A citation-based method for searching scientific literature

Quantitative analysis and clinico-pathological correlations of different dipeptide repeat protein pathologies in C9ORF72 mutation carriers.
Ian R A Mackenzie, Petra Frick, Friedrich A Grässer, Tania F Gendron, Leonard Petrucelli, Neil R Cashman, Dieter Edbauer, Elisabeth Kremmer, Johannes Prudlo, Dirk Troost, Manuela Neumann. Acta Neuropathol 2015
Times Cited: 150



Bidirectional transcripts of the expanded C9orf72 hexanucleotide repeat are translated into aggregating dipeptide repeat proteins.
Kohji Mori, Thomas Arzberger, Friedrich A Grässer, Ilse Gijselinck, Stephanie May, Kristin Rentzsch, Shih-Ming Weng, Martin H Schludi, Julie van der Zee, Marc Cruts, Christine Van Broeckhoven, Elisabeth Kremmer, Hans A Kretzschmar, Christian Haass, Dieter Edbauer. Acta Neuropathol 2013
Times Cited: 321




List of shared articles



Times cited

Autophagy and ALS: mechanistic insights and therapeutic implications.
Jason P Chua, Hortense De Calbiac, Edor Kabashi, Sami J Barmada. Autophagy 2022
7

Interactome screening of C9orf72 dipeptide repeats reveals VCP sequestration and functional impairment by polyGA.
Janja Božič, Helena Motaln, Anja Pucer Janež, Lara Markič, Priyanka Tripathi, Alfred Yamoah, Eleonora Aronica, Youn-Bok Lee, Raphael Heilig, Roman Fischer,[...]. Brain 2022
3

HDAC6 Interacts With Poly (GA) and Modulates its Accumulation in c9FTD/ALS.
Giulia Del Rosso, Yari Carlomagno, Tiffany W Todd, Caroline Y Jones, Mercedes Prudencio, Lillian M Daughrity, Mei Yue, Karen Jansen-West, Jimei Tong, Wei Shao,[...]. Front Cell Dev Biol 2022
0

Molecular Dynamics Study of Structure, Folding, and Aggregation of Poly-PR and Poly-GR Proteins.
Size Zheng, Ali Sahimi, Katherine S Shing, Muhammad Sahimi. Biophys J 2021
2

Altered Phase Separation and Cellular Impact in C9orf72-Linked ALS/FTD.
Daniel A Solomon, Rebekah Smikle, Matthew J Reid, Sarah Mizielinska. Front Cell Neurosci 2021
6

Molecular mechanisms underlying nucleotide repeat expansion disorders.
Indranil Malik, Chase P Kelley, Eric T Wang, Peter K Todd. Nat Rev Mol Cell Biol 2021
19

Multiple pathways of toxicity induced by C9orf72 dipeptide repeat aggregates and G4C2 RNA in a cellular model.
Frédéric Frottin, Manuela Pérez-Berlanga, F Ulrich Hartl, Mark S Hipp. Elife 2021
4

The porphyrin TMPyP4 inhibits elongation during the noncanonical translation of the FTLD/ALS-associated GGGGCC repeat in the C9orf72 gene.
Kohji Mori, Shiho Gotoh, Tomoko Yamashita, Ryota Uozumi, Yuya Kawabe, Shinji Tagami, Frits Kamp, Brigitte Nuscher, Dieter Edbauer, Christian Haass,[...]. J Biol Chem 2021
2

Elucidating the Role of Cerebellar Synaptic Dysfunction in C9orf72-ALS/FTD - a Systematic Review and Meta-Analysis.
Aleksandra Kaliszewska, Joseph Allison, Tarik-Tarkan Col, Christopher Shaw, Natalia Arias. Cerebellum 2021
0

Proteostasis deregulation as a driver of C9ORF72 pathogenesis.
Paulina Torres, Felipe Cabral-Miranda, Vicente Gonzalez-Teuber, Claudio Hetz. J Neurochem 2021
1

Modeling C9orf72-Related Frontotemporal Dementia and Amyotrophic Lateral Sclerosis in Drosophila.
Joanne L Sharpe, Nikki S Harper, Duncan R Garner, Ryan J H West. Front Cell Neurosci 2021
0

Aggregation and the Intrinsic Structural Disorder of Dipeptide Repeat Peptides of C9orf72-Related Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Characterized by NMR.
Bankala Krishnarjuna, Magdalena I Ivanova, Ayyalusamy Ramamoorthy. J Phys Chem B 2021
1

RNA toxicity in non-coding repeat expansion disorders.
Bart Swinnen, Wim Robberecht, Ludo Van Den Bosch. EMBO J 2020
81

Functional Roles of Long Non-coding RNAs in Motor Neuron Development and Disease.
Kuan-Wei Chen, Jun-An Chen. J Biomed Sci 2020
10

Development of disease-modifying drugs for frontotemporal dementia spectrum disorders.
Francesco Panza, Madia Lozupone, Davide Seripa, Antonio Daniele, Mark Watling, Gianluigi Giannelli, Bruno P Imbimbo. Nat Rev Neurol 2020
28

Reduced C9ORF72 function exacerbates gain of toxicity from ALS/FTD-causing repeat expansion in C9orf72.
Qiang Zhu, Jie Jiang, Tania F Gendron, Melissa McAlonis-Downes, Lulin Jiang, Amy Taylor, Sandra Diaz Garcia, Somasish Ghosh Dastidar, Maria J Rodriguez, Patrick King,[...]. Nat Neurosci 2020
74

Synaptic dysfunction induced by glycine-alanine dipeptides in C9orf72-ALS/FTD is rescued by SV2 replenishment.
Brigid K Jensen, Martin H Schuldi, Kevin McAvoy, Katelyn A Russell, Ashley Boehringer, Bridget M Curran, Karthik Krishnamurthy, Xinmei Wen, Thomas Westergard, Le Ma,[...]. EMBO Mol Med 2020
15

Chimeric Peptide Species Contribute to Divergent Dipeptide Repeat Pathology in c9ALS/FTD and SCA36.
Zachary T McEachin, Tania F Gendron, Nisha Raj, María García-Murias, Anwesha Banerjee, Ryan H Purcell, Patricia J Ward, Tiffany W Todd, Megan E Merritt-Garza, Karen Jansen-West,[...]. Neuron 2020
23

Divergence, Convergence, and Therapeutic Implications: A Cell Biology Perspective of C9ORF72-ALS/FTD.
Xiaoqiang Tang, Arturo Toro, Sahana T G, Junli Gao, Jessica Chalk, Björn Oskarsson, Ke Zhang. Mol Neurodegener 2020
10

Congenic expression of poly-GA but not poly-PR in mice triggers selective neuron loss and interferon responses found in C9orf72 ALS.
Katherine D LaClair, Qihui Zhou, Meike Michaelsen, Benedikt Wefers, Monika S Brill, Aleksandar Janjic, Birgit Rathkolb, Daniel Farny, Mikolaj Cygan, Martin Hrabe de Angelis,[...]. Acta Neuropathol 2020
15

Arginine-rich dipeptide-repeat proteins as phase disruptors in C9-ALS/FTD.
Hana M Odeh, James Shorter. Emerg Top Life Sci 2020
13

RNA-mediated toxicity in C9orf72 ALS and FTD.
Zachary T McEachin, Janani Parameswaran, Nisha Raj, Gary J Bassell, Jie Jiang. Neurobiol Dis 2020
11

Immiscible inclusion bodies formed by polyglutamine and poly(glycine-alanine) are enriched with distinct proteomes but converge in proteins that are risk factors for disease and involved in protein degradation.
Mona Radwan, Jordan D Lilley, Ching-Seng Ang, Gavin E Reid, Danny M Hatters. PLoS One 2020
4

Role of the C9ORF72 Gene in the Pathogenesis of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia.
Zongbing Hao, Rui Wang, Haigang Ren, Guanghui Wang. Neurosci Bull 2020
2

C9orf72 poly(GR) aggregation induces TDP-43 proteinopathy.
Casey N Cook, Yanwei Wu, Hana M Odeh, Tania F Gendron, Karen Jansen-West, Giulia Del Rosso, Mei Yue, Peizhou Jiang, Edward Gomes, Jimei Tong,[...]. Sci Transl Med 2020
49

Insights into disease mechanisms and potential therapeutics for C9orf72-related amyotrophic lateral sclerosis/frontotemporal dementia.
Delia Gagliardi, Gianluca Costamagna, Michela Taiana, Luca Andreoli, Fabio Biella, Margherita Bersani, Nereo Bresolin, Giacomo Pietro Comi, Stefania Corti. Ageing Res Rev 2020
2

The Development of C9orf72-Related Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Disorders.
Qijie Yang, Bin Jiao, Lu Shen. Front Genet 2020
7

Soluble and insoluble dipeptide repeat protein measurements in C9orf72-frontotemporal dementia brains show regional differential solubility and correlation of poly-GR with clinical severity.
Annelies Quaegebeur, Idoia Glaria, Tammaryn Lashley, Adrian M Isaacs. Acta Neuropathol Commun 2020
13

Review: Neuropathology of non-tau frontotemporal lobar degeneration.
M Neumann, I R A Mackenzie. Neuropathol Appl Neurobiol 2019
56

C9orf72-FTD/ALS pathogenesis: evidence from human neuropathological studies.
Sarat C Vatsavayai, Alissa L Nana, Jennifer S Yokoyama, William W Seeley. Acta Neuropathol 2019
35

Heterochromatin anomalies and double-stranded RNA accumulation underlie C9orf72 poly(PR) toxicity.
Yong-Jie Zhang, Lin Guo, Patrick K Gonzales, Tania F Gendron, Yanwei Wu, Karen Jansen-West, Aliesha D O'Raw, Sarah R Pickles, Mercedes Prudencio, Yari Carlomagno,[...]. Science 2019
99

Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathy.
Jeannie Chew, Casey Cook, Tania F Gendron, Karen Jansen-West, Giulia Del Rosso, Lillian M Daughrity, Monica Castanedes-Casey, Aishe Kurti, Jeannette N Stankowski, Matthew D Disney,[...]. Mol Neurodegener 2019
60

Repeat-associated non-AUG (RAN) translation: insights from pathology.
Monica Banez-Coronel, Laura P W Ranum. Lab Invest 2019
18

Molecular dynamics study of structure, folding, and aggregation of poly-glycine-alanine (Poly-GA).
Size Zheng, Ali Sahimi, Katherine S Shing, Muhammad Sahimi. J Chem Phys 2019
3

Repeat-associated non-AUG (RAN) translation mechanisms are running into focus for GGGGCC-repeat associated ALS/FTD.
Lindsey D Goodman, Nancy M Bonini. Prog Neurobiol 2019
7

Synaptic localization of C9orf72 regulates post-synaptic glutamate receptor 1 levels.
Shangxi Xiao, Paul M McKeever, Agnes Lau, Janice Robertson. Acta Neuropathol Commun 2019
20

Pathogenic Mechanisms and Therapy Development for C9orf72 Amyotrophic Lateral Sclerosis/Frontotemporal Dementia.
Jie Jiang, John Ravits. Neurotherapeutics 2019
20

CRISPR/Cas9 does not facilitate stable expression of long C9orf72 dipeptides in mice.
Sarah Ryan, Eleanor Hobbs, Sara Rollinson, Stuart M Pickering-Brown. Neurobiol Aging 2019
0

Glycine-alanine dipeptide repeats spread rapidly in a repeat length- and age-dependent manner in the fly brain.
Javier Morón-Oset, Tessa Supèr, Jacqueline Esser, Adrian M Isaacs, Sebastian Grönke, Linda Partridge. Acta Neuropathol Commun 2019
10

Disease Mechanisms of C9ORF72 Repeat Expansions.
Tania F Gendron, Leonard Petrucelli. Cold Spring Harb Perspect Med 2018
51

Sense-encoded poly-GR dipeptide repeat proteins correlate to neurodegeneration and uniquely co-localize with TDP-43 in dendrites of repeat-expanded C9orf72 amyotrophic lateral sclerosis.
Shahram Saberi, Jennifer E Stauffer, Jie Jiang, Sandra Diaz Garcia, Amy E Taylor, Derek Schulte, Takuya Ohkubo, Cheyenne L Schloffman, Marcus Maldonado, Michael Baughn,[...]. Acta Neuropathol 2018
100

CUG initiation and frameshifting enable production of dipeptide repeat proteins from ALS/FTD C9ORF72 transcripts.
Ricardos Tabet, Laure Schaeffer, Fernande Freyermuth, Melanie Jambeau, Michael Workman, Chao-Zong Lee, Chun-Chia Lin, Jie Jiang, Karen Jansen-West, Hussein Abou-Hamdan,[...]. Nat Commun 2018
74

In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment.
Qiang Guo, Carina Lehmer, Antonio Martínez-Sánchez, Till Rudack, Florian Beck, Hannelore Hartmann, Manuela Pérez-Berlanga, Frédéric Frottin, Mark S Hipp, F Ulrich Hartl,[...]. Cell 2018
177

ALS Genes in the Genomic Era and their Implications for FTD.
Hung Phuoc Nguyen, Christine Van Broeckhoven, Julie van der Zee. Trends Genet 2018
139


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