C J Ferro, J C Spratt, W G Haynes, D J Webb. Circulation 1998
Times Cited: 140
Times Cited: 140
Times Cited
Times Co-cited
Similarity
Angiotensin-neprilysin inhibition versus enalapril in heart failure.
John J V McMurray, Milton Packer, Akshay S Desai, Jianjian Gong, Martin P Lefkowitz, Adel R Rizkala, Jean L Rouleau, Victor C Shi, Scott D Solomon, Karl Swedberg,[...]. N Engl J Med 2014
John J V McMurray, Milton Packer, Akshay S Desai, Jianjian Gong, Martin P Lefkowitz, Adel R Rizkala, Jean L Rouleau, Victor C Shi, Scott D Solomon, Karl Swedberg,[...]. N Engl J Med 2014
49
Pharmacokinetics and pharmacodynamics of LCZ696, a novel dual-acting angiotensin receptor-neprilysin inhibitor (ARNi).
Jessie Gu, Adele Noe, Priya Chandra, Suliman Al-Fayoumi, Monica Ligueros-Saylan, Ramesh Sarangapani, Suzanne Maahs, Gary Ksander, Dean F Rigel, Arco Y Jeng,[...]. J Clin Pharmacol 2010
Jessie Gu, Adele Noe, Priya Chandra, Suliman Al-Fayoumi, Monica Ligueros-Saylan, Ramesh Sarangapani, Suzanne Maahs, Gary Ksander, Dean F Rigel, Arco Y Jeng,[...]. J Clin Pharmacol 2010
45
Comparison of omapatrilat and enalapril in patients with chronic heart failure: the Omapatrilat Versus Enalapril Randomized Trial of Utility in Reducing Events (OVERTURE).
Milton Packer, Robert M Califf, Marvin A Konstam, Henry Krum, John J McMurray, Jean-Lucien Rouleau, Karl Swedberg. Circulation 2002
Milton Packer, Robert M Califf, Marvin A Konstam, Henry Krum, John J McMurray, Jean-Lucien Rouleau, Karl Swedberg. Circulation 2002
43
Blood-pressure reduction with LCZ696, a novel dual-acting inhibitor of the angiotensin II receptor and neprilysin: a randomised, double-blind, placebo-controlled, active comparator study.
Luis Miguel Ruilope, Andrej Dukat, Michael Böhm, Yves Lacourcière, Jianjian Gong, Martin P Lefkowitz. Lancet 2010
Luis Miguel Ruilope, Andrej Dukat, Michael Böhm, Yves Lacourcière, Jianjian Gong, Martin P Lefkowitz. Lancet 2010
43
Omapatrilat and enalapril in patients with hypertension: the Omapatrilat Cardiovascular Treatment vs. Enalapril (OCTAVE) trial.
John B Kostis, Milton Packer, Henry R Black, Roland Schmieder, David Henry, Elliott Levy. Am J Hypertens 2004
John B Kostis, Milton Packer, Henry R Black, Roland Schmieder, David Henry, Elliott Levy. Am J Hypertens 2004
41
The angiotensin receptor neprilysin inhibitor LCZ696 in heart failure with preserved ejection fraction: a phase 2 double-blind randomised controlled trial.
Scott D Solomon, Michael Zile, Burkert Pieske, Adriaan Voors, Amil Shah, Elisabeth Kraigher-Krainer, Victor Shi, Toni Bransford, Madoka Takeuchi, Jianjian Gong,[...]. Lancet 2012
Scott D Solomon, Michael Zile, Burkert Pieske, Adriaan Voors, Amil Shah, Elisabeth Kraigher-Krainer, Victor Shi, Toni Bransford, Madoka Takeuchi, Jianjian Gong,[...]. Lancet 2012
34
Comparison of candoxatril and atrial natriuretic factor in healthy men. Effects on hemodynamics, sympathetic activity, heart rate variability, and endothelin.
S Ando, M A Rahman, G C Butler, B L Senn, J S Floras. Hypertension 1995
S Ando, M A Rahman, G C Butler, B L Senn, J S Floras. Hypertension 1995
28
Comparison of vasopeptidase inhibitor, omapatrilat, and lisinopril on exercise tolerance and morbidity in patients with heart failure: IMPRESS randomised trial.
J L Rouleau, M A Pfeffer, D J Stewart, D Isaac, F Sestier, E K Kerut, C B Porter, G Proulx, C Qian, A J Block. Lancet 2000
J L Rouleau, M A Pfeffer, D J Stewart, D Isaac, F Sestier, E K Kerut, C B Porter, G Proulx, C Qian, A J Block. Lancet 2000
27
Candoxatril, a neutral endopeptidase inhibitor: efficacy and tolerability in essential hypertension.
E G Bevan, J M Connell, J Doyle, H A Carmichael, D L Davies, A R Lorimer, G T McInnes. J Hypertens 1992
E G Bevan, J M Connell, J Doyle, H A Carmichael, D L Davies, A R Lorimer, G T McInnes. J Hypertens 1992
26
Effect of nesiritide in patients with acute decompensated heart failure.
C M O'Connor, R C Starling, A F Hernandez, P W Armstrong, K Dickstein, V Hasselblad, G M Heizer, M Komajda, B M Massie, J J V McMurray,[...]. N Engl J Med 2011
C M O'Connor, R C Starling, A F Hernandez, P W Armstrong, K Dickstein, V Hasselblad, G M Heizer, M Komajda, B M Massie, J J V McMurray,[...]. N Engl J Med 2011
25
Angiotensin receptor neprilysin inhibition compared with enalapril on the risk of clinical progression in surviving patients with heart failure.
Milton Packer, John J V McMurray, Akshay S Desai, Jianjian Gong, Martin P Lefkowitz, Adel R Rizkala, Jean L Rouleau, Victor C Shi, Scott D Solomon, Karl Swedberg,[...]. Circulation 2015
Milton Packer, John J V McMurray, Akshay S Desai, Jianjian Gong, Martin P Lefkowitz, Adel R Rizkala, Jean L Rouleau, Victor C Shi, Scott D Solomon, Karl Swedberg,[...]. Circulation 2015
23
Effect of bradykinin metabolism inhibitors on evoked hypotension in rats: rank efficacy of enzymes associated with bradykinin-mediated angioedema.
R M Fryer, J Segreti, P N Banfor, D L Widomski, B J Backes, C W Lin, S J Ballaron, B F Cox, J M Trevillyan, G A Reinhart,[...]. Br J Pharmacol 2008
R M Fryer, J Segreti, P N Banfor, D L Widomski, B J Backes, C W Lin, S J Ballaron, B F Cox, J M Trevillyan, G A Reinhart,[...]. Br J Pharmacol 2008
22
Effects of UK 69 578: a novel atriopeptidase inhibitor.
D B Northridge, A G Jardine, C T Alabaster, P L Barclay, J M Connell, H J Dargie, S G Dilly, I N Findlay, A F Lever, G M Samuels. Lancet 1989
D B Northridge, A G Jardine, C T Alabaster, P L Barclay, J M Connell, H J Dargie, S G Dilly, I N Findlay, A F Lever, G M Samuels. Lancet 1989
21
Efficacy and safety of LCZ696, a first-in-class angiotensin receptor neprilysin inhibitor, in Asian patients with hypertension: a randomized, double-blind, placebo-controlled study.
Kazuomi Kario, Ningling Sun, Fu-Tien Chiang, Ouppatham Supasyndh, Sang Hong Baek, Akiko Inubushi-Molessa, Ying Zhang, Hiromi Gotou, Martin Lefkowitz, Jack Zhang. Hypertension 2014
Kazuomi Kario, Ningling Sun, Fu-Tien Chiang, Ouppatham Supasyndh, Sang Hong Baek, Akiko Inubushi-Molessa, Ying Zhang, Hiromi Gotou, Martin Lefkowitz, Jack Zhang. Hypertension 2014
21
Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure.
Salim Yusuf, Bertram Pitt, Clarence E Davis, William B Hood, Jay N Cohn. N Engl J Med 1991
Salim Yusuf, Bertram Pitt, Clarence E Davis, William B Hood, Jay N Cohn. N Engl J Med 1991
19
Dual angiotensin receptor and neprilysin inhibition as an alternative to angiotensin-converting enzyme inhibition in patients with chronic systolic heart failure: rationale for and design of the Prospective comparison of ARNI with ACEI to Determine Impact on Global Mortality and morbidity in Heart Failure trial (PARADIGM-HF).
John J V McMurray, Milton Packer, Akshay S Desai, Jim Gong, Martin P Lefkowitz, Adel R Rizkala, Jean Rouleau, Victor C Shi, Scott D Solomon, Karl Swedberg,[...]. Eur J Heart Fail 2013
John J V McMurray, Milton Packer, Akshay S Desai, Jim Gong, Martin P Lefkowitz, Adel R Rizkala, Jean Rouleau, Victor C Shi, Scott D Solomon, Karl Swedberg,[...]. Eur J Heart Fail 2013
18
Neutral endopeptidase inhibition and the natriuretic peptide system: an evolving strategy in cardiovascular therapeutics.
Sarah Mangiafico, Lisa C Costello-Boerrigter, Ingrid A Andersen, Alessandro Cataliotti, John C Burnett. Eur Heart J 2013
Sarah Mangiafico, Lisa C Costello-Boerrigter, Ingrid A Andersen, Alessandro Cataliotti, John C Burnett. Eur Heart J 2013
18
The effect of the neutral endopeptidase inhibitor drug, candoxatril, on circulating levels of two of the most potent vasoactive peptides.
G McDowell, W Coutie, C Shaw, K D Buchanan, A D Struthers, D P Nicholls. Br J Clin Pharmacol 1997
G McDowell, W Coutie, C Shaw, K D Buchanan, A D Struthers, D P Nicholls. Br J Clin Pharmacol 1997
22
A randomized trial of the angiotensin-receptor blocker valsartan in chronic heart failure.
J N Cohn, G Tognoni. N Engl J Med 2001
J N Cohn, G Tognoni. N Engl J Med 2001
17
Effects of enalapril on mortality in severe congestive heart failure. Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS).
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16
16
16
Lack of efficacy of neutral endopeptidase inhibitor ecadotril in heart failure. The International Ecadotril Multi-centre Dose-ranging Study Investigators.
J G Cleland, K Swedberg. Lancet 1998
J G Cleland, K Swedberg. Lancet 1998
17
Intravenous nesiritide vs nitroglycerin for treatment of decompensated congestive heart failure: a randomized controlled trial.
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15
Hydrolysis of human and pig brain natriuretic peptides, urodilatin, C-type natriuretic peptide and some C-receptor ligands by endopeptidase-24.11.
A J Kenny, A Bourne, J Ingram. Biochem J 1993
A J Kenny, A Bourne, J Ingram. Biochem J 1993
14
Neutral endopeptidase 24.11 (enkephalinase) and related regulators of peptide hormones.
E G Erdös, R A Skidgel. FASEB J 1989
E G Erdös, R A Skidgel. FASEB J 1989
14
Chronic inhibition of endopeptidase 24.11 in essential hypertension: evidence for enhanced atrial natriuretic peptide and angiotensin II.
A M Richards, G A Wittert, I G Crozier, E A Espiner, T G Yandle, H Ikram, C Frampton. J Hypertens 1993
A M Richards, G A Wittert, I G Crozier, E A Espiner, T G Yandle, H Ikram, C Frampton. J Hypertens 1993
13
A rapid and potent natriuretic response to intravenous injection of atrial myocardial extract in rats.
A J de Bold, H B Borenstein, A T Veress, H Sonnenberg. Life Sci 1981
A J de Bold, H B Borenstein, A T Veress, H Sonnenberg. Life Sci 1981
13
Metabolism of neuropeptides. Hydrolysis of the angiotensins, bradykinin, substance P and oxytocin by pig kidney microvillar membranes.
S L Stephenson, A J Kenny. Biochem J 1987
S L Stephenson, A J Kenny. Biochem J 1987
13
Concomitant angiotensin AT1 receptor antagonism and neprilysin inhibition produces omapatrilat-like antihypertensive effects without promoting tracheal plasma extravasation in the rat.
Laxminarayan G Hegde, Cecile Yu, Travis Renner, Harold Thibodeaux, Scott R Armstrong, Timothy Park, Madhavi Cheruvu, Rachael Olsufka, Erik R Sandvik, Cassie E Lane,[...]. J Cardiovasc Pharmacol 2011
Laxminarayan G Hegde, Cecile Yu, Travis Renner, Harold Thibodeaux, Scott R Armstrong, Timothy Park, Madhavi Cheruvu, Rachael Olsufka, Erik R Sandvik, Cassie E Lane,[...]. J Cardiovasc Pharmacol 2011
25
Angiotensin receptor neprilysin inhibitor LCZ696 attenuates cardiac remodeling and dysfunction after myocardial infarction by reducing cardiac fibrosis and hypertrophy.
Thomas G von Lueder, Bing H Wang, Andrew R Kompa, Li Huang, Randy Webb, Pierre Jordaan, Dan Atar, Henry Krum. Circ Heart Fail 2015
Thomas G von Lueder, Bing H Wang, Andrew R Kompa, Li Huang, Randy Webb, Pierre Jordaan, Dan Atar, Henry Krum. Circ Heart Fail 2015
12
Effect of the angiotensin-receptor-neprilysin inhibitor LCZ696 compared with enalapril on mode of death in heart failure patients.
Akshay S Desai, John J V McMurray, Milton Packer, Karl Swedberg, Jean L Rouleau, Fabian Chen, Jianjian Gong, Adel R Rizkala, Abdel Brahimi, Brian Claggett,[...]. Eur Heart J 2015
Akshay S Desai, John J V McMurray, Milton Packer, Karl Swedberg, Jean L Rouleau, Fabian Chen, Jianjian Gong, Adel R Rizkala, Abdel Brahimi, Brian Claggett,[...]. Eur Heart J 2015
12
Protection of atrial natriuretic factor against degradation: diuretic and natriuretic responses after in vivo inhibition of enkephalinase (EC 3.4.24.11) by acetorphan.
C Gros, A Souque, J C Schwartz, J Duchier, A Cournot, P Baumer, J M Lecomte. Proc Natl Acad Sci U S A 1989
C Gros, A Souque, J C Schwartz, J Duchier, A Cournot, P Baumer, J M Lecomte. Proc Natl Acad Sci U S A 1989
11
Effect of inhibition of endopeptidase 24.11 on responses to angiotensin II in human volunteers.
A M Richards, G A Wittert, E A Espiner, T G Yandle, H Ikram, C Frampton. Circ Res 1992
A M Richards, G A Wittert, E A Espiner, T G Yandle, H Ikram, C Frampton. Circ Res 1992
14
2013 ACCF/AHA guideline for the management of heart failure: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines.
Clyde W Yancy, Mariell Jessup, Biykem Bozkurt, Javed Butler, Donald E Casey, Mark H Drazner, Gregg C Fonarow, Stephen A Geraci, Tamara Horwich, James L Januzzi,[...]. J Am Coll Cardiol 2013
Clyde W Yancy, Mariell Jessup, Biykem Bozkurt, Javed Butler, Donald E Casey, Mark H Drazner, Gregg C Fonarow, Stephen A Geraci, Tamara Horwich, James L Januzzi,[...]. J Am Coll Cardiol 2013
11
Short-term risk of death after treatment with nesiritide for decompensated heart failure: a pooled analysis of randomized controlled trials.
Jonathan D Sackner-Bernstein, Marcin Kowalski, Marshal Fox, Keith Aaronson. JAMA 2005
Jonathan D Sackner-Bernstein, Marcin Kowalski, Marshal Fox, Keith Aaronson. JAMA 2005
10
The purification and specificity of a neutral endopeptidase from rabbit kidney brush border.
M A Kerr, A J Kenny. Biochem J 1974
M A Kerr, A J Kenny. Biochem J 1974
10
Natriuretic peptides, their receptors, and cyclic guanosine monophosphate-dependent signaling functions.
Lincoln R Potter, Sarah Abbey-Hosch, Deborah M Dickey. Endocr Rev 2006
Lincoln R Potter, Sarah Abbey-Hosch, Deborah M Dickey. Endocr Rev 2006
10
The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators.
B Pitt, F Zannad, W J Remme, R Cody, A Castaigne, A Perez, J Palensky, J Wittes. N Engl J Med 1999
B Pitt, F Zannad, W J Remme, R Cody, A Castaigne, A Perez, J Palensky, J Wittes. N Engl J Med 1999
10
Dicarboxylic acid dipeptide neutral endopeptidase inhibitors.
G M Ksander, R D Ghai, R deJesus, C G Diefenbacher, A Yuan, C Berry, Y Sakane, A Trapani. J Med Chem 1995
G M Ksander, R D Ghai, R deJesus, C G Diefenbacher, A Yuan, C Berry, Y Sakane, A Trapani. J Med Chem 1995
22
Independence of the blood pressure lowering effect and efficacy of the angiotensin receptor neprilysin inhibitor, LCZ696, in patients with heart failure with preserved ejection fraction: an analysis of the PARAMOUNT trial.
Pardeep S Jhund, Brian Claggett, Milton Packer, Michael R Zile, Adriaan A Voors, Burkert Pieske, Martin Lefkowitz, Victor Shi, Toni Bransford, John J V McMurray,[...]. Eur J Heart Fail 2014
Pardeep S Jhund, Brian Claggett, Milton Packer, Michael R Zile, Adriaan A Voors, Burkert Pieske, Martin Lefkowitz, Victor Shi, Toni Bransford, John J V McMurray,[...]. Eur J Heart Fail 2014
15
Comparison of the short-term effects of candoxatril, an orally active neutral endopeptidase inhibitor, and frusemide in the treatment of patients with chronic heart failure.
D B Northridge, D E Newby, E Rooney, J Norrie, H J Dargie. Am Heart J 1999
D B Northridge, D E Newby, E Rooney, J Norrie, H J Dargie. Am Heart J 1999
25
Efficacy and safety of LCZ696 (sacubitril-valsartan) according to age: insights from PARADIGM-HF.
Pardeep S Jhund, Michael Fu, Edmundo Bayram, Chen-Huan Chen, Marta Negrusz-Kawecka, Arvo Rosenthal, Akshay S Desai, Martin P Lefkowitz, Adel R Rizkala, Jean L Rouleau,[...]. Eur Heart J 2015
Pardeep S Jhund, Michael Fu, Edmundo Bayram, Chen-Huan Chen, Marta Negrusz-Kawecka, Arvo Rosenthal, Akshay S Desai, Martin P Lefkowitz, Adel R Rizkala, Jean L Rouleau,[...]. Eur Heart J 2015
10
Omapatrilat reduces pulse pressure and proximal aortic stiffness in patients with systolic hypertension: results of the conduit hemodynamics of omapatrilat international research study.
Gary F Mitchell, Joseph L Izzo, Yves Lacourcière, Jean-Pascal Ouellet, Joel Neutel, Chunlin Qian, Linda J Kerwin, Alan J Block, Marc A Pfeffer. Circulation 2002
Gary F Mitchell, Joseph L Izzo, Yves Lacourcière, Jean-Pascal Ouellet, Joel Neutel, Chunlin Qian, Linda J Kerwin, Alan J Block, Marc A Pfeffer. Circulation 2002
9
Dual metalloprotease inhibitors: mercaptoacetyl-based fused heterocyclic dipeptide mimetics as inhibitors of angiotensin-converting enzyme and neutral endopeptidase.
J A Robl, C Q Sun, J Stevenson, D E Ryono, L M Simpkins, M P Cimarusti, T Dejneka, W A Slusarchyk, S Chao, L Stratton,[...]. J Med Chem 1997
J A Robl, C Q Sun, J Stevenson, D E Ryono, L M Simpkins, M P Cimarusti, T Dejneka, W A Slusarchyk, S Chao, L Stratton,[...]. J Med Chem 1997
9
Intravenous nesiritide, a natriuretic peptide, in the treatment of decompensated congestive heart failure. Nesiritide Study Group.
W S Colucci, U Elkayam, D P Horton, W T Abraham, R C Bourge, A D Johnson, L E Wagoner, M M Givertz, C S Liang, M Neibaur,[...]. N Engl J Med 2000
W S Colucci, U Elkayam, D P Horton, W T Abraham, R C Bourge, A D Johnson, L E Wagoner, M M Givertz, C S Liang, M Neibaur,[...]. N Engl J Med 2000
9
Candoxatril, an orally active neutral endopeptidase inhibitor, raises plasma atrial natriuretic factor and is natriuretic in essential hypertension.
J E O'Connell, A G Jardine, G Davidson, J M Connell. J Hypertens 1992
J E O'Connell, A G Jardine, G Davidson, J M Connell. J Hypertens 1992
16
Eplerenone in patients with systolic heart failure and mild symptoms.
Faiez Zannad, John J V McMurray, Henry Krum, Dirk J van Veldhuisen, Karl Swedberg, Harry Shi, John Vincent, Stuart J Pocock, Bertram Pitt. N Engl J Med 2011
Faiez Zannad, John J V McMurray, Henry Krum, Dirk J van Veldhuisen, Karl Swedberg, Harry Shi, John Vincent, Stuart J Pocock, Bertram Pitt. N Engl J Med 2011
9
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.