A citation-based method for searching scientific literature

K J Wu, C Grandori, M Amacker, N Simon-Vermot, A Polack, J Lingner, R Dalla-Favera. Nat Genet 1999
Times Cited: 699







List of co-cited articles
945 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Specific association of human telomerase activity with immortal cells and cancer.
N W Kim, M A Piatyszek, K R Prowse, C B Harley, M D West, P L Ho, G M Coviello, W E Wright, S L Weinrich, J W Shay. Science 1994
25

Highly recurrent TERT promoter mutations in human melanoma.
Franklin W Huang, Eran Hodis, Mary Jue Xu, Gregory V Kryukov, Lynda Chin, Levi A Garraway. Science 2013
25

TERT promoter mutations in familial and sporadic melanoma.
Susanne Horn, Adina Figl, P Sivaramakrishna Rachakonda, Christine Fischer, Antje Sucker, Andreas Gast, Stephanie Kadel, Iris Moll, Eduardo Nagore, Kari Hemminki,[...]. Science 2013
22

TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal.
Patrick J Killela, Zachary J Reitman, Yuchen Jiao, Chetan Bettegowda, Nishant Agrawal, Luis A Diaz, Allan H Friedman, Henry Friedman, Gary L Gallia, Beppino C Giovanella,[...]. Proc Natl Acad Sci U S A 2013
848
18

A survey of telomerase activity in human cancer.
J W Shay, S Bacchetti. Eur J Cancer 1997
18

Cancer. The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer.
Robert J A Bell, H Tomas Rube, Alex Kreig, Andrew Mancini, Shaun D Fouse, Raman P Nagarajan, Serah Choi, Chibo Hong, Daniel He, Melike Pekmezci,[...]. Science 2015
287
17

Sp1 cooperates with c-Myc to activate transcription of the human telomerase reverse transcriptase gene (hTERT).
S Kyo, M Takakura, T Taira, T Kanaya, H Itoh, M Yutsudo, H Ariga, M Inoue. Nucleic Acids Res 2000
391
16

Telomerase catalytic subunit homologs from fission yeast and human.
T M Nakamura, G B Morin, K B Chapman, S L Weinrich, W H Andrews, J Lingner, C B Harley, T R Cech. Science 1997
15


The RNA component of human telomerase.
J Feng, W D Funk, S S Wang, S L Weinrich, A A Avilion, C P Chiu, R R Adams, E Chang, R C Allsopp, J Yu. Science 1995
13

TERT promoter mutations in bladder cancer affect patient survival and disease recurrence through modification by a common polymorphism.
P Sivaramakrishna Rachakonda, Ismail Hosen, Petra J de Verdier, Mahdi Fallah, Barbara Heidenreich, Charlotta Ryk, N Peter Wiklund, Gunnar Steineck, Dirk Schadendorf, Kari Hemminki,[...]. Proc Natl Acad Sci U S A 2013
209
13

Hallmarks of cancer: the next generation.
Douglas Hanahan, Robert A Weinberg. Cell 2011
13


Cancer-associated TERT promoter mutations abrogate telomerase silencing.
Kunitoshi Chiba, Joshua Z Johnson, Jacob M Vogan, Tina Wagner, John M Boyle, Dirk Hockemeyer. Elife 2015
142
12

Extension of life-span by introduction of telomerase into normal human cells.
A G Bodnar, M Ouellette, M Frolkis, S E Holt, C P Chiu, G B Morin, C B Harley, J W Shay, S Lichtsteiner, W E Wright. Science 1998
12

Telomerase modulates Wnt signalling by association with target gene chromatin.
Jae-Il Park, Andrew S Venteicher, Ji Yeon Hong, Jinkuk Choi, Sohee Jun, Marina Shkreli, Woody Chang, Zhaojing Meng, Peggie Cheung, Hong Ji,[...]. Nature 2009
432
12

Telomerase regulates MYC-driven oncogenesis independent of its reverse transcriptase activity.
Cheryl M Koh, Ekta Khattar, Shi Chi Leow, Chia Yi Liu, Julius Muller, Wei Xia Ang, Yinghui Li, Guido Franzoso, Shang Li, Ernesto Guccione,[...]. J Clin Invest 2015
89
13

Frequency of TERT promoter mutations in human cancers.
João Vinagre, Ana Almeida, Helena Pópulo, Rui Batista, Joana Lyra, Vasco Pinto, Ricardo Coelho, Ricardo Celestino, Hugo Prazeres, Luis Lima,[...]. Nat Commun 2013
512
11

Telomerase directly regulates NF-κB-dependent transcription.
Arkasubhra Ghosh, Gaye Saginc, Shi Chi Leow, Ekta Khattar, Eun Myong Shin, Ting Dong Yan, Marc Wong, Zhizhuo Zhang, Guoliang Li, Wing-Kin Sung,[...]. Nat Cell Biol 2012
208
11

Human telomerase and its regulation.
Yu-Sheng Cong, Woodring E Wright, Jerry W Shay. Microbiol Mol Biol Rev 2002
586
11

Roles of telomeres and telomerase in cancer, and advances in telomerase-targeted therapies.
Mohammad A Jafri, Shakeel A Ansari, Mohammed H Alqahtani, Jerry W Shay. Genome Med 2016
212
11

Cancer. TERT promoter mutations and telomerase reactivation in urothelial cancer.
Sumit Borah, Linghe Xi, Arthur J Zaug, Natasha M Powell, Garrett M Dancik, Scott B Cohen, James C Costello, Dan Theodorescu, Thomas R Cech. Science 2015
190
10

Non-canonical NF-κB signalling and ETS1/2 cooperatively drive C250T mutant TERT promoter activation.
Yinghui Li, Qi-Ling Zhou, Wenjie Sun, Prashant Chandrasekharan, Hui Shan Cheng, Zhe Ying, Manikandan Lakshmanan, Anandhkumar Raju, Daniel G Tenen, Shi-Yuan Cheng,[...]. Nat Cell Biol 2015
117
10

Telomerase activation by genomic rearrangements in high-risk neuroblastoma.
Martin Peifer, Falk Hertwig, Frederik Roels, Daniel Dreidax, Moritz Gartlgruber, Roopika Menon, Andrea Krämer, Justin L Roncaioli, Frederik Sand, Johannes M Heuckmann,[...]. Nature 2015
266
10

Mutation of the TERT promoter, switch to active chromatin, and monoallelic TERT expression in multiple cancers.
Josh Lewis Stern, Dan Theodorescu, Bert Vogelstein, Nickolas Papadopoulos, Thomas R Cech. Genes Dev 2015
97
10

Telomerase activity in human germline and embryonic tissues and cells.
W E Wright, M A Piatyszek, W E Rainey, W Byrd, J W Shay. Dev Genet 1996
951
9

Function of AP-1 in transcription of the telomerase reverse transcriptase gene (TERT) in human and mouse cells.
Masahiro Takakura, Satoru Kyo, Masaki Inoue, Woodring E Wright, Jerry W Shay. Mol Cell Biol 2005
90
10

Ets2 maintains hTERT gene expression and breast cancer cell proliferation by interacting with c-Myc.
Dakang Xu, Julie Dwyer, He Li, Wei Duan, Jun-Ping Liu. J Biol Chem 2008
101
9



Regulation of the human catalytic subunit of telomerase (hTERT).
Michael Daniel, Gregory W Peek, Trygve O Tollefsbol. Gene 2012
170
9

The telomerase reverse transcriptase regulates chromatin state and DNA damage responses.
Kenkichi Masutomi, Richard Possemato, Judy M Y Wong, Jennifer L Currier, Zuzana Tothova, Judith B Manola, Shridar Ganesan, Peter M Lansdorp, Kathleen Collins, William C Hahn. Proc Natl Acad Sci U S A 2005
253
9

hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization.
M Meyerson, C M Counter, E N Eaton, L W Ellisen, P Steiner, S D Caddle, L Ziaugra, R L Beijersbergen, M J Davidoff, Q Liu,[...]. Cell 1997
9

Telomerase reverse transcriptase gene is a direct target of c-Myc but is not functionally equivalent in cellular transformation.
R A Greenberg, R C O'Hagan, H Deng, Q Xiao, S R Hann, R R Adams, S Lichtsteiner, L Chin, G B Morin, R A DePinho. Oncogene 1999
337
9

High frequency of telomerase reverse-transcriptase promoter somatic mutations in hepatocellular carcinoma and preneoplastic lesions.
Jean Charles Nault, Maxime Mallet, Camilla Pilati, Julien Calderaro, Paulette Bioulac-Sage, Christophe Laurent, Alexis Laurent, Daniel Cherqui, Charles Balabaud, Jessica Zucman-Rossi. Nat Commun 2013
364
9

TERT rearrangements are frequent in neuroblastoma and identify aggressive tumors.
Linda J Valentijn, Jan Koster, Danny A Zwijnenburg, Nancy E Hasselt, Peter van Sluis, Richard Volckmann, Max M van Noesel, Rani E George, Godelieve A M Tytgat, Jan J Molenaar,[...]. Nat Genet 2015
184
9

Systematic analysis of telomere length and somatic alterations in 31 cancer types.
Floris P Barthel, Wei Wei, Ming Tang, Emmanuel Martinez-Ledesma, Xin Hu, Samirkumar B Amin, Kadir C Akdemir, Sahil Seth, Xingzhi Song, Qianghu Wang,[...]. Nat Genet 2017
201
9

Transcription Regulation of the Human Telomerase Reverse Transcriptase (hTERT) Gene.
Muhammad Khairul Ramlee, Jing Wang, Wei Xun Toh, Shang Li. Genes (Basel) 2016
70
12

Hypermethylation of the human telomerase catalytic subunit (hTERT) gene correlates with telomerase activity.
Isabelle Guilleret, Pu Yan, Fabienne Grange, Richard Braunschweig, Fred T Bosman, Jean Benhattar. Int J Cancer 2002
173
8

Dual roles of c-Myc in the regulation of hTERT gene.
Yuanjun Zhao, De Cheng, Shuwen Wang, Jiyue Zhu. Nucleic Acids Res 2014
40
20

Understanding and exploiting hTERT promoter regulation for diagnosis and treatment of human cancers.
Satoru Kyo, Masahiro Takakura, Toshiyoshi Fujiwara, Masaki Inoue. Cancer Sci 2008
243
8

Mitochondrial telomerase protects cancer cells from nuclear DNA damage and apoptosis.
Chatchawan Singhapol, Deepali Pal, Rafal Czapiewski, Mahendar Porika, Glyn Nelson, Gabriele C Saretzki. PLoS One 2013
93
8

A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes.
R K Moyzis, J M Buckingham, L S Cram, M Dani, L L Deaven, M D Jones, J Meyne, R L Ratliff, J R Wu. Proc Natl Acad Sci U S A 1988
8

Isolation of a candidate human telomerase catalytic subunit gene, which reveals complex splicing patterns in different cell types.
A Kilian, D D Bowtell, H E Abud, G R Hime, D J Venter, P K Keese, E L Duncan, R R Reddel, R A Jefferson. Hum Mol Genet 1997
496
8

Mitochondrial telomerase reverse transcriptase binds to and protects mitochondrial DNA and function from damage.
Judith Haendeler, Stefan Dröse, Nicole Büchner, Sascha Jakob, Joachim Altschmied, Christine Goy, Ioakim Spyridopoulos, Andreas M Zeiher, Ulrich Brandt, Stefanie Dimmeler. Arterioscler Thromb Vasc Biol 2009
192
8

Telomerase does not counteract telomere shortening but protects mitochondrial function under oxidative stress.
Shaheda Ahmed, João F Passos, Matthew J Birket, Tina Beckmann, Sebastian Brings, Heiko Peters, Mark A Birch-Machin, Thomas von Zglinicki, Gabriele Saretzki. J Cell Sci 2008
273
8

Wnt/β-catenin signaling regulates telomerase in stem cells and cancer cells.
Katrin Hoffmeyer, Angelo Raggioli, Stefan Rudloff, Roman Anton, Andreas Hierholzer, Ignacio Del Valle, Kerstin Hein, Riana Vogt, Rolf Kemler. Science 2012
344
8


Methylation of the TERT promoter and risk stratification of childhood brain tumours: an integrative genomic and molecular study.
Pedro Castelo-Branco, Sanaa Choufani, Stephen Mack, Denis Gallagher, Cindy Zhang, Tatiana Lipman, Nataliya Zhukova, Erin J Walker, Dianna Martin, Diana Merino,[...]. Lancet Oncol 2013
148
8

Myc activates telomerase.
J Wang, L Y Xie, S Allan, D Beach, G J Hannon. Genes Dev 1998
532
8


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.