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List of shared articles
Times cited
Exome sequencing of individuals with Huntington's disease implicates FAN1 nuclease activity in slowing CAG expansion and disease onset.
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Branduff McAllister, Jasmine Donaldson, Caroline S Binda, Sophie Powell, Uroosa Chughtai, Gareth Edwards, Joseph Stone, Sergey Lobanov, Linda Elliston, Laura-Nadine Schuhmacher,[...]. Nat Neurosci 2022
Drugging DNA Damage Repair Pathways for Trinucleotide Repeat Expansion Diseases.
Caroline L Benn, Karl R Gibson, David S Reynolds. J Huntingtons Dis 2021
Caroline L Benn, Karl R Gibson, David S Reynolds. J Huntingtons Dis 2021
Modifiers of Somatic Repeat Instability in Mouse Models of Friedreich Ataxia and the Fragile X-Related Disorders: Implications for the Mechanism of Somatic Expansion in Huntington's Disease.
Xiaonan Zhao, Daman Kumari, Carson J Miller, Geum-Yi Kim, Bruce Hayward, Antonia G Vitalo, Ricardo Mouro Pinto, Karen Usdin. J Huntingtons Dis 2021
Xiaonan Zhao, Daman Kumari, Carson J Miller, Geum-Yi Kim, Bruce Hayward, Antonia G Vitalo, Ricardo Mouro Pinto, Karen Usdin. J Huntingtons Dis 2021
Modifiers of CAG/CTG Repeat Instability: Insights from Mammalian Models.
Vanessa C Wheeler, Vincent Dion. J Huntingtons Dis 2021
Vanessa C Wheeler, Vincent Dion. J Huntingtons Dis 2021
Somatic CAG expansion in Huntington's disease is dependent on the MLH3 endonuclease domain, which can be excluded via splice redirection.
Jennie C L Roy, Antonia Vitalo, Marissa A Andrew, Eduarda Mota-Silva, Marina Kovalenko, Zoe Burch, Anh M Nhu, Paula E Cohen, Ed Grabczyk, Vanessa C Wheeler,[...]. Nucleic Acids Res 2021
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Molecular mechanisms underlying nucleotide repeat expansion disorders.
Indranil Malik, Chase P Kelley, Eric T Wang, Peter K Todd. Nat Rev Mol Cell Biol 2021
Indranil Malik, Chase P Kelley, Eric T Wang, Peter K Todd. Nat Rev Mol Cell Biol 2021
On the wrong DNA track: Molecular mechanisms of repeat-mediated genome instability.
Alexandra N Khristich, Sergei M Mirkin. J Biol Chem 2020
Alexandra N Khristich, Sergei M Mirkin. J Biol Chem 2020
A slipped-CAG DNA-binding small molecule induces trinucleotide-repeat contractions in vivo.
Masayuki Nakamori, Gagan B Panigrahi, Stella Lanni, Terence Gall-Duncan, Hideki Hayakawa, Hana Tanaka, Jennifer Luo, Takahiro Otabe, Jinxing Li, Akihiro Sakata,[...]. Nat Genet 2020
Masayuki Nakamori, Gagan B Panigrahi, Stella Lanni, Terence Gall-Duncan, Hideki Hayakawa, Hana Tanaka, Jennifer Luo, Takahiro Otabe, Jinxing Li, Akihiro Sakata,[...]. Nat Genet 2020
Patterns of CAG repeat instability in the central nervous system and periphery in Huntington's disease and in spinocerebellar ataxia type 1.
Ricardo Mouro Pinto, Larissa Arning, James V Giordano, Pedram Razghandi, Marissa A Andrew, Tammy Gillis, Kevin Correia, Jayalakshmi S Mysore, Debora-M Grote Urtubey, Constanze R Parwez,[...]. Hum Mol Genet 2020
Ricardo Mouro Pinto, Larissa Arning, James V Giordano, Pedram Razghandi, Marissa A Andrew, Tammy Gillis, Kevin Correia, Jayalakshmi S Mysore, Debora-M Grote Urtubey, Constanze R Parwez,[...]. Hum Mol Genet 2020
Histone deacetylase knockouts modify transcription, CAG instability and nuclear pathology in Huntington disease mice.
Marina Kovalenko, Serkan Erdin, Marissa A Andrew, Jason St Claire, Melissa Shaughnessey, Leroy Hubert, João Luís Neto, Alexei Stortchevoi, Daniel M Fass, Ricardo Mouro Pinto,[...]. Elife 2020
Marina Kovalenko, Serkan Erdin, Marissa A Andrew, Jason St Claire, Melissa Shaughnessey, Leroy Hubert, João Luís Neto, Alexei Stortchevoi, Daniel M Fass, Ricardo Mouro Pinto,[...]. Elife 2020
New developments in Huntington's disease and other triplet repeat diseases: DNA repair turns to the dark side.
Robert S Lahue. Neuronal Signal 2020
Robert S Lahue. Neuronal Signal 2020
The central role of DNA damage and repair in CAG repeat diseases.
Thomas H Massey, Lesley Jones. Dis Model Mech 2018
Thomas H Massey, Lesley Jones. Dis Model Mech 2018
GAA•TTC repeat expansion in human cells is mediated by mismatch repair complex MutLγ and depends upon the endonuclease domain in MLH3 isoform one.
Anasheh Halabi, Kayla T B Fuselier, Ed Grabczyk. Nucleic Acids Res 2018
Anasheh Halabi, Kayla T B Fuselier, Ed Grabczyk. Nucleic Acids Res 2018
Timing of Expansion of Fragile X Premutation Alleles During Intergenerational Transmission in a Mouse Model of the Fragile X-Related Disorders.
Xiao-Nan Zhao, Karen Usdin. Front Genet 2018
Xiao-Nan Zhao, Karen Usdin. Front Genet 2018
Close encounters: Moving along bumps, breaks, and bubbles on expanded trinucleotide tracts.
Aris A Polyzos, Cynthia T McMurray. DNA Repair (Amst) 2017
Aris A Polyzos, Cynthia T McMurray. DNA Repair (Amst) 2017
A selective inhibitor of histone deacetylase 3 prevents cognitive deficits and suppresses striatal CAG repeat expansions in Huntington's disease mice.
Nuria Suelves, Lucy Kirkham-McCarthy, Robert S Lahue, Silvia Ginés. Sci Rep 2017
Nuria Suelves, Lucy Kirkham-McCarthy, Robert S Lahue, Silvia Ginés. Sci Rep 2017
Repeat instability during DNA repair: Insights from model systems.
Karen Usdin, Nealia C M House, Catherine H Freudenreich. Crit Rev Biochem Mol Biol 2015
Karen Usdin, Nealia C M House, Catherine H Freudenreich. Crit Rev Biochem Mol Biol 2015
The Repeat Expansion Diseases: The dark side of DNA repair.
Xiao-Nan Zhao, Karen Usdin. DNA Repair (Amst) 2015
Xiao-Nan Zhao, Karen Usdin. DNA Repair (Amst) 2015
Huntington disease.
Gillian P Bates, Ray Dorsey, James F Gusella, Michael R Hayden, Chris Kay, Blair R Leavitt, Martha Nance, Christopher A Ross, Rachael I Scahill, Ronald Wetzel,[...]. Nat Rev Dis Primers 2015
Gillian P Bates, Ray Dorsey, James F Gusella, Michael R Hayden, Chris Kay, Blair R Leavitt, Martha Nance, Christopher A Ross, Rachael I Scahill, Ronald Wetzel,[...]. Nat Rev Dis Primers 2015
Expression levels of DNA replication and repair genes predict regional somatic repeat instability in the brain but are not altered by polyglutamine disease protein expression or age.
Amanda G Mason, Stephanie Tomé, Jodie P Simard, Randell T Libby, Theodor K Bammler, Richard P Beyer, A Jennifer Morton, Christopher E Pearson, Albert R La Spada. Hum Mol Genet 2014
Amanda G Mason, Stephanie Tomé, Jodie P Simard, Randell T Libby, Theodor K Bammler, Richard P Beyer, A Jennifer Morton, Christopher E Pearson, Albert R La Spada. Hum Mol Genet 2014
The dual nature of mismatch repair as antimutator and mutator: for better or for worse.
Sara Thornby Bak, Despoina Sakellariou, Javier Pena-Diaz. Front Genet 2014
Sara Thornby Bak, Despoina Sakellariou, Javier Pena-Diaz. Front Genet 2014
Mismatch repair genes Mlh1 and Mlh3 modify CAG instability in Huntington's disease mice: genome-wide and candidate approaches.
Ricardo Mouro Pinto, Ella Dragileva, Andrew Kirby, Alejandro Lloret, Edith Lopez, Jason St Claire, Gagan B Panigrahi, Caixia Hou, Kim Holloway, Tammy Gillis,[...]. PLoS Genet 2013
Ricardo Mouro Pinto, Ella Dragileva, Andrew Kirby, Alejandro Lloret, Edith Lopez, Jason St Claire, Gagan B Panigrahi, Caixia Hou, Kim Holloway, Tammy Gillis,[...]. PLoS Genet 2013