A citation-based method for searching scientific literature

E Roessler, E Belloni, K Gaudenz, F Vargas, S W Scherer, L C Tsui, M Muenke. Hum Mol Genet 1997
Times Cited: 131







List of co-cited articles
970 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Mutations in the human Sonic Hedgehog gene cause holoprosencephaly.
E Roessler, E Belloni, K Gaudenz, P Jay, P Berta, S W Scherer, L C Tsui, M Muenke. Nat Genet 1996
841
60

The mutational spectrum of the sonic hedgehog gene in holoprosencephaly: SHH mutations cause a significant proportion of autosomal dominant holoprosencephaly.
L Nanni, J E Ming, M Bocian, K Steinhaus, D W Bianchi, C Die-Smulders, A Giannotti, K Imaizumi, K L Jones, M D Campo,[...]. Hum Mol Genet 1999
258
43

Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function.
C Chiang, Y Litingtung, E Lee, K E Young, J L Corden, H Westphal, P A Beachy. Nature 1996
35

Mutations in TGIF cause holoprosencephaly and link NODAL signalling to human neural axis determination.
K W Gripp, D Wotton, M C Edwards, E Roessler, L Ades, P Meinecke, A Richieri-Costa, E H Zackai, J Massagué, M Muenke,[...]. Nat Genet 2000
300
27

Holoprosencephaly due to mutations in ZIC2, a homologue of Drosophila odd-paired.
S A Brown, D Warburton, L Y Brown, C Y Yu, E R Roeder, S Stengel-Rutkowski, R C Hennekam, M Muenke. Nat Genet 1998
365
26


Identification of Sonic hedgehog as a candidate gene responsible for holoprosencephaly.
E Belloni, M Muenke, E Roessler, G Traverso, J Siegel-Bartelt, A Frumkin, H F Mitchell, H Donis-Keller, C Helms, A V Hing,[...]. Nat Genet 1996
487
26

Mutations in the homeodomain of the human SIX3 gene cause holoprosencephaly.
D E Wallis, E Roessler, U Hehr, L Nanni, T Wiltshire, A Richieri-Costa, G Gillessen-Kaesbach, E H Zackai, J Rommens, M Muenke. Nat Genet 1999
283
23

Expression of the Sonic hedgehog (SHH ) gene during early human development and phenotypic expression of new mutations causing holoprosencephaly.
S Odent, T Atti-Bitach, M Blayau, M Mathieu, J Aug, A L Delezo de, J Y Gall, B Le Marec, A Munnich, V David,[...]. Hum Mol Genet 1999
110
21


Loss-of-function mutations in the human GLI2 gene are associated with pituitary anomalies and holoprosencephaly-like features.
Erich Roessler, Yang-Zhu Du, Jose L Mullor, Esther Casas, William P Allen, Gabriele Gillessen-Kaesbach, Elizabeth R Roeder, Jeffrey E Ming, Ariel Ruiz i Altaba, Maximilian Muenke. Proc Natl Acad Sci U S A 2003
235
21


Mutations in PATCHED-1, the receptor for SONIC HEDGEHOG, are associated with holoprosencephaly.
Jeffrey E Ming, Michelle E Kaupas, Erich Roessler, Han G Brunner, Mahin Golabi, Mustafa Tekin, Robert F Stratton, Eva Sujansky, Sherri J Bale, Maximilian Muenke. Hum Genet 2002
158
20

Identification of a palmitic acid-modified form of human Sonic hedgehog.
R B Pepinsky, C Zeng, D Wen, P Rayhorn, D P Baker, K P Williams, S A Bixler, C M Ambrose, E A Garber, K Miatkowski,[...]. J Biol Chem 1998
518
19

Skinny hedgehog, an acyltransferase required for palmitoylation and activity of the hedgehog signal.
Z Chamoun, R K Mann, D Nellen, D P von Kessler, M Bellotto, P A Beachy, K Basler. Science 2001
300
18


Molecular screening of SHH, ZIC2, SIX3, and TGIF genes in patients with features of holoprosencephaly spectrum: Mutation review and genotype-phenotype correlations.
Christèle Dubourg, Leïla Lazaro, Laurent Pasquier, Claude Bendavid, Martine Blayau, Franck Le Duff, Marie-Renée Durou, Sylvie Odent, Véronique David. Hum Mutat 2004
115
17

Linkage of a human brain malformation, familial holoprosencephaly, to chromosome 7 and evidence for genetic heterogeneity.
M Muenke, F Gurrieri, C Bay, D H Yi, A L Collins, V P Johnson, R C Hennekam, G B Schaefer, L Weik, M S Lubinsky. Proc Natl Acad Sci U S A 1994
107
16

Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity.
Y Echelard, D J Epstein, B St-Jacques, L Shen, J Mohler, J A McMahon, A P McMahon. Cell 1993
16

Hedgehog-mediated patterning of the mammalian embryo requires transporter-like function of dispatched.
Yong Ma, Alfrun Erkner, Ruoyu Gong, Shenqin Yao, Jussi Taipale, Konrad Basler, Philip A Beachy. Cell 2002
217
16



SHH mutation is associated with solitary median maxillary central incisor: a study of 13 patients and review of the literature.
L Nanni, J E Ming, Y Du, R K Hall, M Aldred, A Bankier, M Muenke. Am J Med Genet 2001
97
15

Hedgehog patterning activity: role of a lipophilic modification mediated by the carboxy-terminal autoprocessing domain.
J A Porter, S C Ekker, W J Park, D P von Kessler, K E Young, C H Chen, Y Ma, A S Woods, R J Cotter, E V Koonin,[...]. Cell 1996
397
14

Holoprosencephaly due to mutations in ZIC2: alanine tract expansion mutations may be caused by parental somatic recombination.
L Y Brown, S Odent, V David, M Blayau, C Dubourg, C Apacik, M A Delgado, B D Hall, J F Reynolds, A Sommer,[...]. Hum Mol Genet 2001
137
14

Holoprosencephaly in RSH/Smith-Lemli-Opitz syndrome: does abnormal cholesterol metabolism affect the function of Sonic Hedgehog?
R L Kelley, E Roessler, R C Hennekam, G L Feldman, K Kosaki, M C Jones, J C Palumbos, M Muenke. Am J Med Genet 1996
166
13

A loss-of-function mutation in the CFC domain of TDGF1 is associated with human forebrain defects.
June M de la Cruz, Richard N Bamford, Rebecca D Burdine, Erich Roessler, A James Barkovich, Dian Donnai, Alexander F Schier, Maximilian Muenke. Hum Genet 2002
80
16

A freely diffusible form of Sonic hedgehog mediates long-range signalling.
X Zeng, J A Goetz, L M Suber, W J Scott, C M Schreiner, D J Robbins. Nature 2001
336
13

Biochemical evidence that patched is the Hedgehog receptor.
V Marigo, R A Davey, Y Zuo, J M Cunningham, C J Tabin. Nature 1996
661
12

Cytogenetic rearrangements involving the loss of the Sonic Hedgehog gene at 7q36 cause holoprosencephaly.
E Roessler, D E Ward, K Gaudenz, E Belloni, S W Scherer, D Donnai, J Siegel-Bartelt, L C Tsui, M Muenke. Hum Genet 1997
89
13

Holoprosencephaly: from Homer to Hedgehog.
J E Ming, M Muenke. Clin Genet 1998
98
12

Genetics of ventral forebrain development and holoprosencephaly.
M Muenke, P A Beachy. Curr Opin Genet Dev 2000
197
12

Teratogenesis of holoprosencephaly.
M Michael Cohen, Kohei Shiota. Am J Med Genet 2002
130
12


Autoproteolysis in hedgehog protein biogenesis.
J J Lee, S C Ekker, D P von Kessler, J A Porter, B I Sun, P A Beachy. Science 1994
423
11



Molecular mechanisms of holoprosencephaly.
D E Wallis, M Muenke. Mol Genet Metab 1999
99
11

The product of hedgehog autoproteolytic cleavage active in local and long-range signalling.
J A Porter, D P von Kessler, S C Ekker, K E Young, J J Lee, K Moses, P A Beachy. Nature 1995
413
11

Crystal structure of a Hedgehog autoprocessing domain: homology between Hedgehog and self-splicing proteins.
T M Hall, J A Porter, K E Young, E V Koonin, P A Beachy, D J Leahy. Cell 1997
205
11

Novel mutation in sonic hedgehog in non-syndromic colobomatous microphthalmia.
Lisa A Schimmenti, June de la Cruz, Richard Alan Lewis, J D Karkera, Glenda S Manligas, Erich Roessler, Maximilian Muenke. Am J Med Genet A 2003
111
11


A Smad transcriptional corepressor.
D Wotton, R S Lo, S Lee, J Massagué. Cell 1999
448
10


Sonic hedgehog mediates the polarizing activity of the ZPA.
R D Riddle, R L Johnson, E Laufer, C Tabin. Cell 1993
10

Identification of novel mutations in SHH and ZIC2 in a South American (ECLAMC) population with holoprosencephaly.
I M Orioli, E E Castilla, J E Ming, J Nazer, M J Burle de Aguiar, J C Llerena, M Muenke. Hum Genet 2001
41
24

Altered neural cell fates and medulloblastoma in mouse patched mutants.
L V Goodrich, L Milenković, K M Higgins, M P Scott. Science 1997
10


Cholesterol modification of sonic hedgehog is required for long-range signaling activity and effective modulation of signaling by Ptc1.
P M Lewis, M P Dunn, J A McMahon, M Logan, J F Martin, B St-Jacques, A P McMahon. Cell 2001
374
10

Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened.
James K Chen, Jussi Taipale, Michael K Cooper, Philip A Beachy. Genes Dev 2002
10


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.