B van Steensel, A Smogorzewska, T de Lange. Cell 1998
Times Cited: 1153
Times Cited: 1153
Times Cited
Times Co-cited
Similarity
Shelterin: the protein complex that shapes and safeguards human telomeres.
Titia de Lange. Genes Dev 2005
Titia de Lange. Genes Dev 2005
43
Mammalian telomeres end in a large duplex loop.
J D Griffith, L Comeau, S Rosenfield, R M Stansel, A Bianchi, H Moss, T de Lange. Cell 1999
J D Griffith, L Comeau, S Rosenfield, R M Stansel, A Bianchi, H Moss, T de Lange. Cell 1999
33
Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1.
Eros Lazzerini Denchi, Titia de Lange. Nature 2007
Eros Lazzerini Denchi, Titia de Lange. Nature 2007
29
p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2.
J Karlseder, D Broccoli, Y Dai, S Hardy, T de Lange. Science 1999
J Karlseder, D Broccoli, Y Dai, S Hardy, T de Lange. Science 1999
25
Super-resolution fluorescence imaging of telomeres reveals TRF2-dependent T-loop formation.
Ylli Doksani, John Y Wu, Titia de Lange, Xiaowei Zhuang. Cell 2013
Ylli Doksani, John Y Wu, Titia de Lange, Xiaowei Zhuang. Cell 2013
25
Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication.
Agnel Sfeir, Settapong T Kosiyatrakul, Dirk Hockemeyer, Sheila L MacRae, Jan Karlseder, Carl L Schildkraut, Titia de Lange. Cell 2009
Agnel Sfeir, Settapong T Kosiyatrakul, Dirk Hockemeyer, Sheila L MacRae, Jan Karlseder, Carl L Schildkraut, Titia de Lange. Cell 2009
23
Telomeres shorten during ageing of human fibroblasts.
C B Harley, A B Futcher, C W Greider. Nature 1990
C B Harley, A B Futcher, C W Greider. Nature 1990
21
DNA damage foci at dysfunctional telomeres.
Hiroyuki Takai, Agata Smogorzewska, Titia de Lange. Curr Biol 2003
Hiroyuki Takai, Agata Smogorzewska, Titia de Lange. Curr Biol 2003
21
21
Removal of shelterin reveals the telomere end-protection problem.
Agnel Sfeir, Titia de Lange. Science 2012
Agnel Sfeir, Titia de Lange. Science 2012
21
Control of telomere length by the human telomeric protein TRF1.
B van Steensel, T de Lange. Nature 1997
B van Steensel, T de Lange. Nature 1997
20
Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2.
D Broccoli, A Smogorzewska, L Chong, T de Lange. Nat Genet 1997
D Broccoli, A Smogorzewska, L Chong, T de Lange. Nat Genet 1997
19
Telomeres in cancer: tumour suppression and genome instability.
John Maciejowski, Titia de Lange. Nat Rev Mol Cell Biol 2017
John Maciejowski, Titia de Lange. Nat Rev Mol Cell Biol 2017
17
Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends.
Claus M Azzalin, Patrick Reichenbach, Lela Khoriauli, Elena Giulotto, Joachim Lingner. Science 2007
Claus M Azzalin, Patrick Reichenbach, Lela Khoriauli, Elena Giulotto, Joachim Lingner. Science 2007
17
Specific association of human telomerase activity with immortal cells and cancer.
N W Kim, M A Piatyszek, K R Prowse, C B Harley, M D West, P L Ho, G M Coviello, W E Wright, S L Weinrich, J W Shay. Science 1994
N W Kim, M A Piatyszek, K R Prowse, C B Harley, M D West, P L Ho, G M Coviello, W E Wright, S L Weinrich, J W Shay. Science 1994
17
Identification of a specific telomere terminal transferase activity in Tetrahymena extracts.
C W Greider, E H Blackburn. Cell 1985
C W Greider, E H Blackburn. Cell 1985
17
Pot1, the putative telomere end-binding protein in fission yeast and humans.
P Baumann, T R Cech. Science 2001
P Baumann, T R Cech. Science 2001
17
Control of human telomere length by TRF1 and TRF2.
A Smogorzewska, B van Steensel, A Bianchi, S Oelmann, M R Schaefer, G Schnapp, T de Lange. Mol Cell Biol 2000
A Smogorzewska, B van Steensel, A Bianchi, S Oelmann, M R Schaefer, G Schnapp, T de Lange. Mol Cell Biol 2000
17
A DNA damage checkpoint response in telomere-initiated senescence.
Fabrizio d'Adda di Fagagna, Philip M Reaper, Lorena Clay-Farrace, Heike Fiegler, Philippa Carr, Thomas Von Zglinicki, Gabriele Saretzki, Nigel P Carter, Stephen P Jackson. Nature 2003
Fabrizio d'Adda di Fagagna, Philip M Reaper, Lorena Clay-Farrace, Heike Fiegler, Philippa Carr, Thomas Von Zglinicki, Gabriele Saretzki, Nigel P Carter, Stephen P Jackson. Nature 2003
16
A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes.
R K Moyzis, J M Buckingham, L S Cram, M Dani, L L Deaven, M D Jones, J Meyne, R L Ratliff, J R Wu. Proc Natl Acad Sci U S A 1988
R K Moyzis, J M Buckingham, L S Cram, M Dani, L L Deaven, M D Jones, J Meyne, R L Ratliff, J R Wu. Proc Natl Acad Sci U S A 1988
14
Extension of life-span by introduction of telomerase into normal human cells.
A G Bodnar, M Ouellette, M Frolkis, S E Holt, C P Chiu, G B Morin, C B Harley, J W Shay, S Lichtsteiner, W E Wright. Science 1998
A G Bodnar, M Ouellette, M Frolkis, S E Holt, C P Chiu, G B Morin, C B Harley, J W Shay, S Lichtsteiner, W E Wright. Science 1998
14
Chromothripsis and Kataegis Induced by Telomere Crisis.
John Maciejowski, Yilong Li, Nazario Bosco, Peter J Campbell, Titia de Lange. Cell 2015
John Maciejowski, Yilong Li, Nazario Bosco, Peter J Campbell, Titia de Lange. Cell 2015
14
A two-step mechanism for TRF2-mediated chromosome-end protection.
Keiji Okamoto, Cristina Bartocci, Iliana Ouzounov, Jolene K Diedrich, John R Yates, Eros Lazzerini Denchi. Nature 2013
Keiji Okamoto, Cristina Bartocci, Iliana Ouzounov, Jolene K Diedrich, John R Yates, Eros Lazzerini Denchi. Nature 2013
14
DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion.
Giulia B Celli, Titia de Lange. Nat Cell Biol 2005
Giulia B Celli, Titia de Lange. Nat Cell Biol 2005
14
Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines.
T M Bryan, A Englezou, L Dalla-Pozza, M A Dunham, R R Reddel. Nat Med 1997
T M Bryan, A Englezou, L Dalla-Pozza, M A Dunham, R R Reddel. Nat Med 1997
13
Telomeric localization of TRF2, a novel human telobox protein.
T Bilaud, C Brun, K Ancelin, C E Koering, T Laroche, E Gilson. Nat Genet 1997
T Bilaud, C Brun, K Ancelin, C E Koering, T Laroche, E Gilson. Nat Genet 1997
13
POT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complex.
Jeffrey Zheng-Sheng Ye, Dirk Hockemeyer, Andrew N Krutchinsky, Diego Loayza, Sarah M Hooper, Brian T Chait, Titia de Lange. Genes Dev 2004
Jeffrey Zheng-Sheng Ye, Dirk Hockemeyer, Andrew N Krutchinsky, Diego Loayza, Sarah M Hooper, Brian T Chait, Titia de Lange. Genes Dev 2004
12
Break-induced telomere synthesis underlies alternative telomere maintenance.
Robert L Dilley, Priyanka Verma, Nam Woo Cho, Harrison D Winters, Anne R Wondisford, Roger A Greenberg. Nature 2016
Robert L Dilley, Priyanka Verma, Nam Woo Cho, Harrison D Winters, Anne R Wondisford, Roger A Greenberg. Nature 2016
12
T-loop assembly in vitro involves binding of TRF2 near the 3' telomeric overhang.
R M Stansel, T de Lange, J D Griffith. EMBO J 2001
R M Stansel, T de Lange, J D Griffith. EMBO J 2001
12
Telomeric 3' overhangs derive from resection by Exo1 and Apollo and fill-in by POT1b-associated CST.
Peng Wu, Hiroyuki Takai, Titia de Lange. Cell 2012
Peng Wu, Hiroyuki Takai, Titia de Lange. Cell 2012
12
The telomeric protein TRF2 binds the ATM kinase and can inhibit the ATM-dependent DNA damage response.
Jan Karlseder, Kristina Hoke, Olga K Mirzoeva, Christopher Bakkenist, Michael B Kastan, John H J Petrini, Titia de Lange. PLoS Biol 2004
Jan Karlseder, Kristina Hoke, Olga K Mirzoeva, Christopher Bakkenist, Michael B Kastan, John H J Petrini, Titia de Lange. PLoS Biol 2004
12
PTOP interacts with POT1 and regulates its localization to telomeres.
Dan Liu, Amin Safari, Matthew S O'Connor, Doug W Chan, Andrew Laegeler, Jun Qin, Zhou Songyang. Nat Cell Biol 2004
Dan Liu, Amin Safari, Matthew S O'Connor, Doug W Chan, Andrew Laegeler, Jun Qin, Zhou Songyang. Nat Cell Biol 2004
11
TIN2, a new regulator of telomere length in human cells.
S H Kim, P Kaminker, J Campisi. Nat Genet 1999
S H Kim, P Kaminker, J Campisi. Nat Genet 1999
11
Developmentally regulated transcription of mammalian telomeres by DNA-dependent RNA polymerase II.
Stefan Schoeftner, Maria A Blasco. Nat Cell Biol 2008
Stefan Schoeftner, Maria A Blasco. Nat Cell Biol 2008
11
DNA ligase IV-dependent NHEJ of deprotected mammalian telomeres in G1 and G2.
Agata Smogorzewska, Jan Karlseder, Heidi Holtgreve-Grez, Anna Jauch, Titia de Lange. Curr Biol 2002
Agata Smogorzewska, Jan Karlseder, Heidi Holtgreve-Grez, Anna Jauch, Titia de Lange. Curr Biol 2002
11
TIN2 binds TRF1 and TRF2 simultaneously and stabilizes the TRF2 complex on telomeres.
Jeffrey Zheng-Sheng Ye, Jill R Donigian, Megan van Overbeek, Diego Loayza, Yan Luo, Andrew N Krutchinsky, Brian T Chait, Titia de Lange. J Biol Chem 2004
Jeffrey Zheng-Sheng Ye, Jill R Donigian, Megan van Overbeek, Diego Loayza, Yan Luo, Andrew N Krutchinsky, Brian T Chait, Titia de Lange. J Biol Chem 2004
11
The telomere deprotection response is functionally distinct from the genomic DNA damage response.
Anthony J Cesare, Makoto T Hayashi, Laure Crabbe, Jan Karlseder. Mol Cell 2013
Anthony J Cesare, Makoto T Hayashi, Laure Crabbe, Jan Karlseder. Mol Cell 2013
11
Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening.
V L Makarov, Y Hirose, J P Langmore. Cell 1997
V L Makarov, Y Hirose, J P Langmore. Cell 1997
10
Cell death during crisis is mediated by mitotic telomere deprotection.
Makoto T Hayashi, Anthony J Cesare, Teresa Rivera, Jan Karlseder. Nature 2015
Makoto T Hayashi, Anthony J Cesare, Teresa Rivera, Jan Karlseder. Nature 2015
15
Identification of human Rap1: implications for telomere evolution.
B Li, S Oestreich, T de Lange. Cell 2000
B Li, S Oestreich, T de Lange. Cell 2000
10
RTEL1 dismantles T loops and counteracts telomeric G4-DNA to maintain telomere integrity.
Jean-Baptiste Vannier, Visnja Pavicic-Kaltenbrunner, Mark I R Petalcorin, Hao Ding, Simon J Boulton. Cell 2012
Jean-Baptiste Vannier, Visnja Pavicic-Kaltenbrunner, Mark I R Petalcorin, Hao Ding, Simon J Boulton. Cell 2012
10
TRF2 recruits RTEL1 to telomeres in S phase to promote t-loop unwinding.
Grzegorz Sarek, Jean-Baptiste Vannier, Stephanie Panier, John H J Petrini, Simon J Boulton. Mol Cell 2015
Grzegorz Sarek, Jean-Baptiste Vannier, Stephanie Panier, John H J Petrini, Simon J Boulton. Mol Cell 2015
11
The function of classical and alternative non-homologous end-joining pathways in the fusion of dysfunctional telomeres.
Rekha Rai, Hong Zheng, Hua He, Ying Luo, Asha Multani, Phillip B Carpenter, Sandy Chang. EMBO J 2010
Rekha Rai, Hong Zheng, Hua He, Ying Luo, Asha Multani, Phillip B Carpenter, Sandy Chang. EMBO J 2010
10
The POT1-TPP1 telomere complex is a telomerase processivity factor.
Feng Wang, Elaine R Podell, Arthur J Zaug, Yuting Yang, Paul Baciu, Thomas R Cech, Ming Lei. Nature 2007
Feng Wang, Elaine R Podell, Arthur J Zaug, Yuting Yang, Paul Baciu, Thomas R Cech, Ming Lei. Nature 2007
10
A topological mechanism for TRF2-enhanced strand invasion.
Simon Amiard, Michel Doudeau, Sébastien Pinte, Anaïs Poulet, Christelle Lenain, Cendrine Faivre-Moskalenko, Dimitar Angelov, Nele Hug, Alessandro Vindigni, Philippe Bouvet,[...]. Nat Struct Mol Biol 2007
Simon Amiard, Michel Doudeau, Sébastien Pinte, Anaïs Poulet, Christelle Lenain, Cendrine Faivre-Moskalenko, Dimitar Angelov, Nele Hug, Alessandro Vindigni, Philippe Bouvet,[...]. Nat Struct Mol Biol 2007
10
TRF2-RAP1 is required to protect telomeres from engaging in homologous recombination-mediated deletions and fusions.
Rekha Rai, Yong Chen, Ming Lei, Sandy Chang. Nat Commun 2016
Rekha Rai, Yong Chen, Ming Lei, Sandy Chang. Nat Commun 2016
15
A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis.
C W Greider, E H Blackburn. Nature 1989
C W Greider, E H Blackburn. Nature 1989
10
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.