A citation-based method for searching scientific literature

L de Lecea, T S Kilduff, C Peyron, X Gao, P E Foye, P E Danielson, C Fukuhara, E L Battenberg, V T Gautvik, F S Bartlett, W N Frankel, A N van den Pol, F E Bloom, K M Gautvik, J G Sutcliffe. Proc Natl Acad Sci U S A 1998
Times Cited: 2685







List of co-cited articles
1252 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior.
T Sakurai, A Amemiya, M Ishii, I Matsuzaki, R M Chemelli, H Tanaka, S C Williams, J A Richardson, G P Kozlowski, S Wilson,[...]. Cell 1998
80

Differential expression of orexin receptors 1 and 2 in the rat brain.
J N Marcus, C J Aschkenasi, C E Lee, R M Chemelli, C B Saper, M Yanagisawa, J K Elmquist. J Comp Neurol 2001
34

Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation.
R M Chemelli, J T Willie, C M Sinton, J K Elmquist, T Scammell, C Lee, J A Richardson, S C Williams, Y Xiong, Y Kisanuki,[...]. Cell 1999
24


Genetic ablation of orexin neurons in mice results in narcolepsy, hypophagia, and obesity.
J Hara, C T Beuckmann, T Nambu, J T Willie, R M Chemelli, C M Sinton, F Sugiyama, K Yagami, K Goto, M Yanagisawa,[...]. Neuron 2001
962
21

Distribution of orexin neurons in the adult rat brain.
T Nambu, T Sakurai, K Mizukami, Y Hosoya, M Yanagisawa, K Goto. Brain Res 1999
814
20

Reduced number of hypocretin neurons in human narcolepsy.
T C Thannickal, R Y Moore, R Nienhuis, L Ramanathan, S Gulyani, M Aldrich, M Cornford, J M Siegel. Neuron 2000
20

A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains.
C Peyron, J Faraco, W Rogers, B Ripley, S Overeem, Y Charnay, S Nevsimalova, M Aldrich, D Reynolds, R Albin,[...]. Nat Med 2000
19

The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene.
L Lin, J Faraco, R Li, H Kadotani, W Rogers, X Lin, X Qiu, P J de Jong, S Nishino, E Mignot. Cell 1999
19

A role for lateral hypothalamic orexin neurons in reward seeking.
Glenda C Harris, Mathieu Wimmer, Gary Aston-Jones. Nature 2005
916
18

Neurons containing hypocretin (orexin) project to multiple neuronal systems.
C Peyron, D K Tighe, A N van den Pol, L de Lecea, H C Heller, J G Sutcliffe, T S Kilduff. J Neurosci 1998
17

Hypocretin (orexin) deficiency in human narcolepsy.
S Nishino, B Ripley, S Overeem, G J Lammers, E Mignot. Lancet 2000
16

Orexins, orexigenic hypothalamic peptides, interact with autonomic, neuroendocrine and neuroregulatory systems.
Y Date, Y Ueta, H Yamashita, H Yamaguchi, S Matsukura, K Kangawa, T Sakurai, M Yanagisawa, M Nakazato. Proc Natl Acad Sci U S A 1999
804
15

Distribution of orexin receptor mRNA in the rat brain.
P Trivedi, H Yu, D J MacNeil, L H Van der Ploeg, X M Guan. FEBS Lett 1998
757
15

Neural substrates of awakening probed with optogenetic control of hypocretin neurons.
Antoine R Adamantidis, Feng Zhang, Alexander M Aravanis, Karl Deisseroth, Luis de Lecea. Nature 2007
765
14

Orexin A in the VTA is critical for the induction of synaptic plasticity and behavioral sensitization to cocaine.
Stephanie L Borgland, Sharif A Taha, Federica Sarti, Howard L Fields, Antonello Bonci. Neuron 2006
535
12

Motivational activation: a unifying hypothesis of orexin/hypocretin function.
Stephen V Mahler, David E Moorman, Rachel J Smith, Morgan H James, Gary Aston-Jones. Nat Neurosci 2014
221
12

A key role for orexin in panic anxiety.
Philip L Johnson, William Truitt, Stephanie D Fitz, Pamela E Minick, Amy Dietrich, Sonal Sanghani, Lil Träskman-Bendz, Andrew W Goddard, Lena Brundin, Anantha Shekhar. Nat Med 2010
249
12

Distinct narcolepsy syndromes in Orexin receptor-2 and Orexin null mice: molecular genetic dissection of Non-REM and REM sleep regulatory processes.
Jon T Willie, Richard M Chemelli, Christopher M Sinton, Shigeru Tokita, S Clay Williams, Yaz Y Kisanuki, Jacob N Marcus, Charlotte Lee, Joel K Elmquist, Kristi A Kohlmeier,[...]. Neuron 2003
434
11


Afferents to the orexin neurons of the rat brain.
Kyoko Yoshida, Sarah McCormack, Rodrigo A España, Amanda Crocker, Thomas E Scammell. J Comp Neurol 2006
413
10

The role of orexin in motivated behaviours.
Takeshi Sakurai. Nat Rev Neurosci 2014
240
10

Hypocretin (orexin) loss in Alzheimer's disease.
Rolf Fronczek, Sarita van Geest, Marijke Frölich, Sebastiaan Overeem, Freek W C Roelandse, Gert Jan Lammers, Dick F Swaab. Neurobiol Aging 2012
141
10

Amyloid-beta dynamics are regulated by orexin and the sleep-wake cycle.
Jae-Eun Kang, Miranda M Lim, Randall J Bateman, James J Lee, Liam P Smyth, John R Cirrito, Nobuhiro Fujiki, Seiji Nishino, David M Holtzman. Science 2009
846
10

Gene expression and protein distribution of the orexin-1 receptor in the rat brain and spinal cord.
G J Hervieu, J E Cluderay, D C Harrison, J C Roberts, R A Leslie. Neuroscience 2001
362
10

Orexin/hypocretin receptor signalling cascades.
J P Kukkonen, C S Leonard. Br J Pharmacol 2014
108
10

Arousal and reward: a dichotomy in orexin function.
Glenda C Harris, Gary Aston-Jones. Trends Neurosci 2006
407
9

Hypothalamic orexin neurons regulate arousal according to energy balance in mice.
Akihiro Yamanaka, Carsten T Beuckmann, Jon T Willie, Junko Hara, Natsuko Tsujino, Michihiro Mieda, Makoto Tominaga, Ken ichi Yagami, Fumihiro Sugiyama, Katsutoshi Goto,[...]. Neuron 2003
624
9

Evolution of Orexin Neuropeptide System: Structure and Function.
Shingo Soya, Takeshi Sakurai. Front Neurosci 2020
25
36

Role of orexin-1 receptor mechanisms on compulsive food consumption in a model of binge eating in female rats.
Laura Piccoli, Maria Vittoria Micioni Di Bonaventura, Carlo Cifani, Vivian J A Costantini, Mario Massagrande, Dino Montanari, Prisca Martinelli, Marinella Antolini, Roberto Ciccocioppo, Maurizio Massi,[...]. Neuropsychopharmacology 2012
90
10

Promotion of sleep by targeting the orexin system in rats, dogs and humans.
Catherine Brisbare-Roch, Jasper Dingemanse, Ralf Koberstein, Petra Hoever, Hamed Aissaoui, Susan Flores, Celia Mueller, Oliver Nayler, Joop van Gerven, Sanne L de Haas,[...]. Nat Med 2007
411
9

Narcolepsy - clinical spectrum, aetiopathophysiology, diagnosis and treatment.
Claudio L A Bassetti, Antoine Adamantidis, Denis Burdakov, Fang Han, Steffen Gay, Ulf Kallweit, Ramin Khatami, Frits Koning, Brigitte R Kornum, Gert Jan Lammers,[...]. Nat Rev Neurol 2019
132
9

Hypothalamic regulation of sleep and circadian rhythms.
Clifford B Saper, Thomas E Scammell, Jun Lu. Nature 2005
9

The neurobiological basis of narcolepsy.
Carrie E Mahoney, Andrew Cogswell, Igor J Koralnik, Thomas E Scammell. Nat Rev Neurosci 2019
67
13

Orexin A/hypocretin-1 selectively promotes motivation for positive reinforcers.
Stephanie L Borgland, Shao-Ju Chang, M Scott Bowers, Jennifer L Thompson, Nicole Vittoz, Stan B Floresco, Jonathan Chou, Billy T Chen, Antonello Bonci. J Neurosci 2009
255
9

A Decade of Orexin/Hypocretin and Addiction: Where Are We Now?
Morgan H James, Stephen V Mahler, David E Moorman, Gary Aston-Jones. Curr Top Behav Neurosci 2017
86
9

Input of orexin/hypocretin neurons revealed by a genetically encoded tracer in mice.
Takeshi Sakurai, Ruby Nagata, Akihiro Yamanaka, Hiroko Kawamura, Natsuko Tsujino, Yo Muraki, Haruaki Kageyama, Satoshi Kunita, Satoru Takahashi, Katsutoshi Goto,[...]. Neuron 2005
336
8

The hypocretin (orexin) system: from a neural circuitry perspective.
Shi-Bin Li, Luis de Lecea. Neuropharmacology 2020
30
26

Hypocretin (orexin) facilitates reward by attenuating the antireward effects of its cotransmitter dynorphin in ventral tegmental area.
John W Muschamp, Jonathan A Hollander, Jennifer L Thompson, George Voren, Linda C Hassinger, Sara Onvani, Theodore M Kamenecka, Stephanie L Borgland, Paul J Kenny, William A Carlezon. Proc Natl Acad Sci U S A 2014
158
8


Hypocretin (orexin) loss in Parkinson's disease.
Rolf Fronczek, Sebastiaan Overeem, Sandy Y Y Lee, Ingrid M Hegeman, Johannes van Pelt, Sjoerd G van Duinen, Gert Jan Lammers, Dick F Swaab. Brain 2007
271
8


The hypocretin-orexin system regulates cocaine self-administration via actions on the mesolimbic dopamine system.
Rodrigo A España, Erik B Oleson, Jason L Locke, Bethany R Brookshire, David C S Roberts, Sara R Jones. Eur J Neurosci 2010
170
7

Increased Number and Activity of a Lateral Subpopulation of Hypothalamic Orexin/Hypocretin Neurons Underlies the Expression of an Addicted State in Rats.
Morgan H James, Colin M Stopper, Benjamin A Zimmer, Nikki E Koll, Hannah E Bowrey, Gary Aston-Jones. Biol Psychiatry 2019
69
10

Opiates increase the number of hypocretin-producing cells in human and mouse brain and reverse cataplexy in a mouse model of narcolepsy.
Thomas C Thannickal, Joshi John, Ling Shan, Dick F Swaab, Ming-Fung Wu, Lalini Ramanathan, Ronald McGregor, Keng-Tee Chew, Marcia Cornford, Akihiro Yamanaka,[...]. Sci Transl Med 2018
46
15



Orexins Mediate Sex Differences in the Stress Response and in Cognitive Flexibility.
Laura A Grafe, Amanda Cornfeld, Sandra Luz, Rita Valentino, Seema Bhatnagar. Biol Psychiatry 2017
58
12

Sexually dimorphic expression of prepro-orexin mRNA in the rat hypothalamus.
Olaf Jöhren, Steffi J Neidert, Marco Kummer, Peter Dominiak. Peptides 2002
70
10

Single-cell transcriptomic analysis of the lateral hypothalamic area reveals molecularly distinct populations of inhibitory and excitatory neurons.
Laura E Mickelsen, Mohan Bolisetty, Brock R Chimileski, Akie Fujita, Eric J Beltrami, James T Costanzo, Jacob R Naparstek, Paul Robson, Alexander C Jackson. Nat Neurosci 2019
96
7


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.