T Sato, M Oyake, K Nakamura, K Nakao, Y Fukusima, O Onodera, S Igarashi, H Takano, K Kikugawa, Y Ishida, T Shimohata, R Koide, T Ikeuchi, H Tanaka, N Futamura, R Matsumura, T Takayanagi, F Tanaka, G Sobue, O Komure, M Takahashi, A Sano, Y Ichikawa, J Goto, I Kanazawa. Hum Mol Genet 1999
Times Cited: 86
Times Cited: 86
Times Cited
Times Co-cited
Similarity
Instability of highly expanded CAG repeats in mice transgenic for the Huntington's disease mutation.
L Mangiarini, K Sathasivam, A Mahal, R Mott, M Seller, G P Bates. Nat Genet 1997
L Mangiarini, K Sathasivam, A Mahal, R Mott, M Seller, G P Bates. Nat Genet 1997
38
Length-dependent gametic CAG repeat instability in the Huntington's disease knock-in mouse.
V C Wheeler, W Auerbach, J K White, J Srinidhi, A Auerbach, A Ryan, M P Duyao, V Vrbanac, M Weaver, J F Gusella,[...]. Hum Mol Genet 1999
V C Wheeler, W Auerbach, J K White, J Srinidhi, A Auerbach, A Ryan, M P Duyao, V Vrbanac, M Weaver, J F Gusella,[...]. Hum Mol Genet 1999
32
Msh2 deficiency prevents in vivo somatic instability of the CAG repeat in Huntington disease transgenic mice.
K Manley, T L Shirley, L Flaherty, A Messer. Nat Genet 1999
K Manley, T L Shirley, L Flaherty, A Messer. Nat Genet 1999
32
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice.
L Mangiarini, K Sathasivam, M Seller, B Cozens, A Harper, C Hetherington, M Lawton, Y Trottier, H Lehrach, S W Davies,[...]. Cell 1996
L Mangiarini, K Sathasivam, M Seller, B Cozens, A Harper, C Hetherington, M Lawton, Y Trottier, H Lehrach, S W Davies,[...]. Cell 1996
30
Increased trinucleotide repeat instability with advanced maternal age.
M D Kaytor, E N Burright, L A Duvick, H Y Zoghbi, H T Orr. Hum Mol Genet 1997
M D Kaytor, E N Burright, L A Duvick, H Y Zoghbi, H T Orr. Hum Mol Genet 1997
34
Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation.
S W Davies, M Turmaine, B A Cozens, M DiFiglia, A H Sharp, C A Ross, E Scherzinger, E E Wanker, L Mangiarini, G P Bates. Cell 1997
S W Davies, M Turmaine, B A Cozens, M DiFiglia, A H Sharp, C A Ross, E Scherzinger, E E Wanker, L Mangiarini, G P Bates. Cell 1997
26
Hypermutable myotonic dystrophy CTG repeats in transgenic mice.
D G Monckton, M I Coolbaugh, K T Ashizawa, M J Siciliano, C T Caskey. Nat Genet 1997
D G Monckton, M I Coolbaugh, K T Ashizawa, M J Siciliano, C T Caskey. Nat Genet 1997
26
Expanded polyglutamine in the Machado-Joseph disease protein induces cell death in vitro and in vivo.
H Ikeda, M Yamaguchi, S Sugai, Y Aze, S Narumiya, A Kakizuka. Nat Genet 1996
H Ikeda, M Yamaguchi, S Sugai, Y Aze, S Narumiya, A Kakizuka. Nat Genet 1996
26
Dramatic, expansion-biased, age-dependent, tissue-specific somatic mosaicism in a transgenic mouse model of triplet repeat instability.
M T Fortune, C Vassilopoulos, M I Coolbaugh, M J Siciliano, D G Monckton. Hum Mol Genet 2000
M T Fortune, C Vassilopoulos, M I Coolbaugh, M J Siciliano, D G Monckton. Hum Mol Genet 2000
26
Unstable expansion of CAG repeat in hereditary dentatorubral-pallidoluysian atrophy (DRPLA).
R Koide, T Ikeuchi, O Onodera, H Tanaka, S Igarashi, K Endo, H Takahashi, R Kondo, A Ishikawa, T Hayashi. Nat Genet 1994
R Koide, T Ikeuchi, O Onodera, H Tanaka, S Igarashi, K Endo, H Takahashi, R Kondo, A Ishikawa, T Hayashi. Nat Genet 1994
25
Androgen receptor YAC transgenic mice carrying CAG 45 alleles show trinucleotide repeat instability.
A R La Spada, K R Peterson, S A Meadows, M E McClain, G Jeng, R S Chmelar, H A Haugen, K Chen, M J Singer, D Moore,[...]. Hum Mol Genet 1998
A R La Spada, K R Peterson, S A Meadows, M E McClain, G Jeng, R S Chmelar, H A Haugen, K Chen, M J Singer, D Moore,[...]. Hum Mol Genet 1998
32
SCA1 transgenic mice: a model for neurodegeneration caused by an expanded CAG trinucleotide repeat.
E N Burright, H B Clark, A Servadio, T Matilla, R M Feddersen, W S Yunis, L A Duvick, H Y Zoghbi, H T Orr. Cell 1995
E N Burright, H B Clark, A Servadio, T Matilla, R M Feddersen, W S Yunis, L A Duvick, H Y Zoghbi, H T Orr. Cell 1995
24
Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain.
M DiFiglia, E Sapp, K O Chase, S W Davies, G P Bates, J P Vonsattel, N Aronin. Science 1997
M DiFiglia, E Sapp, K O Chase, S W Davies, G P Bates, J P Vonsattel, N Aronin. Science 1997
23
Somatic instability of the CTG repeat in mice transgenic for the myotonic dystrophy region is age dependent but not correlated to the relative intertissue transcription levels and proliferative capacities.
A S Lia, H Seznec, H Hofmann-Radvanyi, F Radvanyi, C Duros, C Saquet, M Blanche, C Junien, G Gourdon. Hum Mol Genet 1998
A S Lia, H Seznec, H Hofmann-Radvanyi, F Radvanyi, C Duros, C Saquet, M Blanche, C Junien, G Gourdon. Hum Mol Genet 1998
29
A Huntington's disease CAG expansion at the murine Hdh locus is unstable and associated with behavioural abnormalities in mice.
P F Shelbourne, N Killeen, R F Hevner, H M Johnston, L Tecott, M Lewandoski, M Ennis, L Ramirez, Z Li, C Iannicola,[...]. Hum Mol Genet 1999
P F Shelbourne, N Killeen, R F Hevner, H M Johnston, L Tecott, M Lewandoski, M Ennis, L Ramirez, Z Li, C Iannicola,[...]. Hum Mol Genet 1999
23
Somatic mosaicism, germline expansions, germline reversions and intergenerational reductions in myotonic dystrophy males: small pool PCR analyses.
D G Monckton, L J Wong, T Ashizawa, C T Caskey. Hum Mol Genet 1995
D G Monckton, L J Wong, T Ashizawa, C T Caskey. Hum Mol Genet 1995
23
Ataxin-1 with an expanded glutamine tract alters nuclear matrix-associated structures.
P J Skinner, B T Koshy, C J Cummings, I A Klement, K Helin, A Servadio, H Y Zoghbi, H T Orr. Nature 1997
P J Skinner, B T Koshy, C J Cummings, I A Klement, K Helin, A Servadio, H Y Zoghbi, H T Orr. Nature 1997
22
Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.
F Saudou, S Finkbeiner, D Devys, M E Greenberg. Cell 1998
F Saudou, S Finkbeiner, D Devys, M E Greenberg. Cell 1998
22
Ataxin-1 nuclear localization and aggregation: role in polyglutamine-induced disease in SCA1 transgenic mice.
I A Klement, P J Skinner, M D Kaytor, H Yi, S M Hersch, H B Clark, H Y Zoghbi, H T Orr. Cell 1998
I A Klement, P J Skinner, M D Kaytor, H Yi, S M Hersch, H B Clark, H Y Zoghbi, H T Orr. Cell 1998
22
Somatic and gonadal mosaicism of the Huntington disease gene CAG repeat in brain and sperm.
H Telenius, B Kremer, Y P Goldberg, J Theilmann, S E Andrew, J Zeisler, S Adam, C Greenberg, E J Ives, L A Clarke. Nat Genet 1994
H Telenius, B Kremer, Y P Goldberg, J Theilmann, S E Andrew, J Zeisler, S Adam, C Greenberg, E J Ives, L A Clarke. Nat Genet 1994
22
Transgenic mice carrying large human genomic sequences with expanded CTG repeat mimic closely the DM CTG repeat intergenerational and somatic instability.
H Seznec, A S Lia-Baldini, C Duros, C Fouquet, C Lacroix, H Hofmann-Radvanyi, C Junien, G Gourdon. Hum Mol Genet 2000
H Seznec, A S Lia-Baldini, C Duros, C Fouquet, C Lacroix, H Hofmann-Radvanyi, C Junien, G Gourdon. Hum Mol Genet 2000
22
Somatic expansion behaviour of the (CTG)n repeat in myotonic dystrophy knock-in mice is differentially affected by Msh3 and Msh6 mismatch-repair proteins.
Walther J A A van den Broek, Marcel R Nelen, Derick G Wansink, Marga M Coerwinkel, Hein te Riele, Patricia J T A Groenen, Bé Wieringa. Hum Mol Genet 2002
Walther J A A van den Broek, Marcel R Nelen, Derick G Wansink, Marga M Coerwinkel, Hein te Riele, Patricia J T A Groenen, Bé Wieringa. Hum Mol Genet 2002
22
Intranuclear inclusions of expanded polyglutamine protein in spinocerebellar ataxia type 3.
H L Paulson, M K Perez, Y Trottier, J Q Trojanowski, S H Subramony, S S Das, P Vig, J L Mandel, K H Fischbeck, R N Pittman. Neuron 1997
H L Paulson, M K Perez, Y Trottier, J Q Trojanowski, S H Subramony, S S Das, P Vig, J L Mandel, K H Fischbeck, R N Pittman. Neuron 1997
20
Dentatorubral and pallidoluysian atrophy expansion of an unstable CAG trinucleotide on chromosome 12p.
S Nagafuchi, H Yanagisawa, K Sato, T Shirayama, E Ohsaki, M Bundo, T Takeda, K Tadokoro, I Kondo, N Murayama. Nat Genet 1994
S Nagafuchi, H Yanagisawa, K Sato, T Shirayama, E Ohsaki, M Bundo, T Takeda, K Tadokoro, I Kondo, N Murayama. Nat Genet 1994
20
Expanded polyglutamine stretches interact with TAFII130, interfering with CREB-dependent transcription.
T Shimohata, T Nakajima, M Yamada, C Uchida, O Onodera, S Naruse, T Kimura, R Koide, K Nozaki, Y Sano,[...]. Nat Genet 2000
T Shimohata, T Nakajima, M Yamada, C Uchida, O Onodera, S Naruse, T Kimura, R Koide, K Nozaki, Y Sano,[...]. Nat Genet 2000
20
Nuclear accumulation of truncated atrophin-1 fragments in a transgenic mouse model of DRPLA.
G Schilling, J D Wood, K Duan, H H Slunt, V Gonzales, M Yamada, J K Cooper, R L Margolis, N A Jenkins, N G Copeland,[...]. Neuron 1999
G Schilling, J D Wood, K Duan, H H Slunt, V Gonzales, M Yamada, J K Cooper, R L Margolis, N A Jenkins, N G Copeland,[...]. Neuron 1999
20
Trinucleotide expansion in haploid germ cells by gap repair.
I V Kovtun, C T McMurray. Nat Genet 2001
I V Kovtun, C T McMurray. Nat Genet 2001
20
Spinocerebellar ataxia type 7 (SCA7): a neurodegenerative disorder with neuronal intranuclear inclusions.
M Holmberg, C Duyckaerts, A Dürr, G Cancel, I Gourfinkel-An, P Damier, B Faucheux, Y Trottier, E C Hirsch, Y Agid,[...]. Hum Mol Genet 1998
M Holmberg, C Duyckaerts, A Dürr, G Cancel, I Gourfinkel-An, P Damier, B Faucheux, Y Trottier, E C Hirsch, Y Agid,[...]. Hum Mol Genet 1998
19
Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy.
A R La Spada, E M Wilson, D B Lubahn, A E Harding, K H Fischbeck. Nature 1991
A R La Spada, E M Wilson, D B Lubahn, A E Harding, K H Fischbeck. Nature 1991
19
Suppression of aggregate formation and apoptosis by transglutaminase inhibitors in cells expressing truncated DRPLA protein with an expanded polyglutamine stretch.
S Igarashi, R Koide, T Shimohata, M Yamada, Y Hayashi, H Takano, H Date, M Oyake, T Sato, A Sato,[...]. Nat Genet 1998
S Igarashi, R Koide, T Shimohata, M Yamada, Y Hayashi, H Takano, H Date, M Oyake, T Sato, A Sato,[...]. Nat Genet 1998
18
Moderate intergenerational and somatic instability of a 55-CTG repeat in transgenic mice.
G Gourdon, F Radvanyi, A S Lia, C Duros, M Blanche, M Abitbol, C Junien, H Hofmann-Radvanyi. Nat Genet 1997
G Gourdon, F Radvanyi, A S Lia, C Duros, M Blanche, M Abitbol, C Junien, H Hofmann-Radvanyi. Nat Genet 1997
18
Familial myoclonus epilepsy and choreoathetosis: hereditary dentatorubral-pallidoluysian atrophy.
H Naito, S Oyanagi. Neurology 1982
H Naito, S Oyanagi. Neurology 1982
18
Dramatic mutation instability in HD mouse striatum: does polyglutamine load contribute to cell-specific vulnerability in Huntington's disease?
L Kennedy, P F Shelbourne. Hum Mol Genet 2000
L Kennedy, P F Shelbourne. Hum Mol Genet 2000
18
Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity.
F C Nucifora , M Sasaki, M F Peters, H Huang, J K Cooper, M Yamada, H Takahashi, S Tsuji, J Troncoso, V L Dawson,[...]. Science 2001
F C Nucifora , M Sasaki, M F Peters, H Huang, J K Cooper, M Yamada, H Takahashi, S Tsuji, J Troncoso, V L Dawson,[...]. Science 2001
18
CTG repeat instability and size variation timing in DNA repair-deficient mice.
Cédric Savouret, Edith Brisson, Jeroen Essers, Roland Kanaar, Albert Pastink, Hein te Riele, Claudine Junien, Geneviève Gourdon. EMBO J 2003
Cédric Savouret, Edith Brisson, Jeroen Essers, Roland Kanaar, Albert Pastink, Hein te Riele, Claudine Junien, Geneviève Gourdon. EMBO J 2003
18
CAG expansions in a novel gene for Machado-Joseph disease at chromosome 14q32.1.
Y Kawaguchi, T Okamoto, M Taniwaki, M Aizawa, M Inoue, S Katayama, H Kawakami, S Nakamura, M Nishimura, I Akiguchi. Nat Genet 1994
Y Kawaguchi, T Okamoto, M Taniwaki, M Aizawa, M Inoue, S Katayama, H Kawakami, S Nakamura, M Nishimura, I Akiguchi. Nat Genet 1994
17
Analysis of germline mutation spectra at the Huntington's disease locus supports a mitotic mutation mechanism.
E P Leeflang, S Tavaré, P Marjoram, C O Neal, J Srinidhi, H MacFarlane, M E MacDonald, J F Gusella, M de Young, N S Wexler,[...]. Hum Mol Genet 1999
E P Leeflang, S Tavaré, P Marjoram, C O Neal, J Srinidhi, H MacFarlane, M E MacDonald, J F Gusella, M de Young, N S Wexler,[...]. Hum Mol Genet 1999
17
Evidence of cis-acting factors in replication-mediated trinucleotide repeat instability in primate cells.
John D Cleary, Kerrie Nichol, Yuh-Hwa Wang, Christopher E Pearson. Nat Genet 2002
John D Cleary, Kerrie Nichol, Yuh-Hwa Wang, Christopher E Pearson. Nat Genet 2002
17
16
Moderate expansion of a normally biallelic trinucleotide repeat in spinocerebellar ataxia type 2.
S M Pulst, A Nechiporuk, T Nechiporuk, S Gispert, X N Chen, I Lopes-Cendes, S Pearlman, S Starkman, G Orozco-Diaz, A Lunkes,[...]. Nat Genet 1996
S M Pulst, A Nechiporuk, T Nechiporuk, S Gispert, X N Chen, I Lopes-Cendes, S Pearlman, S Starkman, G Orozco-Diaz, A Lunkes,[...]. Nat Genet 1996
16
Somatic mosaicism of expanded CAG repeats in brains of patients with dentatorubral-pallidoluysian atrophy: cellular population-dependent dynamics of mitotic instability.
H Takano, O Onodera, H Takahashi, S Igarashi, M Yamada, M Oyake, T Ikeuchi, R Koide, H Tanaka, K Iwabuchi,[...]. Am J Hum Genet 1996
H Takano, O Onodera, H Takahashi, S Igarashi, M Yamada, M Oyake, T Ikeuchi, R Koide, H Tanaka, K Iwabuchi,[...]. Am J Hum Genet 1996
21
Stability of a CTG/CAG trinucleotide repeat in yeast is dependent on its orientation in the genome.
C H Freudenreich, J B Stavenhagen, V A Zakian. Mol Cell Biol 1997
C H Freudenreich, J B Stavenhagen, V A Zakian. Mol Cell Biol 1997
16
Expansion and deletion of CTG repeats from human disease genes are determined by the direction of replication in E. coli.
S Kang, A Jaworski, K Ohshima, R D Wells. Nat Genet 1995
S Kang, A Jaworski, K Ohshima, R D Wells. Nat Genet 1995
16
Progression of somatic CTG repeat length heterogeneity in the blood cells of myotonic dystrophy patients.
L Martorell, D G Monckton, J Gamez, K J Johnson, I Gich, A Lopez de Munain, M Baiget. Hum Mol Genet 1998
L Martorell, D G Monckton, J Gamez, K J Johnson, I Gich, A Lopez de Munain, M Baiget. Hum Mol Genet 1998
16
Molecular basis of myotonic dystrophy: expansion of a trinucleotide (CTG) repeat at the 3' end of a transcript encoding a protein kinase family member.
J D Brook, M E McCurrach, H G Harley, A J Buckler, D Church, H Aburatani, K Hunter, V P Stanton, J P Thirion, T Hudson. Cell 1992
J D Brook, M E McCurrach, H G Harley, A J Buckler, D Church, H Aburatani, K Hunter, V P Stanton, J P Thirion, T Hudson. Cell 1992
16
Cis-acting modifiers of expanded CAG/CTG triplet repeat expandability: associations with flanking GC content and proximity to CpG islands.
G J Brock, N H Anderson, D G Monckton. Hum Mol Genet 1999
G J Brock, N H Anderson, D G Monckton. Hum Mol Genet 1999
16
A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration.
J G Hodgson, N Agopyan, C A Gutekunst, B R Leavitt, F LePiane, R Singaraja, D J Smith, N Bissada, K McCutcheon, J Nasir,[...]. Neuron 1999
J G Hodgson, N Agopyan, C A Gutekunst, B R Leavitt, F LePiane, R Singaraja, D J Smith, N Bissada, K McCutcheon, J Nasir,[...]. Neuron 1999
16
Myotonic dystrophy patients have larger CTG expansions in skeletal muscle than in leukocytes.
C A Thornton, K Johnson, R T Moxley. Ann Neurol 1994
C A Thornton, K Johnson, R T Moxley. Ann Neurol 1994
16
Autosomal dominant cerebellar ataxia (SCA6) associated with small polyglutamine expansions in the alpha 1A-voltage-dependent calcium channel.
O Zhuchenko, J Bailey, P Bonnen, T Ashizawa, D W Stockton, C Amos, W B Dobyns, S H Subramony, H Y Zoghbi, C C Lee. Nat Genet 1997
O Zhuchenko, J Bailey, P Bonnen, T Ashizawa, D W Stockton, C Amos, W B Dobyns, S H Subramony, H Y Zoghbi, C C Lee. Nat Genet 1997
16
SCA17, a novel autosomal dominant cerebellar ataxia caused by an expanded polyglutamine in TATA-binding protein.
K Nakamura, S Y Jeong, T Uchihara, M Anno, K Nagashima, T Nagashima, S Ikeda, S Tsuji, I Kanazawa. Hum Mol Genet 2001
K Nakamura, S Y Jeong, T Uchihara, M Anno, K Nagashima, T Nagashima, S Ikeda, S Tsuji, I Kanazawa. Hum Mol Genet 2001
16
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.