A citation-based method for searching scientific literature

F M Matschinsky, B Glaser, M A Magnuson. Diabetes 1998
Times Cited: 249







List of co-cited articles
609 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Allosteric activators of glucokinase: potential role in diabetes therapy.
Joseph Grimsby, Ramakanth Sarabu, Wendy L Corbett, Nancy-Ellen Haynes, Fred T Bizzarro, John W Coffey, Kevin R Guertin, Darryl W Hilliard, Robert F Kester, Paige E Mahaney,[...]. Science 2003
361
30


Structural basis for allosteric regulation of the monomeric allosteric enzyme human glucokinase.
Kenji Kamata, Morihiro Mitsuya, Teruyuki Nishimura, Jun-Ichi Eiki, Yasufumi Nagata. Structure 2004
329
21


Effects of MK-0941, a novel glucokinase activator, on glycemic control in insulin-treated patients with type 2 diabetes.
Gary E Meininger, Russell Scott, Maria Alba, Yue Shentu, Edmund Luo, Himal Amin, Michael J Davies, Keith D Kaufman, Barry J Goldstein. Diabetes Care 2011
123
16

Familial hyperinsulinism caused by an activating glucokinase mutation.
B Glaser, P Kesavan, M Heyman, E Davis, A Cuesta, A Buchs, C A Stanley, P S Thornton, M A Permutt, F M Matschinsky,[...]. N Engl J Med 1998
406
15

Glucokinase activators in diabetes management.
Matthew Coghlan, Brendan Leighton. Expert Opin Investig Drugs 2008
80
18

Discovery of (S)-6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid as a hepatoselective glucokinase activator clinical candidate for treating type 2 diabetes mellitus.
Jeffrey A Pfefferkorn, Angel Guzman-Perez, John Litchfield, Robert Aiello, Judith L Treadway, John Pettersen, Martha L Minich, Kevin J Filipski, Christopher S Jones, Meihua Tu,[...]. J Med Chem 2012
80
17



Investigation of functionally liver selective glucokinase activators for the treatment of type 2 diabetes.
Gregory R Bebernitz, Valerie Beaulieu, Bethany A Dale, Richard Deacon, Alokesh Duttaroy, Jiaping Gao, Melissa S Grondine, Ramesh C Gupta, Mesut Kakmak, Michael Kavana,[...]. J Med Chem 2009
59
20

Molecular physiology of mammalian glucokinase.
P B Iynedjian. Cell Mol Life Sci 2009
203
11

A novel glucokinase activator modulates pancreatic islet and hepatocyte function.
Alexander M Efanov, David G Barrett, Martin B Brenner, Stephen L Briggs, Annie Delaunois, Jim D Durbin, Ulrich Giese, Haihong Guo, Mark Radloff, Gema Sanz Gil,[...]. Endocrinology 2005
96
10

Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes.
Alexandra E Butler, Juliette Janson, Susan Bonner-Weir, Robert Ritzel, Robert A Rizza, Peter C Butler. Diabetes 2003
10

Glucokinase activator PSN-GK1 displays enhanced antihyperglycaemic and insulinotropic actions.
M C T Fyfe, J R White, A Taylor, R Chatfield, E Wargent, R L Printz, T Sulpice, J G McCormack, M J Procter, C Reynet,[...]. Diabetologia 2007
66
15

Update on mutations in glucokinase (GCK), which cause maturity-onset diabetes of the young, permanent neonatal diabetes, and hyperinsulinemic hypoglycemia.
Kara K Osbak, Kevin Colclough, Cecile Saint-Martin, Nicola L Beer, Christine Bellanné-Chantelot, Sian Ellard, Anna L Gloyn. Hum Mutat 2009
257
10

Novel glucokinase activators: a patent review (2008 - 2010).
Ramakanth Sarabu, Steven J Berthel, Robert F Kester, Jefferson W Tilley. Expert Opin Ther Pat 2011
37
27

An allosteric activator of glucokinase impairs the interaction of glucokinase and glucokinase regulatory protein and regulates glucose metabolism.
Mayumi Futamura, Hideka Hosaka, Akito Kadotani, Hiroko Shimazaki, Kaori Sasaki, Sumika Ohyama, Teruyuki Nishimura, Jun-Ichi Eiki, Yasufumi Nagata. J Biol Chem 2006
74
12

The second activating glucokinase mutation (A456V): implications for glucose homeostasis and diabetes therapy.
Henrik B T Christesen, Bendt B Jacobsen, Stella Odili, Carol Buettger, Antonio Cuesta-Munoz, Torben Hansen, Klaus Brusgaard, Ornella Massa, Mark A Magnuson, Chiyo Shiota,[...]. Diabetes 2002
112
9

SAR, pharmacokinetics, safety, and efficacy of glucokinase activating 2-(4-sulfonylphenyl)-N-thiazol-2-ylacetamides: discovery of PSN-GK1.
Lisa S Bertram, Daniel Black, Paul H Briner, Rosemary Chatfield, Andrew Cooke, Matthew C T Fyfe, P John Murray, Frédéric Naud, Masao Nawano, Martin J Procter,[...]. J Med Chem 2008
32
28

Familial hyperglycemia due to mutations in glucokinase. Definition of a subtype of diabetes mellitus.
P Froguel, H Zouali, N Vionnet, G Velho, M Vaxillaire, F Sun, S Lesage, M Stoffel, J Takeda, P Passa. N Engl J Med 1993
619
9


The network of glucokinase-expressing cells in glucose homeostasis and the potential of glucokinase activators for diabetes therapy.
Franz M Matschinsky, Mark A Magnuson, Dorothy Zelent, Tom L Jetton, Nicolai Doliba, Yi Han, Rebecca Taub, Joseph Grimsby. Diabetes 2006
177
8

Identification of 14 new glucokinase mutations and description of the clinical profile of 42 MODY-2 families.
G Velho, H Blanché, M Vaxillaire, C Bellanné-Chantelot, V C Pardini, J Timsit, P Passa, I Deschamps, J J Robert, I T Weber,[...]. Diabetologia 1997
187
8


Piragliatin (RO4389620), a novel glucokinase activator, lowers plasma glucose both in the postabsorptive state and after a glucose challenge in patients with type 2 diabetes mellitus: a mechanistic study.
Riccardo C Bonadonna, Tim Heise, Christophe Arbet-Engels, Christoph Kapitza, Angelo Avogaro, Joe Grimsby, Jay Zhi, Joseph F Grippo, Raffaella Balena. J Clin Endocrinol Metab 2010
97
8

Stimulation of hepatocyte glucose metabolism by novel small molecule glucokinase activators.
Katy J Brocklehurst, Victoria A Payne, Rick A Davies, Debra Carroll, Helen L Vertigan, Heather J Wightman, Susan Aiston, Ian D Waddell, Brendan Leighton, Matthew P Coghlan,[...]. Diabetes 2004
115
7

Predictive blood glucose lowering efficacy by Glucokinase activators in high fat fed female Zucker rats.
G J Coope, A M Atkinson, C Allott, D McKerrecher, C Johnstone, K G Pike, P C Holme, H Vertigan, D Gill, M P Coghlan,[...]. Br J Pharmacol 2006
56
12


Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase.
C Postic, M Shiota, K D Niswender, T L Jetton, Y Chen, J M Moates, K D Shelton, J Lindner, A D Cherrington, M A Magnuson. J Biol Chem 1999
912
7

Discovery, structure-activity relationships, pharmacokinetics, and efficacy of glucokinase activator (2R)-3-cyclopentyl-2-(4-methanesulfonylphenyl)-N-thiazol-2-yl-propionamide (RO0281675).
Nancy-Ellen Haynes, Wendy L Corbett, Fred T Bizzarro, Kevin R Guertin, Darryl W Hilliard, George W Holland, Robert F Kester, Paige E Mahaney, Lida Qi, Cheryl L Spence,[...]. J Med Chem 2010
31
22



Antidiabetic effects of glucokinase regulatory protein small-molecule disruptors.
David J Lloyd, David J St Jean, Robert J M Kurzeja, Robert C Wahl, Klaus Michelsen, Rod Cupples, Michelle Chen, John Wu, Glenn Sivits, Joan Helmering,[...]. Nature 2013
62
11

Glucose-dependent modulation of insulin secretion and intracellular calcium ions by GKA50, a glucokinase activator.
Daniel Johnson, Ruth M Shepherd, Debra Gill, Tracy Gorman, David M Smith, Mark J Dunne. Diabetes 2007
63
9

Targeting glucokinase activation for the treatment of type 2 diabetes--a status review.
Ramakanth Sarabu, Joseph Grimsby. Curr Opin Drug Discov Devel 2005
54
11

Glucose-induced conformational changes in glucokinase mediate allosteric regulation: transient kinetic analysis.
Vladi V Heredia, Jim Thomson, David Nettleton, Shaoxian Sun. Biochemistry 2006
68
8

Insights into the biochemical and genetic basis of glucokinase activation from naturally occurring hypoglycemia mutations.
Anna L Gloyn, Kees Noordam, Michèl A A P Willemsen, Sian Ellard, Wayne W K Lam, Ian W Campbell, Paula Midgley, Chyio Shiota, Carol Buettger, Mark A Magnuson,[...]. Diabetes 2003
111
6


Design of a potent, soluble glucokinase activator with excellent in vivo efficacy.
Darren McKerrecher, Joanne V Allen, Peter W R Caulkett, Craig S Donald, Mark L Fenwick, Emma Grange, Keith M Johnson, Craig Johnstone, Clifford D Jones, Kurt G Pike,[...]. Bioorg Med Chem Lett 2006
57
10

Analysis of upstream glucokinase promoter activity in transgenic mice and identification of glucokinase in rare neuroendocrine cells in the brain and gut.
T L Jetton, Y Liang, C C Pettepher, E C Zimmerman, F G Cox, K Horvath, F M Matschinsky, M A Magnuson. J Biol Chem 1994
243
6

Discovery of novel 3,6-disubstituted 2-pyridinecarboxamide derivatives as GK activators.
Morihiro Mitsuya, Kenji Kamata, Makoto Bamba, Hitomi Watanabe, Yasuhiro Sasaki, Kaori Sasaki, Sumika Ohyama, Hideka Hosaka, Yasufumi Nagata, Jun-ichi Eiki,[...]. Bioorg Med Chem Lett 2009
29
20


Insulin granule dynamics in pancreatic beta cells.
P Rorsman, E Renström. Diabetologia 2003
504
6

Glucokinase is the likely mediator of glucosensing in both glucose-excited and glucose-inhibited central neurons.
Ambrose A Dunn-Meynell, Vanessa H Routh, Ling Kang, Larry Gaspers, Barry E Levin. Diabetes 2002
236
6

Mechanisms linking obesity to insulin resistance and type 2 diabetes.
Steven E Kahn, Rebecca L Hull, Kristina M Utzschneider. Nature 2006
6


Glucokinase and IRS-2 are required for compensatory beta cell hyperplasia in response to high-fat diet-induced insulin resistance.
Yasuo Terauchi, Iseki Takamoto, Naoto Kubota, Junji Matsui, Ryo Suzuki, Kajuro Komeda, Akemi Hara, Yukiyasu Toyoda, Ichitomo Miwa, Shinichi Aizawa,[...]. J Clin Invest 2007
250
5


Islet beta cell failure in type 2 diabetes.
Marc Prentki, Christopher J Nolan. J Clin Invest 2006
5


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.