A citation-based method for searching scientific literature

L A Farrer, L A Cupples, J L Haines, B Hyman, W A Kukull, R Mayeux, R H Myers, M A Pericak-Vance, N Risch, C M van Duijn. JAMA 1997
Times Cited: 2561







List of co-cited articles
1094 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families.
E H Corder, A M Saunders, W J Strittmatter, D E Schmechel, P C Gaskell, G W Small, A D Roses, J L Haines, M A Pericak-Vance. Science 1993
30

Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.
Brian W Kunkle, Benjamin Grenier-Boley, Rebecca Sims, Joshua C Bis, Vincent Damotte, Adam C Naj, Anne Boland, Maria Vronskaya, Sven J van der Lee, Alexandre Amlie-Wolf,[...]. Nat Genet 2019
950
19

Sex modifies the APOE-related risk of developing Alzheimer disease.
Andre Altmann, Lu Tian, Victor W Henderson, Michael D Greicius. Ann Neurol 2014
409
17

Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study.
Eric M Reiman, Joseph F Arboleda-Velasquez, Yakeel T Quiroz, Matthew J Huentelman, Thomas G Beach, Richard J Caselli, Yinghua Chen, Yi Su, Amanda J Myers, John Hardy,[...]. Nat Commun 2020
125
17

A Quarter Century of APOE and Alzheimer's Disease: Progress to Date and the Path Forward.
Michaël E Belloy, Valerio Napolioni, Michael D Greicius. Neuron 2019
181
16

Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy.
Chia-Chen Liu, Chia-Chan Liu, Takahisa Kanekiyo, Huaxi Xu, Guojun Bu. Nat Rev Neurol 2013
15

Apolipoprotein E and Alzheimer disease: pathobiology and targeting strategies.
Yu Yamazaki, Na Zhao, Thomas R Caulfield, Chia-Chen Liu, Guojun Bu. Nat Rev Neurol 2019
339
14

Apolipoprotein E Genotype and Sex Risk Factors for Alzheimer Disease: A Meta-analysis.
Scott C Neu, Judy Pa, Walter Kukull, Duane Beekly, Amanda Kuzma, Prabhakaran Gangadharan, Li-San Wang, Klaus Romero, Stephen P Arneric, Alberto Redolfi,[...]. JAMA Neurol 2017
276
13

Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease.
E H Corder, A M Saunders, N J Risch, W J Strittmatter, D E Schmechel, P C Gaskell, J B Rimmler, P A Locke, P M Conneally, K E Schmader. Nat Genet 1994
13

NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease.
Clifford R Jack, David A Bennett, Kaj Blennow, Maria C Carrillo, Billy Dunn, Samantha Budd Haeberlein, David M Holtzman, William Jagust, Frank Jessen, Jason Karlawish,[...]. Alzheimers Dement 2018
12

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
J C Lambert, C A Ibrahim-Verbaas, D Harold, A C Naj, R Sims, C Bellenguez, A L DeStafano, J C Bis, G W Beecham, B Grenier-Boley,[...]. Nat Genet 2013
12


ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy.
Yang Shi, Kaoru Yamada, Shane Antony Liddelow, Scott T Smith, Lingzhi Zhao, Wenjie Luo, Richard M Tsai, Salvatore Spina, Lea T Grinberg, Julio C Rojas,[...]. Nature 2017
529
11

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease.
W J Strittmatter, A M Saunders, D Schmechel, M Pericak-Vance, J Enghild, G S Salvesen, A D Roses. Proc Natl Acad Sci U S A 1993
11

Age, APOE and sex: Triad of risk of Alzheimer's disease.
Brandalyn C Riedel, Paul M Thompson, Roberta Diaz Brinton. J Steroid Biochem Mol Biol 2016
254
10

Human apoE isoforms differentially regulate brain amyloid-β peptide clearance.
Joseph M Castellano, Jungsu Kim, Floy R Stewart, Hong Jiang, Ronald B DeMattos, Bruce W Patterson, Anne M Fagan, John C Morris, Kwasi G Mawuenyega, Carlos Cruchaga,[...]. Sci Transl Med 2011
706
10

Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease.
A M Saunders, W J Strittmatter, D Schmechel, P H George-Hyslop, M A Pericak-Vance, S H Joo, B L Rosi, J F Gusella, D R Crapper-MacLachlan, M J Alberts. Neurology 1993
10

APOE and Alzheimer disease: a major gene with semi-dominant inheritance.
E Genin, D Hannequin, D Wallon, K Sleegers, M Hiltunen, O Combarros, M J Bullido, S Engelborghs, P De Deyn, C Berr,[...]. Mol Psychiatry 2011
372
10

Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
Iris E Jansen, Jeanne E Savage, Kyoko Watanabe, Julien Bryois, Dylan M Williams, Stacy Steinberg, Julia Sealock, Ida K Karlsson, Sara Hägg, Lavinia Athanasiu,[...]. Nat Genet 2019
782
10

Sex-Specific Association of Apolipoprotein E With Cerebrospinal Fluid Levels of Tau.
Timothy J Hohman, Logan Dumitrescu, Lisa L Barnes, Madhav Thambisetty, Gary Beecham, Brian Kunkle, Katherine A Gifford, William S Bush, Lori B Chibnik, Shubhabrata Mukherjee,[...]. JAMA Neurol 2018
139
9

A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease.
Hadas Keren-Shaul, Amit Spinrad, Assaf Weiner, Orit Matcovitch-Natan, Raz Dvir-Szternfeld, Tyler K Ulland, Eyal David, Kuti Baruch, David Lara-Astaiso, Beata Toth,[...]. Cell 2017
9


Variant of TREM2 associated with the risk of Alzheimer's disease.
Thorlakur Jonsson, Hreinn Stefansson, Stacy Steinberg, Ingileif Jonsdottir, Palmi V Jonsson, Jon Snaedal, Sigurbjorn Bjornsson, Johanna Huttenlocher, Allan I Levey, James J Lah,[...]. N Engl J Med 2013
9

The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease.
Guy M McKhann, David S Knopman, Howard Chertkow, Bradley T Hyman, Clifford R Jack, Claudia H Kawas, William E Klunk, Walter J Koroshetz, Jennifer J Manly, Richard Mayeux,[...]. Alzheimers Dement 2011
9

TREM2 variants in Alzheimer's disease.
Rita Guerreiro, Aleksandra Wojtas, Jose Bras, Minerva Carrasquillo, Ekaterina Rogaeva, Elisa Majounie, Carlos Cruchaga, Celeste Sassi, John S K Kauwe, Steven Younkin,[...]. N Engl J Med 2013
8

Clinical epidemiology of Alzheimer's disease: assessing sex and gender differences.
Michelle M Mielke, Prashanthi Vemuri, Walter A Rocca. Clin Epidemiol 2014
506
8


The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases.
Susanne Krasemann, Charlotte Madore, Ron Cialic, Caroline Baufeld, Narghes Calcagno, Rachid El Fatimy, Lien Beckers, Elaine O'Loughlin, Yang Xu, Zain Fanek,[...]. Immunity 2017
8

Apolipoprotein E: far more than a lipid transport protein.
R W Mahley, S C Rall. Annu Rev Genomics Hum Genet 2000
8

The role of apolipoprotein E in Alzheimer's disease.
Jungsu Kim, Jacob M Basak, David M Holtzman. Neuron 2009
960
8

Apolipoprotein E4 Impairs Neuronal Insulin Signaling by Trapping Insulin Receptor in the Endosomes.
Na Zhao, Chia-Chen Liu, Alexandra J Van Ingelgom, Yuka A Martens, Cynthia Linares, Joshua A Knight, Meghan M Painter, Patrick M Sullivan, Guojun Bu. Neuron 2017
140
8

The APOE-epsilon4 allele and the risk of Alzheimer disease among African Americans, whites, and Hispanics.
M X Tang, Y Stern, K Marder, K Bell, B Gurland, R Lantigua, H Andrews, L Feng, B Tycko, R Mayeux. JAMA 1998
535
8

Apolipoprotein E controls cerebrovascular integrity via cyclophilin A.
Robert D Bell, Ethan A Winkler, Itender Singh, Abhay P Sagare, Rashid Deane, Zhenhua Wu, David M Holtzman, Christer Betsholtz, Annika Armulik, Jan Sallstrom,[...]. Nature 2012
797
8


Sex differences in the association between AD biomarkers and cognitive decline.
Mary Ellen I Koran, Madison Wagener, Timothy J Hohman. Brain Imaging Behav 2017
123
7

Single-cell transcriptomic analysis of Alzheimer's disease.
Hansruedi Mathys, Jose Davila-Velderrain, Zhuyu Peng, Fan Gao, Shahin Mohammadi, Jennie Z Young, Madhvi Menon, Liang He, Fatema Abdurrob, Xueqiao Jiang,[...]. Nature 2019
686
7

The multiplex model of the genetics of Alzheimer's disease.
Rebecca Sims, Matthew Hill, Julie Williams. Nat Neurosci 2020
129
7

Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease.
D E Schmechel, A M Saunders, W J Strittmatter, B J Crain, C M Hulette, S H Joo, M A Pericak-Vance, D Goldgaber, A D Roses. Proc Natl Acad Sci U S A 1993
7

ApoE4 Accelerates Early Seeding of Amyloid Pathology.
Chia-Chen Liu, Na Zhao, Yuan Fu, Na Wang, Cynthia Linares, Chih-Wei Tsai, Guojun Bu. Neuron 2017
157
7


APOE4 leads to blood-brain barrier dysfunction predicting cognitive decline.
Axel Montagne, Daniel A Nation, Abhay P Sagare, Giuseppe Barisano, Melanie D Sweeney, Ararat Chakhoyan, Maricarmen Pachicano, Elizabeth Joe, Amy R Nelson, Lina M D'Orazio,[...]. Nature 2020
358
7

Resistance to autosomal dominant Alzheimer's disease in an APOE3 Christchurch homozygote: a case report.
Joseph F Arboleda-Velasquez, Francisco Lopera, Michael O'Hare, Santiago Delgado-Tirado, Claudia Marino, Natalia Chmielewska, Kahira L Saez-Torres, Dhanesh Amarnani, Aaron P Schultz, Reisa A Sperling,[...]. Nat Med 2019
172
7

Alzheimer's Risk Factors Age, APOE Genotype, and Sex Drive Distinct Molecular Pathways.
Na Zhao, Yingxue Ren, Yu Yamazaki, Wenhui Qiao, Fuyao Li, Lindsey M Felton, Siamak Mahmoudiandehkordi, Alexandra Kueider-Paisley, Berkiye Sonoustoun, Matthias Arnold,[...]. Neuron 2020
63
11

Targeted replacement of the mouse apolipoprotein E gene with the common human APOE3 allele enhances diet-induced hypercholesterolemia and atherosclerosis.
P M Sullivan, H Mezdour, Y Aratani, C Knouff, J Najib, R L Reddick, S H Quarfordt, N Maeda. J Biol Chem 1997
396
7

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease.
Denise Harold, Richard Abraham, Paul Hollingworth, Rebecca Sims, Amy Gerrish, Marian L Hamshere, Jaspreet Singh Pahwa, Valentina Moskvina, Kimberley Dowzell, Amy Williams,[...]. Nat Genet 2009
7

APOE predicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging.
John C Morris, Catherine M Roe, Chengjie Xiong, Anne M Fagan, Alison M Goate, David M Holtzman, Mark A Mintun. Ann Neurol 2010
621
7

Total apolipoprotein E levels and specific isoform composition in cerebrospinal fluid and plasma from Alzheimer's disease patients and controls.
Eduardo Martínez-Morillo, Oskar Hansson, Yuka Atagi, Guojun Bu, Lennart Minthon, Eleftherios P Diamandis, Henrietta M Nielsen. Acta Neuropathol 2014
93
7

Sex differences in Alzheimer disease - the gateway to precision medicine.
Maria Teresa Ferretti, Maria Florencia Iulita, Enrica Cavedo, Patrizia Andrea Chiesa, Annemarie Schumacher Dimech, Antonella Santuccione Chadha, Francesca Baracchi, Hélène Girouard, Sabina Misoch, Ezio Giacobini,[...]. Nat Rev Neurol 2018
290
6

Understanding the impact of sex and gender in Alzheimer's disease: A call to action.
Rebecca A Nebel, Neelum T Aggarwal, Lisa L Barnes, Aimee Gallagher, Jill M Goldstein, Kejal Kantarci, Monica P Mallampalli, Elizabeth C Mormino, Laura Scott, Wai Haung Yu,[...]. Alzheimers Dement 2018
243
6

Alzheimer disease in the United States (2010-2050) estimated using the 2010 census.
Liesi E Hebert, Jennifer Weuve, Paul A Scherr, Denis A Evans. Neurology 2013
6


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.