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Pathogenic Mechanisms Underlying Idiopathic Pulmonary Fibrosis.
Benjamin J Moss, Stefan W Ryter, Ivan O Rosas. Annu Rev Pathol 2022
Benjamin J Moss, Stefan W Ryter, Ivan O Rosas. Annu Rev Pathol 2022
COVID-19 lung disease shares driver AT2 cytopathic features with Idiopathic pulmonary fibrosis.
Saptarshi Sinha, Vanessa Castillo, Celia R Espinoza, Courtney Tindle, Ayden G Fonseca, Jennifer M Dan, Gajanan D Katkar, Soumita Das, Debashis Sahoo, Pradipta Ghosh. bioRxiv 2022
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A census of the lung: CellCards from LungMAP.
Xin Sun, Anne-Karina Perl, Rongbo Li, Sheila M Bell, Eniko Sajti, Vladimir V Kalinichenko, Tanya V Kalin, Ravi S Misra, Hitesh Deshmukh, Geremy Clair,[...]. Dev Cell 2022
Xin Sun, Anne-Karina Perl, Rongbo Li, Sheila M Bell, Eniko Sajti, Vladimir V Kalinichenko, Tanya V Kalin, Ravi S Misra, Hitesh Deshmukh, Geremy Clair,[...]. Dev Cell 2022
Human alveolar type 2 epithelium transdifferentiates into metaplastic KRT5+ basal cells.
Jaymin J Kathiriya, Chaoqun Wang, Minqi Zhou, Alexis Brumwell, Monica Cassandras, Claude Jourdan Le Saux, Max Cohen, Kostantinos-Dionysios Alysandratos, Bruce Wang, Paul Wolters,[...]. Nat Cell Biol 2022
Jaymin J Kathiriya, Chaoqun Wang, Minqi Zhou, Alexis Brumwell, Monica Cassandras, Claude Jourdan Le Saux, Max Cohen, Kostantinos-Dionysios Alysandratos, Bruce Wang, Paul Wolters,[...]. Nat Cell Biol 2022
The lipid transporter Mfsd2a maintains pulmonary surfactant homeostasis.
Bernice H Wong, Ding Mei, Geok Lin Chua, Dwight L Galam, Markus R Wenk, Federico Torta, David L Silver. J Biol Chem 2022
Bernice H Wong, Ding Mei, Geok Lin Chua, Dwight L Galam, Markus R Wenk, Federico Torta, David L Silver. J Biol Chem 2022
Effect of lung pericyte-like cell ablation on the bleomycin model of injury and repair.
Chi F Hung, Carole L Wilson, Yu-Hua Chow, Wayne C Liles, Sina A Gharib, William A Altemeier, Lynn M Schnapp. Am J Physiol Lung Cell Mol Physiol 2022
Chi F Hung, Carole L Wilson, Yu-Hua Chow, Wayne C Liles, Sina A Gharib, William A Altemeier, Lynn M Schnapp. Am J Physiol Lung Cell Mol Physiol 2022
Extracellular Lipids in the Lung and Their Role in Pulmonary Fibrosis.
Olivier Burgy, Sabrina Loriod, Guillaume Beltramo, Philippe Bonniaud. Cells 2022
Olivier Burgy, Sabrina Loriod, Guillaume Beltramo, Philippe Bonniaud. Cells 2022
Identification, discrimination and heterogeneity of fibroblasts.
Urban Lendahl, Lars Muhl, Christer Betsholtz. Nat Commun 2022
Urban Lendahl, Lars Muhl, Christer Betsholtz. Nat Commun 2022
Inhibition of PDIA3 in club cells attenuates osteopontin production and lung fibrosis.
Amit Kumar, Evan Elko, Sierra R Bruno, Zoe F Mark, Nicolas Chamberlain, Bethany Korwin Mihavics, Ravishankar Chandrasekaran, Joseph Walzer, Mona Ruban, Clarissa Gold,[...]. Thorax 2022
Amit Kumar, Evan Elko, Sierra R Bruno, Zoe F Mark, Nicolas Chamberlain, Bethany Korwin Mihavics, Ravishankar Chandrasekaran, Joseph Walzer, Mona Ruban, Clarissa Gold,[...]. Thorax 2022
Characterization of the COPD alveolar niche using single-cell RNA sequencing.
Maor Sauler, John E McDonough, Taylor S Adams, Neeharika Kothapalli, Thomas Barnthaler, Rhiannon B Werder, Jonas C Schupp, Jessica Nouws, Matthew J Robertson, Cristian Coarfa,[...]. Nat Commun 2022
Maor Sauler, John E McDonough, Taylor S Adams, Neeharika Kothapalli, Thomas Barnthaler, Rhiannon B Werder, Jonas C Schupp, Jessica Nouws, Matthew J Robertson, Cristian Coarfa,[...]. Nat Commun 2022
Bronchial epithelium epithelial-mesenchymal plasticity forms aberrant basaloid-like cells in vitro.
Dinesh Babu Uthaya Kumar, Efthymios Motakis, Marina Yurieva, Vivek Kohar, Jan Martinek, Te-Chia Wu, Johad Khoury, Jessica Grassmann, Mingyang Lu, Karolina Palucka,[...]. Am J Physiol Lung Cell Mol Physiol 2022
Dinesh Babu Uthaya Kumar, Efthymios Motakis, Marina Yurieva, Vivek Kohar, Jan Martinek, Te-Chia Wu, Johad Khoury, Jessica Grassmann, Mingyang Lu, Karolina Palucka,[...]. Am J Physiol Lung Cell Mol Physiol 2022
Recent developments in the pathobiology of lung myofibroblasts.
Dingyuan Jiang, Tapan Dey, Gang Liu. Expert Rev Respir Med 2021
Dingyuan Jiang, Tapan Dey, Gang Liu. Expert Rev Respir Med 2021
Pretreatment of aged mice with retinoic acid supports alveolar regeneration via upregulation of reciprocal PDGFA signalling.
Jason J Gokey, John Snowball, Jenna Green, Marion Waltamath, Jillian J Spinney, Katharine E Black, Lida P Hariri, Yan Xu, Anne Karina Perl. Thorax 2021
Jason J Gokey, John Snowball, Jenna Green, Marion Waltamath, Jillian J Spinney, Katharine E Black, Lida P Hariri, Yan Xu, Anne Karina Perl. Thorax 2021
Stromal-immune cell crosstalk fundamentally alters the lung microenvironment following tissue insult.
Julie C Worrell, Megan K L MacLeod. Immunology 2021
Julie C Worrell, Megan K L MacLeod. Immunology 2021
Targeting Alveolar Repair in Idiopathic Pulmonary Fibrosis.
Victoria A Ptasinski, John Stegmayr, Maria G Belvisi, Darcy E Wagner, Lynne A Murray. Am J Respir Cell Mol Biol 2021
Victoria A Ptasinski, John Stegmayr, Maria G Belvisi, Darcy E Wagner, Lynne A Murray. Am J Respir Cell Mol Biol 2021
Idiopathic pulmonary fibrosis and systemic sclerosis: pathogenic mechanisms and therapeutic interventions.
Hamid Mattoo, Shiv Pillai. Cell Mol Life Sci 2021
Hamid Mattoo, Shiv Pillai. Cell Mol Life Sci 2021
Dissecting the Role of Mesenchymal Stem Cells in Idiopathic Pulmonary Fibrosis: Cause or Solution.
Anna Valeria Samarelli, Roberto Tonelli, Irene Heijink, Aina Martin Medina, Alessandro Marchioni, Giulia Bruzzi, Ivana Castaniere, Dario Andrisani, Filippo Gozzi, Linda Manicardi,[...]. Front Pharmacol 2021
Anna Valeria Samarelli, Roberto Tonelli, Irene Heijink, Aina Martin Medina, Alessandro Marchioni, Giulia Bruzzi, Ivana Castaniere, Dario Andrisani, Filippo Gozzi, Linda Manicardi,[...]. Front Pharmacol 2021
Dysregulated overexpression of Sox9 induces fibroblast activation in pulmonary fibrosis.
Prathibha R Gajjala, Rajesh K Kasam, Divyalakshmi Soundararajan, Debora Sinner, Steven K Huang, Anil G Jegga, Satish K Madala. JCI Insight 2021
Prathibha R Gajjala, Rajesh K Kasam, Divyalakshmi Soundararajan, Debora Sinner, Steven K Huang, Anil G Jegga, Satish K Madala. JCI Insight 2021
Modeling of lung phenotype of Hermansky-Pudlak syndrome type I using patient-specific iPSCs.
Takahiro Suezawa, Shuhei Kanagaki, Yohei Korogi, Kazuhisa Nakao, Toyohiro Hirai, Koji Murakami, Masatoshi Hagiwara, Shimpei Gotoh. Respir Res 2021
Takahiro Suezawa, Shuhei Kanagaki, Yohei Korogi, Kazuhisa Nakao, Toyohiro Hirai, Koji Murakami, Masatoshi Hagiwara, Shimpei Gotoh. Respir Res 2021
Metabolic requirements of pulmonary fibrosis: role of fibroblast metabolism.
Robert B Hamanaka, Gökhan M Mutlu. FEBS J 2021
Robert B Hamanaka, Gökhan M Mutlu. FEBS J 2021
Persistent, Progressive Pulmonary Fibrosis and Epithelial Remodeling in Mice.
Elizabeth F Redente, Bart P Black, Donald S Backos, Ali N Bahadur, Stephen M Humphries, David A Lynch, Rubin M Tuder, Rachel L Zemans, David W H Riches. Am J Respir Cell Mol Biol 2021
Elizabeth F Redente, Bart P Black, Donald S Backos, Ali N Bahadur, Stephen M Humphries, David A Lynch, Rubin M Tuder, Rachel L Zemans, David W H Riches. Am J Respir Cell Mol Biol 2021
Resetting proteostasis with ISRIB promotes epithelial differentiation to attenuate pulmonary fibrosis.
Satoshi Watanabe, Nikolay S Markov, Ziyan Lu, Raul Piseaux Aillon, Saul Soberanes, Constance E Runyan, Ziyou Ren, Rogan A Grant, Mariana Maciel, Hiam Abdala-Valencia,[...]. Proc Natl Acad Sci U S A 2021
Satoshi Watanabe, Nikolay S Markov, Ziyan Lu, Raul Piseaux Aillon, Saul Soberanes, Constance E Runyan, Ziyou Ren, Rogan A Grant, Mariana Maciel, Hiam Abdala-Valencia,[...]. Proc Natl Acad Sci U S A 2021
Fibroblasts positive for meflin have anti-fibrotic properties in pulmonary fibrosis.
Yoshio Nakahara, Naozumi Hashimoto, Koji Sakamoto, Atsushi Enomoto, Taylor S Adams, Toyoharu Yokoi, Norihito Omote, Sergio Poli, Akira Ando, Keiko Wakahara,[...]. Eur Respir J 2021
Yoshio Nakahara, Naozumi Hashimoto, Koji Sakamoto, Atsushi Enomoto, Taylor S Adams, Toyoharu Yokoi, Norihito Omote, Sergio Poli, Akira Ando, Keiko Wakahara,[...]. Eur Respir J 2021
Categorization of lung mesenchymal cells in development and fibrosis.
Xue Liu, Simon C Rowan, Jiurong Liang, Changfu Yao, Guanling Huang, Nan Deng, Ting Xie, Di Wu, Yizhou Wang, Ankita Burman,[...]. iScience 2021
Xue Liu, Simon C Rowan, Jiurong Liang, Changfu Yao, Guanling Huang, Nan Deng, Ting Xie, Di Wu, Yizhou Wang, Ankita Burman,[...]. iScience 2021