A citation-based method for searching scientific literature

S M Gu, D A Thompson, C R Srikumari, B Lorenz, U Finckh, A Nicoletti, K R Murthy, M Rathmann, G Kumaramanickavel, M J Denton, A Gal. Nat Genet 1997
Times Cited: 501







List of co-cited articles
1208 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Mutations in RPE65 cause Leber's congenital amaurosis.
F Marlhens, C Bareil, J M Griffoin, E Zrenner, P Amalric, C Eliaou, S Y Liu, E Harris, T M Redmond, B Arnaud,[...]. Nat Genet 1997
495
44

Safety and efficacy of gene transfer for Leber's congenital amaurosis.
Albert M Maguire, Francesca Simonelli, Eric A Pierce, Edward N Pugh, Federico Mingozzi, Jeannette Bennicelli, Sandro Banfi, Kathleen A Marshall, Francesco Testa, Enrico M Surace,[...]. N Engl J Med 2008
36

Rpe65 is necessary for production of 11-cis-vitamin A in the retinal visual cycle.
T M Redmond, S Yu, E Lee, D Bok, D Hamasaki, N Chen, P Goletz, J X Ma, R K Crouch, K Pfeifer. Nat Genet 1998
751
34

Efficacy and safety of voretigene neparvovec (AAV2-hRPE65v2) in patients with RPE65-mediated inherited retinal dystrophy: a randomised, controlled, open-label, phase 3 trial.
Stephen Russell, Jean Bennett, Jennifer A Wellman, Daniel C Chung, Zi-Fan Yu, Amy Tillman, Janet Wittes, Julie Pappas, Okan Elci, Sarah McCague,[...]. Lancet 2017
783
34

Effect of gene therapy on visual function in Leber's congenital amaurosis.
James W B Bainbridge, Alexander J Smith, Susie S Barker, Scott Robbie, Robert Henderson, Kamaljit Balaggan, Ananth Viswanathan, Graham E Holder, Andrew Stockman, Nick Tyler,[...]. N Engl J Med 2008
32

Mutations in the RPE65 gene in patients with autosomal recessive retinitis pigmentosa or leber congenital amaurosis.
H Morimura, G A Fishman, S A Grover, A B Fulton, E L Berson, T P Dryja. Proc Natl Acad Sci U S A 1998
358
31

Long-term effect of gene therapy on Leber's congenital amaurosis.
James W B Bainbridge, Manjit S Mehat, Venki Sundaram, Scott J Robbie, Susie E Barker, Caterina Ripamonti, Anastasios Georgiadis, Freya M Mowat, Stuart G Beattie, Peter J Gardner,[...]. N Engl J Med 2015
474
22

RPE65 is the isomerohydrolase in the retinoid visual cycle.
Gennadiy Moiseyev, Ying Chen, Yusuke Takahashi, Bill X Wu, Jian-Xing Ma. Proc Natl Acad Sci U S A 2005
388
21

Leber congenital amaurosis: genes, proteins and disease mechanisms.
Anneke I den Hollander, Ronald Roepman, Robert K Koenekoop, Frans P M Cremers. Prog Retin Eye Res 2008
559
20

Gene therapy restores vision in a canine model of childhood blindness.
G M Acland, G D Aguirre, J Ray, Q Zhang, T S Aleman, A V Cideciyan, S E Pearce-Kelling, V Anand, Y Zeng, A M Maguire,[...]. Nat Genet 2001
867
20

Treatment of leber congenital amaurosis due to RPE65 mutations by ocular subretinal injection of adeno-associated virus gene vector: short-term results of a phase I trial.
William W Hauswirth, Tomas S Aleman, Shalesh Kaushal, Artur V Cideciyan, Sharon B Schwartz, Lili Wang, Thomas J Conlon, Sanford L Boye, Terence R Flotte, Barry J Byrne,[...]. Hum Gene Ther 2008
733
19

Retinitis pigmentosa.
Dyonne T Hartong, Eliot L Berson, Thaddeus P Dryja. Lancet 2006
19

Mutation of key residues of RPE65 abolishes its enzymatic role as isomerohydrolase in the visual cycle.
T Michael Redmond, Eugenia Poliakov, Shirley Yu, Jen-Yue Tsai, Zhongjian Lu, Susan Gentleman. Proc Natl Acad Sci U S A 2005
315
18

Safety and durability of effect of contralateral-eye administration of AAV2 gene therapy in patients with childhood-onset blindness caused by RPE65 mutations: a follow-on phase 1 trial.
Jean Bennett, Jennifer Wellman, Kathleen A Marshall, Sarah McCague, Manzar Ashtari, Julie DiStefano-Pappas, Okan U Elci, Daniel C Chung, Junwei Sun, J Fraser Wright,[...]. Lancet 2016
268
18

Human retinal gene therapy for Leber congenital amaurosis shows advancing retinal degeneration despite enduring visual improvement.
Artur V Cideciyan, Samuel G Jacobson, William A Beltran, Alexander Sumaroka, Malgorzata Swider, Simone Iwabe, Alejandro J Roman, Melani B Olivares, Sharon B Schwartz, András M Komáromy,[...]. Proc Natl Acad Sci U S A 2013
310
18

Genetics and phenotypes of RPE65 mutations in inherited retinal degeneration.
D A Thompson, P Gyürüs, L L Fleischer, E L Bingham, C L McHenry, E Apfelstedt-Sylla, E Zrenner, B Lorenz, J E Richards, S G Jacobson,[...]. Invest Ophthalmol Vis Sci 2000
196
17

Human gene therapy for RPE65 isomerase deficiency activates the retinoid cycle of vision but with slow rod kinetics.
Artur V Cideciyan, Tomas S Aleman, Sanford L Boye, Sharon B Schwartz, Shalesh Kaushal, Alejandro J Roman, Ji-Jing Pang, Alexander Sumaroka, Elizabeth A M Windsor, James M Wilson,[...]. Proc Natl Acad Sci U S A 2008
540
17

Age-dependent effects of RPE65 gene therapy for Leber's congenital amaurosis: a phase 1 dose-escalation trial.
Albert M Maguire, Katherine A High, Alberto Auricchio, J Fraser Wright, Eric A Pierce, Francesco Testa, Federico Mingozzi, Jeannette L Bennicelli, Gui-shuang Ying, Settimio Rossi,[...]. Lancet 2009
601
17

The Natural History of Inherited Retinal Dystrophy Due to Biallelic Mutations in the RPE65 Gene.
Daniel C Chung, Mette Bertelsen, Birgit Lorenz, Mark E Pennesi, Bart P Leroy, Christian P Hamel, Eric Pierce, Juliana Sallum, Michael Larsen, Knut Stieger,[...]. Am J Ophthalmol 2019
46
32

Rpe65 is the retinoid isomerase in bovine retinal pigment epithelium.
Minghao Jin, Songhua Li, Walid N Moghrabi, Hui Sun, Gabriel H Travis. Cell 2005
339
14

A comprehensive clinical and biochemical functional study of a novel RPE65 hypomorphic mutation.
Birgit Lorenz, Eugenia Poliakov, Maria Schambeck, Christoph Friedburg, Markus N Preising, T Michael Redmond. Invest Ophthalmol Vis Sci 2008
60
23

Longitudinal and cross-sectional study of patients with early-onset severe retinal dystrophy associated with RPE65 mutations.
Karina Paunescu, Bettina Wabbels, Markus N Preising, Birgit Lorenz. Graefes Arch Clin Exp Ophthalmol 2005
65
20

Lack of fundus autofluorescence to 488 nanometers from childhood on in patients with early-onset severe retinal dystrophy associated with mutations in RPE65.
Birgit Lorenz, Bettina Wabbels, Erika Wegscheider, Christian P Hamel, Wolfgang Drexler, Markus N Preising. Ophthalmology 2004
103
13

Diseases caused by defects in the visual cycle: retinoids as potential therapeutic agents.
Gabriel H Travis, Marcin Golczak, Alexander R Moise, Krzysztof Palczewski. Annu Rev Pharmacol Toxicol 2007
292
13

Improvement and decline in vision with gene therapy in childhood blindness.
Samuel G Jacobson, Artur V Cideciyan, Alejandro J Roman, Alexander Sumaroka, Sharon B Schwartz, Elise Heon, William W Hauswirth. N Engl J Med 2015
250
13

Gene therapy for leber congenital amaurosis caused by RPE65 mutations: safety and efficacy in 15 children and adults followed up to 3 years.
Samuel G Jacobson, Artur V Cideciyan, Ramakrishna Ratnakaram, Elise Heon, Sharon B Schwartz, Alejandro J Roman, Marc C Peden, Tomas S Aleman, Sanford L Boye, Alexander Sumaroka,[...]. Arch Ophthalmol 2012
445
13

Mutations in the gene encoding lecithin retinol acyltransferase are associated with early-onset severe retinal dystrophy.
D A Thompson, Y Li, C L McHenry, T J Carlson, X Ding, P A Sieving, E Apfelstedt-Sylla, A Gal. Nat Genet 2001
143
12

Long-term restoration of rod and cone vision by single dose rAAV-mediated gene transfer to the retina in a canine model of childhood blindness.
Gregory M Acland, Gustavo D Aguirre, Jean Bennett, Tomas S Aleman, Artur V Cideciyan, Jeannette Bennicelli, Nadine S Dejneka, Susan E Pearce-Kelling, Albert M Maguire, Krzysztof Palczewski,[...]. Mol Ther 2005
339
12

Defining the residual vision in leber congenital amaurosis caused by RPE65 mutations.
Samuel G Jacobson, Tomas S Aleman, Artur V Cideciyan, Alejandro J Roman, Alexander Sumaroka, Elizabeth A M Windsor, Sharon B Schwartz, Elise Heon, Edwin M Stone. Invest Ophthalmol Vis Sci 2009
97
12

Leber congenital amaurosis: comprehensive survey of the genetic heterogeneity, refinement of the clinical definition, and genotype-phenotype correlations as a strategy for molecular diagnosis.
Sylvain Hanein, Isabelle Perrault, Sylvie Gerber, Gaëlle Tanguy, Fabienne Barbet, Dominique Ducroq, Patrick Calvas, Hélène Dollfus, Christian Hamel, Tuija Lopponen,[...]. Hum Mutat 2004
264
12

Results at 2 Years after Gene Therapy for RPE65-Deficient Leber Congenital Amaurosis and Severe Early-Childhood-Onset Retinal Dystrophy.
Richard G Weleber, Mark E Pennesi, David J Wilson, Shalesh Kaushal, Laura R Erker, Lauren Jensen, Maureen T McBride, Terence R Flotte, Margaret Humphries, Roberto Calcedo,[...]. Ophthalmology 2016
119
12

Identifying photoreceptors in blind eyes caused by RPE65 mutations: Prerequisite for human gene therapy success.
Samuel G Jacobson, Tomas S Aleman, Artur V Cideciyan, Alexander Sumaroka, Sharon B Schwartz, Elizabeth A M Windsor, Elias I Traboulsi, Elise Heon, Steven J Pittler, Ann H Milam,[...]. Proc Natl Acad Sci U S A 2005
213
12


Comprehensive genotyping reveals RPE65 as the most frequently mutated gene in Leber congenital amaurosis in Denmark.
Galuh D N Astuti, Mette Bertelsen, Markus N Preising, Muhammad Ajmal, Birgit Lorenz, Sultana M H Faradz, Raheel Qamar, Rob W J Collin, Thomas Rosenberg, Frans P M Cremers. Eur J Hum Genet 2016
44
27

Gene therapy for Leber's congenital amaurosis is safe and effective through 1.5 years after vector administration.
Francesca Simonelli, Albert M Maguire, Francesco Testa, Eric A Pierce, Federico Mingozzi, Jeannette L Bennicelli, Settimio Rossi, Kathleen Marshall, Sandro Banfi, Enrico M Surace,[...]. Mol Ther 2010
394
11

Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology.
Sue Richards, Nazneen Aziz, Sherri Bale, David Bick, Soma Das, Julie Gastier-Foster, Wayne W Grody, Madhuri Hegde, Elaine Lyon, Elaine Spector,[...]. Genet Med 2015
11

Mutations in MERTK, the human orthologue of the RCS rat retinal dystrophy gene, cause retinitis pigmentosa.
A Gal, Y Li, D A Thompson, J Weir, U Orth, S G Jacobson, E Apfelstedt-Sylla, D Vollrath. Nat Genet 2000
520
11

The phenotype of Severe Early Childhood Onset Retinal Dystrophy (SECORD) from mutation of RPE65 and differentiation from Leber congenital amaurosis.
Richard G Weleber, Michel Michaelides, Karmen M Trzupek, Niamh B Stover, Edwin M Stone. Invest Ophthalmol Vis Sci 2011
50
22

Human cone photoreceptor dependence on RPE65 isomerase.
Samuel G Jacobson, Tomas S Aleman, Artur V Cideciyan, Elise Heon, Marcin Golczak, William A Beltran, Alexander Sumaroka, Sharon B Schwartz, Alejandro J Roman, Elizabeth A M Windsor,[...]. Proc Natl Acad Sci U S A 2007
118
11

Non-syndromic retinitis pigmentosa.
Sanne K Verbakel, Ramon A C van Huet, Camiel J F Boon, Anneke I den Hollander, Rob W J Collin, Caroline C W Klaver, Carel B Hoyng, Ronald Roepman, B Jeroen Klevering. Prog Retin Eye Res 2018
336
11

A dominant mutation in RPE65 identified by whole-exome sequencing causes retinitis pigmentosa with choroidal involvement.
Sara J Bowne, Marian M Humphries, Lori S Sullivan, Paul F Kenna, Lawrence C S Tam, Anna S Kiang, Matthew Campbell, George M Weinstock, Daniel C Koboldt, Li Ding,[...]. Eur J Hum Genet 2011
106
10


Early-onset severe rod-cone dystrophy in young children with RPE65 mutations.
B Lorenz, P Gyürüs, M Preising, D Bremser, S Gu, M Andrassi, C Gerth, A Gal. Invest Ophthalmol Vis Sci 2000
153
10

Three-year follow-up after unilateral subretinal delivery of adeno-associated virus in patients with Leber congenital Amaurosis type 2.
Francesco Testa, Albert M Maguire, Settimio Rossi, Eric A Pierce, Paolo Melillo, Kathleen Marshall, Sandro Banfi, Enrico M Surace, Junwei Sun, Carmela Acerra,[...]. Ophthalmology 2013
230
10

Efficacy, Safety, and Durability of Voretigene Neparvovec-rzyl in RPE65 Mutation-Associated Inherited Retinal Dystrophy: Results of Phase 1 and 3 Trials.
Albert M Maguire, Stephen Russell, Jennifer A Wellman, Daniel C Chung, Zi-Fan Yu, Amy Tillman, Janet Wittes, Julie Pappas, Okan Elci, Kathleen A Marshall,[...]. Ophthalmology 2019
155
10

The clinical features of retinal disease due to a dominant mutation in RPE65.
Sarah Hull, Rajarshi Mukherjee, Graham E Holder, Anthony T Moore, Andrew R Webster. Mol Vis 2016
29
31

AAV2 gene therapy readministration in three adults with congenital blindness.
Jean Bennett, Manzar Ashtari, Jennifer Wellman, Kathleen A Marshall, Laura L Cyckowski, Daniel C Chung, Sarah McCague, Eric A Pierce, Yifeng Chen, Jeannette L Bennicelli,[...]. Sci Transl Med 2012
285
9

Congenital stationary night blindness in the dog: common mutation in the RPE65 gene indicates founder effect.
G D Aguirre, V Baldwin, S Pearce-Kelling, K Narfström, K Ray, G M Acland. Mol Vis 1998
149
9

Lecithin-retinol acyltransferase is essential for accumulation of all-trans-retinyl esters in the eye and in the liver.
Matthew L Batten, Yoshikazu Imanishi, Tadao Maeda, Daniel C Tu, Alexander R Moise, Darin Bronson, Daniel Possin, Russell N Van Gelder, Wolfgang Baehr, Krzysztof Palczewski. J Biol Chem 2004
276
9

Fundus albipunctatus associated with compound heterozygous mutations in RPE65.
Patrik Schatz, Markus Preising, Birgit Lorenz, Birgit Sander, Michael Larsen, Thomas Rosenberg. Ophthalmology 2011
45
20


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.