A citation-based method for searching scientific literature

V C Wheeler, W Auerbach, J K White, J Srinidhi, A Auerbach, A Ryan, M P Duyao, V Vrbanac, M Weaver, J F Gusella, A L Joyner, M E MacDonald. Hum Mol Genet 1999
Times Cited: 276







List of co-cited articles
1201 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity



Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice.
L Mangiarini, K Sathasivam, M Seller, B Cozens, A Harper, C Hetherington, M Lawton, Y Trottier, H Lehrach, S W Davies,[...]. Cell 1996
51

Neuropathological classification of Huntington's disease.
J P Vonsattel, R H Myers, T J Stevens, R J Ferrante, E D Bird, E P Richardson. J Neuropathol Exp Neurol 1985
33

Neurological abnormalities in a knock-in mouse model of Huntington's disease.
C H Lin, S Tallaksen-Greene, W M Chien, J A Cearley, W S Jackson, A B Crouse, S Ren, X J Li, R L Albin, P J Detloff. Hum Mol Genet 2001
435
25

Dramatic tissue-specific mutation length increases are an early molecular event in Huntington disease pathogenesis.
Laura Kennedy, Elizabeth Evans, Chiung-Mei Chen, Lyndsey Craven, Peter J Detloff, Margaret Ennis, Peggy F Shelbourne. Hum Mol Genet 2003
207
25

Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin.
G Schilling, M W Becher, A H Sharp, H A Jinnah, K Duan, J A Kotzuk, H H Slunt, T Ratovitski, J K Cooper, N A Jenkins,[...]. Hum Mol Genet 1999
578
24

Full-length human mutant huntingtin with a stable polyglutamine repeat can elicit progressive and selective neuropathogenesis in BACHD mice.
Michelle Gray, Dyna I Shirasaki, Carlos Cepeda, Véronique M André, Brian Wilburn, Xiao-Hong Lu, Jifang Tao, Irene Yamazaki, Shi-Hua Li, Yi E Sun,[...]. J Neurosci 2008
423
23

Intergenerational and striatal CAG repeat instability in Huntington's disease knock-in mice involve different DNA repair genes.
Ella Dragileva, Audrey Hendricks, Allison Teed, Tammy Gillis, Edith T Lopez, Errol C Friedberg, Raju Kucherlapati, Winfried Edelmann, Kathryn L Lunetta, Marcy E MacDonald,[...]. Neurobiol Dis 2009
135
22

Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease.
Elizabeth J Slow, Jeremy van Raamsdonk, Daniel Rogers, Sarah H Coleman, Rona K Graham, Yu Deng, Rosemary Oh, Nagat Bissada, Sazzad M Hossain, Yu-Zhou Yang,[...]. Hum Mol Genet 2003
569
22

Huntingtin is required for neurogenesis and is not impaired by the Huntington's disease CAG expansion.
J K White, W Auerbach, M P Duyao, J P Vonsattel, J F Gusella, A L Joyner, M E MacDonald. Nat Genet 1997
365
22

The relationship between trinucleotide (CAG) repeat length and clinical features of Huntington's disease.
S E Andrew, Y P Goldberg, B Kremer, H Telenius, J Theilmann, S Adam, E Starr, F Squitieri, B Lin, M A Kalchman. Nat Genet 1993
793
22

Long glutamine tracts cause nuclear localization of a novel form of huntingtin in medium spiny striatal neurons in HdhQ92 and HdhQ111 knock-in mice.
V C Wheeler, J K White, C A Gutekunst, V Vrbanac, M Weaver, X J Li, S H Li, H Yi, J P Vonsattel, J F Gusella,[...]. Hum Mol Genet 2000
337
20

Comprehensive behavioral and molecular characterization of a new knock-in mouse model of Huntington's disease: zQ175.
Liliana B Menalled, Andrea E Kudwa, Sam Miller, Jon Fitzpatrick, Judy Watson-Johnson, Nicole Keating, Melinda Ruiz, Richard Mushlin, William Alosio, Kristi McConnell,[...]. PLoS One 2012
215
20

Time course of early motor and neuropathological anomalies in a knock-in mouse model of Huntington's disease with 140 CAG repeats.
Liliana B Menalled, Jessica D Sison, Ioannis Dragatsis, Scott Zeitlin, Marie-Françoise Chesselet. J Comp Neurol 2003
322
20

Mismatch repair genes Mlh1 and Mlh3 modify CAG instability in Huntington's disease mice: genome-wide and candidate approaches.
Ricardo Mouro Pinto, Ella Dragileva, Andrew Kirby, Alejandro Lloret, Edith Lopez, Jason St Claire, Gagan B Panigrahi, Caixia Hou, Kim Holloway, Tammy Gillis,[...]. PLoS Genet 2013
112
20

Huntington disease.
J P Vonsattel, M DiFiglia. J Neuropathol Exp Neurol 1998
20

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain.
M DiFiglia, E Sapp, K O Chase, S W Davies, G P Bates, J P Vonsattel, N Aronin. Science 1997
19

Trinucleotide repeat length instability and age of onset in Huntington's disease.
M Duyao, C Ambrose, R Myers, A Novelletto, F Persichetti, M Frontali, S Folstein, C Ross, M Franz, M Abbott. Nat Genet 1993
806
19

Somatic expansion of the Huntington's disease CAG repeat in the brain is associated with an earlier age of disease onset.
Meera Swami, Audrey E Hendricks, Tammy Gillis, Tiffany Massood, Jayalakshmi Mysore, Richard H Myers, Vanessa C Wheeler. Hum Mol Genet 2009
159
19

A novel approach to investigate tissue-specific trinucleotide repeat instability.
Jong-Min Lee, Jie Zhang, Andrew I Su, John R Walker, Tim Wiltshire, Kihwa Kang, Ella Dragileva, Tammy Gillis, Edith T Lopez, Marie-Josee Boily,[...]. BMC Syst Biol 2010
68
26

A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration.
J G Hodgson, N Agopyan, C A Gutekunst, B R Leavitt, F LePiane, R Singaraja, D J Smith, N Bissada, K McCutcheon, J Nasir,[...]. Neuron 1999
623
18

Mismatch repair gene Msh2 modifies the timing of early disease in Hdh(Q111) striatum.
Vanessa C Wheeler, Lori-Anne Lebel, Vladimir Vrbanac, Allison Teed, Hein te Riele, Marcy E MacDonald. Hum Mol Genet 2003
158
18

Instability of highly expanded CAG repeats in mice transgenic for the Huntington's disease mutation.
L Mangiarini, K Sathasivam, A Mahal, R Mott, M Seller, G P Bates. Nat Genet 1997
247
18


Early phenotypes that presage late-onset neurodegenerative disease allow testing of modifiers in Hdh CAG knock-in mice.
Vanessa C Wheeler, Claire-Anne Gutekunst, Vladimir Vrbanac, Lori-Anne Lebel, Gabriele Schilling, Steven Hersch, Robert M Friedlander, James F Gusella, Jean-Paul Vonsattel, David R Borchelt,[...]. Hum Mol Genet 2002
132
17

Quantification of age-dependent somatic CAG repeat instability in Hdh CAG knock-in mice reveals different expansion dynamics in striatum and liver.
Jong-Min Lee, Ricardo Mouro Pinto, Tammy Gillis, Jason C St Claire, Vanessa C Wheeler. PLoS One 2011
39
43

Systematic behavioral evaluation of Huntington's disease transgenic and knock-in mouse models.
Liliana Menalled, Bassem F El-Khodor, Monica Patry, Mayte Suárez-Fariñas, Samantha J Orenstein, Benjamin Zahasky, Christina Leahy, Vanessa Wheeler, X William Yang, Marcy MacDonald,[...]. Neurobiol Dis 2009
221
15

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation.
S W Davies, M Turmaine, B A Cozens, M DiFiglia, A H Sharp, C A Ross, E Scherzinger, E E Wanker, L Mangiarini, G P Bates. Cell 1997
15

CAG repeat expansion in Huntington disease determines age at onset in a fully dominant fashion.
J-M Lee, E M Ramos, J-H Lee, T Gillis, J S Mysore, M R Hayden, S C Warby, P Morrison, M Nance, C A Ross,[...]. Neurology 2012
188
15

A Huntington's disease CAG expansion at the murine Hdh locus is unstable and associated with behavioural abnormalities in mice.
P F Shelbourne, N Killeen, R F Hevner, H M Johnston, L Tecott, M Lewandoski, M Ennis, L Ramirez, Z Li, C Iannicola,[...]. Hum Mol Genet 1999
190
15

Integrated genomics and proteomics define huntingtin CAG length-dependent networks in mice.
Peter Langfelder, Jeffrey P Cantle, Doxa Chatzopoulou, Nan Wang, Fuying Gao, Ismael Al-Ramahi, Xiao-Hong Lu, Eliana Marisa Ramos, Karla El-Zein, Yining Zhao,[...]. Nat Neurosci 2016
175
15

Marked differences in neurochemistry and aggregates despite similar behavioural and neuropathological features of Huntington disease in the full-length BACHD and YAC128 mice.
Mahmoud A Pouladi, Lisa M Stanek, Yuanyun Xie, Sonia Franciosi, Amber L Southwell, Yu Deng, Stefanie Butland, Weining Zhang, Seng H Cheng, Lamya S Shihabuddin,[...]. Hum Mol Genet 2012
99
14

Characterization of neurophysiological and behavioral changes, MRI brain volumetry and 1H MRS in zQ175 knock-in mouse model of Huntington's disease.
Taneli Heikkinen, Kimmo Lehtimäki, Nina Vartiainen, Jukka Puoliväli, Susan J Hendricks, Jack R Glaser, Amyaouch Bradaia, Kristian Wadel, Chrystelle Touller, Outi Kontkanen,[...]. PLoS One 2012
141
14


Triplet repeat mutation length gains correlate with cell-type specific vulnerability in Huntington disease brain.
Peggy F Shelbourne, Christine Keller-McGandy, Wenya Linda Bi, Song-Ro Yoon, Louis Dubeau, Nicola J Veitch, Jean Paul Vonsattel, Nancy S Wexler, Norman Arnheim, Sarah J Augood. Hum Mol Genet 2007
125
14

DNA instability in postmitotic neurons.
Roman Gonitel, Hilary Moffitt, Kirupa Sathasivam, Ben Woodman, Peter J Detloff, Richard L M Faull, Gillian P Bates. Proc Natl Acad Sci U S A 2008
132
14

Identification of genetic variants associated with Huntington's disease progression: a genome-wide association study.
Davina J Hensman Moss, Antonio F Pardiñas, Douglas Langbehn, Kitty Lo, Blair R Leavitt, Raymund Roos, Alexandra Durr, Simon Mead, Peter Holmans, Lesley Jones,[...]. Lancet Neurol 2017
129
14

Huntington's disease: can mice lead the way to treatment?
Zachary R Crook, David Housman. Neuron 2011
153
13

Molecular mechanisms and potential therapeutical targets in Huntington's disease.
Chiara Zuccato, Marta Valenza, Elena Cattaneo. Physiol Rev 2010
550
13

OGG1 initiates age-dependent CAG trinucleotide expansion in somatic cells.
Irina V Kovtun, Yuan Liu, Magnar Bjoras, Arne Klungland, Samuel H Wilson, Cynthia T McMurray. Nature 2007
324
13


MSH3 polymorphisms and protein levels affect CAG repeat instability in Huntington's disease mice.
Stéphanie Tomé, Kevin Manley, Jodie P Simard, Greg W Clark, Meghan M Slean, Meera Swami, Peggy F Shelbourne, Elisabeth R M Tillier, Darren G Monckton, Anne Messer,[...]. PLoS Genet 2013
82
14

Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease.
Kirupa Sathasivam, Andreas Neueder, Theresa A Gipson, Christian Landles, Agnesska C Benjamin, Marie K Bondulich, Donna L Smith, Richard L M Faull, Raymund A C Roos, David Howland,[...]. Proc Natl Acad Sci U S A 2013
264
12

Msh2 acts in medium-spiny striatal neurons as an enhancer of CAG instability and mutant huntingtin phenotypes in Huntington's disease knock-in mice.
Marina Kovalenko, Ella Dragileva, Jason St Claire, Tammy Gillis, Jolene R Guide, Jaclyn New, Hualing Dong, Raju Kucherlapati, Melanie H Kucherlapati, Michelle E Ehrlich,[...]. PLoS One 2012
43
27

Genetic background modifies nuclear mutant huntingtin accumulation and HD CAG repeat instability in Huntington's disease knock-in mice.
Alejandro Lloret, Ella Dragileva, Allison Teed, Janice Espinola, Elisa Fossale, Tammy Gillis, Edith Lopez, Richard H Myers, Marcy E MacDonald, Vanessa C Wheeler. Hum Mol Genet 2006
63
19


Huntington disease.
Gillian P Bates, Ray Dorsey, James F Gusella, Michael R Hayden, Chris Kay, Blair R Leavitt, Martha Nance, Christopher A Ross, Rachael I Scahill, Ronald Wetzel,[...]. Nat Rev Dis Primers 2015
558
12

Evidence for more widespread cerebral pathology in early HD: an MRI-based morphometric analysis.
H D Rosas, W J Koroshetz, Y I Chen, C Skeuse, M Vangel, M E Cudkowicz, K Caplan, K Marek, L J Seidman, N Makris,[...]. Neurology 2003
366
11

Paradoxical delay in the onset of disease caused by super-long CAG repeat expansions in R6/2 mice.
A Jennifer Morton, Dervila Glynn, Wendy Leavens, Zhiguang Zheng, Richard L M Faull, Jeremy N Skepper, James M Wight. Neurobiol Dis 2009
95
11

Longitudinal evaluation of the Hdh(CAG)150 knock-in murine model of Huntington's disease.
Mary Y Heng, Sara J Tallaksen-Greene, Peter J Detloff, Roger L Albin. J Neurosci 2007
103
11


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.