N Suzuki, A Shimamoto, O Imamura, J Kuromitsu, S Kitao, M Goto, Y Furuichi. Nucleic Acids Res 1997
Times Cited: 189
Times Cited: 189
Times Cited
Times Co-cited
Similarity
Positional cloning of the Werner's syndrome gene.
C E Yu, J Oshima, Y H Fu, E M Wijsman, F Hisama, R Alisch, S Matthews, J Nakura, T Miki, S Ouais,[...]. Science 1996
C E Yu, J Oshima, Y H Fu, E M Wijsman, F Hisama, R Alisch, S Matthews, J Nakura, T Miki, S Ouais,[...]. Science 1996
76
The Werner syndrome protein is a DNA helicase.
M D Gray, J C Shen, A S Kamath-Loeb, A Blank, B L Sopher, G M Martin, J Oshima, L A Loeb. Nat Genet 1997
M D Gray, J C Shen, A S Kamath-Loeb, A Blank, B L Sopher, G M Martin, J Oshima, L A Loeb. Nat Genet 1997
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The premature ageing syndrome protein, WRN, is a 3'-->5' exonuclease.
S Huang, B Li, M D Gray, J Oshima, I S Mian, J Campisi. Nat Genet 1998
S Huang, B Li, M D Gray, J Oshima, I S Mian, J Campisi. Nat Genet 1998
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Werner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest.
A Constantinou, M Tarsounas, J K Karow, R M Brosh, V A Bohr, I D Hickson, S C West. EMBO Rep 2000
A Constantinou, M Tarsounas, J K Karow, R M Brosh, V A Bohr, I D Hickson, S C West. EMBO Rep 2000
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Ku complex interacts with and stimulates the Werner protein.
M P Cooper, A Machwe, D K Orren, R M Brosh, D Ramsden, V A Bohr. Genes Dev 2000
M P Cooper, A Machwe, D K Orren, R M Brosh, D Ramsden, V A Bohr. Genes Dev 2000
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Characterization of Werner syndrome protein DNA helicase activity: directionality, substrate dependence and stimulation by replication protein A.
J C Shen, M D Gray, J Oshima, L A Loeb. Nucleic Acids Res 1998
J C Shen, M D Gray, J Oshima, L A Loeb. Nucleic Acids Res 1998
42
The Werner syndrome gene product co-purifies with the DNA replication complex and interacts with PCNA and topoisomerase I.
M Lebel, E A Spillare, C C Harris, P Leder. J Biol Chem 1999
M Lebel, E A Spillare, C C Harris, P Leder. J Biol Chem 1999
39
Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity.
R M Brosh, C von Kobbe, J A Sommers, P Karmakar, P L Opresko, J Piotrowski, I Dianova, G L Dianov, V A Bohr. EMBO J 2001
R M Brosh, C von Kobbe, J A Sommers, P Karmakar, P L Opresko, J Piotrowski, I Dianova, G L Dianov, V A Bohr. EMBO J 2001
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Werner syndrome protein. I. DNA helicase and dna exonuclease reside on the same polypeptide.
J C Shen, M D Gray, J Oshima, A S Kamath-Loeb, M Fry, L A Loeb. J Biol Chem 1998
J C Shen, M D Gray, J Oshima, A S Kamath-Loeb, M Fry, L A Loeb. J Biol Chem 1998
36
The Bloom's syndrome gene product is homologous to RecQ helicases.
N A Ellis, J Groden, T Z Ye, J Straughen, D J Lennon, S Ciocci, M Proytcheva, J German. Cell 1995
N A Ellis, J Groden, T Z Ye, J Straughen, D J Lennon, S Ciocci, M Proytcheva, J German. Cell 1995
36
Werner's syndrome a review of its symptomatology, natural history, pathologic features, genetics and relationship to the natural aging process.
C J Epstein, G M Martin, A L Schultz, A G Motulsky. Medicine (Baltimore) 1966
C J Epstein, G M Martin, A L Schultz, A G Motulsky. Medicine (Baltimore) 1966
36
Functional and physical interaction between WRN helicase and human replication protein A.
R M Brosh, D K Orren, J O Nehlin, P H Ravn, M K Kenny, A Machwe, V A Bohr. J Biol Chem 1999
R M Brosh, D K Orren, J O Nehlin, P H Ravn, M K Kenny, A Machwe, V A Bohr. J Biol Chem 1999
35
Werner syndrome protein. II. Characterization of the integral 3' --> 5' DNA exonuclease.
A S Kamath-Loeb, J C Shen, L A Loeb, M Fry. J Biol Chem 1998
A S Kamath-Loeb, J C Shen, L A Loeb, M Fry. J Biol Chem 1998
32
Mutator phenotype of Werner syndrome is characterized by extensive deletions.
K Fukuchi, G M Martin, R J Monnat. Proc Natl Acad Sci U S A 1989
K Fukuchi, G M Martin, R J Monnat. Proc Natl Acad Sci U S A 1989
32
The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases.
P Mohaghegh, J K Karow, R M Brosh, V A Bohr, I D Hickson. Nucleic Acids Res 2001
P Mohaghegh, J K Karow, R M Brosh, V A Bohr, I D Hickson. Nucleic Acids Res 2001
31
Functional interaction between the Werner Syndrome protein and DNA polymerase delta.
A S Kamath-Loeb, E Johansson, P M Burgers, L A Loeb. Proc Natl Acad Sci U S A 2000
A S Kamath-Loeb, E Johansson, P M Burgers, L A Loeb. Proc Natl Acad Sci U S A 2000
30
An apoptosis-inducing genotoxin differentiates heterozygotic carriers for Werner helicase mutations from wild-type and homozygous mutants.
C E Ogburn, J Oshima, M Poot, R Chen, K E Hunt, K A Gollahon, P S Rabinovitch, G M Martin. Hum Genet 1997
C E Ogburn, J Oshima, M Poot, R Chen, K E Hunt, K A Gollahon, P S Rabinovitch, G M Martin. Hum Genet 1997
30
Impaired S-phase transit of Werner syndrome cells expressed in lymphoblastoid cell lines.
M Poot, H Hoehn, T M Rünger, G M Martin. Exp Cell Res 1992
M Poot, H Hoehn, T M Rünger, G M Martin. Exp Cell Res 1992
30
Human werner syndrome DNA helicase unwinds tetrahelical structures of the fragile X syndrome repeat sequence d(CGG)n.
M Fry, L A Loeb. J Biol Chem 1999
M Fry, L A Loeb. J Biol Chem 1999
29
Functional interaction between Ku and the werner syndrome protein in DNA end processing.
B Li, L Comai. J Biol Chem 2000
B Li, L Comai. J Biol Chem 2000
29
A deletion within the murine Werner syndrome helicase induces sensitivity to inhibitors of topoisomerase and loss of cellular proliferative capacity.
M Lebel, P Leder. Proc Natl Acad Sci U S A 1998
M Lebel, P Leder. Proc Natl Acad Sci U S A 1998
28
Werner syndrome helicase contains a 5'-->3' exonuclease activity that digests DNA and RNA strands in DNA/DNA and RNA/DNA duplexes dependent on unwinding.
N Suzuki, M Shiratori, M Goto, Y Furuichi. Nucleic Acids Res 1999
N Suzuki, M Shiratori, M Goto, Y Furuichi. Nucleic Acids Res 1999
30
Mutations in RECQL4 cause a subset of cases of Rothmund-Thomson syndrome.
S Kitao, A Shimamoto, M Goto, R W Miller, W A Smithson, N M Lindor, Y Furuichi. Nat Genet 1999
S Kitao, A Shimamoto, M Goto, R W Miller, W A Smithson, N M Lindor, Y Furuichi. Nat Genet 1999
25
Werner syndrome lymphoblastoid cells are sensitive to camptothecin-induced apoptosis in S-phase.
M Poot, K A Gollahon, P S Rabinovitch. Hum Genet 1999
M Poot, K A Gollahon, P S Rabinovitch. Hum Genet 1999
25
Werner syndrome cells are sensitive to DNA cross-linking drugs.
M Poot, J S Yom, S H Whang, J T Kato, K A Gollahon, P S Rabinovitch. FASEB J 2001
M Poot, J S Yom, S H Whang, J T Kato, K A Gollahon, P S Rabinovitch. FASEB J 2001
25
Cytogenetics of Werner's syndrome cultured skin fibroblasts: variegated translocation mosaicism.
D Salk, K Au, H Hoehn, G M Martin. Cytogenet Cell Genet 1981
D Salk, K Au, H Hoehn, G M Martin. Cytogenet Cell Genet 1981
24
p53-mediated apoptosis is attenuated in Werner syndrome cells.
E A Spillare, A I Robles, X W Wang, J C Shen, C E Yu, G D Schellenberg, C C Harris. Genes Dev 1999
E A Spillare, A I Robles, X W Wang, J C Shen, C E Yu, G D Schellenberg, C C Harris. Genes Dev 1999
23
Werner syndrome exonuclease catalyzes structure-dependent degradation of DNA.
J C Shen, L A Loeb. Nucleic Acids Res 2000
J C Shen, L A Loeb. Nucleic Acids Res 2000
29
Telomere-binding protein TRF2 binds to and stimulates the Werner and Bloom syndrome helicases.
Patricia L Opresko, Cayetano von Kobbe, Jean-Philippe Laine, Jeanine Harrigan, Ian D Hickson, Vilhelm A Bohr. J Biol Chem 2002
Patricia L Opresko, Cayetano von Kobbe, Jean-Philippe Laine, Jeanine Harrigan, Ian D Hickson, Vilhelm A Bohr. J Biol Chem 2002
23
The Bloom's syndrome gene product is a 3'-5' DNA helicase.
J K Karow, R K Chakraverty, I D Hickson. J Biol Chem 1997
J K Karow, R K Chakraverty, I D Hickson. J Biol Chem 1997
22
Characterization of the human and mouse WRN 3'-->5' exonuclease.
S Huang, S Beresten, B Li, J Oshima, N A Ellis, J Campisi. Nucleic Acids Res 2000
S Huang, S Beresten, B Li, J Oshima, N A Ellis, J Campisi. Nucleic Acids Res 2000
22
Physical and functional interaction between p53 and the Werner's syndrome protein.
G Blander, J Kipnis, J F Leal, C E Yu, G D Schellenberg, M Oren. J Biol Chem 1999
G Blander, J Kipnis, J F Leal, C E Yu, G D Schellenberg, M Oren. J Biol Chem 1999
22
A functional interaction of Ku with Werner exonuclease facilitates digestion of damaged DNA.
D K Orren, A Machwe, P Karmakar, J Piotrowski, M P Cooper, V A Bohr. Nucleic Acids Res 2001
D K Orren, A Machwe, P Karmakar, J Piotrowski, M P Cooper, V A Bohr. Nucleic Acids Res 2001
28
Excess of rare cancers in Werner syndrome (adult progeria).
M Goto, R W Miller, Y Ishikawa, H Sugano. Cancer Epidemiol Biomarkers Prev 1996
M Goto, R W Miller, Y Ishikawa, H Sugano. Cancer Epidemiol Biomarkers Prev 1996
22
Telomerase prevents the accelerated cell ageing of Werner syndrome fibroblasts.
F S Wyllie, C J Jones, J W Skinner, M F Haughton, C Wallis, D Wynford-Thomas, R G Faragher, D Kipling. Nat Genet 2000
F S Wyllie, C J Jones, J W Skinner, M F Haughton, C Wallis, D Wynford-Thomas, R G Faragher, D Kipling. Nat Genet 2000
21
Replication focus-forming activity 1 and the Werner syndrome gene product.
H Yan, C Y Chen, R Kobayashi, J Newport. Nat Genet 1998
H Yan, C Y Chen, R Kobayashi, J Newport. Nat Genet 1998
21
Replication protein A physically interacts with the Bloom's syndrome protein and stimulates its helicase activity.
R M Brosh, J L Li, M K Kenny, J K Karow, M P Cooper, R P Kureekattil, I D Hickson, V A Bohr. J Biol Chem 2000
R M Brosh, J L Li, M K Kenny, J K Karow, M P Cooper, R P Kureekattil, I D Hickson, V A Bohr. J Biol Chem 2000
21
The Bloom's syndrome helicase unwinds G4 DNA.
H Sun, J K Karow, I D Hickson, N Maizels. J Biol Chem 1998
H Sun, J K Karow, I D Hickson, N Maizels. J Biol Chem 1998
21
Unwinding of a DNA triple helix by the Werner and Bloom syndrome helicases.
R M Brosh, A Majumdar, S Desai, I D Hickson, V A Bohr, M M Seidman. J Biol Chem 2001
R M Brosh, A Majumdar, S Desai, I D Hickson, V A Bohr, M M Seidman. J Biol Chem 2001
21
p53 Modulates the exonuclease activity of Werner syndrome protein.
R M Brosh, P Karmakar, J A Sommers, Q Yang, X W Wang, E A Spillare, C C Harris, V A Bohr. J Biol Chem 2001
R M Brosh, P Karmakar, J A Sommers, Q Yang, X W Wang, E A Spillare, C C Harris, V A Bohr. J Biol Chem 2001
25
The yeast type I topoisomerase Top3 interacts with Sgs1, a DNA helicase homolog: a potential eukaryotic reverse gyrase.
S Gangloff, J P McDonald, C Bendixen, L Arthur, R Rothstein. Mol Cell Biol 1994
S Gangloff, J P McDonald, C Bendixen, L Arthur, R Rothstein. Mol Cell Biol 1994
20
Accelerated loss of telomeric repeats may not explain accelerated replicative decline of Werner syndrome cells.
V P Schulz, V A Zakian, C E Ogburn, J McKay, A A Jarzebowicz, S D Edland, G M Martin. Hum Genet 1996
V P Schulz, V A Zakian, C E Ogburn, J McKay, A A Jarzebowicz, S D Edland, G M Martin. Hum Genet 1996
20
Bloom's and Werner's syndrome genes suppress hyperrecombination in yeast sgs1 mutant: implication for genomic instability in human diseases.
K Yamagata, J Kato, A Shimamoto, M Goto, Y Furuichi, H Ikeda. Proc Natl Acad Sci U S A 1998
K Yamagata, J Kato, A Shimamoto, M Goto, Y Furuichi, H Ikeda. Proc Natl Acad Sci U S A 1998
20
Requirements for the nucleolytic processing of DNA ends by the Werner syndrome protein-Ku70/80 complex.
B Li, L Comai. J Biol Chem 2001
B Li, L Comai. J Biol Chem 2001
22
Interactions between the Werner syndrome helicase and DNA polymerase delta specifically facilitate copying of tetraplex and hairpin structures of the d(CGG)n trinucleotide repeat sequence.
A S Kamath-Loeb, L A Loeb, E Johansson, P M Burgers, M Fry. J Biol Chem 2001
A S Kamath-Loeb, L A Loeb, E Johansson, P M Burgers, M Fry. J Biol Chem 2001
20
Werner syndrome protein is regulated and phosphorylated by DNA-dependent protein kinase.
S M Yannone, S Roy, D W Chan, M B Murphy, S Huang, J Campisi, D J Chen. J Biol Chem 2001
S M Yannone, S Roy, D W Chan, M B Murphy, S Huang, J Campisi, D J Chen. J Biol Chem 2001
20
Impaired nuclear localization of defective DNA helicases in Werner's syndrome.
T Matsumoto, A Shimamoto, M Goto, Y Furuichi. Nat Genet 1997
T Matsumoto, A Shimamoto, M Goto, Y Furuichi. Nat Genet 1997
20
Werner's syndrome protein is required for correct recovery after replication arrest and DNA damage induced in S-phase of cell cycle.
P Pichierri, A Franchitto, P Mosesso, F Palitti. Mol Biol Cell 2001
P Pichierri, A Franchitto, P Mosesso, F Palitti. Mol Biol Cell 2001
19
The Bloom's syndrome gene product promotes branch migration of holliday junctions.
J K Karow, A Constantinou, J L Li, S C West, I D Hickson. Proc Natl Acad Sci U S A 2000
J K Karow, A Constantinou, J L Li, S C West, I D Hickson. Proc Natl Acad Sci U S A 2000
18
The Werner syndrome protein is involved in RNA polymerase II transcription.
A S Balajee, A Machwe, A May, M D Gray, J Oshima, G M Martin, J O Nehlin, R Brosh, D K Orren, V A Bohr. Mol Biol Cell 1999
A S Balajee, A Machwe, A May, M D Gray, J Oshima, G M Martin, J O Nehlin, R Brosh, D K Orren, V A Bohr. Mol Biol Cell 1999
18
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.