A citation-based method for searching scientific literature

Clotilde Lagier-Tourenne, Michael Baughn, Frank Rigo, Shuying Sun, Patrick Liu, Hai-Ri Li, Jie Jiang, Andrew T Watt, Seung Chun, Melanie Katz, Jinsong Qiu, Ying Sun, Shuo-Chien Ling, Qiang Zhu, Magdalini Polymenidou, Kevin Drenner, Jonathan W Artates, Melissa McAlonis-Downes, Sebastian Markmiller, Kasey R Hutt, Donald P Pizzo, Janet Cady, Matthew B Harms, Robert H Baloh, Scott R Vandenberg, Gene W Yeo, Xiang-Dong Fu, C Frank Bennett, Don W Cleveland, John Ravits. Proc Natl Acad Sci U S A 2013
Times Cited: 366



Alan E Renton, Elisa Majounie, Adrian Waite, Javier Simón-Sánchez, Sara Rollinson, J Raphael Gibbs, Jennifer C Schymick, Hannu Laaksovirta, John C van Swieten, Liisa Myllykangas, Hannu Kalimo, Anders Paetau, Yevgeniya Abramzon, Anne M Remes, Alice Kaganovich, Sonja W Scholz, Jamie Duckworth, Jinhui Ding, Daniel W Harmer, Dena G Hernandez, Janel O Johnson, Kin Mok, Mina Ryten, Danyah Trabzuni, Rita J Guerreiro, Richard W Orrell, James Neal, Alex Murray, Justin Pearson, Iris E Jansen, David Sondervan, Harro Seelaar, Derek Blake, Kate Young, Nicola Halliwell, Janis Bennion Callister, Greg Toulson, Anna Richardson, Alex Gerhard, Julie Snowden, David Mann, David Neary, Michael A Nalls, Terhi Peuralinna, Lilja Jansson, Veli-Matti Isoviita, Anna-Lotta Kaivorinne, Maarit Hölttä-Vuori, Elina Ikonen, Raimo Sulkava, Michael Benatar, Joanne Wuu, Adriano Chiò, Gabriella Restagno, Giuseppe Borghero, Mario Sabatelli, David Heckerman, Ekaterina Rogaeva, Lorne Zinman, Jeffrey D Rothstein, Michael Sendtner, Carsten Drepper, Evan E Eichler, Can Alkan, Ziedulla Abdullaev, Svetlana D Pack, Amalia Dutra, Evgenia Pak, John Hardy, Andrew Singleton, Nigel M Williams, Peter Heutink, Stuart Pickering-Brown, Huw R Morris, Pentti J Tienari, Bryan J Traynor. Neuron 2011
Times Cited: 2606




List of shared articles



Times cited

Ablation of C9orf72 together with excitotoxicity induces ALS in rats.
Wei Dong, Yuanwu Ma, Feifei Guan, Xu Zhang, Wei Chen, Li Zhang, Lianfeng Zhang. FEBS J 2021
2

Long non-coding RNAs in motor neuron development and disease.
Vamshidhar R Vangoor, Andreia Gomes-Duarte, R Jeroen Pasterkamp. J Neurochem 2021
5

Antisense Drugs Make Sense for Neurological Diseases.
C Frank Bennett, Holly B Kordasiewicz, Don W Cleveland. Annu Rev Pharmacol Toxicol 2021
3


Glial Cell Dysfunction in C9orf72-Related Amyotrophic Lateral Sclerosis and Frontotemporal Dementia.
Mehdi Ghasemi, Kiandokht Keyhanian, Catherine Douthwright. Cells 2021
3

Combating deleterious phase transitions in neurodegenerative disease.
April L Darling, James Shorter. Biochim Biophys Acta Mol Cell Res 2021
7

Variant-selective stereopure oligonucleotides protect against pathologies associated with C9orf72-repeat expansion in preclinical models.
Yuanjing Liu, Jean-Cosme Dodart, Helene Tran, Shaunna Berkovitch, Maurine Braun, Michael Byrne, Ann F Durbin, Xiao Shelley Hu, Naoki Iwamoto, Hyun Gyung Jang,[...]. Nat Commun 2021
2

Emerging Perspectives on Dipeptide Repeat Proteins in C9ORF72 ALS/FTD.
Alexander Schmitz, João Pinheiro Marques, Irina Oertig, Niran Maharjan, Smita Saxena. Front Cell Neurosci 2021
0

Porphyrins ameliorate spinocerebellar ataxia type 36 GGCCTG repeat expansion-mediated cytotoxicity.
Kimitoshi Hirayanagi, Hiroaki Ozaki, Setsuki Tsukagoshi, Natsumi Furuta, Yoshio Ikeda. Neurosci Res 2021
0

BET bromodomain inhibitors PFI-1 and JQ1 are identified in an epigenetic compound screen to enhance C9ORF72 gene expression and shown to ameliorate C9ORF72-associated pathological and behavioral abnormalities in a C9ALS/FTD model.
Esteban Quezada, Claudio Cappelli, Iván Diaz, Nur Jury, Nicholas Wightman, Robert H Brown, Martín Montecino, Brigitte van Zundert. Clin Epigenetics 2021
0

Expression of C9orf72 hexanucleotide repeat expansion leads to formation of RNA foci and dipeptide repeat proteins but does not influence autophagy or proteasomal function in neuronal cells.
Stina Leskelä, Nadine Huber, Dorit Hoffmann, Hannah Rostalski, Anne M Remes, Mari Takalo, Mikko Hiltunen, Annakaisa Haapasalo. Biochim Biophys Acta Mol Cell Res 2021
0

The Molecular Function of PURA and Its Implications in Neurological Diseases.
Lena Molitor, Sabrina Bacher, Sandra Burczyk, Dierk Niessing. Front Genet 2021
0

Characterization of C9orf72 haplotypes to evaluate the effects of normal and pathological variations on its expression and splicing.
Israel Ben-Dor, Crystal Pacut, Yuval Nevo, Eva L Feldman, Benjamin E Reubinoff. PLoS Genet 2021
0

UPF1 reduces C9orf72 HRE-induced neurotoxicity in the absence of nonsense-mediated decay dysfunction.
Benjamin L Zaepfel, Zhe Zhang, Kirstin Maulding, Alyssa N Coyne, Weiwei Cheng, Lindsey R Hayes, Thomas E Lloyd, Shuying Sun, Jeffrey D Rothstein. Cell Rep 2021
2

Proteostatic imbalance and protein spreading in amyotrophic lateral sclerosis.
Maria Elena Cicardi, Lara Marrone, Mimoun Azzouz, Davide Trotti. EMBO J 2021
3

Gene therapy for ALS: A review.
Defne A Amado, Beverly L Davidson. Mol Ther 2021
1

A Helicase Unwinds Hexanucleotide Repeat RNA G-Quadruplexes and Facilitates Repeat-Associated Non-AUG Translation.
Honghe Liu, Yu-Ning Lu, Tapas Paul, Goran Periz, Michael T Banco, Adrian R Ferré-D'Amaré, Jeffrey D Rothstein, Lindsey R Hayes, Sua Myong, Jiou Wang. J Am Chem Soc 2021
2

Altered Phase Separation and Cellular Impact in C9orf72-Linked ALS/FTD.
Daniel A Solomon, Rebekah Smikle, Matthew J Reid, Sarah Mizielinska. Front Cell Neurosci 2021
0

C9ORF72: What It Is, What It Does, and Why It Matters.
Julie Smeyers, Elena-Gaia Banchi, Morwena Latouche. Front Cell Neurosci 2021
0

Disease Mechanisms and Therapeutic Approaches in C9orf72 ALS-FTD.
Keith Mayl, Christopher E Shaw, Youn-Bok Lee. Biomedicines 2021
0

Multiple pathways of toxicity induced by C9orf72 dipeptide repeat aggregates and G4C2 RNA in a cellular model.
Frédéric Frottin, Manuela Pérez-Berlanga, F Ulrich Hartl, Mark S Hipp. Elife 2021
0

Roles of non-canonical structures of nucleic acids in cancer and neurodegenerative diseases.
Hisae Tateishi-Karimata, Naoki Sugimoto. Nucleic Acids Res 2021
0

FTLD Patient-Derived Fibroblasts Show Defective Mitochondrial Function and Accumulation of p62.
Stina Leskelä, Dorit Hoffmann, Hannah Rostalski, Nadine Huber, Rebekka Wittrahm, Päivi Hartikainen, Ville Korhonen, Ville Leinonen, Mikko Hiltunen, Eino Solje,[...]. Mol Neurobiol 2021
0

RNA Is a Double-Edged Sword in ALS Pathogenesis.
Benjamin L Zaepfel, Jeffrey D Rothstein. Front Cell Neurosci 2021
0

Nuclear export and translation of circular repeat-containing intronic RNA in C9ORF72-ALS/FTD.
Shaopeng Wang, Malgorzata J Latallo, Zhe Zhang, Bo Huang, Dmitriy G Bobrovnikov, Daoyuan Dong, Nathan M Livingston, Wilson Tjoeng, Lindsey R Hayes, Jeffrey D Rothstein,[...]. Nat Commun 2021
1

Multifaceted role of SMCR8 as autophagy regulator.
Jennifer Jung, Christian Behrends. Small GTPases 2020
7

RNA toxicity in non-coding repeat expansion disorders.
Bart Swinnen, Wim Robberecht, Ludo Van Den Bosch. EMBO J 2020
65

Toxicity in ALS: TDP-43 modifiers and C9orf72.
Jessie L St Martin, Lina Wang, Zaven Kaprielian. Neurosci Lett 2020
2

Mutant C9orf72 human iPSC-derived astrocytes cause non-cell autonomous motor neuron pathophysiology.
Chen Zhao, Anna-Claire Devlin, Amit K Chouhan, Bhuvaneish T Selvaraj, Maria Stavrou, Karen Burr, Veronica Brivio, Xin He, Arpan R Mehta, David Story,[...]. Glia 2020
28

Reduced autophagy upon C9ORF72 loss synergizes with dipeptide repeat protein toxicity in G4C2 repeat expansion disorders.
Manon Boivin, Véronique Pfister, Angeline Gaucherot, Frank Ruffenach, Luc Negroni, Chantal Sellier, Nicolas Charlet-Berguerand. EMBO J 2020
31

Pharmacological prospects of G-quadruplexes for neurological diseases using porphyrins.
Sefan Asamitsu, Yasushi Yabuki, Susumu Ikenoshita, Takahito Wada, Norifumi Shioda. Biochem Biophys Res Commun 2020
2

Structural Diversity of Sense and Antisense RNA Hexanucleotide Repeats Associated with ALS and FTLD.
Tim Božič, Matja Zalar, Boris Rogelj, Janez Plavec, Primož Šket. Molecules 2020
4

Widespread loss of the silencing epigenetic mark H3K9me3 in astrocytes and neurons along with hippocampal-dependent cognitive impairment in C9orf72 BAC transgenic mice.
Nur Jury, Sebastian Abarzua, Ivan Diaz, Miguel V Guerra, Estibaliz Ampuero, Paula Cubillos, Pablo Martinez, Andrea Herrera-Soto, Cristian Arredondo, Fabiola Rojas,[...]. Clin Epigenetics 2020
8

The Hitchhiker's Guide to Nucleocytoplasmic Trafficking in Neurodegeneration.
Stephen Moore, Benjamin E Rabichow, Rita Sattler. Neurochem Res 2020
7

Recognition of expanded GGGGCC hexanucleotide repeat by synthetic ligand through interhelical binding.
Yihuan Lu, Chikara Dohno, Kazuhiko Nakatani. Biochem Biophys Res Commun 2020
1

Reduced C9ORF72 function exacerbates gain of toxicity from ALS/FTD-causing repeat expansion in C9orf72.
Qiang Zhu, Jie Jiang, Tania F Gendron, Melissa McAlonis-Downes, Lulin Jiang, Amy Taylor, Sandra Diaz Garcia, Somasish Ghosh Dastidar, Maria J Rodriguez, Patrick King,[...]. Nat Neurosci 2020
55

Divergence, Convergence, and Therapeutic Implications: A Cell Biology Perspective of C9ORF72-ALS/FTD.
Xiaoqiang Tang, Arturo Toro, Sahana T G, Junli Gao, Jessica Chalk, Björn Oskarsson, Ke Zhang. Mol Neurodegener 2020
9

Arginine-rich dipeptide-repeat proteins as phase disruptors in C9-ALS/FTD.
Hana M Odeh, James Shorter. Emerg Top Life Sci 2020
9

G4C2 Repeat RNA Initiates a POM121-Mediated Reduction in Specific Nucleoporins in C9orf72 ALS/FTD.
Alyssa N Coyne, Benjamin L Zaepfel, Lindsey Hayes, Boris Fitchman, Yuval Salzberg, En-Ching Luo, Kelly Bowen, Hannah Trost, Stefan Aigner, Frank Rigo,[...]. Neuron 2020
15

C9orf72-associated SMCR8 protein binds in the ubiquitin pathway and with proteins linked with neurological disease.
John L Goodier, Alisha O Soares, Gavin C Pereira, Lauren R DeVine, Laura Sanchez, Robert N Cole, Jose Luis García-Pérez. Acta Neuropathol Commun 2020
6

Multifaceted Genes in Amyotrophic Lateral Sclerosis-Frontotemporal Dementia.
Ramya Ranganathan, Shaila Haque, Kayesha Coley, Stephanie Shepheard, Johnathan Cooper-Knock, Janine Kirby. Front Neurosci 2020
4

RNA-mediated toxicity in C9orf72 ALS and FTD.
Zachary T McEachin, Janani Parameswaran, Nisha Raj, Gary J Bassell, Jie Jiang. Neurobiol Dis 2020
4

Role of the C9ORF72 Gene in the Pathogenesis of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia.
Zongbing Hao, Rui Wang, Haigang Ren, Guanghui Wang. Neurosci Bull 2020
1

Development of LNA Gapmer Oligonucleotide-Based Therapy for ALS/FTD Caused by the C9orf72 Repeat Expansion.
Chaitra Sathyaprakash, Raquel Manzano, Miguel A Varela, Yasumasa Hashimoto, Matthew J A Wood, Kevin Talbot, Yoshitsugu Aoki. Methods Mol Biol 2020
0

C9orf72 loss-of-function: a trivial, stand-alone or additive mechanism in C9 ALS/FTD?
Elke Braems, Bart Swinnen, Ludo Van Den Bosch. Acta Neuropathol 2020
7

C9orf72 poly(GR) aggregation induces TDP-43 proteinopathy.
Casey N Cook, Yanwei Wu, Hana M Odeh, Tania F Gendron, Karen Jansen-West, Giulia Del Rosso, Mei Yue, Peizhou Jiang, Edward Gomes, Jimei Tong,[...]. Sci Transl Med 2020
23

ALS Genetics: Gains, Losses, and Implications for Future Therapies.
Garam Kim, Olivia Gautier, Eduardo Tassoni-Tsuchida, X Rosa Ma, Aaron D Gitler. Neuron 2020
37

Insights into disease mechanisms and potential therapeutics for C9orf72-related amyotrophic lateral sclerosis/frontotemporal dementia.
Delia Gagliardi, Gianluca Costamagna, Michela Taiana, Luca Andreoli, Fabio Biella, Margherita Bersani, Nereo Bresolin, Giacomo Pietro Comi, Stefania Corti. Ageing Res Rev 2020
1

Modelling C9orf72-Related Amyotrophic Lateral Sclerosis in Zebrafish.
Gabrielle Fortier, Zoé Butti, Shunmoogum A Patten. Biomedicines 2020
3

BV-2 Microglial Cells Overexpressing C9orf72 Hexanucleotide Repeat Expansion Produce DPR Proteins and Show Normal Functionality but No RNA Foci.
Hannah Rostalski, Tomi Hietanen, Stina Leskelä, Andrea Behánová, Ali Abdollahzadeh, Rebekka Wittrahm, Petra Mäkinen, Nadine Huber, Dorit Hoffmann, Eino Solje,[...]. Front Neurol 2020
1