A citation-based method for searching scientific literature

TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques.
Yaming Wang, Tyler K Ulland, Jason D Ulrich, Wilbur Song, John A Tzaferis, Justin T Hole, Peng Yuan, Thomas E Mahan, Yang Shi, Susan Gilfillan, Marina Cella, Jaime Grutzendler, Ronald B DeMattos, John R Cirrito, David M Holtzman, Marco Colonna. J Exp Med 2016
Times Cited: 401



TREM2 deficiency attenuates neuroinflammation and protects against neurodegeneration in a mouse model of tauopathy.
Cheryl E G Leyns, Jason D Ulrich, Mary B Finn, Floy R Stewart, Lauren J Koscal, Javier Remolina Serrano, Grace O Robinson, Elise Anderson, Marco Colonna, David M Holtzman. Proc Natl Acad Sci U S A 2017
Times Cited: 217




List of shared articles



Times cited

Chronic TREM2 activation exacerbates Aβ-associated tau seeding and spreading.
Nimansha Jain, Caroline A Lewis, Jason D Ulrich, David M Holtzman. J Exp Med 2023
1

TREM2-independent microgliosis promotes tau-mediated neurodegeneration in the presence of ApoE4.
Maud Gratuze, Johannes C M Schlachetzki, Ricardo D'Oliveira Albanus, Nimansha Jain, Brenna Novotny, Logan Brase, Lea Rodriguez, Clayton Mansel, Michal Kipnis, Sydney O'Brien,[...]. Neuron 2023
0

Microglia-specific ApoE knock-out does not alter Alzheimer's disease plaque pathogenesis or gene expression.
Caden M Henningfield, Miguel A Arreola, Neelakshi Soni, Elizabeth E Spangenberg, Kim N Green. Glia 2022
9

Transgenic Mouse Models of Alzheimer's Disease: An Integrative Analysis.
Raquel Sanchez-Varo, Marina Mejias-Ortega, Juan Jose Fernandez-Valenzuela, Cristina Nuñez-Diaz, Laura Caceres-Palomo, Laura Vegas-Gomez, Elisabeth Sanchez-Mejias, Laura Trujillo-Estrada, Juan Antonio Garcia-Leon, Ines Moreno-Gonzalez,[...]. Int J Mol Sci 2022
6

Microglia: Friend and foe in tauopathy.
Kristian F Odfalk, Kevin F Bieniek, Sarah C Hopp. Prog Neurobiol 2022
2

LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions.
Peng Zhao, Yuanzhong Xu, Lu-Lin Jiang, Xuejun Fan, Zhiqiang Ku, Leike Li, Xiaoye Liu, Mi Deng, Hisashi Arase, Jay-Jiguang Zhu,[...]. Mol Neurodegener 2022
2

Neurodegenerative phagocytes mediate synaptic stripping in Neuro-HIV.
Giovanni Di Liberto, Kristof Egervari, Mario Kreutzfeldt, Christian M Schürch, Ekkehard Hewer, Ingrid Wagner, Renaud Du Pasquier, Doron Merkler. Brain 2022
1

Biological correlates of elevated soluble TREM2 in cerebrospinal fluid.
Rebecca L Winfree, Logan Dumitrescu, Kaj Blennow, Henrik Zetterberg, Katherine A Gifford, Kimberly R Pechman, Angela L Jefferson, Timothy J Hohman. Neurobiol Aging 2022
1

Elevating microglia TREM2 reduces amyloid seeding and suppresses disease-associated microglia.
Na Zhao, Wenhui Qiao, Fuyao Li, Yingxue Ren, Jiaying Zheng, Yuka A Martens, Xusheng Wang, Ling Li, Chia-Chen Liu, Kai Chen,[...]. J Exp Med 2022
0

Regulation of α-synuclein homeostasis and inflammasome activation by microglial autophagy.
Insup Choi, George R Heaton, You-Kyung Lee, Zhenyu Yue. Sci Adv 2022
2

Emerging roles of innate and adaptive immunity in Alzheimer's disease.
Xiaoying Chen, David M Holtzman. Immunity 2022
0

Inflammation context in Alzheimer's disease, a relationship intricate to define.
Catalina Novoa, Paulina Salazar, Pedro Cisternas, Camila Gherardelli, Roberto Vera-Salazar, Juan M Zolezzi, Nibaldo C Inestrosa. Biol Res 2022
0

TREM2 dependent and independent functions of microglia in Alzheimer's disease.
Jinchao Hou, Yun Chen, Gary Grajales-Reyes, Marco Colonna. Mol Neurodegener 2022
0

TREM2, microglia, and Alzheimer's disease.
Qi Qin, Zhaoqian Teng, Changmei Liu, Qian Li, Yunsi Yin, Yi Tang. Mech Ageing Dev 2021
32

Triggering receptor expressed on myeloid Cells-2 (TREM2) inhibits steroidogenesis in adrenocortical cell by macrophage-derived exosomes in lipopolysaccharide-induced septic shock.
Hui Ye, Qian Zhai, Ping Fang, Shiyue Yang, Yaqi Sun, Shuijing Wu, Ruoqiong Huang, Qixing Chen, Xiangming Fang. Mol Cell Endocrinol 2021
3

The role of innate immune genes in Alzheimer's disease.
Ana Griciuc, Rudolph E Tanzi. Curr Opin Neurol 2021
44

Trem2 restrains the enhancement of tau accumulation and neurodegeneration by β-amyloid pathology.
Seung-Hye Lee, William J Meilandt, Luke Xie, Vineela D Gandham, Hai Ngu, Kai H Barck, Mitchell G Rezzonico, Jose Imperio, Guita Lalehzadeh, Melanie A Huntley,[...]. Neuron 2021
67

Role of triggering receptor expressed on myeloid cells 2 (TREM2) in neurodegenerative dementias.
Sadat Shafi, Archu Singh, Abdallah Mohammad Ibrahim, Noora Alhajri, Tareq Abu Izneid, Faheem Hyder Pottoo. Eur J Neurosci 2021
5


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