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Advancing preclinical models of psychiatric disorders with human brain organoid cultures.
Thomas Anthony Dixon, Alysson R Muotri. Mol Psychiatry 2023
Thomas Anthony Dixon, Alysson R Muotri. Mol Psychiatry 2023
Microglia-containing human brain organoids for the study of brain development and pathology.
Wendiao Zhang, Jiamei Jiang, Zhenhong Xu, Hongye Yan, Beisha Tang, Chunyu Liu, Chao Chen, Qingtuan Meng. Mol Psychiatry 2023
Wendiao Zhang, Jiamei Jiang, Zhenhong Xu, Hongye Yan, Beisha Tang, Chunyu Liu, Chao Chen, Qingtuan Meng. Mol Psychiatry 2023
Gene-Edited Fluorescent and Mixed Cerebral Organoids.
Lisa Bachmann, Lucia Gallego Villarejo, Natalie Heinen, David Marks, Marcus Peters, Thorsten Müller. CRISPR J 2022
Lisa Bachmann, Lucia Gallego Villarejo, Natalie Heinen, David Marks, Marcus Peters, Thorsten Müller. CRISPR J 2022
Modeling PCDH19-CE: From 2D Stem Cell Model to 3D Brain Organoids.
Rossella Borghi, Valentina Magliocca, Marina Trivisano, Nicola Specchio, Marco Tartaglia, Enrico Bertini, Claudia Compagnucci. Int J Mol Sci 2022
Rossella Borghi, Valentina Magliocca, Marina Trivisano, Nicola Specchio, Marco Tartaglia, Enrico Bertini, Claudia Compagnucci. Int J Mol Sci 2022
Physiological Electric Field: A Potential Construction Regulator of Human Brain Organoids.
Xiyao Yu, Xiaoting Meng, Zhe Pei, Guoqiang Wang, Rongrong Liu, Mingran Qi, Jiaying Zhou, Fang Wang. Int J Mol Sci 2022
Xiyao Yu, Xiaoting Meng, Zhe Pei, Guoqiang Wang, Rongrong Liu, Mingran Qi, Jiaying Zhou, Fang Wang. Int J Mol Sci 2022
Human cerebral spheroids undergo 4-aminopyridine-induced, activity associated changes in cellular composition and microrna expression.
Thomas Parmentier, Fiona M K James, Elizabeth Hewitson, Craig Bailey, Nicholas Werry, Steven D Sheridan, Roy H Perlis, Melissa L Perreault, Luis Gaitero, Jasmin Lalonde,[...]. Sci Rep 2022
Thomas Parmentier, Fiona M K James, Elizabeth Hewitson, Craig Bailey, Nicholas Werry, Steven D Sheridan, Roy H Perlis, Melissa L Perreault, Luis Gaitero, Jasmin Lalonde,[...]. Sci Rep 2022
Human Brain-Based Models Provide a Powerful Tool for the Advancement of Parkinson's Disease Research and Therapeutic Development.
Sarah F McComish, Adina N MacMahon Copas, Maeve A Caldwell. Front Neurosci 2022
Sarah F McComish, Adina N MacMahon Copas, Maeve A Caldwell. Front Neurosci 2022
Orgo-Seq integrates single-cell and bulk transcriptomic data to identify cell type specific-driver genes associated with autism spectrum disorder.
Elaine T Lim, Yingleong Chan, Pepper Dawes, Xiaoge Guo, Serkan Erdin, Derek J C Tai, Songlei Liu, Julia M Reichert, Mannix J Burns, Ying Kai Chan,[...]. Nat Commun 2022
Elaine T Lim, Yingleong Chan, Pepper Dawes, Xiaoge Guo, Serkan Erdin, Derek J C Tai, Songlei Liu, Julia M Reichert, Mannix J Burns, Ying Kai Chan,[...]. Nat Commun 2022
3D printed human organoids: High throughput system for drug screening and testing in current COVID-19 pandemic.
Arpana Parihar, Vasundhara Pandita, Raju Khan. Biotechnol Bioeng 2022
Arpana Parihar, Vasundhara Pandita, Raju Khan. Biotechnol Bioeng 2022
Human mini brains and spinal cords in a dish: Modeling strategies, current challenges, and prospective advances.
Simeon Kofman, Neha Mohan, Xiaohuan Sun, Larisa Ibric, Emanuela Piermarini, Liang Qiang. J Tissue Eng 2022
Simeon Kofman, Neha Mohan, Xiaohuan Sun, Larisa Ibric, Emanuela Piermarini, Liang Qiang. J Tissue Eng 2022
Imaging three-dimensional brain organoid architecture from meso- to nanoscale across development.
Juan Eduardo Rodriguez-Gatica, Vira Iefremova, Liubov Sokhranyaeva, Si Wah Christina Au Yeung, Yannik Breitkreuz, Oliver Brüstle, Martin Karl Schwarz, Ulrich Kubitscheck. Development 2022
Juan Eduardo Rodriguez-Gatica, Vira Iefremova, Liubov Sokhranyaeva, Si Wah Christina Au Yeung, Yannik Breitkreuz, Oliver Brüstle, Martin Karl Schwarz, Ulrich Kubitscheck. Development 2022
Human tau mutations in cerebral organoids induce a progressive dyshomeostasis of cholesterol.
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Pax6 mutant cerebral organoids partially recapitulate phenotypes of Pax6 mutant mouse strains.
Nurfarhana Ferdaos, Sally Lowell, John O Mason. PLoS One 2022
Nurfarhana Ferdaos, Sally Lowell, John O Mason. PLoS One 2022
Synthetic scaffolds for 3D cell cultures and organoids: applications in regenerative medicine.
Amanda Marchini, Fabrizio Gelain. Crit Rev Biotechnol 2022
Amanda Marchini, Fabrizio Gelain. Crit Rev Biotechnol 2022
Modeling Developmental Brain Diseases Using Human Pluripotent Stem Cells-Derived Brain Organoids - Progress and Perspective.
Afrin Bhattacharya, Wendy W Y Choi, Julien Muffat, Yun Li. J Mol Biol 2022
Afrin Bhattacharya, Wendy W Y Choi, Julien Muffat, Yun Li. J Mol Biol 2022
Androgens increase excitatory neurogenic potential in human brain organoids.
Iva Kelava, Ilaria Chiaradia, Laura Pellegrini, Alex T Kalinka, Madeline A Lancaster. Nature 2022
Iva Kelava, Ilaria Chiaradia, Laura Pellegrini, Alex T Kalinka, Madeline A Lancaster. Nature 2022