H Miyoshi, K A Smith, D E Mosier, I M Verma, B E Torbett. Science 1999
Times Cited: 529
Times Cited: 529
Times Cited
Times Co-cited
Similarity
In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector.
L Naldini, U Blömer, P Gallay, D Ory, R Mulligan, F H Gage, I M Verma, D Trono. Science 1996
L Naldini, U Blömer, P Gallay, D Ory, R Mulligan, F H Gage, I M Verma, D Trono. Science 1996
39
Hematopoietic stem cell gene therapy with a lentiviral vector in X-linked adrenoleukodystrophy.
Nathalie Cartier, Salima Hacein-Bey-Abina, Cynthia C Bartholomae, Gabor Veres, Manfred Schmidt, Ina Kutschera, Michel Vidaud, Ulrich Abel, Liliane Dal-Cortivo, Laure Caccavelli,[...]. Science 2009
Nathalie Cartier, Salima Hacein-Bey-Abina, Cynthia C Bartholomae, Gabor Veres, Manfred Schmidt, Ina Kutschera, Michel Vidaud, Ulrich Abel, Liliane Dal-Cortivo, Laure Caccavelli,[...]. Science 2009
24
Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1.
Salima Hacein-Bey-Abina, Alexandrine Garrigue, Gary P Wang, Jean Soulier, Annick Lim, Estelle Morillon, Emmanuelle Clappier, Laure Caccavelli, Eric Delabesse, Kheira Beldjord,[...]. J Clin Invest 2008
Salima Hacein-Bey-Abina, Alexandrine Garrigue, Gary P Wang, Jean Soulier, Annick Lim, Estelle Morillon, Emmanuelle Clappier, Laure Caccavelli, Eric Delabesse, Kheira Beldjord,[...]. J Clin Invest 2008
21
Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease.
M Cavazzana-Calvo, S Hacein-Bey, G de Saint Basile, F Gross, E Yvon, P Nusbaum, F Selz, C Hue, S Certain, J L Casanova,[...]. Science 2000
M Cavazzana-Calvo, S Hacein-Bey, G de Saint Basile, F Gross, E Yvon, P Nusbaum, F Selz, C Hue, S Certain, J L Casanova,[...]. Science 2000
20
LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1.
S Hacein-Bey-Abina, C Von Kalle, M Schmidt, M P McCormack, N Wulffraat, P Leboulch, A Lim, C S Osborne, R Pawliuk, E Morillon,[...]. Science 2003
S Hacein-Bey-Abina, C Von Kalle, M Schmidt, M P McCormack, N Wulffraat, P Leboulch, A Lim, C S Osborne, R Pawliuk, E Morillon,[...]. Science 2003
20
Stable transduction of quiescent CD34(+)CD38(-) human hematopoietic cells by HIV-1-based lentiviral vectors.
S S Case, M A Price, C T Jordan, X J Yu, L Wang, G Bauer, D L Haas, D Xu, R Stripecke, L Naldini,[...]. Proc Natl Acad Sci U S A 1999
S S Case, M A Price, C T Jordan, X J Yu, L Wang, G Bauer, D L Haas, D Xu, R Stripecke, L Naldini,[...]. Proc Natl Acad Sci U S A 1999
19
Hematopoietic stem cell gene transfer in a tumor-prone mouse model uncovers low genotoxicity of lentiviral vector integration.
Eugenio Montini, Daniela Cesana, Manfred Schmidt, Francesca Sanvito, Maurilio Ponzoni, Cynthia Bartholomae, Lucia Sergi Sergi, Fabrizio Benedicenti, Alessandro Ambrosi, Clelia Di Serio,[...]. Nat Biotechnol 2006
Eugenio Montini, Daniela Cesana, Manfred Schmidt, Francesca Sanvito, Maurilio Ponzoni, Cynthia Bartholomae, Lucia Sergi Sergi, Fabrizio Benedicenti, Alessandro Ambrosi, Clelia Di Serio,[...]. Nat Biotechnol 2006
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A third-generation lentivirus vector with a conditional packaging system.
T Dull, R Zufferey, M Kelly, R J Mandel, M Nguyen, D Trono, L Naldini. J Virol 1998
T Dull, R Zufferey, M Kelly, R J Mandel, M Nguyen, D Trono, L Naldini. J Virol 1998
16
The genotoxic potential of retroviral vectors is strongly modulated by vector design and integration site selection in a mouse model of HSC gene therapy.
Eugenio Montini, Daniela Cesana, Manfred Schmidt, Francesca Sanvito, Cynthia C Bartholomae, Marco Ranzani, Fabrizio Benedicenti, Lucia Sergi Sergi, Alessandro Ambrosi, Maurilio Ponzoni,[...]. J Clin Invest 2009
Eugenio Montini, Daniela Cesana, Manfred Schmidt, Francesca Sanvito, Cynthia C Bartholomae, Marco Ranzani, Fabrizio Benedicenti, Lucia Sergi Sergi, Alessandro Ambrosi, Maurilio Ponzoni,[...]. J Clin Invest 2009
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Therapeutic haemoglobin synthesis in beta-thalassaemic mice expressing lentivirus-encoded human beta-globin.
C May, S Rivella, J Callegari, G Heller, K M Gaensler, L Luzzatto, M Sadelain. Nature 2000
C May, S Rivella, J Callegari, G Heller, K M Gaensler, L Luzzatto, M Sadelain. Nature 2000
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HIV-1 integration in the human genome favors active genes and local hotspots.
Astrid R W Schröder, Paul Shinn, Huaming Chen, Charles Berry, Joseph R Ecker, Frederic Bushman. Cell 2002
Astrid R W Schröder, Paul Shinn, Huaming Chen, Charles Berry, Joseph R Ecker, Frederic Bushman. Cell 2002
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Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery.
R Zufferey, T Dull, R J Mandel, A Bukovsky, D Quiroz, L Naldini, D Trono. J Virol 1998
R Zufferey, T Dull, R J Mandel, A Bukovsky, D Quiroz, L Naldini, D Trono. J Virol 1998
15
Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1.
Marion G Ott, Manfred Schmidt, Kerstin Schwarzwaelder, Stefan Stein, Ulrich Siler, Ulrike Koehl, Hanno Glimm, Klaus Kühlcke, Andrea Schilz, Hana Kunkel,[...]. Nat Med 2006
Marion G Ott, Manfred Schmidt, Kerstin Schwarzwaelder, Stefan Stein, Ulrich Siler, Ulrike Koehl, Hanno Glimm, Klaus Kühlcke, Andrea Schilz, Hana Kunkel,[...]. Nat Med 2006
14
Transcription start regions in the human genome are favored targets for MLV integration.
Xiaolin Wu, Yuan Li, Bruce Crise, Shawn M Burgess. Science 2003
Xiaolin Wu, Yuan Li, Bruce Crise, Shawn M Burgess. Science 2003
13
Gene therapy of X-linked severe combined immunodeficiency by use of a pseudotyped gammaretroviral vector.
H Bobby Gaspar, Kathryn L Parsley, Steven Howe, Doug King, Kimberly C Gilmour, Joanna Sinclair, Gaby Brouns, Manfred Schmidt, Christof Von Kalle, Torben Barington,[...]. Lancet 2004
H Bobby Gaspar, Kathryn L Parsley, Steven Howe, Doug King, Kimberly C Gilmour, Joanna Sinclair, Gaby Brouns, Manfred Schmidt, Christof Von Kalle, Torben Barington,[...]. Lancet 2004
12
Transfusion independence and HMGA2 activation after gene therapy of human β-thalassaemia.
Marina Cavazzana-Calvo, Emmanuel Payen, Olivier Negre, Gary Wang, Kathleen Hehir, Floriane Fusil, Julian Down, Maria Denaro, Troy Brady, Karen Westerman,[...]. Nature 2010
Marina Cavazzana-Calvo, Emmanuel Payen, Olivier Negre, Gary Wang, Kathleen Hehir, Floriane Fusil, Julian Down, Maria Denaro, Troy Brady, Karen Westerman,[...]. Nature 2010
12
Gene therapy for immunodeficiency due to adenosine deaminase deficiency.
Alessandro Aiuti, Federica Cattaneo, Stefania Galimberti, Ulrike Benninghoff, Barbara Cassani, Luciano Callegaro, Samantha Scaramuzza, Grazia Andolfi, Massimiliano Mirolo, Immacolata Brigida,[...]. N Engl J Med 2009
Alessandro Aiuti, Federica Cattaneo, Stefania Galimberti, Ulrike Benninghoff, Barbara Cassani, Luciano Callegaro, Samantha Scaramuzza, Grazia Andolfi, Massimiliano Mirolo, Immacolata Brigida,[...]. N Engl J Med 2009
11
Sustained expression of genes delivered directly into liver and muscle by lentiviral vectors.
T Kafri, U Blömer, D A Peterson, F H Gage, I M Verma. Nat Genet 1997
T Kafri, U Blömer, D A Peterson, F H Gage, I M Verma. Nat Genet 1997
10
Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo.
R Zufferey, D Nagy, R J Mandel, L Naldini, D Trono. Nat Biotechnol 1997
R Zufferey, D Nagy, R J Mandel, L Naldini, D Trono. Nat Biotechnol 1997
10
Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector.
L Naldini, U Blömer, F H Gage, D Trono, I M Verma. Proc Natl Acad Sci U S A 1996
L Naldini, U Blömer, F H Gage, D Trono, I M Verma. Proc Natl Acad Sci U S A 1996
10
Transduction of human CD34+ CD38- bone marrow and cord blood-derived SCID-repopulating cells with third-generation lentiviral vectors.
G Guenechea, O I Gan, T Inamitsu, C Dorrell, D S Pereira, M Kelly, L Naldini, J E Dick. Mol Ther 2000
G Guenechea, O I Gan, T Inamitsu, C Dorrell, D S Pereira, M Kelly, L Naldini, J E Dick. Mol Ther 2000
10
HIV, but not murine leukemia virus, vectors mediate high efficiency gene transfer into freshly isolated G0/G1 human hematopoietic stem cells.
N Uchida, R E Sutton, A M Friera, D He, M J Reitsma, W C Chang, G Veres, R Scollay, I L Weissman. Proc Natl Acad Sci U S A 1998
N Uchida, R E Sutton, A M Friera, D He, M J Reitsma, W C Chang, G Veres, R Scollay, I L Weissman. Proc Natl Acad Sci U S A 1998
10
Correction of sickle cell disease in transgenic mouse models by gene therapy.
R Pawliuk, K A Westerman, M E Fabry, E Payen, R Tighe, E E Bouhassira, S A Acharya, J Ellis, I M London, C J Eaves,[...]. Science 2001
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10
Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy.
Alessandra Biffi, Eugenio Montini, Laura Lorioli, Martina Cesani, Francesca Fumagalli, Tiziana Plati, Cristina Baldoli, Sabata Martino, Andrea Calabria, Sabrina Canale,[...]. Science 2013
Alessandra Biffi, Eugenio Montini, Laura Lorioli, Martina Cesani, Francesca Fumagalli, Tiziana Plati, Cristina Baldoli, Sabata Martino, Andrea Calabria, Sabrina Canale,[...]. Science 2013
10
Lentiviral hematopoietic stem cell gene therapy in patients with Wiskott-Aldrich syndrome.
Alessandro Aiuti, Luca Biasco, Samantha Scaramuzza, Francesca Ferrua, Maria Pia Cicalese, Cristina Baricordi, Francesca Dionisio, Andrea Calabria, Stefania Giannelli, Maria Carmina Castiello,[...]. Science 2013
Alessandro Aiuti, Luca Biasco, Samantha Scaramuzza, Francesca Ferrua, Maria Pia Cicalese, Cristina Baricordi, Francesca Dionisio, Andrea Calabria, Stefania Giannelli, Maria Carmina Castiello,[...]. Science 2013
10
Correction of ADA-SCID by stem cell gene therapy combined with nonmyeloablative conditioning.
Alessandro Aiuti, Shimon Slavin, Memet Aker, Francesca Ficara, Sara Deola, Alessandra Mortellaro, Shoshana Morecki, Grazia Andolfi, Antonella Tabucchi, Filippo Carlucci,[...]. Science 2002
Alessandro Aiuti, Shimon Slavin, Memet Aker, Francesca Ficara, Sara Deola, Alessandra Mortellaro, Shoshana Morecki, Grazia Andolfi, Antonella Tabucchi, Filippo Carlucci,[...]. Science 2002
9
A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency.
Salima Hacein-Bey-Abina, Christof von Kalle, Manfred Schmidt, Françoise Le Deist, Nicolas Wulffraat, Elisabeth McIntyre, Isabelle Radford, Jean-Luc Villeval, Christopher C Fraser, Marina Cavazzana-Calvo,[...]. N Engl J Med 2003
Salima Hacein-Bey-Abina, Christof von Kalle, Manfred Schmidt, Françoise Le Deist, Nicolas Wulffraat, Elisabeth McIntyre, Isabelle Radford, Jean-Luc Villeval, Christopher C Fraser, Marina Cavazzana-Calvo,[...]. N Engl J Med 2003
9
Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients.
Steven J Howe, Marc R Mansour, Kerstin Schwarzwaelder, Cynthia Bartholomae, Michael Hubank, Helena Kempski, Martijn H Brugman, Karin Pike-Overzet, Stephen J Chatters, Dick de Ridder,[...]. J Clin Invest 2008
Steven J Howe, Marc R Mansour, Kerstin Schwarzwaelder, Cynthia Bartholomae, Michael Hubank, Helena Kempski, Martijn H Brugman, Karin Pike-Overzet, Stephen J Chatters, Dick de Ridder,[...]. J Clin Invest 2008
9
Sustained correction of X-linked severe combined immunodeficiency by ex vivo gene therapy.
Salima Hacein-Bey-Abina, Françoise Le Deist, Frédérique Carlier, Cécile Bouneaud, Christophe Hue, Jean-Pierre De Villartay, Adrian J Thrasher, Nicolas Wulffraat, Ricardo Sorensen, Sophie Dupuis-Girod,[...]. N Engl J Med 2002
Salima Hacein-Bey-Abina, Françoise Le Deist, Frédérique Carlier, Cécile Bouneaud, Christophe Hue, Jean-Pierre De Villartay, Adrian J Thrasher, Nicolas Wulffraat, Ricardo Sorensen, Sophie Dupuis-Girod,[...]. N Engl J Med 2002
9
Development of a self-inactivating lentivirus vector.
H Miyoshi, U Blömer, M Takahashi, F H Gage, I M Verma. J Virol 1998
H Miyoshi, U Blömer, M Takahashi, F H Gage, I M Verma. J Virol 1998
9
Lentiviral vectors pseudotyped with a modified RD114 envelope glycoprotein show increased stability in sera and augmented transduction of primary lymphocytes and CD34+ cells derived from human and nonhuman primates.
Virginie Sandrin, Bertrand Boson, Patrick Salmon, Wilfried Gay, Didier Nègre, Roger Le Grand, Didier Trono, François-Loïc Cosset. Blood 2002
Virginie Sandrin, Bertrand Boson, Patrick Salmon, Wilfried Gay, Didier Nègre, Roger Le Grand, Didier Trono, François-Loïc Cosset. Blood 2002
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Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery.
Angelo Lombardo, Pietro Genovese, Christian M Beausejour, Silvia Colleoni, Ya-Li Lee, Kenneth A Kim, Dale Ando, Fyodor D Urnov, Cesare Galli, Philip D Gregory,[...]. Nat Biotechnol 2007
Angelo Lombardo, Pietro Genovese, Christian M Beausejour, Silvia Colleoni, Ya-Li Lee, Kenneth A Kim, Dale Ando, Fyodor D Urnov, Cesare Galli, Philip D Gregory,[...]. Nat Biotechnol 2007
8
Gene transfer in humans using a conditionally replicating lentiviral vector.
Bruce L Levine, Laurent M Humeau, Jean Boyer, Rob-Roy MacGregor, Tessio Rebello, Xiaobin Lu, Gwendolyn K Binder, Vladimir Slepushkin, Franck Lemiale, John R Mascola,[...]. Proc Natl Acad Sci U S A 2006
Bruce L Levine, Laurent M Humeau, Jean Boyer, Rob-Roy MacGregor, Tessio Rebello, Xiaobin Lu, Gwendolyn K Binder, Vladimir Slepushkin, Franck Lemiale, John R Mascola,[...]. Proc Natl Acad Sci U S A 2006
8
Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo.
Nathalia Holt, Jianbin Wang, Kenneth Kim, Geoffrey Friedman, Xingchao Wang, Vanessa Taupin, Gay M Crooks, Donald B Kohn, Philip D Gregory, Michael C Holmes,[...]. Nat Biotechnol 2010
Nathalia Holt, Jianbin Wang, Kenneth Kim, Geoffrey Friedman, Xingchao Wang, Vanessa Taupin, Gay M Crooks, Donald B Kohn, Philip D Gregory, Michael C Holmes,[...]. Nat Biotechnol 2010
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Colocalization of retrovirus and target cells on specific fibronectin fragments increases genetic transduction of mammalian cells.
H Hanenberg, X L Xiao, D Dilloo, K Hashino, I Kato, D A Williams. Nat Med 1996
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7
Hot spots of retroviral integration in human CD34+ hematopoietic cells.
Claudia Cattoglio, Giulia Facchini, Daniela Sartori, Antonella Antonelli, Annarita Miccio, Barbara Cassani, Manfred Schmidt, Christof von Kalle, Steve Howe, Adrian J Thrasher,[...]. Blood 2007
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Systematic determination of the packaging limit of lentiviral vectors.
M Kumar, B Keller, N Makalou, R E Sutton. Hum Gene Ther 2001
M Kumar, B Keller, N Makalou, R E Sutton. Hum Gene Ther 2001
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Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors.
R Zufferey, J E Donello, D Trono, T J Hope. J Virol 1999
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Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5.
Xiao-Feng Qin, Dong Sung An, Irvin S Y Chen, David Baltimore. Proc Natl Acad Sci U S A 2003
Xiao-Feng Qin, Dong Sung An, Irvin S Y Chen, David Baltimore. Proc Natl Acad Sci U S A 2003
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Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation.
Gero Hütter, Daniel Nowak, Maximilian Mossner, Susanne Ganepola, Arne Müssig, Kristina Allers, Thomas Schneider, Jörg Hofmann, Claudia Kücherer, Olga Blau,[...]. N Engl J Med 2009
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Insertional transformation of hematopoietic cells by self-inactivating lentiviral and gammaretroviral vectors.
Ute Modlich, Susana Navarro, Daniela Zychlinski, Tobias Maetzig, Sabine Knoess, Martijn H Brugman, Axel Schambach, Sabine Charrier, Anne Galy, Adrian J Thrasher,[...]. Mol Ther 2009
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Physiological promoters reduce the genotoxic risk of integrating gene vectors.
Daniela Zychlinski, Axel Schambach, Ute Modlich, Tobias Maetzig, Johann Meyer, Elke Grassman, Anjali Mishra, Christopher Baum. Mol Ther 2008
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Genomic instability and myelodysplasia with monosomy 7 consequent to EVI1 activation after gene therapy for chronic granulomatous disease.
Stefan Stein, Marion G Ott, Stephan Schultze-Strasser, Anna Jauch, Barbara Burwinkel, Andrea Kinner, Manfred Schmidt, Alwin Krämer, Joachim Schwäble, Hanno Glimm,[...]. Nat Med 2010
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Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeutics.
M A Kay, J C Glorioso, L Naldini. Nat Med 2001
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Transduction of human progenitor hematopoietic stem cells by human immunodeficiency virus type 1-based vectors is cell cycle dependent.
R E Sutton, M J Reitsma, N Uchida, P O Brown. J Virol 1999
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Murine leukemia induced by retroviral gene marking.
Zhixiong Li, Jochen Düllmann, Bernd Schiedlmeier, Manfred Schmidt, Christof von Kalle, Johann Meyer, Martin Forster, Carol Stocking, Anke Wahlers, Oliver Frank,[...]. Science 2002
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A nuclear localization signal within HIV-1 matrix protein that governs infection of non-dividing cells.
M I Bukrinsky, S Haggerty, M P Dempsey, N Sharova, A Adzhubel, L Spitz, P Lewis, D Goldfarb, M Emerman, M Stevenson. Nature 1993
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Cell-culture assays reveal the importance of retroviral vector design for insertional genotoxicity.
Ute Modlich, Jens Bohne, Manfred Schmidt, Christof von Kalle, Sabine Knöss, Axel Schambach, Christopher Baum. Blood 2006
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Distinct genomic integration of MLV and SIV vectors in primate hematopoietic stem and progenitor cells.
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T lymphocyte-directed gene therapy for ADA- SCID: initial trial results after 4 years.
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6
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.