A citation-based method for searching scientific literature

A Gallimore, A Glithero, A Godkin, A C Tissot, A Plückthun, T Elliott, H Hengartner, R Zinkernagel. J Exp Med 1998
Times Cited: 578







List of co-cited articles
1271 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Viral immune evasion due to persistence of activated T cells without effector function.
A J Zajac, J N Blattman, K Murali-Krishna, D J Sourdive, M Suresh, J D Altman, R Ahmed. J Exp Med 1998
80

Molecular and cellular insights into T cell exhaustion.
E John Wherry, Makoto Kurachi. Nat Rev Immunol 2015
43

Restoring function in exhausted CD8 T cells during chronic viral infection.
Daniel L Barber, E John Wherry, David Masopust, Baogong Zhu, James P Allison, Arlene H Sharpe, Gordon J Freeman, Rafi Ahmed. Nature 2006
43

Molecular signature of CD8+ T cell exhaustion during chronic viral infection.
E John Wherry, Sang-Jun Ha, Susan M Kaech, W Nicholas Haining, Surojit Sarkar, Vandana Kalia, Shruti Subramaniam, Joseph N Blattman, Daniel L Barber, Rafi Ahmed. Immunity 2007
38

CD8 T Cell Exhaustion During Chronic Viral Infection and Cancer.
Laura M McLane, Mohamed S Abdel-Hakeem, E John Wherry. Annu Rev Immunol 2019
516
36

Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy.
Se Jin Im, Masao Hashimoto, Michael Y Gerner, Junghwa Lee, Haydn T Kissick, Matheus C Burger, Qiang Shan, J Scott Hale, Judong Lee, Tahseen H Nasti,[...]. Nature 2016
812
35

Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment.
E John Wherry, Joseph N Blattman, Kaja Murali-Krishna, Robbert van der Most, Rafi Ahmed. J Virol 2003
33

Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade.
Kristen E Pauken, Morgan A Sammons, Pamela M Odorizzi, Sasikanth Manne, Jernej Godec, Omar Khan, Adam M Drake, Zeyu Chen, Debattama R Sen, Makoto Kurachi,[...]. Science 2016
600
32

Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection.
Shawn D Blackburn, Haina Shin, W Nicholas Haining, Tao Zou, Creg J Workman, Antonio Polley, Michael R Betts, Gordon J Freeman, Dario A A Vignali, E John Wherry. Nat Immunol 2009
31


T cell exhaustion.
E John Wherry. Nat Immunol 2011
31

TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion.
Omar Khan, Josephine R Giles, Sierra McDonald, Sasikanth Manne, Shin Foong Ngiow, Kunal P Patel, Michael T Werner, Alexander C Huang, Katherine A Alexander, Jennifer E Wu,[...]. Nature 2019
445
31

Progenitor and terminal subsets of CD8+ T cells cooperate to contain chronic viral infection.
Michael A Paley, Daniela C Kroy, Pamela M Odorizzi, Jonathan B Johnnidis, Douglas V Dolfi, Burton E Barnett, Elizabeth K Bikoff, Elizabeth J Robertson, Georg M Lauer, Steven L Reiner,[...]. Science 2012
534
30

The epigenetic landscape of T cell exhaustion.
Debattama R Sen, James Kaminski, R Anthony Barnitz, Makoto Kurachi, Ulrike Gerdemann, Kathleen B Yates, Hsiao-Wei Tsao, Jernej Godec, Martin W LaFleur, Flavian D Brown,[...]. Science 2016
471
29

T Cell Factor 1-Expressing Memory-like CD8(+) T Cells Sustain the Immune Response to Chronic Viral Infections.
Daniel T Utzschneider, Mélanie Charmoy, Vijaykumar Chennupati, Laurène Pousse, Daniela Pais Ferreira, Sandra Calderon-Copete, Maxime Danilo, Francesca Alfei, Maike Hofmann, Dominik Wieland,[...]. Immunity 2016
397
28

TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection.
Francesca Alfei, Kristiyan Kanev, Maike Hofmann, Ming Wu, Hazem E Ghoneim, Patrick Roelli, Daniel T Utzschneider, Madlaina von Hoesslin, Jolie G Cullen, Yiping Fan,[...]. Nature 2019
302
25

TOX is a critical regulator of tumour-specific T cell differentiation.
Andrew C Scott, Friederike Dündar, Paul Zumbo, Smita S Chandran, Christopher A Klebanoff, Mojdeh Shakiba, Prerak Trivedi, Laura Menocal, Heather Appleby, Steven Camara,[...]. Nature 2019
355
25

Network analysis reveals centrally connected genes and pathways involved in CD8+ T cell exhaustion versus memory.
Travis A Doering, Alison Crawford, Jill M Angelosanto, Michael A Paley, Carly G Ziegler, E John Wherry. Immunity 2012
320
24

Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade.
Brian C Miller, Debattama R Sen, Rose Al Abosy, Kevin Bi, Yamini V Virkud, Martin W LaFleur, Kathleen B Yates, Ana Lako, Kristen Felt, Girish S Naik,[...]. Nat Immunol 2019
512
23

TOX and TOX2 transcription factors cooperate with NR4A transcription factors to impose CD8+ T cell exhaustion.
Hyungseok Seo, Joyce Chen, Edahí González-Avalos, Daniela Samaniego-Castruita, Arundhoti Das, Yueqiang H Wang, Isaac F López-Moyado, Romain O Georges, Wade Zhang, Atsushi Onodera,[...]. Proc Natl Acad Sci U S A 2019
235
23

The transcription factor NFAT promotes exhaustion of activated CD8⁺ T cells.
Gustavo J Martinez, Renata M Pereira, Tarmo Äijö, Edward Y Kim, Francesco Marangoni, Matthew E Pipkin, Susan Togher, Vigo Heissmeyer, Yi Chen Zhang, Shane Crotty,[...]. Immunity 2015
344
22

Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma.
Moshe Sade-Feldman, Keren Yizhak, Stacey L Bjorgaard, John P Ray, Carl G de Boer, Russell W Jenkins, David J Lieb, Jonathan H Chen, Dennie T Frederick, Michal Barzily-Rokni,[...]. Cell 2018
588
20

Chromatin states define tumour-specific T cell dysfunction and reprogramming.
Mary Philip, Lauren Fairchild, Liping Sun, Ellen L Horste, Steven Camara, Mojdeh Shakiba, Andrew C Scott, Agnes Viale, Peter Lauer, Taha Merghoub,[...]. Nature 2017
399
19

The TCF1-Bcl6 axis counteracts type I interferon to repress exhaustion and maintain T cell stemness.
Tuoqi Wu, Yun Ji, E Ashley Moseman, Haifeng C Xu, Monica Manglani, Martha Kirby, Stacie M Anderson, Robin Handon, Elizabeth Kenyon, Abdel Elkahloun,[...]. Sci Immunol 2016
222
19

PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression.
Cheryl L Day, Daniel E Kaufmann, Photini Kiepiela, Julia A Brown, Eshia S Moodley, Sharon Reddy, Elizabeth W Mackey, Joseph D Miller, Alasdair J Leslie, Chantal DePierres,[...]. Nature 2006
18

Exhaustion of tumor-specific CD8⁺ T cells in metastases from melanoma patients.
Lukas Baitsch, Petra Baumgaertner, Estelle Devêvre, Sunil K Raghav, Amandine Legat, Leticia Barba, Sébastien Wieckowski, Hanifa Bouzourene, Bart Deplancke, Pedro Romero,[...]. J Clin Invest 2011
526
18

Tumor-Specific T Cell Dysfunction Is a Dynamic Antigen-Driven Differentiation Program Initiated Early during Tumorigenesis.
Andrea Schietinger, Mary Philip, Varintra E Krisnawan, Edison Y Chiu, Jeffrey J Delrow, Ryan S Basom, Peter Lauer, Dirk G Brockstedt, Sue E Knoblaugh, Günter J Hämmerling,[...]. Immunity 2016
304
18

Bioenergetic Insufficiencies Due to Metabolic Alterations Regulated by the Inhibitory Receptor PD-1 Are an Early Driver of CD8(+) T Cell Exhaustion.
Bertram Bengsch, Andy L Johnson, Makoto Kurachi, Pamela M Odorizzi, Kristen E Pauken, John Attanasio, Erietta Stelekati, Laura M McLane, Michael A Paley, Greg M Delgoffe,[...]. Immunity 2016
364
17

T-cell exhaustion, co-stimulation and clinical outcome in autoimmunity and infection.
Eoin F McKinney, James C Lee, David R W Jayne, Paul A Lyons, Kenneth G C Smith. Nature 2015
350
17

Single-cell RNA-seq reveals TOX as a key regulator of CD8+ T cell persistence in chronic infection.
Chen Yao, Hong-Wei Sun, Neal E Lacey, Yun Ji, E Ashley Moseman, Han-Yu Shih, Elisabeth F Heuston, Martha Kirby, Stacie Anderson, Jun Cheng,[...]. Nat Immunol 2019
189
17

Progressive loss of memory T cell potential and commitment to exhaustion during chronic viral infection.
Jill M Angelosanto, Shawn D Blackburn, Alison Crawford, E John Wherry. J Virol 2012
160
16

Transcription Factor IRF4 Promotes CD8+ T Cell Exhaustion and Limits the Development of Memory-like T Cells during Chronic Infection.
Kevin Man, Sarah S Gabriel, Yang Liao, Renee Gloury, Simon Preston, Darren C Henstridge, Marc Pellegrini, Dietmar Zehn, Friederike Berberich-Siebelt, Mark A Febbraio,[...]. Immunity 2017
170
16

T cells maintain an exhausted phenotype after antigen withdrawal and population reexpansion.
Daniel T Utzschneider, Amandine Legat, Silvia A Fuertes Marraco, Lucie Carrié, Immanuel Luescher, Daniel E Speiser, Dietmar Zehn. Nat Immunol 2013
172
16

Defining 'T cell exhaustion'.
Christian U Blank, W Nicholas Haining, Werner Held, Patrick G Hogan, Axel Kallies, Enrico Lugli, Rachel C Lynn, Mary Philip, Anjana Rao, Nicholas P Restifo,[...]. Nat Rev Immunol 2019
358
16

Proliferating Transitory T Cells with an Effector-like Transcriptional Signature Emerge from PD-1+ Stem-like CD8+ T Cells during Chronic Infection.
William H Hudson, Julia Gensheimer, Masao Hashimoto, Andreas Wieland, Rajesh M Valanparambil, Peng Li, Jian-Xin Lin, Bogumila T Konieczny, Se Jin Im, Gordon J Freeman,[...]. Immunity 2019
146
16

De Novo Epigenetic Programs Inhibit PD-1 Blockade-Mediated T Cell Rejuvenation.
Hazem E Ghoneim, Yiping Fan, Ardiana Moustaki, Hossam A Abdelsamed, Pradyot Dash, Pranay Dogra, Robert Carter, Walid Awad, Geoff Neale, Paul G Thomas,[...]. Cell 2017
339
15

T-cell invigoration to tumour burden ratio associated with anti-PD-1 response.
Alexander C Huang, Michael A Postow, Robert J Orlowski, Rosemarie Mick, Bertram Bengsch, Sasikanth Manne, Wei Xu, Shannon Harmon, Josephine R Giles, Brandon Wenz,[...]. Nature 2017
813
15

Selective expansion of a subset of exhausted CD8 T cells by alphaPD-L1 blockade.
Shawn D Blackburn, Haina Shin, Gordon J Freeman, E John Wherry. Proc Natl Acad Sci U S A 2008
339
15

T cell costimulatory receptor CD28 is a primary target for PD-1-mediated inhibition.
Enfu Hui, Jeanne Cheung, Jing Zhu, Xiaolei Su, Marcus J Taylor, Heidi A Wallweber, Dibyendu K Sasmal, Jun Huang, Jeong M Kim, Ira Mellman,[...]. Science 2017
725
15

Follicular CXCR5- expressing CD8(+) T cells curtail chronic viral infection.
Ran He, Shiyue Hou, Cheng Liu, Anli Zhang, Qiang Bai, Miao Han, Yu Yang, Gang Wei, Ting Shen, Xinxin Yang,[...]. Nature 2016
335
15

CD8 T Cell Exhaustion in Chronic Infection and Cancer: Opportunities for Interventions.
Masao Hashimoto, Alice O Kamphorst, Se Jin Im, Haydn T Kissick, Rathi N Pillai, Suresh S Ramalingam, Koichi Araki, Rafi Ahmed. Annu Rev Med 2018
246
15

Developmental Relationships of Four Exhausted CD8+ T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms.
Jean-Christophe Beltra, Sasikanth Manne, Mohamed S Abdel-Hakeem, Makoto Kurachi, Josephine R Giles, Zeyu Chen, Valentina Casella, Shin Foong Ngiow, Omar Khan, Yinghui Jane Huang,[...]. Immunity 2020
170
15

Rescue of exhausted CD8 T cells by PD-1-targeted therapies is CD28-dependent.
Alice O Kamphorst, Andreas Wieland, Tahseen Nasti, Shu Yang, Ruan Zhang, Daniel L Barber, Bogumila T Konieczny, Candace Z Daugherty, Lydia Koenig, Ke Yu,[...]. Science 2017
474
14

Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired.
Mojgan Ahmadzadeh, Laura A Johnson, Bianca Heemskerk, John R Wunderlich, Mark E Dudley, Donald E White, Steven A Rosenberg. Blood 2009
14

Viral antigen and extensive division maintain virus-specific CD8 T cells during chronic infection.
Haina Shin, Shawn D Blackburn, Joseph N Blattman, E John Wherry. J Exp Med 2007
198
14

Intratumoral Tcf1+PD-1+CD8+ T Cells with Stem-like Properties Promote Tumor Control in Response to Vaccination and Checkpoint Blockade Immunotherapy.
Imran Siddiqui, Karin Schaeuble, Vijaykumar Chennupati, Silvia A Fuertes Marraco, Sandra Calderon-Copete, Daniela Pais Ferreira, Santiago J Carmona, Leonardo Scarpellino, David Gfeller, Sylvain Pradervand,[...]. Immunity 2019
445
14

TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision.
Zeyu Chen, Zhicheng Ji, Shin Foong Ngiow, Sasikanth Manne, Zhangying Cai, Alexander C Huang, John Johnson, Ryan P Staupe, Bertram Bengsch, Caiyue Xu,[...]. Immunity 2019
191
14

Overcoming T cell exhaustion in infection and cancer.
Kristen E Pauken, E John Wherry. Trends Immunol 2015
578
13

The immunoreceptor TIGIT regulates antitumor and antiviral CD8(+) T cell effector function.
Robert J Johnston, Laetitia Comps-Agrar, Jason Hackney, Xin Yu, Mahrukh Huseni, Yagai Yang, Summer Park, Vincent Javinal, Henry Chiu, Bryan Irving,[...]. Cancer Cell 2014
542
13

Bystander CD8+ T cells are abundant and phenotypically distinct in human tumour infiltrates.
Yannick Simoni, Etienne Becht, Michael Fehlings, Chiew Yee Loh, Si-Lin Koo, Karen Wei Weng Teng, Joe Poh Sheng Yeong, Rahul Nahar, Tong Zhang, Hassen Kared,[...]. Nature 2018
520
13


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.