A citation-based method for searching scientific literature

Stephanie May, Daniel Hornburg, Martin H Schludi, Thomas Arzberger, Kristin Rentzsch, Benjamin M Schwenk, Friedrich A Grässer, Kohji Mori, Elisabeth Kremmer, Julia Banzhaf-Strathmann, Matthias Mann, Felix Meissner, Dieter Edbauer. Acta Neuropathol 2014
Times Cited: 187

Tao Zu, Yuanjing Liu, Monica Bañez-Coronel, Tammy Reid, Olga Pletnikova, Jada Lewis, Timothy M Miller, Matthew B Harms, Annet E Falchook, S H Subramony, Lyle W Ostrow, Jeffrey D Rothstein, Juan C Troncoso, Laura P W Ranum. Proc Natl Acad Sci U S A 2013
Times Cited: 458

List of shared articles

Times cited

Glial Cell Dysfunction in C9orf72-Related Amyotrophic Lateral Sclerosis and Frontotemporal Dementia.
Mehdi Ghasemi, Kiandokht Keyhanian, Catherine Douthwright. Cells 2021

The progress in C9orf72 research: ALS/FTD pathogenesis, functions and structure.
Lan Jiang, Tizhong Zhang, Kefeng Lu, Shiqian Qi. Small GTPases 2021

Emerging Perspectives on Dipeptide Repeat Proteins in C9ORF72 ALS/FTD.
Alexander Schmitz, João Pinheiro Marques, Irina Oertig, Niran Maharjan, Smita Saxena. Front Cell Neurosci 2021

The Cryo-EM Effect: Structural Biology of Neurodegenerative Disease Proteostasis Factors.
Benjamin C Creekmore, Yi-Wei Chang, Edward B Lee. J Neuropathol Exp Neurol 2021

Molecular mechanisms underlying nucleotide repeat expansion disorders.
Indranil Malik, Chase P Kelley, Eric T Wang, Peter K Todd. Nat Rev Mol Cell Biol 2021

Multiple pathways of toxicity induced by C9orf72 dipeptide repeat aggregates and G4C2 RNA in a cellular model.
Frédéric Frottin, Manuela Pérez-Berlanga, F Ulrich Hartl, Mark S Hipp. Elife 2021

The Skeletal Muscle Emerges as a New Disease Target in Amyotrophic Lateral Sclerosis.
Oihane Pikatza-Menoio, Amaia Elicegui, Xabier Bengoetxea, Neia Naldaiz-Gastesi, Adolfo López de Munain, Gorka Gerenu, Francisco Javier Gil-Bea, Sonia Alonso-Martín. J Pers Med 2021

The porphyrin TMPyP4 inhibits elongation during the noncanonical translation of the FTLD/ALS-associated GGGGCC repeat in the C9orf72 gene.
Kohji Mori, Shiho Gotoh, Tomoko Yamashita, Ryota Uozumi, Yuya Kawabe, Shinji Tagami, Frits Kamp, Brigitte Nuscher, Dieter Edbauer, Christian Haass,[...]. J Biol Chem 2021

Elucidating the Role of Cerebellar Synaptic Dysfunction in C9orf72-ALS/FTD - a Systematic Review and Meta-Analysis.
Aleksandra Kaliszewska, Joseph Allison, Tarik-Tarkan Col, Christopher Shaw, Natalia Arias. Cerebellum 2021

Measuring and Interpreting Nuclear Transport in Neurodegenerative Disease-The Example of C9orf72 ALS.
Marije F W Semmelink, Anton Steen, Liesbeth M Veenhoff. Int J Mol Sci 2021

SRSF protein kinase 1 modulates RAN translation and suppresses CGG repeat toxicity.
Indranil Malik, Yi-Ju Tseng, Shannon E Wright, Kristina Zheng, Prithika Ramaiyer, Katelyn M Green, Peter K Todd. EMBO Mol Med 2021

A C. elegans model of C9orf72-associated ALS/FTD uncovers a conserved role for eIF2D in RAN translation.
Yoshifumi Sonobe, Jihad Aburas, Gopinath Krishnan, Andrew C Fleming, Ghanashyam Ghadge, Priota Islam, Eleanor C Warren, Yuanzheng Gu, Mark W Kankel, André E X Brown,[...]. Nat Commun 2021

Antibody Therapy Targeting RAN Proteins Rescues C9 ALS/FTD Phenotypes in C9orf72 Mouse Model.
Lien Nguyen, Fabio Montrasio, Amrutha Pattamatta, Solaleh Khoramian Tusi, Olgert Bardhi, Kevin D Meyer, Lindsey Hayes, Katsuya Nakamura, Monica Banez-Coronel, Alyssa Coyne,[...]. Neuron 2020

Reduced autophagy upon C9ORF72 loss synergizes with dipeptide repeat protein toxicity in G4C2 repeat expansion disorders.
Manon Boivin, Véronique Pfister, Angeline Gaucherot, Frank Ruffenach, Luc Negroni, Chantal Sellier, Nicolas Charlet-Berguerand. EMBO J 2020

The clinical trial landscape in amyotrophic lateral sclerosis-Past, present, and future.
Heike J Wobst, Korrie L Mack, Dean G Brown, Nicholas J Brandon, James Shorter. Med Res Rev 2020

Nucleocytoplasmic Proteomic Analysis Uncovers eRF1 and Nonsense-Mediated Decay as Modifiers of ALS/FTD C9orf72 Toxicity.
Juan A Ortega, Elizabeth L Daley, Sukhleen Kour, Marisa Samani, Liana Tellez, Haley S Smith, Elizabeth A Hall, Y Taylan Esengul, Yung-Hsu Tsai, Tania F Gendron,[...]. Neuron 2020

Arginine in C9ORF72 Dipolypeptides Mediates Promiscuous Proteome Binding and Multiple Modes of Toxicity.
Mona Radwan, Ching-Seng Ang, Angelique R Ormsby, Dezerae Cox, James C Daly, Gavin E Reid, Danny M Hatters. Mol Cell Proteomics 2020

C9orf72 arginine-rich dipeptide repeat proteins disrupt karyopherin-mediated nuclear import.
Lindsey R Hayes, Lauren Duan, Kelly Bowen, Petr Kalab, Jeffrey D Rothstein. Elife 2020

Cell-to-cell transmission of C9orf72 poly-(Gly-Ala) triggers key features of ALS/FTD.
Bahram Khosravi, Kathrine D LaClair, Henrick Riemenschneider, Qihui Zhou, Frédéric Frottin, Nikola Mareljic, Mareike Czuppa, Daniel Farny, Hannelore Hartmann, Meike Michaelsen,[...]. EMBO J 2020

Synaptic dysfunction induced by glycine-alanine dipeptides in C9orf72-ALS/FTD is rescued by SV2 replenishment.
Brigid K Jensen, Martin H Schuldi, Kevin McAvoy, Katelyn A Russell, Ashley Boehringer, Bridget M Curran, Karthik Krishnamurthy, Xinmei Wen, Thomas Westergard, Le Ma,[...]. EMBO Mol Med 2020

Divergence, Convergence, and Therapeutic Implications: A Cell Biology Perspective of C9ORF72-ALS/FTD.
Xiaoqiang Tang, Arturo Toro, Sahana T G, Junli Gao, Jessica Chalk, Björn Oskarsson, Ke Zhang. Mol Neurodegener 2020

Congenic expression of poly-GA but not poly-PR in mice triggers selective neuron loss and interferon responses found in C9orf72 ALS.
Katherine D LaClair, Qihui Zhou, Meike Michaelsen, Benedikt Wefers, Monika S Brill, Aleksandar Janjic, Birgit Rathkolb, Daniel Farny, Mikolaj Cygan, Martin Hrabe de Angelis,[...]. Acta Neuropathol 2020

Arginine-rich dipeptide-repeat proteins as phase disruptors in C9-ALS/FTD.
Hana M Odeh, James Shorter. Emerg Top Life Sci 2020

Phase Separation of Toxic Dipeptide Repeat Proteins Related to C9orf72 ALS/FTD.
Hamidreza Jafarinia, Erik van der Giessen, Patrick R Onck. Biophys J 2020

Multifaceted Genes in Amyotrophic Lateral Sclerosis-Frontotemporal Dementia.
Ramya Ranganathan, Shaila Haque, Kayesha Coley, Stephanie Shepheard, Johnathan Cooper-Knock, Janine Kirby. Front Neurosci 2020

The carboxyl termini of RAN translated GGGGCC nucleotide repeat expansions modulate toxicity in models of ALS/FTD.
Fang He, Brittany N Flores, Amy Krans, Michelle Frazer, Sam Natla, Sarjina Niraula, Olamide Adefioye, Sami J Barmada, Peter K Todd. Acta Neuropathol Commun 2020

The RNA exosome complex degrades expanded hexanucleotide repeat RNA in C9orf72 FTLD/ALS.
Yuya Kawabe, Kohji Mori, Tomoko Yamashita, Shiho Gotoh, Manabu Ikeda. EMBO J 2020

Role of the C9ORF72 Gene in the Pathogenesis of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia.
Zongbing Hao, Rui Wang, Haigang Ren, Guanghui Wang. Neurosci Bull 2020

ALS Genetics: Gains, Losses, and Implications for Future Therapies.
Garam Kim, Olivia Gautier, Eduardo Tassoni-Tsuchida, X Rosa Ma, Aaron D Gitler. Neuron 2020

BV-2 Microglial Cells Overexpressing C9orf72 Hexanucleotide Repeat Expansion Produce DPR Proteins and Show Normal Functionality but No RNA Foci.
Hannah Rostalski, Tomi Hietanen, Stina Leskelä, Andrea Behánová, Ali Abdollahzadeh, Rebekka Wittrahm, Petra Mäkinen, Nadine Huber, Dorit Hoffmann, Eino Solje,[...]. Front Neurol 2020

C9orf72-FTD/ALS pathogenesis: evidence from human neuropathological studies.
Sarat C Vatsavayai, Alissa L Nana, Jennifer S Yokoyama, William W Seeley. Acta Neuropathol 2019

Review: Modelling the pathology and behaviour of frontotemporal dementia.
D A Solomon, J C Mitchell, M-T Salcher-Konrad, C A Vance, S Mizielinska. Neuropathol Appl Neurobiol 2019

C9orf72 arginine-rich dipeptide proteins interact with ribosomal proteins in vivo to induce a toxic translational arrest that is rescued by eIF1A.
Thomas G Moens, Teresa Niccoli, Katherine M Wilson, Magda L Atilano, Nicol Birsa, Lauren M Gittings, Benedikt V Holbling, Miranda C Dyson, Annora Thoeng, Jacob Neeves,[...]. Acta Neuropathol 2019

Repeat-associated non-AUG translation in C9orf72-ALS/FTD is driven by neuronal excitation and stress.
Thomas Westergard, Kevin McAvoy, Katelyn Russell, Xinmei Wen, Yu Pang, Brandie Morris, Piera Pasinelli, Davide Trotti, Aaron Haeusler. EMBO Mol Med 2019

Translational control in brain pathologies: biological significance and therapeutic opportunities.
Alberto Delaidelli, Asad Jan, Jochen Herms, Poul H Sorensen. Acta Neuropathol 2019

Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathy.
Jeannie Chew, Casey Cook, Tania F Gendron, Karen Jansen-West, Giulia Del Rosso, Lillian M Daughrity, Monica Castanedes-Casey, Aishe Kurti, Jeannette N Stankowski, Matthew D Disney,[...]. Mol Neurodegener 2019

Molecular Mechanisms of Neurodegeneration Related to C9orf72 Hexanucleotide Repeat Expansion.
Mirjana Babić Leko, Vera Župunski, Jason Kirincich, Dinko Smilović, Tibor Hortobágyi, Patrick R Hof, Goran Šimić. Behav Neurol 2019

Repeat-Associated Non-ATG Translation: Molecular Mechanisms and Contribution to Neurological Disease.
Lien Nguyen, John Douglas Cleary, Laura P W Ranum. Annu Rev Neurosci 2019

Repeat-associated non-AUG (RAN) translation: insights from pathology.
Monica Banez-Coronel, Laura P W Ranum. Lab Invest 2019

ADAR2 mislocalization and widespread RNA editing aberrations in C9orf72-mediated ALS/FTD.
Stephen Moore, Eric Alsop, Ileana Lorenzini, Alexander Starr, Benjamin E Rabichow, Emily Mendez, Jennifer L Levy, Camelia Burciu, Rebecca Reiman, Jeannie Chew,[...]. Acta Neuropathol 2019

Molecular dynamics study of structure, folding, and aggregation of poly-glycine-alanine (Poly-GA).
Size Zheng, Ali Sahimi, Katherine S Shing, Muhammad Sahimi. J Chem Phys 2019

Disruption of RNA Metabolism in Neurological Diseases and Emerging Therapeutic Interventions.
Julia K Nussbacher, Ricardos Tabet, Gene W Yeo, Clotilde Lagier-Tourenne. Neuron 2019

Astrocytes and Microglia as Potential Contributors to the Pathogenesis of C9orf72 Repeat Expansion-Associated FTLD and ALS.
Hannah Rostalski, Stina Leskelä, Nadine Huber, Kasper Katisko, Antti Cajanus, Eino Solje, Mikael Marttinen, Teemu Natunen, Anne M Remes, Mikko Hiltunen,[...]. Front Neurosci 2019

Motor dysfunction and neurodegeneration in a C9orf72 mouse line expressing poly-PR.
Zongbing Hao, Liu Liu, Zhouteng Tao, Rui Wang, Haigang Ren, Hongyang Sun, Zixuan Lin, Zhixiong Zhang, Chenchen Mu, Jiawei Zhou,[...]. Nat Commun 2019

High-throughput screening yields several small-molecule inhibitors of repeat-associated non-AUG translation.
Katelyn M Green, Udit J Sheth, Brittany N Flores, Shannon E Wright, Alexandra B Sutter, Michael G Kearse, Sami J Barmada, Magdalena I Ivanova, Peter K Todd. J Biol Chem 2019