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List of shared articles
Times cited
IQCELL: A platform for predicting the effect of gene perturbations on developmental trajectories using single-cell RNA-seq data.
Tiam Heydari, Matthew A Langley, Cynthia L Fisher, Daniel Aguilar-Hidalgo, Shreya Shukla, Ayako Yachie-Kinoshita, Michael Hughes, Kelly M McNagny, Peter W Zandstra. PLoS Comput Biol 2022
Tiam Heydari, Matthew A Langley, Cynthia L Fisher, Daniel Aguilar-Hidalgo, Shreya Shukla, Ayako Yachie-Kinoshita, Michael Hughes, Kelly M McNagny, Peter W Zandstra. PLoS Comput Biol 2022
Human induced-T-to-natural killer cells have potent anti-tumour activities.
Zhiwu Jiang, Le Qin, Yuou Tang, Rui Liao, Jingxuan Shi, Bingjia He, Shanglin Li, Diwei Zheng, Yuanbin Cui, Qiting Wu,[...]. Biomark Res 2022
Zhiwu Jiang, Le Qin, Yuou Tang, Rui Liao, Jingxuan Shi, Bingjia He, Shanglin Li, Diwei Zheng, Yuanbin Cui, Qiting Wu,[...]. Biomark Res 2022
Single-cell deletion analyses show control of pro-T cell developmental speed and pathways by Tcf7, Spi1, Gata3, Bcl11a, Erg, and Bcl11b.
Wen Zhou, Fan Gao, Maile Romero-Wolf, Suin Jo, Ellen V Rothenberg. Sci Immunol 2022
Wen Zhou, Fan Gao, Maile Romero-Wolf, Suin Jo, Ellen V Rothenberg. Sci Immunol 2022
Notch signaling at the crossroads of innate and adaptive immunity.
Ashley Vanderbeck, Ivan Maillard. J Leukoc Biol 2021
Ashley Vanderbeck, Ivan Maillard. J Leukoc Biol 2021
Exploring the stage-specific roles of Tcf-1 in T cell development and malignancy at single-cell resolution.
Fang Wang, Zhihong Qi, Yingpeng Yao, Guotao Yu, Tao Feng, Tianyan Zhao, Hai-Hui Xue, Yaofeng Zhao, Peng Jiang, Li Bao,[...]. Cell Mol Immunol 2021
Fang Wang, Zhihong Qi, Yingpeng Yao, Guotao Yu, Tao Feng, Tianyan Zhao, Hai-Hui Xue, Yaofeng Zhao, Peng Jiang, Li Bao,[...]. Cell Mol Immunol 2021
How transcription factors drive choice of the T cell fate.
Hiroyuki Hosokawa, Ellen V Rothenberg. Nat Rev Immunol 2021
Hiroyuki Hosokawa, Ellen V Rothenberg. Nat Rev Immunol 2021
Multi-scale Dynamical Modeling of T Cell Development from an Early Thymic Progenitor State to Lineage Commitment.
Victor Olariu, Mary A Yui, Pawel Krupinski, Wen Zhou, Julia Deichmann, Emil Andersson, Ellen V Rothenberg, Carsten Peterson. Cell Rep 2021
Victor Olariu, Mary A Yui, Pawel Krupinski, Wen Zhou, Julia Deichmann, Emil Andersson, Ellen V Rothenberg, Carsten Peterson. Cell Rep 2021
Logic and lineage impacts on functional transcription factor deployment for T-cell fate commitment.
Ellen V Rothenberg. Biophys J 2021
Ellen V Rothenberg. Biophys J 2021
Deregulation of enhancer structure, function, and dynamics in acute lymphoblastic leukemia.
Laura Belver, Robert Albero, Adolfo A Ferrando. Trends Immunol 2021
Laura Belver, Robert Albero, Adolfo A Ferrando. Trends Immunol 2021
Oncogenic cooperation between TCF7-SPI1 and NRAS(G12D) requires β-catenin activity to drive T-cell acute lymphoblastic leukemia.
Quentin Van Thillo, Jolien De Bie, Janith A Seneviratne, Sofie Demeyer, Sofia Omari, Anushree Balachandran, Vicki Zhai, Wai L Tam, Bram Sweron, Ellen Geerdens,[...]. Nat Commun 2021
Quentin Van Thillo, Jolien De Bie, Janith A Seneviratne, Sofie Demeyer, Sofia Omari, Anushree Balachandran, Vicki Zhai, Wai L Tam, Bram Sweron, Ellen Geerdens,[...]. Nat Commun 2021
Delineating spatiotemporal and hierarchical development of human fetal innate lymphoid cells.
Chen Liu, Yandong Gong, Han Zhang, Hua Yang, Yang Zeng, Zhilei Bian, Qian Xin, Zhijie Bai, Man Zhang, Jian He,[...]. Cell Res 2021
Chen Liu, Yandong Gong, Han Zhang, Hua Yang, Yang Zeng, Zhilei Bian, Qian Xin, Zhijie Bai, Man Zhang, Jian He,[...]. Cell Res 2021
ZBTB Transcription Factors: Key Regulators of the Development, Differentiation and Effector Function of T Cells.
Zhong-Yan Cheng, Ting-Ting He, Xiao-Ming Gao, Ying Zhao, Jun Wang. Front Immunol 2021
Zhong-Yan Cheng, Ting-Ting He, Xiao-Ming Gao, Ying Zhao, Jun Wang. Front Immunol 2021
LMO2 is essential to maintain the ability of progenitors to differentiate into T-cell lineage in mice.
Ken-Ichi Hirano, Hiroyuki Hosokawa, Maria Koizumi, Yusuke Endo, Takashi Yahata, Kiyoshi Ando, Katsuto Hozumi. Elife 2021
Ken-Ichi Hirano, Hiroyuki Hosokawa, Maria Koizumi, Yusuke Endo, Takashi Yahata, Kiyoshi Ando, Katsuto Hozumi. Elife 2021
Chromatin-Modifying Enzymes in T Cell Development.
Michael J Shapiro, Virginia Smith Shapiro. Annu Rev Immunol 2020
Michael J Shapiro, Virginia Smith Shapiro. Annu Rev Immunol 2020
Integrated scRNA-Seq Identifies Human Postnatal Thymus Seeding Progenitors and Regulatory Dynamics of Differentiating Immature Thymocytes.
Marieke Lavaert, Kai Ling Liang, Niels Vandamme, Jong-Eun Park, Juliette Roels, Monica S Kowalczyk, Bo Li, Orr Ashenberg, Marcin Tabaka, Danielle Dionne,[...]. Immunity 2020
Marieke Lavaert, Kai Ling Liang, Niels Vandamme, Jong-Eun Park, Juliette Roels, Monica S Kowalczyk, Bo Li, Orr Ashenberg, Marcin Tabaka, Danielle Dionne,[...]. Immunity 2020
Logical modeling of cell fate specification-Application to T cell commitment.
Elisabetta Cacace, Samuel Collombet, Denis Thieffry. Curr Top Dev Biol 2020
Elisabetta Cacace, Samuel Collombet, Denis Thieffry. Curr Top Dev Biol 2020
ARID1a Associates with Lymphoid-Restricted Transcription Factors and Has an Essential Role in T Cell Development.
Audrey Astori, Johanna Tingvall-Gustafsson, Jacob Kuruvilla, Etienne Coyaud, Estelle M N Laurent, Maria Sunnerhagen, Josefine Åhsberg, Jonas Ungerbäck, Tobias Strid, Mikael Sigvardsson,[...]. J Immunol 2020
Audrey Astori, Johanna Tingvall-Gustafsson, Jacob Kuruvilla, Etienne Coyaud, Estelle M N Laurent, Maria Sunnerhagen, Josefine Åhsberg, Jonas Ungerbäck, Tobias Strid, Mikael Sigvardsson,[...]. J Immunol 2020
Notch2 complements Notch1 to mediate inductive signaling that initiates early T cell development.
Maile Romero-Wolf, Boyoung Shin, Wen Zhou, Maria Koizumi, Ellen V Rothenberg, Hiroyuki Hosokawa. J Cell Biol 2020
Maile Romero-Wolf, Boyoung Shin, Wen Zhou, Maria Koizumi, Ellen V Rothenberg, Hiroyuki Hosokawa. J Cell Biol 2020
Mechanisms of Action of Hematopoietic Transcription Factor PU.1 in Initiation of T-Cell Development.
Ellen V Rothenberg, Hiroyuki Hosokawa, Jonas Ungerbäck. Front Immunol 2019
Ellen V Rothenberg, Hiroyuki Hosokawa, Jonas Ungerbäck. Front Immunol 2019
An enriched network motif family regulates multistep cell fate transitions with restricted reversibility.
Yujie Ye, Xin Kang, Jordan Bailey, Chunhe Li, Tian Hong. PLoS Comput Biol 2019
Yujie Ye, Xin Kang, Jordan Bailey, Chunhe Li, Tian Hong. PLoS Comput Biol 2019
Programming for T-lymphocyte fates: modularity and mechanisms.
Ellen V Rothenberg. Genes Dev 2019
Ellen V Rothenberg. Genes Dev 2019
Single-Cell RNA Sequencing Resolves Spatiotemporal Development of Pre-thymic Lymphoid Progenitors and Thymus Organogenesis in Human Embryos.
Yang Zeng, Chen Liu, Yandong Gong, Zhijie Bai, Siyuan Hou, Jian He, Zhilei Bian, Zongcheng Li, Yanli Ni, Jing Yan,[...]. Immunity 2019
Yang Zeng, Chen Liu, Yandong Gong, Zhijie Bai, Siyuan Hou, Jian He, Zhilei Bian, Zongcheng Li, Yanli Ni, Jing Yan,[...]. Immunity 2019
Single-Cell Analysis Reveals Regulatory Gene Expression Dynamics Leading to Lineage Commitment in Early T Cell Development.
Wen Zhou, Mary A Yui, Brian A Williams, Jina Yun, Barbara J Wold, Long Cai, Ellen V Rothenberg. Cell Syst 2019
Wen Zhou, Mary A Yui, Brian A Williams, Jina Yun, Barbara J Wold, Long Cai, Ellen V Rothenberg. Cell Syst 2019
Dynamic control of the T-cell specification gene regulatory network.
Ellen V Rothenberg. Curr Opin Syst Biol 2019
Ellen V Rothenberg. Curr Opin Syst Biol 2019
Cytokines, Transcription Factors, and the Initiation of T-Cell Development.
Hiroyuki Hosokawa, Ellen V Rothenberg. Cold Spring Harb Perspect Biol 2018
Hiroyuki Hosokawa, Ellen V Rothenberg. Cold Spring Harb Perspect Biol 2018