A citation-based method for searching scientific literature

T Hofmann, A G Obukhov, M Schaefer, C Harteneck, T Gudermann, G Schultz. Nature 1999
Times Cited: 1140







List of co-cited articles
1255 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Structure of the receptor-activated human TRPC6 and TRPC3 ion channels.
Qinglin Tang, Wenjun Guo, Li Zheng, Jing-Xiang Wu, Meng Liu, Xindi Zhou, Xiaolin Zhang, Lei Chen. Cell Res 2018
74
31

A mutation in the TRPC6 cation channel causes familial focal segmental glomerulosclerosis.
Michelle P Winn, Peter J Conlon, Kelvin L Lynn, Merry Kay Farrington, Tony Creazzo, April F Hawkins, Nikki Daskalakis, Shu Ying Kwan, Seth Ebersviller, James L Burchette,[...]. Science 2005
754
23

Dynamic NHERF interaction with TRPC4/5 proteins is required for channel gating by diacylglycerol.
Ursula Storch, Anna-Lena Forst, Franziska Pardatscher, Serap Erdogmus, Maximilian Philipp, Manuel Gregoritza, Michael Mederos Y Schnitzler, Thomas Gudermann. Proc Natl Acad Sci U S A 2017
58
32

A common mechanism underlies stretch activation and receptor activation of TRPC6 channels.
Maria A Spassova, Thamara Hewavitharana, Wen Xu, Jonathan Soboloff, Donald L Gill. Proc Natl Acad Sci U S A 2006
305
17

TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function.
Jochen Reiser, Krishna R Polu, Clemens C Möller, Peter Kenlan, Mehmet M Altintas, Changli Wei, Christian Faul, Stephanie Herbert, Ivan Villegas, Carmen Avila-Casado,[...]. Nat Genet 2005
579
16

Identification and Validation of Larixyl Acetate as a Potent TRPC6 Inhibitor.
Nicole Urban, Liming Wang, Sandra Kwiek, Jörg Rademann, Wolfgang M Kuebler, Michael Schaefer. Mol Pharmacol 2016
44
36

Combined TRPC3 and TRPC6 blockade by selective small-molecule or genetic deletion inhibits pathological cardiac hypertrophy.
Kinya Seo, Peter P Rainer, Virginia Shalkey Hahn, Dong-Ik Lee, Su-Hyun Jo, Asger Andersen, Ting Liu, Xiaoping Xu, Robert N Willette, John J Lepore,[...]. Proc Natl Acad Sci U S A 2014
108
16

Selective and direct inhibition of TRPC3 channels underlies biological activities of a pyrazole compound.
Shigeki Kiyonaka, Kenta Kato, Motohiro Nishida, Kazuhiro Mio, Takuro Numaga, Yuichi Sawaguchi, Takashi Yoshida, Minoru Wakamori, Emiko Mori, Tomohiro Numata,[...]. Proc Natl Acad Sci U S A 2009
261
16

Increased vascular smooth muscle contractility in TRPC6-/- mice.
Alexander Dietrich, Michael Mederos Y Schnitzler, Maik Gollasch, Volkmar Gross, Ursula Storch, Galyna Dubrovska, Michael Obst, Eda Yildirim, Birgit Salanova, Hermann Kalwa,[...]. Mol Cell Biol 2005
375
16

Discovery and pharmacological characterization of a novel potent inhibitor of diacylglycerol-sensitive TRPC cation channels.
T Maier, M Follmann, G Hessler, H-W Kleemann, S Hachtel, B Fuchs, N Weissmann, W Linz, T Schmidt, M Löhn,[...]. Br J Pharmacol 2015
59
25

TRP channels as cellular sensors.
David E Clapham. Nature 2003
15

Cryo-EM structure of the cytoplasmic domain of murine transient receptor potential cation channel subfamily C member 6 (TRPC6).
Caleigh M Azumaya, Francisco Sierra-Valdez, Julio F Cordero-Morales, Terunaga Nakagawa. J Biol Chem 2018
23
65

In vivo selective inhibition of TRPC6 by antagonist BI 749327 ameliorates fibrosis and dysfunction in cardiac and renal disease.
Brian Leei Lin, Damian Matera, Julia F Doerner, Nan Zheng, Donato Del Camino, Sumita Mishra, Hong Bian, Svetlana Zeveleva, Xiaoguang Zhen, Nathaniel T Blair,[...]. Proc Natl Acad Sci U S A 2019
32
46

TRPC channels are necessary mediators of pathologic cardiac hypertrophy.
Xu Wu, Petra Eder, Baojun Chang, Jeffery D Molkentin. Proc Natl Acad Sci U S A 2010
194
14

TRPC6 fulfills a calcineurin signaling circuit during pathologic cardiac remodeling.
Koichiro Kuwahara, Yanggan Wang, John McAnally, James A Richardson, Rhonda Bassel-Duby, Joseph A Hill, Eric N Olson. J Clin Invest 2006
382
13

TRPC1, a human homolog of a Drosophila store-operated channel.
P D Wes, J Chevesich, A Jeromin, C Rosenberg, G Stetten, C Montell. Proc Natl Acad Sci U S A 1995
467
13

Structure of the human lipid-gated cation channel TRPC3.
Chen Fan, Wooyoung Choi, Weinan Sun, Juan Du, Wei Lü. Elife 2018
54
22

Subunit composition of mammalian transient receptor potential channels in living cells.
Thomas Hofmann, Michael Schaefer, Günter Schultz, Thomas Gudermann. Proc Natl Acad Sci U S A 2002
571
12

Electron cryo-microscopy structure of the canonical TRPC4 ion channel.
Deivanayagabarathy Vinayagam, Thomas Mager, Amir Apelbaum, Arne Bothe, Felipe Merino, Oliver Hofnagel, Christos Gatsogiannis, Stefan Raunser. Elife 2018
60
20

An optically controlled probe identifies lipid-gating fenestrations within the TRPC3 channel.
Michaela Lichtenegger, Oleksandra Tiapko, Barbora Svobodova, Thomas Stockner, Toma N Glasnov, Wolfgang Schreibmayer, Dieter Platzer, Gema Guedes de la Cruz, Sarah Krenn, Romana Schober,[...]. Nat Chem Biol 2018
38
31

Structure of the mouse TRPC4 ion channel.
Jingjing Duan, Jian Li, Bo Zeng, Gui-Lan Chen, Xiaogang Peng, Yixing Zhang, Jianbin Wang, David E Clapham, Zongli Li, Jin Zhang. Nat Commun 2018
60
20

TRP channels.
Kartik Venkatachalam, Craig Montell. Annu Rev Biochem 2007
12

TRPC3 contributes to regulation of cardiac contractility and arrhythmogenesis by dynamic interaction with NCX1.
Bernhard Doleschal, Uwe Primessnig, Gerald Wölkart, Stefan Wolf, Michaela Schernthaner, Michaela Lichtenegger, Toma N Glasnov, C Oliver Kappe, Bernd Mayer, Gudrun Antoons,[...]. Cardiovasc Res 2015
48
22

TRPC3 and TRPC6 are essential for angiotensin II-induced cardiac hypertrophy.
Naoya Onohara, Motohiro Nishida, Ryuji Inoue, Hiroyuki Kobayashi, Hideki Sumimoto, Yoji Sato, Yasuo Mori, Taku Nagao, Hitoshi Kurose. EMBO J 2006
291
11

(-)-Englerin A is a potent and selective activator of TRPC4 and TRPC5 calcium channels.
Yasemin Akbulut, Hannah J Gaunt, Katsuhiko Muraki, Melanie J Ludlow, Mohamed S Amer, Alexander Bruns, Naveen S Vasudev, Lea Radtke, Matthieu Willot, Sven Hahn,[...]. Angew Chem Int Ed Engl 2015
115
11

TRPC channels: Structure, function, regulation and recent advances in small molecular probes.
Hongbo Wang, Xiaoding Cheng, Jinbin Tian, Yuling Xiao, Tian Tian, Fuchun Xu, Xuechuan Hong, Michael X Zhu. Pharmacol Ther 2020
43
25


TRPC6 G757D Loss-of-Function Mutation Associates with FSGS.
Marc Riehle, Anja K Büscher, Björn-Oliver Gohlke, Mario Kaßmann, Maria Kolatsi-Joannou, Jan H Bräsen, Mato Nagel, Jan U Becker, Paul Winyard, Peter F Hoyer,[...]. J Am Soc Nephrol 2016
55
18

Hyperforin--a key constituent of St. John's wort specifically activates TRPC6 channels.
Kristina Leuner, Victor Kazanski, Margarethe Müller, Kirill Essin, Bettina Henke, Maik Gollasch, Christian Harteneck, Walter E Müller. FASEB J 2007
152
10


A TRPC6-dependent pathway for myofibroblast transdifferentiation and wound healing in vivo.
Jennifer Davis, Adam R Burr, Gregory F Davis, Lutz Birnbaumer, Jeffery D Molkentin. Dev Cell 2012
205
10

Novel pyrazole compounds for pharmacological discrimination between receptor-operated and store-operated Ca(2+) entry pathways.
H Schleifer, B Doleschal, M Lichtenegger, R Oppenrieder, I Derler, I Frischauf, T N Glasnov, C O Kappe, C Romanin, K Groschner. Br J Pharmacol 2012
113
10

Galphaq-TRPC6-mediated Ca2+ entry induces RhoA activation and resultant endothelial cell shape change in response to thrombin.
Itender Singh, Nebojsa Knezevic, Gias U Ahmmed, Vidisha Kini, Asrar B Malik, Dolly Mehta. J Biol Chem 2007
163
10

Heteromeric channels formed by TRPC1, TRPC4 and TRPC5 define hippocampal synaptic transmission and working memory.
Jenny Bröker-Lai, Astrid Kollewe, Barbara Schindeldecker, Jörg Pohle, Vivan Nguyen Chi, Ilka Mathar, Raul Guzman, Yvonne Schwarz, Alan Lai, Petra Weißgerber,[...]. EMBO J 2017
64
15

trp, a novel mammalian gene family essential for agonist-activated capacitative Ca2+ entry.
X Zhu, M Jiang, M Peyton, G Boulay, R Hurst, E Stefani, L Birnbaumer. Cell 1996
571
10

TRPC1 forms the stretch-activated cation channel in vertebrate cells.
Rosario Maroto, Albert Raso, Thomas G Wood, Alex Kurosky, Boris Martinac, Owen P Hamill. Nat Cell Biol 2005
447
10

TRPC1 and TRPC5 form a novel cation channel in mammalian brain.
C Strübing, G Krapivinsky, L Krapivinsky, D E Clapham. Neuron 2001
586
10

Gq-coupled receptors as mechanosensors mediating myogenic vasoconstriction.
Michael Mederos y Schnitzler, Ursula Storch, Simone Meibers, Pascal Nurwakagari, Andreas Breit, Kirill Essin, Maik Gollasch, Thomas Gudermann. EMBO J 2008
220
10

Novel pharmacological TRPC inhibitors block hypoxia-induced vasoconstriction.
Nicole Urban, Kerstin Hill, Liming Wang, Wolfgang M Kuebler, Michael Schaefer. Cell Calcium 2012
55
16

Activation of TRPC6 channels is essential for lung ischaemia-reperfusion induced oedema in mice.
Norbert Weissmann, Akylbek Sydykov, Hermann Kalwa, Ursula Storch, Beate Fuchs, Michael Mederos y Schnitzler, Ralf P Brandes, Friedrich Grimminger, Marcel Meissner, Marc Freichel,[...]. Nat Commun 2012
130
9

Pyrazolopyrimidines as Potent Stimulators for Transient Receptor Potential Canonical 3/6/7 Channels.
Chunrong Qu, Mingmin Ding, Yingmin Zhu, Yungang Lu, Juan Du, Melissa Miller, Jinbin Tian, Jinmei Zhu, Jian Xu, Meng Wen,[...]. J Med Chem 2017
23
39

Transient receptor potential canonical-3 channel-dependent fibroblast regulation in atrial fibrillation.
Masahide Harada, Xiaobin Luo, Xiao Yan Qi, Artavazd Tadevosyan, Ange Maguy, Balazs Ordog, Jonathan Ledoux, Takeshi Kato, Patrice Naud, Niels Voigt,[...]. Circulation 2012
163
9

TRPC3-GEF-H1 axis mediates pressure overload-induced cardiac fibrosis.
Takuro Numaga-Tomita, Naoyuki Kitajima, Takuya Kuroda, Akiyuki Nishimura, Kei Miyano, Satoshi Yasuda, Koichiro Kuwahara, Yoji Sato, Tomomi Ide, Lutz Birnbaumer,[...]. Sci Rep 2016
35
25

A background Ca2+ entry pathway mediated by TRPC1/TRPC4 is critical for development of pathological cardiac remodelling.
Juan E Camacho Londoño, Qinghai Tian, Karin Hammer, Laura Schröder, Julia Camacho Londoño, Jan C Reil, Tao He, Martin Oberhofer, Stefanie Mannebach, Ilka Mathar,[...]. Eur Heart J 2015
67
13

TRPC3 channels are required for synaptic transmission and motor coordination.
Jana Hartmann, Elena Dragicevic, Helmuth Adelsberger, Horst A Henning, Martin Sumser, Joel Abramowitz, Robert Blum, Alexander Dietrich, Marc Freichel, Veit Flockerzi,[...]. Neuron 2008
284
9


A small-molecule inhibitor of TRPC5 ion channels suppresses progressive kidney disease in animal models.
Yiming Zhou, Philip Castonguay, Eriene-Heidi Sidhom, Abbe R Clark, Moran Dvela-Levitt, Sookyung Kim, Jonas Sieber, Nicolas Wieder, Ji Yong Jung, Svetlana Andreeva,[...]. Science 2017
74
12

Identification of ML204, a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels.
Melissa Miller, Jie Shi, Yingmin Zhu, Maksym Kustov, Jin-bin Tian, Amy Stevens, Meng Wu, Jia Xu, Shunyou Long, Pu Yang,[...]. J Biol Chem 2011
133
9

Revisiting TRPC1 and TRPC6 mechanosensitivity.
Philip Gottlieb, Joost Folgering, Rosario Maroto, Albert Raso, Thomas G Wood, Alex Kurosky, Charles Bowman, Delphine Bichet, Amanda Patel, Frederick Sachs,[...]. Pflugers Arch 2008
184
9

Transient receptor potential cation channels in disease.
Bernd Nilius, Grzegorz Owsianik, Thomas Voets, John A Peters. Physiol Rev 2007
971
9


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.