A citation-based method for searching scientific literature

Ian R A Mackenzie, Petra Frick, Friedrich A Grässer, Tania F Gendron, Leonard Petrucelli, Neil R Cashman, Dieter Edbauer, Elisabeth Kremmer, Johannes Prudlo, Dirk Troost, Manuela Neumann. Acta Neuropathol 2015
Times Cited: 142



Alan E Renton, Elisa Majounie, Adrian Waite, Javier Simón-Sánchez, Sara Rollinson, J Raphael Gibbs, Jennifer C Schymick, Hannu Laaksovirta, John C van Swieten, Liisa Myllykangas, Hannu Kalimo, Anders Paetau, Yevgeniya Abramzon, Anne M Remes, Alice Kaganovich, Sonja W Scholz, Jamie Duckworth, Jinhui Ding, Daniel W Harmer, Dena G Hernandez, Janel O Johnson, Kin Mok, Mina Ryten, Danyah Trabzuni, Rita J Guerreiro, Richard W Orrell, James Neal, Alex Murray, Justin Pearson, Iris E Jansen, David Sondervan, Harro Seelaar, Derek Blake, Kate Young, Nicola Halliwell, Janis Bennion Callister, Greg Toulson, Anna Richardson, Alex Gerhard, Julie Snowden, David Mann, David Neary, Michael A Nalls, Terhi Peuralinna, Lilja Jansson, Veli-Matti Isoviita, Anna-Lotta Kaivorinne, Maarit Hölttä-Vuori, Elina Ikonen, Raimo Sulkava, Michael Benatar, Joanne Wuu, Adriano Chiò, Gabriella Restagno, Giuseppe Borghero, Mario Sabatelli, David Heckerman, Ekaterina Rogaeva, Lorne Zinman, Jeffrey D Rothstein, Michael Sendtner, Carsten Drepper, Evan E Eichler, Can Alkan, Ziedulla Abdullaev, Svetlana D Pack, Amalia Dutra, Evgenia Pak, John Hardy, Andrew Singleton, Nigel M Williams, Peter Heutink, Stuart Pickering-Brown, Huw R Morris, Pentti J Tienari, Bryan J Traynor. Neuron 2011
Times Cited: 2630




List of shared articles



Times cited

Molecular Dynamics Study of Structure, Folding, and Aggregation of Poly-PR and Poly-GR Proteins.
Size Zheng, Ali Sahimi, Katherine S Shing, Muhammad Sahimi. Biophys J 2021
1

Inducible expression of human C9ORF72 36x G4C2 hexanucleotide repeats is sufficient to cause RAN translation and rapid muscular atrophy in mice.
F W Riemslagh, E C van der Toorn, R F M Verhagen, A Maas, L W J Bosman, R K Hukema, R Willemsen. Dis Model Mech 2021
2

p53 is a central regulator driving neurodegeneration caused by C9orf72 poly(PR).
Maya Maor-Nof, Zohar Shipony, Rodrigo Lopez-Gonzalez, Lisa Nakayama, Yong-Jie Zhang, Julien Couthouis, Jacob A Blum, Patricia A Castruita, Gabriel R Linares, Kai Ruan,[...]. Cell 2021
12

Emerging Perspectives on Dipeptide Repeat Proteins in C9ORF72 ALS/FTD.
Alexander Schmitz, João Pinheiro Marques, Irina Oertig, Niran Maharjan, Smita Saxena. Front Cell Neurosci 2021
0

C9orf72-derived arginine-containing dipeptide repeats associate with axonal transport machinery and impede microtubule-based motility.
Laura Fumagalli, Florence L Young, Steven Boeynaems, Mathias De Decker, Arpan R Mehta, Ann Swijsen, Raheem Fazal, Wenting Guo, Matthieu Moisse, Jimmy Beckers,[...]. Sci Adv 2021
6

Altered Phase Separation and Cellular Impact in C9orf72-Linked ALS/FTD.
Daniel A Solomon, Rebekah Smikle, Matthew J Reid, Sarah Mizielinska. Front Cell Neurosci 2021
0

UBQLN2-HSP70 axis reduces poly-Gly-Ala aggregates and alleviates behavioral defects in the C9ORF72 animal model.
Kejing Zhang, Ailian Wang, Keke Zhong, Shuyuan Qi, Chen Wei, Xiaoqiu Shu, Wen-Yo Tu, Wentao Xu, Congcong Xia, Yatao Xiao,[...]. Neuron 2021
1

C9ORF72: What It Is, What It Does, and Why It Matters.
Julie Smeyers, Elena-Gaia Banchi, Morwena Latouche. Front Cell Neurosci 2021
1

Autophagy and ALS: mechanistic insights and therapeutic implications.
Jason P Chua, Hortense De Calbiac, Edor Kabashi, Sami J Barmada. Autophagy 2021
1

Multiple pathways of toxicity induced by C9orf72 dipeptide repeat aggregates and G4C2 RNA in a cellular model.
Frédéric Frottin, Manuela Pérez-Berlanga, F Ulrich Hartl, Mark S Hipp. Elife 2021
0

Immunotherapies for Neurodegenerative Diseases.
Ibrahim Mortada, Raymond Farah, Sanaa Nabha, David M Ojcius, Youssef Fares, Wassim Y Almawi, Najwane Said Sadier. Front Neurol 2021
1

The porphyrin TMPyP4 inhibits elongation during the noncanonical translation of the FTLD/ALS-associated GGGGCC repeat in the C9orf72 gene.
Kohji Mori, Shiho Gotoh, Tomoko Yamashita, Ryota Uozumi, Yuya Kawabe, Shinji Tagami, Frits Kamp, Brigitte Nuscher, Dieter Edbauer, Christian Haass,[...]. J Biol Chem 2021
0

Elucidating the Role of Cerebellar Synaptic Dysfunction in C9orf72-ALS/FTD - a Systematic Review and Meta-Analysis.
Aleksandra Kaliszewska, Joseph Allison, Tarik-Tarkan Col, Christopher Shaw, Natalia Arias. Cerebellum 2021
0

Phase separation and toxicity of C9orf72 poly(PR) depends on alternate distribution of arginine.
Chen Chen, Yoshiaki Yamanaka, Koji Ueda, Peiying Li, Tamami Miyagi, Yuichiro Harada, Sayaka Tezuka, Satoshi Narumi, Masahiro Sugimoto, Masahiko Kuroda,[...]. J Cell Biol 2021
0

Measuring and Interpreting Nuclear Transport in Neurodegenerative Disease-The Example of C9orf72 ALS.
Marije F W Semmelink, Anton Steen, Liesbeth M Veenhoff. Int J Mol Sci 2021
0

All Roads Lead to Rome: Different Molecular Players Converge to Common Toxic Pathways in Neurodegeneration.
Shirel Argueti-Ostrovsky, Leenor Alfahel, Joy Kahn, Adrian Israelson. Cells 2021
0

RNA Deregulation in Amyotrophic Lateral Sclerosis: The Noncoding Perspective.
Pietro Laneve, Paolo Tollis, Elisa Caffarelli. Int J Mol Sci 2021
0

A C. elegans model of C9orf72-associated ALS/FTD uncovers a conserved role for eIF2D in RAN translation.
Yoshifumi Sonobe, Jihad Aburas, Gopinath Krishnan, Andrew C Fleming, Ghanashyam Ghadge, Priota Islam, Eleanor C Warren, Yuanzheng Gu, Mark W Kankel, André E X Brown,[...]. Nat Commun 2021
0

Nucleocytoplasmic transport defects in neurodegeneration - Cause or consequence?
Saskia Hutten, Dorothee Dormann. Semin Cell Dev Biol 2020
23

RNA toxicity in non-coding repeat expansion disorders.
Bart Swinnen, Wim Robberecht, Ludo Van Den Bosch. EMBO J 2020
66

Active poly-GA vaccination prevents microglia activation and motor deficits in a C9orf72 mouse model.
Qihui Zhou, Nikola Mareljic, Meike Michaelsen, Samira Parhizkar, Steffanie Heindl, Brigitte Nuscher, Daniel Farny, Mareike Czuppa, Carina Schludi, Alexander Graf,[...]. EMBO Mol Med 2020
14

Reduced autophagy upon C9ORF72 loss synergizes with dipeptide repeat protein toxicity in G4C2 repeat expansion disorders.
Manon Boivin, Véronique Pfister, Angeline Gaucherot, Frank Ruffenach, Luc Negroni, Chantal Sellier, Nicolas Charlet-Berguerand. EMBO J 2020
33

Innate Immunity: A Common Denominator between Neurodegenerative and Neuropsychiatric Diseases.
Fabiana Novellino, Valeria Saccà, Annalidia Donato, Paolo Zaffino, Maria Francesca Spadea, Marco Vismara, Biagio Arcidiacono, Natalia Malara, Ivan Presta, Giuseppe Donato. Int J Mol Sci 2020
29

Nucleocytoplasmic Proteomic Analysis Uncovers eRF1 and Nonsense-Mediated Decay as Modifiers of ALS/FTD C9orf72 Toxicity.
Juan A Ortega, Elizabeth L Daley, Sukhleen Kour, Marisa Samani, Liana Tellez, Haley S Smith, Elizabeth A Hall, Y Taylan Esengul, Yung-Hsu Tsai, Tania F Gendron,[...]. Neuron 2020
26


Cell-to-cell transmission of C9orf72 poly-(Gly-Ala) triggers key features of ALS/FTD.
Bahram Khosravi, Kathrine D LaClair, Henrick Riemenschneider, Qihui Zhou, Frédéric Frottin, Nikola Mareljic, Mareike Czuppa, Daniel Farny, Hannelore Hartmann, Meike Michaelsen,[...]. EMBO J 2020
17

Reduced C9ORF72 function exacerbates gain of toxicity from ALS/FTD-causing repeat expansion in C9orf72.
Qiang Zhu, Jie Jiang, Tania F Gendron, Melissa McAlonis-Downes, Lulin Jiang, Amy Taylor, Sandra Diaz Garcia, Somasish Ghosh Dastidar, Maria J Rodriguez, Patrick King,[...]. Nat Neurosci 2020
56

Synaptic dysfunction induced by glycine-alanine dipeptides in C9orf72-ALS/FTD is rescued by SV2 replenishment.
Brigid K Jensen, Martin H Schuldi, Kevin McAvoy, Katelyn A Russell, Ashley Boehringer, Bridget M Curran, Karthik Krishnamurthy, Xinmei Wen, Thomas Westergard, Le Ma,[...]. EMBO Mol Med 2020
9

Chimeric Peptide Species Contribute to Divergent Dipeptide Repeat Pathology in c9ALS/FTD and SCA36.
Zachary T McEachin, Tania F Gendron, Nisha Raj, María García-Murias, Anwesha Banerjee, Ryan H Purcell, Patricia J Ward, Tiffany W Todd, Megan E Merritt-Garza, Karen Jansen-West,[...]. Neuron 2020
15

Correction of amyotrophic lateral sclerosis related phenotypes in induced pluripotent stem cell-derived motor neurons carrying a hexanucleotide expansion mutation in C9orf72 by CRISPR/Cas9 genome editing using homology-directed repair.
Nidaa A Ababneh, Jakub Scaber, Rowan Flynn, Andrew Douglas, Paola Barbagallo, Ana Candalija, Martin R Turner, David Sims, Ruxandra Dafinca, Sally A Cowley,[...]. Hum Mol Genet 2020
6

Divergence, Convergence, and Therapeutic Implications: A Cell Biology Perspective of C9ORF72-ALS/FTD.
Xiaoqiang Tang, Arturo Toro, Sahana T G, Junli Gao, Jessica Chalk, Björn Oskarsson, Ke Zhang. Mol Neurodegener 2020
9

Arginine-rich dipeptide-repeat proteins as phase disruptors in C9-ALS/FTD.
Hana M Odeh, James Shorter. Emerg Top Life Sci 2020
10

RNA-mediated toxicity in C9orf72 ALS and FTD.
Zachary T McEachin, Janani Parameswaran, Nisha Raj, Gary J Bassell, Jie Jiang. Neurobiol Dis 2020
4


Role of the C9ORF72 Gene in the Pathogenesis of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia.
Zongbing Hao, Rui Wang, Haigang Ren, Guanghui Wang. Neurosci Bull 2020
1

C9orf72 poly(GR) aggregation induces TDP-43 proteinopathy.
Casey N Cook, Yanwei Wu, Hana M Odeh, Tania F Gendron, Karen Jansen-West, Giulia Del Rosso, Mei Yue, Peizhou Jiang, Edward Gomes, Jimei Tong,[...]. Sci Transl Med 2020
27


Insights into disease mechanisms and potential therapeutics for C9orf72-related amyotrophic lateral sclerosis/frontotemporal dementia.
Delia Gagliardi, Gianluca Costamagna, Michela Taiana, Luca Andreoli, Fabio Biella, Margherita Bersani, Nereo Bresolin, Giacomo Pietro Comi, Stefania Corti. Ageing Res Rev 2020
1


Nuclear Import Receptors Directly Bind to Arginine-Rich Dipeptide Repeat Proteins and Suppress Their Pathological Interactions.
Saskia Hutten, Sinem Usluer, Benjamin Bourgeois, Francesca Simonetti, Hana M Odeh, Charlotte M Fare, Mareike Czuppa, Marian Hruska-Plochan, Mario Hofweber, Magdalini Polymenidou,[...]. Cell Rep 2020
16

Review: Neuropathology of non-tau frontotemporal lobar degeneration.
M Neumann, I R A Mackenzie. Neuropathol Appl Neurobiol 2019
44

C9orf72-FTD/ALS pathogenesis: evidence from human neuropathological studies.
Sarat C Vatsavayai, Alissa L Nana, Jennifer S Yokoyama, William W Seeley. Acta Neuropathol 2019
29

Suppression of the yeast elongation factor Spt4 ortholog reduces expanded SCA36 GGCCUG repeat aggregation and cytotoxicity.
Natsumi Furuta, Setsuki Tsukagoshi, Kimitoshi Hirayanagi, Yoshio Ikeda. Brain Res 2019
5

Heterochromatin anomalies and double-stranded RNA accumulation underlie C9orf72 poly(PR) toxicity.
Yong-Jie Zhang, Lin Guo, Patrick K Gonzales, Tania F Gendron, Yanwei Wu, Karen Jansen-West, Aliesha D O'Raw, Sarah R Pickles, Mercedes Prudencio, Yari Carlomagno,[...]. Science 2019
82

Molecular Mechanisms of Neurodegeneration Related to C9orf72 Hexanucleotide Repeat Expansion.
Mirjana Babić Leko, Vera Župunski, Jason Kirincich, Dinko Smilović, Tibor Hortobágyi, Patrick R Hof, Goran Šimić. Behav Neurol 2019
25

HR23B pathology preferentially co-localizes with p62, pTDP-43 and poly-GA in C9ORF72-linked frontotemporal dementia and amyotrophic lateral sclerosis.
Frederike W Riemslagh, Hannes Lans, Harro Seelaar, Lies-Anne W F M Severijnen, Shamiram Melhem, Wim Vermeulen, Eleonora Aronica, R Jeroen Pasterkamp, John C van Swieten, Rob Willemsen. Acta Neuropathol Commun 2019
5

A Peptidylic Inhibitor for Neutralizing r(GGGGCC)exp-Associated Neurodegeneration in C9ALS-FTD.
Qian Zhang, Ying An, Zhefan Stephen Chen, Alex Chun Koon, Kwok-Fai Lau, Jacky Chi Ki Ngo, Ho Yin Edwin Chan. Mol Ther Nucleic Acids 2019
4

Repeat-associated non-AUG (RAN) translation: insights from pathology.
Monica Banez-Coronel, Laura P W Ranum. Lab Invest 2019
14

Molecular dynamics study of structure, folding, and aggregation of poly-glycine-alanine (Poly-GA).
Size Zheng, Ali Sahimi, Katherine S Shing, Muhammad Sahimi. J Chem Phys 2019
3

eIF4B and eIF4H mediate GR production from expanded G4C2 in a Drosophila model for C9orf72-associated ALS.
Lindsey D Goodman, Mercedes Prudencio, Ananth R Srinivasan, Olivia M Rifai, Virginia M-Y Lee, Leonard Petrucelli, Nancy M Bonini. Acta Neuropathol Commun 2019
19