A citation-based method for searching scientific literature

J P Vonsattel, M DiFiglia. J Neuropathol Exp Neurol 1998
Times Cited: 1058







List of co-cited articles
975 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity



Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice.
L Mangiarini, K Sathasivam, M Seller, B Cozens, A Harper, C Hetherington, M Lawton, Y Trottier, H Lehrach, S W Davies,[...]. Cell 1996
23

Neuropathological classification of Huntington's disease.
J P Vonsattel, R H Myers, T J Stevens, R J Ferrante, E D Bird, E P Richardson. J Neuropathol Exp Neurol 1985
20

Huntington disease.
Gillian P Bates, Ray Dorsey, James F Gusella, Michael R Hayden, Chris Kay, Blair R Leavitt, Martha Nance, Christopher A Ross, Rachael I Scahill, Ronald Wetzel,[...]. Nat Rev Dis Primers 2015
535
17

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain.
M DiFiglia, E Sapp, K O Chase, S W Davies, G P Bates, J P Vonsattel, N Aronin. Science 1997
14

Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease.
Elizabeth J Slow, Jeremy van Raamsdonk, Daniel Rogers, Sarah H Coleman, Rona K Graham, Yu Deng, Rosemary Oh, Nagat Bissada, Sazzad M Hossain, Yu-Zhou Yang,[...]. Hum Mol Genet 2003
562
13

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation.
S W Davies, M Turmaine, B A Cozens, M DiFiglia, A H Sharp, C A Ross, E Scherzinger, E E Wanker, L Mangiarini, G P Bates. Cell 1997
12

Huntington's disease: from molecular pathogenesis to clinical treatment.
Christopher A Ross, Sarah J Tabrizi. Lancet Neurol 2011
876
12

Full-length human mutant huntingtin with a stable polyglutamine repeat can elicit progressive and selective neuropathogenesis in BACHD mice.
Michelle Gray, Dyna I Shirasaki, Carlos Cepeda, Véronique M André, Brian Wilburn, Xiao-Hong Lu, Jifang Tao, Irene Yamazaki, Shi-Hua Li, Yi E Sun,[...]. J Neurosci 2008
421
11

Neuronal targets for reducing mutant huntingtin expression to ameliorate disease in a mouse model of Huntington's disease.
Nan Wang, Michelle Gray, Xiao-Hong Lu, Jeffrey P Cantle, Sandra M Holley, Erin Greiner, Xiaofeng Gu, Dyna Shirasaki, Carlos Cepeda, Yuqing Li,[...]. Nat Med 2014
127
11

Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity.
Wenjun Song, Jin Chen, Alejandra Petrilli, Geraldine Liot, Eva Klinglmayr, Yue Zhou, Patrick Poquiz, Jonathan Tjong, Mahmoud A Pouladi, Michael R Hayden,[...]. Nat Med 2011
348
11

Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage.
Ulziibat Shirendeb, Arubala P Reddy, Maria Manczak, Marcus J Calkins, Peizhong Mao, Danilo A Tagle, P Hemachandra Reddy. Hum Mol Genet 2011
246
9

Integrated genomics and proteomics define huntingtin CAG length-dependent networks in mice.
Peter Langfelder, Jeffrey P Cantle, Doxa Chatzopoulou, Nan Wang, Fuying Gao, Ismael Al-Ramahi, Xiao-Hong Lu, Eliana Marisa Ramos, Karla El-Zein, Yining Zhao,[...]. Nat Neurosci 2016
171
9

The Biology of Huntingtin.
Frédéric Saudou, Sandrine Humbert. Neuron 2016
336
9

Comprehensive behavioral and molecular characterization of a new knock-in mouse model of Huntington's disease: zQ175.
Liliana B Menalled, Andrea E Kudwa, Sam Miller, Jon Fitzpatrick, Judy Watson-Johnson, Nicole Keating, Melinda Ruiz, Richard Mushlin, William Alosio, Kristi McConnell,[...]. PLoS One 2012
207
9

Huntington's disease.
Francis O Walker. Lancet 2007
8

Regional and cellular gene expression changes in human Huntington's disease brain.
Angela Hodges, Andrew D Strand, Aaron K Aragaki, Alexandre Kuhn, Thierry Sengstag, Gareth Hughes, Lyn A Elliston, Cathy Hartog, Darlene R Goldstein, Doris Thu,[...]. Hum Mol Genet 2006
515
8

Mutant huntingtin's interaction with mitochondrial protein Drp1 impairs mitochondrial biogenesis and causes defective axonal transport and synaptic degeneration in Huntington's disease.
Ulziibat P Shirendeb, Marcus J Calkins, Maria Manczak, Vishwanath Anekonda, Brett Dufour, Jodi L McBride, Peizhong Mao, P Hemachandra Reddy. Hum Mol Genet 2012
214
8

Huntington disease: natural history, biomarkers and prospects for therapeutics.
Christopher A Ross, Elizabeth H Aylward, Edward J Wild, Douglas R Langbehn, Jeffrey D Long, John H Warner, Rachael I Scahill, Blair R Leavitt, Julie C Stout, Jane S Paulsen,[...]. Nat Rev Neurol 2014
509
8

Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease.
Kirupa Sathasivam, Andreas Neueder, Theresa A Gipson, Christian Landles, Agnesska C Benjamin, Marie K Bondulich, Donna L Smith, Richard L M Faull, Raymund A C Roos, David Howland,[...]. Proc Natl Acad Sci U S A 2013
257
8

Pathophysiology of Huntington's disease: time-dependent alterations in synaptic and receptor function.
L A Raymond, V M André, C Cepeda, C M Gladding, A J Milnerwood, M S Levine. Neuroscience 2011
186
7

Systematic behavioral evaluation of Huntington's disease transgenic and knock-in mouse models.
Liliana Menalled, Bassem F El-Khodor, Monica Patry, Mayte Suárez-Fariñas, Samantha J Orenstein, Benjamin Zahasky, Christina Leahy, Vanessa Wheeler, X William Yang, Marcy MacDonald,[...]. Neurobiol Dis 2009
219
7

Molecular mechanisms and potential therapeutical targets in Huntington's disease.
Chiara Zuccato, Marta Valenza, Elena Cattaneo. Physiol Rev 2010
545
7

Mitochondrial defect in Huntington's disease caudate nucleus.
M Gu, M T Gash, V M Mann, F Javoy-Agid, J M Cooper, A H Schapira. Ann Neurol 1996
536
7

Evidence for more widespread cerebral pathology in early HD: an MRI-based morphometric analysis.
H D Rosas, W J Koroshetz, Y I Chen, C Skeuse, M Vangel, M E Cudkowicz, K Caplan, K Marek, L J Seidman, N Makris,[...]. Neurology 2003
365
7

Differential loss of striatal projection neurons in Huntington disease.
A Reiner, R L Albin, K D Anderson, C J D'Amato, J B Penney, A B Young. Proc Natl Acad Sci U S A 1988
721
7

Decreased expression of striatal signaling genes in a mouse model of Huntington's disease.
R Luthi-Carter, A Strand, N L Peters, S M Solano, Z R Hollingsworth, A S Menon, A S Frey, B S Spektor, E B Penney, G Schilling,[...]. Hum Mol Genet 2000
559
7

A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration.
J G Hodgson, N Agopyan, C A Gutekunst, B R Leavitt, F LePiane, R Singaraja, D J Smith, N Bissada, K McCutcheon, J Nasir,[...]. Neuron 1999
618
7

Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release.
Yeun Su Choo, Gail V W Johnson, Marcy MacDonald, Peter J Detloff, Mathieu Lesort. Hum Mol Genet 2004
340
7

Network organization of the huntingtin proteomic interactome in mammalian brain.
Dyna I Shirasaki, Erin R Greiner, Ismael Al-Ramahi, Michelle Gray, Pinmanee Boontheung, Daniel H Geschwind, Juan Botas, Giovanni Coppola, Steve Horvath, Joseph A Loo,[...]. Neuron 2012
165
7

Length-dependent gametic CAG repeat instability in the Huntington's disease knock-in mouse.
V C Wheeler, W Auerbach, J K White, J Srinidhi, A Auerbach, A Ryan, M P Duyao, V Vrbanac, M Weaver, J F Gusella,[...]. Hum Mol Genet 1999
275
7

Characterization of neurophysiological and behavioral changes, MRI brain volumetry and 1H MRS in zQ175 knock-in mouse model of Huntington's disease.
Taneli Heikkinen, Kimmo Lehtimäki, Nina Vartiainen, Jukka Puoliväli, Susan J Hendricks, Jack R Glaser, Amyaouch Bradaia, Kristian Wadel, Chrystelle Touller, Outi Kontkanen,[...]. PLoS One 2012
136
7

Huntington's disease: a clinical review.
P McColgan, S J Tabrizi. Eur J Neurol 2018
240
7

A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease.
Maria Björkqvist, Edward J Wild, Jenny Thiele, Aurelio Silvestroni, Ralph Andre, Nayana Lahiri, Elsa Raibon, Richard V Lee, Caroline L Benn, Denis Soulet,[...]. J Exp Med 2008
366
7

Role of brain-derived neurotrophic factor in Huntington's disease.
Chiara Zuccato, Elena Cattaneo. Prog Neurobiol 2007
363
6

Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin.
G Schilling, M W Becher, A H Sharp, H A Jinnah, K Duan, J A Kotzuk, H H Slunt, T Ratovitski, J K Cooper, N A Jenkins,[...]. Hum Mol Genet 1999
576
6

Proteomic and oxidative stress analysis in human brain samples of Huntington disease.
Ma Alba Sorolla, Gemma Reverter-Branchat, Jordi Tamarit, Isidre Ferrer, Joaquim Ros, Elisa Cabiscol. Free Radic Biol Med 2008
189
6


Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines.
Alexander V Panov, Claire-Anne Gutekunst, Blair R Leavitt, Michael R Hayden, James R Burke, Warren J Strittmatter, J Timothy Greenamyre. Nat Neurosci 2002
734
6

Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules.
Laurent R Gauthier, Bénédicte C Charrin, Maria Borrell-Pagès, Jim P Dompierre, Hélène Rangone, Fabrice P Cordelières, Jan De Mey, Marcy E MacDonald, Volkmar Lessmann, Sandrine Humbert,[...]. Cell 2004
775
6

Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration.
Libin Cui, Hyunkyung Jeong, Fran Borovecki, Christopher N Parkhurst, Naoko Tanese, Dimitri Krainc. Cell 2006
736
6

Huntington's disease: underlying molecular mechanisms and emerging concepts.
John Labbadia, Richard I Morimoto. Trends Biochem Sci 2013
199
6

Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death.
Montserrat Arrasate, Siddhartha Mitra, Erik S Schweitzer, Mark R Segal, Steven Finkbeiner. Nature 2004
6

Nuclear and neuropil aggregates in Huntington's disease: relationship to neuropathology.
C A Gutekunst, S H Li, H Yi, J S Mulroy, S Kuemmerle, R Jones, D Rye, R J Ferrante, S M Hersch, X J Li. J Neurosci 1999
612
6

Predictors of phenotypic progression and disease onset in premanifest and early-stage Huntington's disease in the TRACK-HD study: analysis of 36-month observational data.
Sarah J Tabrizi, Rachael I Scahill, Gail Owen, Alexandra Durr, Blair R Leavitt, Raymund A Roos, Beth Borowsky, Bernhard Landwehrmeyer, Chris Frost, Hans Johnson,[...]. Lancet Neurol 2013
474
6

Multiple sources of striatal inhibition are differentially affected in Huntington's disease mouse models.
Carlos Cepeda, Laurie Galvan, Sandra M Holley, Shilpa P Rao, Véronique M André, Elian P Botelho, Jane Y Chen, Joseph B Watson, Karl Deisseroth, Michael S Levine. J Neurosci 2013
76
7

Proteolysis of mutant huntingtin produces an exon 1 fragment that accumulates as an aggregated protein in neuronal nuclei in Huntington disease.
Christian Landles, Kirupa Sathasivam, Andreas Weiss, Ben Woodman, Hilary Moffitt, Steve Finkbeiner, Banghua Sun, Juliette Gafni, Lisa M Ellerby, Yvon Trottier,[...]. J Biol Chem 2010
209
6

Altered Balance of Activity in the Striatal Direct and Indirect Pathways in Mouse Models of Huntington's Disease.
Véronique M André, Yvette E Fisher, Michael S Levine. Front Syst Neurosci 2011
57
8

Differential electrophysiological changes in striatal output neurons in Huntington's disease.
Véronique M André, Carlos Cepeda, Yvette E Fisher, My Huynh, Nora Bardakjian, Sumedha Singh, X William Yang, Michael S Levine. J Neurosci 2011
90
5

Preferential loss of striato-external pallidal projection neurons in presymptomatic Huntington's disease.
R L Albin, A Reiner, K D Anderson, L S Dure, B Handelin, R Balfour, W O Whetsell, J B Penney, A B Young. Ann Neurol 1992
251
5


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.