A citation-based method for searching scientific literature

R Krüger, W Kuhn, T Müller, D Woitalla, M Graeber, S Kösel, H Przuntek, J T Epplen, L Schöls, O Riess. Nat Genet 1998
Times Cited: 2896







List of co-cited articles
2008 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Mutation in the alpha-synuclein gene identified in families with Parkinson's disease.
M H Polymeropoulos, C Lavedan, E Leroy, S E Ide, A Dehejia, A Dutra, B Pike, H Root, J Rubenstein, R Boyer,[...]. Science 1997
91

The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia.
Juan J Zarranz, Javier Alegre, Juan C Gómez-Esteban, Elena Lezcano, Raquel Ros, Israel Ampuero, Lídice Vidal, Janet Hoenicka, Olga Rodriguez, Begoña Atarés,[...]. Ann Neurol 2004
73

alpha-Synuclein locus triplication causes Parkinson's disease.
A B Singleton, M Farrer, J Johnson, A Singleton, S Hague, J Kachergus, M Hulihan, T Peuralinna, A Dutra, R Nussbaum,[...]. Science 2003
56

G51D α-synuclein mutation causes a novel parkinsonian-pyramidal syndrome.
Suzanne Lesage, Mathieu Anheim, Franck Letournel, Luc Bousset, Aurélie Honoré, Nelly Rozas, Laura Pieri, Karine Madiona, Alexandra Dürr, Ronald Melki,[...]. Ann Neurol 2013
402
43

Alpha-synuclein locus duplication as a cause of familial Parkinson's disease.
Marie-Christine Chartier-Harlin, Jennifer Kachergus, Christophe Roumier, Vincent Mouroux, Xavier Douay, Sarah Lincoln, Clotilde Levecque, Lydie Larvor, Joris Andrieux, Mary Hulihan,[...]. Lancet 2004
42

Alpha-synuclein in Lewy bodies.
M G Spillantini, M L Schmidt, V M Lee, J Q Trojanowski, R Jakes, M Goedert. Nature 1997
40

Alpha-synuclein p.H50Q, a novel pathogenic mutation for Parkinson's disease.
Silke Appel-Cresswell, Carles Vilarino-Guell, Mary Encarnacion, Holly Sherman, Irene Yu, Brinda Shah, David Weir, Christina Thompson, Chelsea Szu-Tu, Joanne Trinh,[...]. Mov Disord 2013
370
36

Novel α-synuclein mutation A53E associated with atypical multiple system atrophy and Parkinson's disease-type pathology.
Petra Pasanen, Liisa Myllykangas, Maija Siitonen, Anna Raunio, Seppo Kaakkola, Jukka Lyytinen, Pentti J Tienari, Minna Pöyhönen, Anders Paetau. Neurobiol Aging 2014
277
30

A novel α-synuclein missense mutation in Parkinson disease.
Christos Proukakis, Christopher G Dudzik, Timothy Brier, Donna S MacKay, J Mark Cooper, Glenn L Millhauser, Henry Houlden, Anthony H Schapira. Neurology 2013
294
23

alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies.
M G Spillantini, R A Crowther, R Jakes, M Hasegawa, M Goedert. Proc Natl Acad Sci U S A 1998
22

Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro.
Jacqueline Burré, Manu Sharma, Theodoros Tsetsenis, Vladimir Buchman, Mark R Etherton, Thomas C Südhof. Science 2010
996
20

Staging of brain pathology related to sporadic Parkinson's disease.
Heiko Braak, Kelly Del Tredici, Udo Rüb, Rob A I de Vos, Ernst N H Jansen Steur, Eva Braak. Neurobiol Aging 2003
20

Lewy pathology in Parkinson's disease consists of crowded organelles and lipid membranes.
Sarah H Shahmoradian, Amanda J Lewis, Christel Genoud, Jürgen Hench, Tim E Moors, Paula P Navarro, Daniel Castaño-Díez, Gabriel Schweighauser, Alexandra Graff-Meyer, Kenneth N Goldie,[...]. Nat Neurosci 2019
240
19

Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes.
W S Davidson, A Jonas, D F Clayton, J M George. J Biol Chem 1998
19

Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system.
A Abeliovich, Y Schmitz, I Fariñas, D Choi-Lundberg, W H Ho, P E Castillo, N Shinsky, J M Verdugo, M Armanini, A Ryan,[...]. Neuron 2000
18

α-Synucleinopathy associated with G51D SNCA mutation: a link between Parkinson's disease and multiple system atrophy?
Aoife P Kiely, Yasmine T Asi, Eleanna Kara, Patricia Limousin, Helen Ling, Patrick Lewis, Christos Proukakis, Niall Quinn, Andrew J Lees, John Hardy,[...]. Acta Neuropathol 2013
260
18

alpha-Synuclein is phosphorylated in synucleinopathy lesions.
Hideo Fujiwara, Masato Hasegawa, Naoshi Dohmae, Akiko Kawashima, Eliezer Masliah, Matthew S Goldberg, Jie Shen, Koji Takio, Takeshi Iwatsubo. Nat Cell Biol 2002
18

α-Synuclein strains cause distinct synucleinopathies after local and systemic administration.
W Peelaerts, L Bousset, A Van der Perren, A Moskalyuk, R Pulizzi, M Giugliano, C Van den Haute, R Melki, V Baekelandt. Nature 2015
649
17

Pathological α-synuclein transmission initiates Parkinson-like neurodegeneration in nontransgenic mice.
Kelvin C Luk, Victoria Kehm, Jenna Carroll, Bin Zhang, Patrick O'Brien, John Q Trojanowski, Virginia M-Y Lee. Science 2012
17

The many faces of α-synuclein: from structure and toxicity to therapeutic target.
Hilal A Lashuel, Cassia R Overk, Abid Oueslati, Eliezer Masliah. Nat Rev Neurosci 2013
830
16

Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology.
Alexander Zimprich, Saskia Biskup, Petra Leitner, Peter Lichtner, Matthew Farrer, Sarah Lincoln, Jennifer Kachergus, Mary Hulihan, Ryan J Uitti, Donald B Calne,[...]. Neuron 2004
15

The precursor protein of non-A beta component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system.
A Iwai, E Masliah, M Yoshimoto, N Ge, L Flanagan, H A de Silva, A Kittel, T Saitoh. Neuron 1995
994
15


Exogenous α-synuclein fibrils induce Lewy body pathology leading to synaptic dysfunction and neuron death.
Laura A Volpicelli-Daley, Kelvin C Luk, Tapan P Patel, Selcuk A Tanik, Dawn M Riddle, Anna Stieber, David F Meaney, John Q Trojanowski, Virginia M-Y Lee. Neuron 2011
828
15

α-Synuclein assembles into higher-order multimers upon membrane binding to promote SNARE complex formation.
Jacqueline Burré, Manu Sharma, Thomas C Südhof. Proc Natl Acad Sci U S A 2014
249
14

Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease.
K Uéda, H Fukushima, E Masliah, Y Xia, A Iwai, M Yoshimoto, D A Otero, J Kondo, Y Ihara, T Saitoh. Proc Natl Acad Sci U S A 1993
14

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism.
T Kitada, S Asakawa, N Hattori, H Matsumine, Y Yamamura, S Minoshima, M Yokochi, Y Mizuno, N Shimizu. Nature 1998
14

Cryo-EM structure of alpha-synuclein fibrils.
Ricardo Guerrero-Ferreira, Nicholas Mi Taylor, Daniel Mona, Philippe Ringler, Matthias E Lauer, Roland Riek, Markus Britschgi, Henning Stahlberg. Elife 2018
218
14

Genome-wide association study reveals genetic risk underlying Parkinson's disease.
Javier Simón-Sánchez, Claudia Schulte, Jose M Bras, Manu Sharma, J Raphael Gibbs, Daniela Berg, Coro Paisan-Ruiz, Peter Lichtner, Sonja W Scholz, Dena G Hernandez,[...]. Nat Genet 2009
13

Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy.
Ana Maria Cuervo, Leonidas Stefanis, Ross Fredenburg, Peter T Lansbury, David Sulzer. Science 2004
13

Parkinson disease.
Werner Poewe, Klaus Seppi, Caroline M Tanner, Glenda M Halliday, Patrik Brundin, Jens Volkmann, Anette-Eleonore Schrag, Anthony E Lang. Nat Rev Dis Primers 2017
13

Genetics of Parkinson's disease.
Christine Klein, Ana Westenberger. Cold Spring Harb Perspect Med 2012
593
13

In vivo demonstration that alpha-synuclein oligomers are toxic.
Beate Winner, Roberto Jappelli, Samir K Maji, Paula A Desplats, Leah Boyer, Stefan Aigner, Claudia Hetzer, Thomas Loher, Marçal Vilar, Silvia Campioni,[...]. Proc Natl Acad Sci U S A 2011
881
13

NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded.
P H Weinreb, W Zhen, A W Poon, K A Conway, P T Lansbury. Biochemistry 1996
13

Increased expression of alpha-synuclein reduces neurotransmitter release by inhibiting synaptic vesicle reclustering after endocytosis.
Venu M Nemani, Wei Lu, Victoria Berge, Ken Nakamura, Bibiana Onoa, Michael K Lee, Farrukh A Chaudhry, Roger A Nicoll, Robert H Edwards. Neuron 2010
655
12

Identification of two distinct synucleins from human brain.
R Jakes, M G Spillantini, M Goedert. FEBS Lett 1994
798
12

Causal relation between alpha-synuclein gene duplication and familial Parkinson's disease.
P Ibáñez, A-M Bonnet, B Débarges, E Lohmann, F Tison, P Pollak, Y Agid, A Dürr, A Brice. Lancet 2004
749
12

The novel Parkinson's disease linked mutation G51D attenuates in vitro aggregation and membrane binding of α-synuclein, and enhances its secretion and nuclear localization in cells.
Mohamed-Bilal Fares, Nadine Ait-Bouziad, Igor Dikiy, Martial K Mbefo, Ana Jovičić, Aoife Kiely, Janice L Holton, Seung-Jae Lee, Aaron D Gitler, David Eliezer,[...]. Hum Mol Genet 2014
137
12

Solid-state NMR structure of a pathogenic fibril of full-length human α-synuclein.
Marcus D Tuttle, Gemma Comellas, Andrew J Nieuwkoop, Dustin J Covell, Deborah A Berthold, Kathryn D Kloepper, Joseph M Courtney, Jae K Kim, Alexander M Barclay, Amy Kendall,[...]. Nat Struct Mol Biol 2016
471
12

Structural and functional characterization of two alpha-synuclein strains.
Luc Bousset, Laura Pieri, Gemma Ruiz-Arlandis, Julia Gath, Poul Henning Jensen, Birgit Habenstein, Karine Madiona, Vincent Olieric, Anja Böckmann, Beat H Meier,[...]. Nat Commun 2013
478
12


Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein.
Benoit I Giasson, John E Duda, Shawn M Quinn, Bin Zhang, John Q Trojanowski, Virginia M-Y Lee. Neuron 2002
817
12

Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice.
Kelvin C Luk, Victoria M Kehm, Bin Zhang, Patrick O'Brien, John Q Trojanowski, Virginia M Y Lee. J Exp Med 2012
659
12

Oxidative damage linked to neurodegeneration by selective alpha-synuclein nitration in synucleinopathy lesions.
B I Giasson, J E Duda, I V Murray, Q Chen, J M Souza, H I Hurtig, H Ischiropoulos, J Q Trojanowski, V M Lee. Science 2000
12


Functional cooperation of α-synuclein and VAMP2 in synaptic vesicle recycling.
Jichao Sun, Lina Wang, Huan Bao, Sanjay Premi, Utpal Das, Edwin R Chapman, Subhojit Roy. Proc Natl Acad Sci U S A 2019
48
22

Synucleins regulate the kinetics of synaptic vesicle endocytosis.
Karina J Vargas, Sachin Makani, Taylor Davis, Christopher H Westphal, Pablo E Castillo, Sreeganga S Chandra. J Neurosci 2014
154
11

Cell-produced alpha-synuclein is secreted in a calcium-dependent manner by exosomes and impacts neuronal survival.
Evangelia Emmanouilidou, Katerina Melachroinou, Theodoros Roumeliotis, Spiros D Garbis, Maria Ntzouni, Lukas H Margaritis, Leonidas Stefanis, Kostas Vekrellis. J Neurosci 2010
700
11

Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies.
M Baba, S Nakajo, P H Tu, T Tomita, K Nakaya, V M Lee, J Q Trojanowski, T Iwatsubo. Am J Pathol 1998
11

Phosphorylation of Ser-129 is the dominant pathological modification of alpha-synuclein in familial and sporadic Lewy body disease.
John P Anderson, Donald E Walker, Jason M Goldstein, Rian de Laat, Kelly Banducci, Russell J Caccavello, Robin Barbour, Jiping Huang, Kristin Kling, Michael Lee,[...]. J Biol Chem 2006
777
11


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.