A citation-based method for searching scientific literature

M G Spillantini, M L Schmidt, V M Lee, J Q Trojanowski, R Jakes, M Goedert. Nature 1997
Times Cited: 5531







List of co-cited articles
857 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Staging of brain pathology related to sporadic Parkinson's disease.
Heiko Braak, Kelly Del Tredici, Udo Rüb, Rob A I de Vos, Ernst N H Jansen Steur, Eva Braak. Neurobiol Aging 2003
26

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease.
M H Polymeropoulos, C Lavedan, E Leroy, S E Ide, A Dehejia, A Dutra, B Pike, H Root, J Rubenstein, R Boyer,[...]. Science 1997
23

Pathological α-synuclein transmission initiates Parkinson-like neurodegeneration in nontransgenic mice.
Kelvin C Luk, Victoria Kehm, Jenna Carroll, Bin Zhang, Patrick O'Brien, John Q Trojanowski, Virginia M-Y Lee. Science 2012
17

Lewy pathology in Parkinson's disease consists of crowded organelles and lipid membranes.
Sarah H Shahmoradian, Amanda J Lewis, Christel Genoud, Jürgen Hench, Tim E Moors, Paula P Navarro, Daniel Castaño-Díez, Gabriel Schweighauser, Alexandra Graff-Meyer, Kenneth N Goldie,[...]. Nat Neurosci 2019
355
15

Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro.
Jacqueline Burré, Manu Sharma, Theodoros Tsetsenis, Vladimir Buchman, Mark R Etherton, Thomas C Südhof. Science 2010
15

Exogenous α-synuclein fibrils induce Lewy body pathology leading to synaptic dysfunction and neuron death.
Laura A Volpicelli-Daley, Kelvin C Luk, Tapan P Patel, Selcuk A Tanik, Dawn M Riddle, Anna Stieber, David F Meaney, John Q Trojanowski, Virginia M-Y Lee. Neuron 2011
932
14

Parkinson's disease.
Lorraine V Kalia, Anthony E Lang. Lancet 2015
12

Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation.
Jia-Yi Li, Elisabet Englund, Janice L Holton, Denis Soulet, Peter Hagell, Andrew J Lees, Tammaryn Lashley, Niall P Quinn, Stig Rehncrona, Anders Björklund,[...]. Nat Med 2008
12

The process of Lewy body formation, rather than simply α-synuclein fibrillization, is one of the major drivers of neurodegeneration.
Anne-Laure Mahul-Mellier, Johannes Burtscher, Niran Maharjan, Laura Weerens, Marie Croisier, Fabien Kuttler, Marion Leleu, Graham W Knott, Hilal A Lashuel. Proc Natl Acad Sci U S A 2020
218
12

alpha-Synuclein locus triplication causes Parkinson's disease.
A B Singleton, M Farrer, J Johnson, A Singleton, S Hague, J Kachergus, M Hulihan, T Peuralinna, A Dutra, R Nussbaum,[...]. Science 2003
12

alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies.
M G Spillantini, R A Crowther, R Jakes, M Hasegawa, M Goedert. Proc Natl Acad Sci U S A 1998
11


Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease.
Jeffrey H Kordower, Yaping Chu, Robert A Hauser, Thomas B Freeman, C Warren Olanow. Nat Med 2008
10

Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies.
M Baba, S Nakajo, P H Tu, T Tomita, K Nakaya, V M Lee, J Q Trojanowski, T Iwatsubo. Am J Pathol 1998
9


alpha-Synuclein is phosphorylated in synucleinopathy lesions.
Hideo Fujiwara, Masato Hasegawa, Naoshi Dohmae, Akiko Kawashima, Eliezer Masliah, Matthew S Goldberg, Jie Shen, Koji Takio, Takeshi Iwatsubo. Nat Cell Biol 2002
9

Structural and functional characterization of two alpha-synuclein strains.
Luc Bousset, Laura Pieri, Gemma Ruiz-Arlandis, Julia Gath, Poul Henning Jensen, Birgit Habenstein, Karine Madiona, Vincent Olieric, Anja Böckmann, Beat H Meier,[...]. Nat Commun 2013
545
8

Aggregated alpha-synuclein activates microglia: a process leading to disease progression in Parkinson's disease.
Wei Zhang, Tongguang Wang, Zhong Pei, David S Miller, Xuefei Wu, Michelle L Block, Belinda Wilson, Wanqin Zhang, Yong Zhou, Jau-Shyong Hong,[...]. FASEB J 2005
866
8

Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomers.
Giuliana Fusco, Serene W Chen, Philip T F Williamson, Roberta Cascella, Michele Perni, James A Jarvis, Cristina Cecchi, Michele Vendruscolo, Fabrizio Chiti, Nunilo Cremades,[...]. Science 2017
312
8

Filamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies.
M G Spillantini, R A Crowther, R Jakes, N J Cairns, P L Lantos, M Goedert. Neurosci Lett 1998
746
8

Prion-like spreading of pathological α-synuclein in brain.
Masami Masuda-Suzukake, Takashi Nonaka, Masato Hosokawa, Takayuki Oikawa, Tetsuaki Arai, Haruhiko Akiyama, David M A Mann, Masato Hasegawa. Brain 2013
548
8

Transneuronal Propagation of Pathologic α-Synuclein from the Gut to the Brain Models Parkinson's Disease.
Sangjune Kim, Seung-Hwan Kwon, Tae-In Kam, Nikhil Panicker, Senthilkumar S Karuppagounder, Saebom Lee, Jun Hee Lee, Wonjoong Richard Kim, Minjee Kook, Catherine A Foss,[...]. Neuron 2019
506
8

In vivo demonstration that alpha-synuclein oligomers are toxic.
Beate Winner, Roberto Jappelli, Samir K Maji, Paula A Desplats, Leah Boyer, Stefan Aigner, Claudia Hetzer, Thomas Loher, Marçal Vilar, Silvia Campioni,[...]. Proc Natl Acad Sci U S A 2011
971
8


Exogenous alpha-synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells.
Kelvin C Luk, Cheng Song, Patrick O'Brien, Anna Stieber, Jonathan R Branch, Kurt R Brunden, John Q Trojanowski, Virginia M-Y Lee. Proc Natl Acad Sci U S A 2009
619
8

Parkinson's disease: mechanisms and models.
William Dauer, Serge Przedborski. Neuron 2003
7

MDS clinical diagnostic criteria for Parkinson's disease.
Ronald B Postuma, Daniela Berg, Matthew Stern, Werner Poewe, C Warren Olanow, Wolfgang Oertel, José Obeso, Kenneth Marek, Irene Litvan, Anthony E Lang,[...]. Mov Disord 2015
7

100 years of Lewy pathology.
Michel Goedert, Maria Grazia Spillantini, Kelly Del Tredici, Heiko Braak. Nat Rev Neurol 2013
675
7

The function of α-synuclein.
Jacob T Bendor, Todd P Logan, Robert H Edwards. Neuron 2013
462
7

Cell-produced alpha-synuclein is secreted in a calcium-dependent manner by exosomes and impacts neuronal survival.
Evangelia Emmanouilidou, Katerina Melachroinou, Theodoros Roumeliotis, Spiros D Garbis, Maria Ntzouni, Lukas H Margaritis, Leonidas Stefanis, Kostas Vekrellis. J Neurosci 2010
766
7

Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein.
Paula Desplats, He-Jin Lee, Eun-Jin Bae, Christina Patrick, Edward Rockenstein, Leslie Crews, Brian Spencer, Eliezer Masliah, Seung-Jae Lee. Proc Natl Acad Sci U S A 2009
7

Cryo-EM of full-length α-synuclein reveals fibril polymorphs with a common structural kernel.
Binsen Li, Peng Ge, Kevin A Murray, Phorum Sheth, Meng Zhang, Gayatri Nair, Michael R Sawaya, Woo Shik Shin, David R Boyer, Shulin Ye,[...]. Nat Commun 2018
280
7

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease.
R Krüger, W Kuhn, T Müller, D Woitalla, M Graeber, S Kösel, H Przuntek, J T Epplen, L Schöls, O Riess. Nat Genet 1998
7

Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice.
Kelvin C Luk, Victoria M Kehm, Bin Zhang, Patrick O'Brien, John Q Trojanowski, Virginia M Y Lee. J Exp Med 2012
716
7

Structures of α-synuclein filaments from multiple system atrophy.
Manuel Schweighauser, Yang Shi, Airi Tarutani, Fuyuki Kametani, Alexey G Murzin, Bernardino Ghetti, Tomoyasu Matsubara, Taisuke Tomita, Takashi Ando, Kazuko Hasegawa,[...]. Nature 2020
238
7


Direct observation of the interconversion of normal and toxic forms of α-synuclein.
Nunilo Cremades, Samuel I A Cohen, Emma Deas, Andrey Y Abramov, Allen Y Chen, Angel Orte, Massimo Sandal, Richard W Clarke, Paul Dunne, Francesco A Aprile,[...]. Cell 2012
568
7

α-synuclein oligomers and fibrils: a spectrum of species, a spectrum of toxicities.
Parvez Alam, Luc Bousset, Ronald Melki, Daniel E Otzen. J Neurochem 2019
119
6

α-Synuclein strains cause distinct synucleinopathies after local and systemic administration.
W Peelaerts, L Bousset, A Van der Perren, A Moskalyuk, R Pulizzi, M Giugliano, C Van den Haute, R Melki, V Baekelandt. Nature 2015
726
6

Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
Manuela Neumann, Deepak M Sampathu, Linda K Kwong, Adam C Truax, Matthew C Micsenyi, Thomas T Chou, Jennifer Bruce, Theresa Schuck, Murray Grossman, Christopher M Clark,[...]. Science 2006
6

Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium.
Ian G McKeith, Bradley F Boeve, Dennis W Dickson, Glenda Halliday, John-Paul Taylor, Daniel Weintraub, Dag Aarsland, James Galvin, Johannes Attems, Clive G Ballard,[...]. Neurology 2017
6

The Synucleinopathies: Twenty Years On.
Michel Goedert, Ross Jakes, Maria Grazia Spillantini. J Parkinsons Dis 2017
239
6

Cellular milieu imparts distinct pathological α-synuclein strains in α-synucleinopathies.
Chao Peng, Ronald J Gathagan, Dustin J Covell, Coraima Medellin, Anna Stieber, John L Robinson, Bin Zhang, Rose M Pitkin, Modupe F Olufemi, Kelvin C Luk,[...]. Nature 2018
317
6

Discriminating α-synuclein strains in Parkinson's disease and multiple system atrophy.
Mohammad Shahnawaz, Abhisek Mukherjee, Sandra Pritzkow, Nicolas Mendez, Prakruti Rabadia, Xiangan Liu, Bo Hu, Ann Schmeichel, Wolfgang Singer, Gang Wu,[...]. Nature 2020
251
6

The Lewy body in Parkinson's disease: molecules implicated in the formation and degradation of alpha-synuclein aggregates.
Koichi Wakabayashi, Kunikazu Tanji, Fumiaki Mori, Hitoshi Takahashi. Neuropathology 2007
284
6

Neuron-released oligomeric α-synuclein is an endogenous agonist of TLR2 for paracrine activation of microglia.
Changyoun Kim, Dong-Hwan Ho, Ji-Eun Suk, Sungyong You, Sarah Michael, Junghee Kang, Sung Joong Lee, Eliezer Masliah, Daehee Hwang, He-Jin Lee,[...]. Nat Commun 2013
494
6

Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies.
Mike A Nalls, Cornelis Blauwendraat, Costanza L Vallerga, Karl Heilbron, Sara Bandres-Ciga, Diana Chang, Manuela Tan, Demis A Kia, Alastair J Noyce, Angli Xue,[...]. Lancet Neurol 2019
625
6

Clinical progression in Parkinson disease and the neurobiology of axons.
Hsiao-Chun Cheng, Christina M Ulane, Robert E Burke. Ann Neurol 2010
528
6

NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded.
P H Weinreb, W Zhen, A W Poon, K A Conway, P T Lansbury. Biochemistry 1996
6

Cell Biology and Pathophysiology of α-Synuclein.
Jacqueline Burré, Manu Sharma, Thomas C Südhof. Cold Spring Harb Perspect Med 2018
202
6


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.