A citation-based method for searching scientific literature

T M Nakamura, G B Morin, K B Chapman, S L Weinrich, W H Andrews, J Lingner, C B Harley, T R Cech. Science 1997
Times Cited: 1932







List of co-cited articles
887 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


The RNA component of human telomerase.
J Feng, W D Funk, S S Wang, S L Weinrich, A A Avilion, C P Chiu, R R Adams, E Chang, R C Allsopp, J Yu. Science 1995
31

Specific association of human telomerase activity with immortal cells and cancer.
N W Kim, M A Piatyszek, K R Prowse, C B Harley, M D West, P L Ho, G M Coviello, W E Wright, S L Weinrich, J W Shay. Science 1994
28

A survey of telomerase activity in human cancer.
J W Shay, S Bacchetti. Eur J Cancer 1997
28

hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization.
M Meyerson, C M Counter, E N Eaton, L W Ellisen, P Steiner, S D Caddle, L Ziaugra, R L Beijersbergen, M J Davidoff, Q Liu,[...]. Cell 1997
22



Telomeres shorten during ageing of human fibroblasts.
C B Harley, A B Futcher, C W Greider. Nature 1990
17

TERT promoter mutations in familial and sporadic melanoma.
Susanne Horn, Adina Figl, P Sivaramakrishna Rachakonda, Christine Fischer, Antje Sucker, Andreas Gast, Stephanie Kadel, Iris Moll, Eduardo Nagore, Kari Hemminki,[...]. Science 2013
16

Highly recurrent TERT promoter mutations in human melanoma.
Franklin W Huang, Eran Hodis, Mary Jue Xu, Gregory V Kryukov, Lynda Chin, Levi A Garraway. Science 2013
15

Reverse transcriptase motifs in the catalytic subunit of telomerase.
J Lingner, T R Hughes, A Shevchenko, M Mann, V Lundblad, T R Cech. Science 1997
973
14

Mammalian telomeres end in a large duplex loop.
J D Griffith, L Comeau, S Rosenfield, R M Stansel, A Bianchi, H Moss, T de Lange. Cell 1999
13

Systematic analysis of telomere length and somatic alterations in 31 cancer types.
Floris P Barthel, Wei Wei, Ming Tang, Emmanuel Martinez-Ledesma, Xin Hu, Samirkumar B Amin, Kadir C Akdemir, Sahil Seth, Xingzhi Song, Qianghu Wang,[...]. Nat Genet 2017
286
13

Extension of life-span by introduction of telomerase into normal human cells.
A G Bodnar, M Ouellette, M Frolkis, S E Holt, C P Chiu, G B Morin, C B Harley, J W Shay, S Lichtsteiner, W E Wright. Science 1998
13

Telomerase activity in human germline and embryonic tissues and cells.
W E Wright, M A Piatyszek, W E Rainey, W Byrd, J W Shay. Dev Genet 1996
977
12

Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT.
S L Weinrich, R Pruzan, L Ma, M Ouellette, V M Tesmer, S E Holt, A G Bodnar, S Lichtsteiner, N W Kim, J B Trager,[...]. Nat Genet 1997
799
11

Super-resolution fluorescence imaging of telomeres reveals TRF2-dependent T-loop formation.
Ylli Doksani, John Y Wu, Titia de Lange, Xiaowei Zhuang. Cell 2013
295
11

Cryo-EM structure of substrate-bound human telomerase holoenzyme.
Thi Hoang Duong Nguyen, Jane Tam, Robert A Wu, Basil J Greber, Daniel Toso, Eva Nogales, Kathleen Collins. Nature 2018
115
11


Telomerase Mechanism of Telomere Synthesis.
R Alex Wu, Heather E Upton, Jacob M Vogan, Kathleen Collins. Annu Rev Biochem 2017
110
11

Structure and function of telomeres.
E H Blackburn. Nature 1991
10


How shelterin protects mammalian telomeres.
Wilhelm Palm, Titia de Lange. Annu Rev Genet 2008
10

Telomerase activation by genomic rearrangements in high-risk neuroblastoma.
Martin Peifer, Falk Hertwig, Frederik Roels, Daniel Dreidax, Moritz Gartlgruber, Roopika Menon, Andrea Krämer, Justin L Roncaioli, Frederik Sand, Johannes M Heuckmann,[...]. Nature 2015
335
10

Mutation of the TERT promoter, switch to active chromatin, and monoallelic TERT expression in multiple cancers.
Josh Lewis Stern, Dan Theodorescu, Bert Vogelstein, Nickolas Papadopoulos, Thomas R Cech. Genes Dev 2015
127
10



Alternative lengthening of telomeres: models, mechanisms and implications.
Anthony J Cesare, Roger R Reddel. Nat Rev Genet 2010
617
9

Cancer. The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer.
Robert J A Bell, H Tomas Rube, Alex Kreig, Andrew Mancini, Shaun D Fouse, Raman P Nagarajan, Serah Choi, Chibo Hong, Daniel He, Melike Pekmezci,[...]. Science 2015
340
9

Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication.
Agnel Sfeir, Settapong T Kosiyatrakul, Dirk Hockemeyer, Sheila L MacRae, Jan Karlseder, Carl L Schildkraut, Titia de Lange. Cell 2009
682
9

DNA damage foci at dysfunctional telomeres.
Hiroyuki Takai, Agata Smogorzewska, Titia de Lange. Curr Biol 2003
9

Telomeres and telomerase: three decades of progress.
Jerry W Shay, Woodring E Wright. Nat Rev Genet 2019
280
9

Hallmarks of cancer: the next generation.
Douglas Hanahan, Robert A Weinberg. Cell 2011
8

The serial cultivation of human diploid cell strains.
L HAYFLICK, P S MOORHEAD. Exp Cell Res 1961
8

Cancer. TERT promoter mutations and telomerase reactivation in urothelial cancer.
Sumit Borah, Linghe Xi, Arthur J Zaug, Natasha M Powell, Garrett M Dancik, Scott B Cohen, James C Costello, Dan Theodorescu, Thomas R Cech. Science 2015
211
8

TPP1 is a homologue of ciliate TEBP-beta and interacts with POT1 to recruit telomerase.
Huawei Xin, Dan Liu, Ma Wan, Amin Safari, Hyeung Kim, Wen Sun, Matthew S O'Connor, Zhou Songyang. Nature 2007
370
8

A human telomerase holoenzyme protein required for Cajal body localization and telomere synthesis.
Andrew S Venteicher, Eladio B Abreu, Zhaojing Meng, Kelly E McCann, Rebecca M Terns, Timothy D Veenstra, Michael P Terns, Steven E Artandi. Science 2009
360
8

A DNA damage checkpoint response in telomere-initiated senescence.
Fabrizio d'Adda di Fagagna, Philip M Reaper, Lorena Clay-Farrace, Heike Fiegler, Philippa Carr, Thomas Von Zglinicki, Gabriele Saretzki, Nigel P Carter, Stephen P Jackson. Nature 2003
8

The telomere syndromes.
Mary Armanios, Elizabeth H Blackburn. Nat Rev Genet 2012
609
8

Shelterin-Mediated Telomere Protection.
Titia de Lange. Annu Rev Genet 2018
297
8

Structure of Telomerase with Telomeric DNA.
Jiansen Jiang, Yaqiang Wang, Lukas Sušac, Henry Chan, Ritwika Basu, Z Hong Zhou, Juli Feigon. Cell 2018
73
10



TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal.
Patrick J Killela, Zachary J Reitman, Yuchen Jiao, Chetan Bettegowda, Nishant Agrawal, Luis A Diaz, Allan H Friedman, Henry Friedman, Gary L Gallia, Beppino C Giovanella,[...]. Proc Natl Acad Sci U S A 2013
938
7

Telomerase mutations in families with idiopathic pulmonary fibrosis.
Mary Y Armanios, Julian J-L Chen, Joy D Cogan, Jonathan K Alder, Roxann G Ingersoll, Cheryl Markin, William E Lawson, Mingyi Xie, Irma Vulto, John A Phillips,[...]. N Engl J Med 2007
861
7

Frequency of TERT promoter mutations in human cancers.
João Vinagre, Ana Almeida, Helena Pópulo, Rui Batista, Joana Lyra, Vasco Pinto, Ricardo Coelho, Ricardo Celestino, Hugo Prazeres, Luis Lima,[...]. Nat Commun 2013
575
7

The POT1-TPP1 telomere complex is a telomerase processivity factor.
Feng Wang, Elaine R Podell, Arthur J Zaug, Yuting Yang, Paul Baciu, Thomas R Cech, Ming Lei. Nature 2007
488
7

The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity.
Jayakrishnan Nandakumar, Caitlin F Bell, Ina Weidenfeld, Arthur J Zaug, Leslie A Leinwand, Thomas R Cech. Nature 2012
224
7

Cancer-associated TERT promoter mutations abrogate telomerase silencing.
Kunitoshi Chiba, Joshua Z Johnson, Jacob M Vogan, Tina Wagner, John M Boyle, Dirk Hockemeyer. Elife 2015
170
7


Regulation of the Human Telomerase Gene TERT by Telomere Position Effect-Over Long Distances (TPE-OLD): Implications for Aging and Cancer.
Wanil Kim, Andrew T Ludlow, Jaewon Min, Jerome D Robin, Guido Stadler, Ilgen Mender, Tsung-Po Lai, Ning Zhang, Woodring E Wright, Jerry W Shay. PLoS Biol 2016
100
7


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.