patrick C Hermann, Stephan L Huber, Tanja Herrler, Alexandra Aicher, Joachim W Ellwart, Markus Guba, Christiane J Bruns, Christopher Heeschen. Cell Stem Cell 2007
6
Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia.
Timothy J Ley, Christopher Miller, Li Ding, Benjamin J Raphael, Andrew J Mungall, A Gordon Robertson, Katherine Hoadley, Timothy J Triche, Peter W Laird, Jack D Baty,[...]. N Engl J Med 2013
Timothy J Ley, Christopher Miller, Li Ding, Benjamin J Raphael, Andrew J Mungall, A Gordon Robertson, Katherine Hoadley, Timothy J Triche, Peter W Laird, Jack D Baty,[...]. N Engl J Med 2013
6
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response.
Shideng Bao, Qiulian Wu, Roger E McLendon, Yueling Hao, Qing Shi, Anita B Hjelmeland, Mark W Dewhirst, Darell D Bigner, Jeremy N Rich. Nature 2006
Shideng Bao, Qiulian Wu, Roger E McLendon, Yueling Hao, Qing Shi, Anita B Hjelmeland, Mark W Dewhirst, Darell D Bigner, Jeremy N Rich. Nature 2006
6
Cancer stem cells in solid tumours: accumulating evidence and unresolved questions.
Jane E Visvader, Geoffrey J Lindeman. Nat Rev Cancer 2008
Jane E Visvader, Geoffrey J Lindeman. Nat Rev Cancer 2008
6
Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells.
Michael F Clarke, John E Dick, Peter B Dirks, Connie J Eaves, Catriona H M Jamieson, D Leanne Jones, Jane Visvader, Irving L Weissman, Geoffrey M Wahl. Cancer Res 2006
Michael F Clarke, John E Dick, Peter B Dirks, Connie J Eaves, Catriona H M Jamieson, D Leanne Jones, Jane Visvader, Irving L Weissman, Geoffrey M Wahl. Cancer Res 2006
6
Targeting cancer stem cell pathways for cancer therapy.
Liqun Yang, Pengfei Shi, Gaichao Zhao, Jie Xu, Wen Peng, Jiayi Zhang, Guanghui Zhang, Xiaowen Wang, Zhen Dong, Fei Chen,[...]. Signal Transduct Target Ther 2020
Liqun Yang, Pengfei Shi, Gaichao Zhao, Jie Xu, Wen Peng, Jiayi Zhang, Guanghui Zhang, Xiaowen Wang, Zhen Dong, Fei Chen,[...]. Signal Transduct Target Ther 2020
6
Linking EMT programmes to normal and neoplastic epithelial stem cells.
Arthur W Lambert, Robert A Weinberg. Nat Rev Cancer 2021
Arthur W Lambert, Robert A Weinberg. Nat Rev Cancer 2021
8
Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing.
Li Ding, Timothy J Ley, David E Larson, Christopher A Miller, Daniel C Koboldt, John S Welch, Julie K Ritchey, Margaret A Young, Tamara Lamprecht, Michael D McLellan,[...]. Nature 2012
Li Ding, Timothy J Ley, David E Larson, Christopher A Miller, Daniel C Koboldt, John S Welch, Julie K Ritchey, Margaret A Young, Tamara Lamprecht, Michael D McLellan,[...]. Nature 2012
5
A restricted cell population propagates glioblastoma growth after chemotherapy.
Jian Chen, Yanjiao Li, Tzong-Shiue Yu, Renée M McKay, Dennis K Burns, Steven G Kernie, Luis F Parada. Nature 2012
Jian Chen, Yanjiao Li, Tzong-Shiue Yu, Renée M McKay, Dennis K Burns, Steven G Kernie, Luis F Parada. Nature 2012
5
Single-Cell RNA-Seq Reveals AML Hierarchies Relevant to Disease Progression and Immunity.
Peter van Galen, Volker Hovestadt, Marc H Wadsworth Ii, Travis K Hughes, Gabriel K Griffin, Sofia Battaglia, Julia A Verga, Jason Stephansky, Timothy J Pastika, Jennifer Lombardi Story,[...]. Cell 2019
Peter van Galen, Volker Hovestadt, Marc H Wadsworth Ii, Travis K Hughes, Gabriel K Griffin, Sofia Battaglia, Julia A Verga, Jason Stephansky, Timothy J Pastika, Jennifer Lombardi Story,[...]. Cell 2019
5
Heterogeneity in cancer: cancer stem cells versus clonal evolution.
Mark Shackleton, Elsa Quintana, Eric R Fearon, Sean J Morrison. Cell 2009
Mark Shackleton, Elsa Quintana, Eric R Fearon, Sean J Morrison. Cell 2009
5
Genomic Classification and Prognosis in Acute Myeloid Leukemia.
Elli Papaemmanuil, Moritz Gerstung, Lars Bullinger, Verena I Gaidzik, Peter Paschka, Nicola D Roberts, Nicola E Potter, Michael Heuser, Felicitas Thol, Niccolo Bolli,[...]. N Engl J Med 2016
Elli Papaemmanuil, Moritz Gerstung, Lars Bullinger, Verena I Gaidzik, Peter Paschka, Nicola D Roberts, Nicola E Potter, Michael Heuser, Felicitas Thol, Niccolo Bolli,[...]. N Engl J Med 2016
5
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.