A citation-based method for searching scientific literature

Isoform-specific antibodies reveal distinct subcellular localizations of C9orf72 in amyotrophic lateral sclerosis.
Shangxi Xiao, Laura MacNair, Philip McGoldrick, Paul M McKeever, Jesse R McLean, Ming Zhang, Julia Keith, Lorne Zinman, Ekaterina Rogaeva, Janice Robertson. Ann Neurol 2015
Times Cited: 100



Hexanucleotide repeats in ALS/FTD form length-dependent RNA foci, sequester RNA binding proteins, and are neurotoxic.
Youn-Bok Lee, Han-Jou Chen, João N Peres, Jorge Gomez-Deza, Jan Attig, Maja Stalekar, Claire Troakes, Agnes L Nishimura, Emma L Scotter, Caroline Vance, Yoshitsugu Adachi, Valentina Sardone, Jack W Miller, Bradley N Smith, Jean-Marc Gallo, Jernej Ule, Frank Hirth, Boris Rogelj, Corinne Houart, Christopher E Shaw. Cell Rep 2013
Times Cited: 315




List of shared articles



Times cited

C9orf72-mediated ALS and FTD: multiple pathways to disease.
Rubika Balendra, Adrian M Isaacs. Nat Rev Neurol 2018
247

Genetics insight into the amyotrophic lateral sclerosis/frontotemporal dementia spectrum.
Ai-Ling Ji, Xia Zhang, Wei-Wei Chen, Wen-Juan Huang. J Med Genet 2017
52

RNA toxicity in non-coding repeat expansion disorders.
Bart Swinnen, Wim Robberecht, Ludo Van Den Bosch. EMBO J 2020
81

Retention of hexanucleotide repeat-containing intron in C9orf72 mRNA: implications for the pathogenesis of ALS/FTD.
Michael Niblock, Bradley N Smith, Youn-Bok Lee, Valentina Sardone, Simon Topp, Claire Troakes, Safa Al-Sarraj, Claire S Leblond, Patrick A Dion, Guy A Rouleau,[...]. Acta Neuropathol Commun 2016
34

RNA Misprocessing in C9orf72-Linked Neurodegeneration.
Holly V Barker, Michael Niblock, Youn-Bok Lee, Christopher E Shaw, Jean-Marc Gallo. Front Cell Neurosci 2017
24

Insights into the pathogenic mechanisms of Chromosome 9 open reading frame 72 (C9orf72) repeat expansions.
Tiffany W Todd, Leonard Petrucelli. J Neurochem 2016
48

Reduced autophagy upon C9ORF72 loss synergizes with dipeptide repeat protein toxicity in G4C2 repeat expansion disorders.
Manon Boivin, Véronique Pfister, Angeline Gaucherot, Frank Ruffenach, Luc Negroni, Chantal Sellier, Nicolas Charlet-Berguerand. EMBO J 2020
47

Modelling C9orf72-Related Amyotrophic Lateral Sclerosis in Zebrafish.
Gabrielle Fortier, Zoé Butti, Shunmoogum A Patten. Biomedicines 2020
5

Dynamic expression of the mouse orthologue of the human amyotropic lateral sclerosis associated gene C9orf72 during central nervous system development and neuronal differentiation.
Ross Ferguson, Eleni Serafeimidou-Pouliou, Vasanta Subramanian. J Anat 2016
4

C9ORF72: What It Is, What It Does, and Why It Matters.
Julie Smeyers, Elena-Gaia Banchi, Morwena Latouche. Front Cell Neurosci 2021
10

Genetic models of C9orf72: what is toxic?
Thomas G Moens, Linda Partridge, Adrian M Isaacs. Curr Opin Genet Dev 2017
35

Nuclear RNA foci from C9ORF72 expansion mutation form paraspeckle-like bodies.
Ana Bajc Česnik, Simona Darovic, Sonja Prpar Mihevc, Maja Štalekar, Mirjana Malnar, Helena Motaln, Youn-Bok Lee, Julija Mazej, Jure Pohleven, Markus Grosch,[...]. J Cell Sci 2019
19

Ablation of C9orf72 together with excitotoxicity induces ALS in rats.
Wei Dong, Yuanwu Ma, Feifei Guan, Xu Zhang, Wei Chen, Li Zhang, Lianfeng Zhang. FEBS J 2021
5

Novel antibodies reveal presynaptic localization of C9orf72 protein and reduced protein levels in C9orf72 mutation carriers.
Petra Frick, Chantal Sellier, Ian R A Mackenzie, Chieh-Yu Cheng, Julie Tahraoui-Bories, Cecile Martinat, R Jeroen Pasterkamp, Johannes Prudlo, Dieter Edbauer, Mustapha Oulad-Abdelghani,[...]. Acta Neuropathol Commun 2018
58

Inside out: the role of nucleocytoplasmic transport in ALS and FTLD.
Steven Boeynaems, Elke Bogaert, Philip Van Damme, Ludo Van Den Bosch. Acta Neuropathol 2016
72

C9ORF72 hexanucleotide repeat exerts toxicity in a stable, inducible motor neuronal cell model, which is rescued by partial depletion of Pten.
Matthew J Stopford, Adrian Higginbottom, Guillaume M Hautbergue, Johnathan Cooper-Knock, Padraig J Mulcahy, Kurt J De Vos, Alan E Renton, Hannah Pliner, Andrea Calvo, Adriano Chio,[...]. Hum Mol Genet 2017
17

Altered Phase Separation and Cellular Impact in C9orf72-Linked ALS/FTD.
Daniel A Solomon, Rebekah Smikle, Matthew J Reid, Sarah Mizielinska. Front Cell Neurosci 2021
6

Disease Mechanisms of C9ORF72 Repeat Expansions.
Tania F Gendron, Leonard Petrucelli. Cold Spring Harb Perspect Med 2018
51

Prion-like propagation as a pathogenic principle in frontotemporal dementia.
Eva-Maria Hock, Magdalini Polymenidou. J Neurochem 2016
29

Pathogenic Mechanisms and Therapy Development for C9orf72 Amyotrophic Lateral Sclerosis/Frontotemporal Dementia.
Jie Jiang, John Ravits. Neurotherapeutics 2019
20

Modeling the C9ORF72 repeat expansion mutation using human induced pluripotent stem cells.
Bhuvaneish T Selvaraj, Matthew R Livesey, Siddharthan Chandran. Brain Pathol 2017
7

The Hitchhiker's Guide to Nucleocytoplasmic Trafficking in Neurodegeneration.
Stephen Moore, Benjamin E Rabichow, Rita Sattler. Neurochem Res 2020
11

Knock in of a hexanucleotide repeat expansion in the C9orf72 gene induces ALS in rats.
Wei Dong, Li Zhang, Caixian Sun, Xiang Gao, Feifei Guan, Jing Li, Wei Chen, Yuanwu Ma, Lianfeng Zhang. Animal Model Exp Med 2020
10

Dysregulated axonal RNA translation in amyotrophic lateral sclerosis.
Kyota Yasuda, Stavroula Mili. Wiley Interdiscip Rev RNA 2016
20

Synaptic dysfunction and altered excitability in C9ORF72 ALS/FTD.
Alexander Starr, Rita Sattler. Brain Res 2018
35

C9orf72-FTD/ALS pathogenesis: evidence from human neuropathological studies.
Sarat C Vatsavayai, Alissa L Nana, Jennifer S Yokoyama, William W Seeley. Acta Neuropathol 2019
35

Insights into C9ORF72-Related ALS/FTD from Drosophila and iPSC Models.
Yeliz Yuva-Aydemir, Sandra Almeida, Fen-Biao Gao. Trends Neurosci 2018
31

Pathogenic determinants and mechanisms of ALS/FTD linked to hexanucleotide repeat expansions in the C9orf72 gene.
Xinmei Wen, Thomas Westergard, Piera Pasinelli, Davide Trotti. Neurosci Lett 2017
27

Distinct neurological disorders with C9orf72 mutations: genetics, pathogenesis, and therapy.
Song Chi, Teng Jiang, Lan Tan, Jin-Tai Yu. Neurosci Biobehav Rev 2016
9

Sense-encoded poly-GR dipeptide repeat proteins correlate to neurodegeneration and uniquely co-localize with TDP-43 in dendrites of repeat-expanded C9orf72 amyotrophic lateral sclerosis.
Shahram Saberi, Jennifer E Stauffer, Jie Jiang, Sandra Diaz Garcia, Amy E Taylor, Derek Schulte, Takuya Ohkubo, Cheyenne L Schloffman, Marcus Maldonado, Michael Baughn,[...]. Acta Neuropathol 2018
100

Elucidating the Role of Cerebellar Synaptic Dysfunction in C9orf72-ALS/FTD - a Systematic Review and Meta-Analysis.
Aleksandra Kaliszewska, Joseph Allison, Tarik-Tarkan Col, Christopher Shaw, Natalia Arias. Cerebellum 2021
0

Unstable repeat expansions in neurodegenerative diseases: nucleocytoplasmic transport emerges on the scene.
Joana R Loureiro, Claudia L Oliveira, Isabel Silveira. Neurobiol Aging 2016
26

ADAR2 mislocalization and widespread RNA editing aberrations in C9orf72-mediated ALS/FTD.
Stephen Moore, Eric Alsop, Ileana Lorenzini, Alexander Starr, Benjamin E Rabichow, Emily Mendez, Jennifer L Levy, Camelia Burciu, Rebecca Reiman, Jeannie Chew,[...]. Acta Neuropathol 2019
27

Repeat length increases disease penetrance and severity in C9orf72 ALS/FTD BAC transgenic mice.
Amrutha Pattamatta, Lien Nguyen, Hailey R Olafson, Marina M Scotti, Lauren A Laboissonniere, Jared Richardson, J Andrew Berglund, Tao Zu, Eric T Wang, Laura P W Ranum. Hum Mol Genet 2021
4

C9orf72 ablation causes immune dysregulation characterized by leukocyte expansion, autoantibody production, and glomerulonephropathy in mice.
Amanda Atanasio, Vilma Decman, Derek White, Meg Ramos, Burcin Ikiz, Hoi-Ching Lee, Chia-Jen Siao, Susannah Brydges, Elizabeth LaRosa, Yu Bai,[...]. Sci Rep 2016
159

A C9orf72 ALS/FTD Ortholog Acts in Endolysosomal Degradation and Lysosomal Homeostasis.
Anna Corrionero, H Robert Horvitz. Curr Biol 2018
50

Insights into disease mechanisms and potential therapeutics for C9orf72-related amyotrophic lateral sclerosis/frontotemporal dementia.
Delia Gagliardi, Gianluca Costamagna, Michela Taiana, Luca Andreoli, Fabio Biella, Margherita Bersani, Nereo Bresolin, Giacomo Pietro Comi, Stefania Corti. Ageing Res Rev 2020
2

Dysregulated molecular pathways in amyotrophic lateral sclerosis-frontotemporal dementia spectrum disorder.
Fen-Biao Gao, Sandra Almeida, Rodrigo Lopez-Gonzalez. EMBO J 2017
103

Molecular Mechanisms of Neurodegeneration Related to C9orf72 Hexanucleotide Repeat Expansion.
Mirjana Babić Leko, Vera Župunski, Jason Kirincich, Dinko Smilović, Tibor Hortobágyi, Patrick R Hof, Goran Šimić. Behav Neurol 2019
28

The expanding biology of the C9orf72 nucleotide repeat expansion in neurodegenerative disease.
Aaron R Haeusler, Christopher J Donnelly, Jeffrey D Rothstein. Nat Rev Neurosci 2016
120

ALS Genetics, Mechanisms, and Therapeutics: Where Are We Now?
Rita Mejzini, Loren L Flynn, Ianthe L Pitout, Sue Fletcher, Steve D Wilton, P Anthony Akkari. Front Neurosci 2019
204

C9orf72 isoforms in Amyotrophic Lateral Sclerosis and Frontotemporal Lobar Degeneration.
Shangxi Xiao, Laura MacNair, Jesse McLean, Phillip McGoldrick, Paul McKeever, Serena Soleimani, Julia Keith, Lorne Zinman, Ekaterina Rogaeva, Janice Robertson. Brain Res 2016
30


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