A citation-based method for searching scientific literature

Annette Haacke, Sarah A Broadley, Raina Boteva, Nikolay Tzvetkov, F Ulrich Hartl, Peter Breuer. Hum Mol Genet 2006
Times Cited: 93



H L Paulson, M K Perez, Y Trottier, J Q Trojanowski, S H Subramony, S S Das, P Vig, J L Mandel, K H Fischbeck, R N Pittman. Neuron 1997
Times Cited: 659




List of shared articles



Times cited

Polyglutamine diseases: where does toxicity come from? what is toxicity? where are we going?
Toshiaki Takahashi, Shinichi Katada, Osamu Onodera. J Mol Cell Biol 2010
104


Unravelling Endogenous MicroRNA System Dysfunction as a New Pathophysiological Mechanism in Machado-Joseph Disease.
Vitor Carmona, Janete Cunha-Santos, Isabel Onofre, Ana Teresa Simões, Udaya Vijayakumar, Beverly L Davidson, Luís Pereira de Almeida. Mol Ther 2017
25

Valosin-containing protein (VCP/p97) is an activator of wild-type ataxin-3.
Mário N Laço, Luisa Cortes, Sue M Travis, Henry L Paulson, A Cristina Rego. PLoS One 2012
16

Calpain inhibition is sufficient to suppress aggregation of polyglutamine-expanded ataxin-3.
Annette Haacke, F Ulrich Hartl, Peter Breuer. J Biol Chem 2007
70

Drosophila as an In Vivo Model for Human Neurodegenerative Disease.
Leeanne McGurk, Amit Berson, Nancy M Bonini. Genetics 2015
131

N-terminal ataxin-3 causes neurological symptoms with inclusions, endoplasmic reticulum stress and ribosomal dislocation.
Jeannette Hübener, Franz Vauti, Claudia Funke, Hartwig Wolburg, Yihong Ye, Thorsten Schmidt, Karen Wolburg-Buchholz, Ina Schmitt, Adriane Gardyan, Stefan Driessen,[...]. Brain 2011
39

ULK overexpression mitigates motor deficits and neuropathology in mouse models of Machado-Joseph disease.
Ana Vasconcelos-Ferreira, Inês Morgado Martins, Diana Lobo, Dina Pereira, Miguel M Lopes, Rosário Faro, Sara M Lopes, Dineke Verbeek, Thorsten Schmidt, Clévio Nóbrega,[...]. Mol Ther 2021
1

PolyQ-expanded ataxin-3 interacts with full-length ataxin-3 in a polyQ length-dependent manner.
Na-Li Jia, Er-Kang Fei, Zheng Ying, Hong-Feng Wang, Guang-Hui Wang. Neurosci Bull 2008
6

Identification and functional dissection of localization signals within ataxin-3.
Paul Michel Aloyse Antony, Simone Mäntele, Phillip Mollenkopf, Jana Boy, Ralph H Kehlenbach, Olaf Riess, Thorsten Schmidt. Neurobiol Dis 2009
33

Calpain inhibition reduces ataxin-3 cleavage alleviating neuropathology and motor impairments in mouse models of Machado-Joseph disease.
Ana Teresa Simões, Nélio Gonçalves, Rui Jorge Nobre, Carlos Bandeira Duarte, Luís Pereira de Almeida. Hum Mol Genet 2014
36

Calpastatin-mediated inhibition of calpains in the mouse brain prevents mutant ataxin 3 proteolysis, nuclear localization and aggregation, relieving Machado-Joseph disease.
Ana T Simões, Nélio Gonçalves, Arnulf Koeppen, Nicole Déglon, Sebastian Kügler, Carlos Bandeira Duarte, Luís Pereira de Almeida. Brain 2012
80


From pathways to targets: understanding the mechanisms behind polyglutamine disease.
Jonasz Jeremiasz Weber, Anna Sergeevna Sowa, Tina Binder, Jeannette Hübener. Biomed Res Int 2014
34

A combinatorial approach to identify calpain cleavage sites in the Machado-Joseph disease protein ataxin-3.
Jonasz J Weber, Matthias Golla, Giambattista Guaitoli, Pimthanya Wanichawan, Stefanie N Hayer, Stefan Hauser, Ann-Christin Krahl, Maike Nagel, Sebastian Samer, Eleonora Aronica,[...]. Brain 2017
22

Toward understanding Machado-Joseph disease.
Maria do Carmo Costa, Henry L Paulson. Prog Neurobiol 2012
157

Antisense oligonucleotide therapy rescues aggresome formation in a novel spinocerebellar ataxia type 3 human embryonic stem cell line.
Lauren R Moore, Laura Keller, David D Bushart, Rodrigo G Delatorre, Duojia Li, Hayley S McLoughlin, Maria do Carmo Costa, Vikram G Shakkottai, Gary D Smith, Henry L Paulson. Stem Cell Res 2019
11

Study of subcellular localization and proteolysis of ataxin-3.
Chiara Pozzi, Marco Valtorta, Gabriella Tedeschi, Elena Galbusera, Valentina Pastori, Alessandra Bigi, Simona Nonnis, Eleonora Grassi, Paola Fusi. Neurobiol Dis 2008
44

Chaperones in Polyglutamine Aggregation: Beyond the Q-Stretch.
E F E Kuiper, Eduardo P de Mattos, Laura B Jardim, Harm H Kampinga, Steven Bergink. Front Neurosci 2017
26


RNA-binding protein misregulation in microsatellite expansion disorders.
Marianne Goodwin, Maurice S Swanson. Adv Exp Med Biol 2014
17

Polyglutamine diseases: the special case of ataxin-3 and Machado-Joseph disease.
Carlos A Matos, Sandra de Macedo-Ribeiro, Ana Luísa Carvalho. Prog Neurobiol 2011
89

Ataxin-3 protein and RNA toxicity in spinocerebellar ataxia type 3: current insights and emerging therapeutic strategies.
Melvin M Evers, Lodewijk J A Toonen, Willeke M C van Roon-Mom. Mol Neurobiol 2014
48

Molecular Mechanisms and Cellular Pathways Implicated in Machado-Joseph Disease Pathogenesis.
Clévio Nóbrega, Ana Teresa Simões, Joana Duarte-Neves, Sónia Duarte, Ana Vasconcelos-Ferreira, Janete Cunha-Santos, Dina Pereira, Magda Santana, Cláudia Cavadas, Luís Pereira de Almeida. Adv Exp Med Biol 2018
9

Identification of the calpain-generated toxic fragment of ataxin-3 protein provides new avenues for therapy of Machado-Joseph disease| Spinocerebellar ataxia type 3.
Ana Teresa Simões, Vítor Carmona, Joana Duarte-Neves, Janete Cunha-Santos, Luís Pereira de Almeida. Neuropathol Appl Neurobiol 2021
0

Flow cytometry allows rapid detection of protein aggregates in cellular and zebrafish models of spinocerebellar ataxia 3.
Katherine J Robinson, Madelaine C Tym, Alison Hogan, Maxinne Watchon, Kristy C Yuan, Stuart K Plenderleith, Emily K Don, Angela S Laird. Dis Model Mech 2021
1

Machado-Joseph disease/spinocerebellar ataxia type 3: lessons from disease pathogenesis and clues into therapy.
Carlos A Matos, Luís Pereira de Almeida, Clévio Nóbrega. J Neurochem 2019
39

From Pathogenesis to Novel Therapeutics for Spinocerebellar Ataxia Type 3: Evading Potholes on the Way to Translation.
Jorge Diogo Da Silva, Andreia Teixeira-Castro, Patrícia Maciel. Neurotherapeutics 2019
16

SCA3: neurological features, pathogenesis and animal models.
Olaf Riess, Udo Rüb, Annalisa Pastore, Peter Bauer, Ludger Schöls. Cerebellum 2008
149

A mutant ataxin-3 fragment results from processing at a site N-terminal to amino acid 190 in brain of Machado-Joseph disease-like transgenic mice.
Veronica F Colomer Gould, Daniel Goti, Donna Pearce, Guillermo A Gonzalez, Hong Gao, Mario Bermudez de Leon, Nancy A Jenkins, Neal G Copeland, Christopher A Ross, Dale R Brown. Neurobiol Dis 2007
39


The Truncated C-terminal Fragment of Mutant ATXN3 Disrupts Mitochondria Dynamics in Spinocerebellar Ataxia Type 3 Models.
Jung-Yu Hsu, Yu-Ling Jhang, Pei-Hsun Cheng, Yu-Fan Chang, Su-Han Mao, Han-In Yang, Chia-Wei Lin, Chuan-Mu Chen, Shang-Hsun Yang. Front Mol Neurosci 2017
19

Altered expression of carbonic anhydrase-related protein XI in neuronal cells expressing mutant ataxin-3.
Mingli Hsieh, Wei-Hsiu Chang, Chi-Fu Hsu, Isao Nishimori, Cheng-Liang Kuo, Tomoko Minakuchi. Cerebellum 2013
8

Polyglutamine-expanded androgen receptor truncation fragments activate a Bax-dependent apoptotic cascade mediated by DP5/Hrk.
Jessica E Young, Gwenn A Garden, Refugio A Martinez, Fumiaki Tanaka, C Miguel Sandoval, Annette C Smith, Bryce L Sopher, Amy Lin, Kenneth H Fischbeck, Lisa M Ellerby,[...]. J Neurosci 2009
49

Proteolytic Cleavage of Polyglutamine Disease-Causing Proteins: Revisiting the Toxic Fragment Hypothesis.
Carlos A Matos, Luis Pereira de Almeida, Clevio Nobrega. Curr Pharm Des 2017
16

Physiological and pathophysiological characteristics of ataxin-3 isoforms.
Daniel Weishäupl, Juliane Schneider, Barbara Peixoto Pinheiro, Corinna Ruess, Sandra Maria Dold, Felix von Zweydorf, Christian Johannes Gloeckner, Jana Schmidt, Olaf Riess, Thorsten Schmidt. J Biol Chem 2019
16